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Volumn 22, Issue 6, 2001, Pages 298-305

Genetic susceptibility to adverse drug reactions

Author keywords

[No Author keywords available]

Indexed keywords

AMONAFIDE; ANTIARRHYTHMIC AGENT; ANTILEUKEMIC AGENT; AZATHIOPRINE; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CYTOCHROME P450; DAPSONE; DIAZEPAM; FLUOROURACIL; HYDRALAZINE; ION CHANNEL; IRINOTECAN; ISONIAZID; MEPHENYTOIN; MERCAPTOPURINE; NEUROLEPTIC AGENT; NITRITE; NITROFURANTOIN; OPIATE; PERHEXILINE; PHENFORMIN; PHENYTOIN; PRIMAQUINE; PROCAINAMIDE; SULFONAMIDE; SUXAMETHONIUM; TOLBUTAMIDE; TRICYCLIC ANTIDEPRESSANT AGENT; UNINDEXED DRUG; WARFARIN;

EID: 0035369825     PISSN: 01656147     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-6147(00)01717-X     Document Type: Review
Times cited : (266)

References (87)
  • 1
    • 0032522873 scopus 로고    scopus 로고
    • Incidence of adverse drug reactions in hospitalized patients - A meta-analysis of prospective studies
    • (1998) J. Am. Med. Assoc. , vol.279 , pp. 1200-1205
    • Lazarou, J.1
  • 2
    • 0034720005 scopus 로고    scopus 로고
    • Adverse drug reactions in hospitalized patients: A critique of a meta-analysis
    • (2000) Medgenmed. , vol.6
    • Kvasz, M.1
  • 4
    • 0029066463 scopus 로고
    • Incidence of adverse drug events and potential adverse drug events - Implications for prevention
    • (1995) J. Am. Med. Assoc. , vol.274 , pp. 29-34
    • Bates, D.W.1
  • 7
    • 0032748555 scopus 로고    scopus 로고
    • Pharmacogenetics and pharmacogenomics: Why is this relevant to the clinical geneticist?
    • (1999) Clin. Genet. , vol.56 , pp. 247-258
    • Nebert, D.W.1
  • 11
    • 0031719374 scopus 로고    scopus 로고
    • The role of drug disposition in drug hypersensitivity: A chemical, molecular and clinical perspective
    • (1998) Chem. Res. Toxicol. , vol.11 , pp. 969-988
    • Park, B.K.1
  • 13
    • 0034638766 scopus 로고    scopus 로고
    • Pharmacogenetics and adverse drug reactions
    • (2000) Lancet , vol.356 , pp. 1667-1671
    • Meyer, U.A.1
  • 14
    • 0033939932 scopus 로고    scopus 로고
    • A functional polymorphism of the cytochrome P450 1A2 (CYP1A2) gene: Association with tardive dyskinesia in schizophrenia
    • (2000) Mol. Psychiatry , vol.5 , pp. 410-417
    • Basile, V.S.1
  • 15
    • 0033608466 scopus 로고    scopus 로고
    • Association of polymorphisms in the cytochrome P450 CYP2C9 with warfarin dose requirement and risk of bleeding complications
    • (1999) Lancet , vol.353 , pp. 717-719
    • Aithal, G.P.1
  • 17
    • 0029588524 scopus 로고
    • The role of cytochrome P450 enzymes in hepatic and extrahepatic human drug toxicity
    • (1995) Pharmacol. Ther. , vol.68 , pp. 385-424
    • Park, B.K.1
  • 22
    • 0001697297 scopus 로고    scopus 로고
    • Extension of a pilot study: Impact from the cytochrome P450 2D6 polymorphism on outcome and costs associated with severe mental illness
    • (2000) J. Clin. Psychopharmacol. , vol.20 , pp. 246-251
    • Chou, W.H.1
  • 23
    • 0031721749 scopus 로고    scopus 로고
    • Prevention of stroke in patients with nonvalvular atrial fibrillation
    • (1998) Neurology , vol.51 , pp. 674-681
    • Hart, R.G.1
  • 24
    • 0032910944 scopus 로고    scopus 로고
    • Frequency of major complications of aspirin, warfarin, and intravenous heparin for secondary stroke prevention - A population-based study
    • (1999) Ann. Intern. Med. , vol.130 , pp. 14-22
    • Petty, G.W.1
  • 25
    • 0026519541 scopus 로고
    • Hydroxylation of warfarin by human cDNA-expressed cytochrome-P-450 - A role for P-4502C9 in the etiology of (s)-warfarin drug-interactions
    • (1992) Chem. Res. Toxicol. , vol.5 , pp. 54-59
    • Rettie, A.E.1
  • 26
    • 0029564238 scopus 로고
    • Genetic polymorphism of CYP2C9 and its effect on warfarin maintenance dose requirement in patients undergoing anticoagulation therapy
    • (1995) Pharmacogenetics , vol.5 , pp. 389-392
    • Furuya, H.1
  • 27
    • 0030587544 scopus 로고    scopus 로고
    • Allelic variants of human cytochrome P450 2C9: Baculovirus-mediated expression, purification, structural characterization, substrate stereoselectivity, and prochiral selectivity of the wild-type and I359L mutant forms
    • (1996) Arch. Biochem. Biophys. , vol.333 , pp. 447-458
    • Haining, R.L.1
  • 28
    • 7844247934 scopus 로고    scopus 로고
    • Comparisons between in-vitro and in-vivo metabolism of (S)-warfarin: Catalytic activities of cDNA-expressed CYP2C9, its Leu359 variant and their mixture versus unbound clearance in patients with the corresponding CYP2C9 genotypes
    • (1998) Pharmacogenetics , vol.8 , pp. 365-373
    • Takahashi, H.1
  • 29
    • 0034283762 scopus 로고    scopus 로고
    • Influence of cytochrome P-450 CYP2C9 polymorphisms on warfarin sensitivity and risk of over-anticoagulation in patients on long-term treatment
    • (2000) Blood , vol.96 , pp. 1816-1819
    • Taube, J.1
  • 30
    • 0033884635 scopus 로고    scopus 로고
    • Cytochrome P450 polymorphisms are associated with reduced warfarin dose
    • (2000) Surgery , vol.128 , pp. 281-285
    • Freeman, B.D.1
  • 33
    • 0032494736 scopus 로고    scopus 로고
    • Multicentre randomised study of computerised anticoagulant dosage
    • (1998) Lancet , vol.352 , pp. 1505-1509
    • Poller, L.1
  • 34
    • 0034622382 scopus 로고    scopus 로고
    • Oral anticoagulation self-management and management by a specialist anticoagulation clinic: A randomised cross-over comparison
    • (2000) Lancet , vol.356 , pp. 97-102
    • Cromheecke, M.E.1
  • 37
    • 0034034158 scopus 로고    scopus 로고
    • Genetic polymorphism of thiopurine methyltransferase and its clinical relevance for childhood acute lymphoblastic leukemia
    • (2000) Leukemia , vol.14 , pp. 567-572
    • McLeod, H.L.1
  • 39
    • 0034671387 scopus 로고    scopus 로고
    • Polymorphisms of UDP-glucuronosyltransferase gene and irinotecan toxicity: A pharmacogenetic analysis
    • (2000) Cancer Res. , vol.60 , pp. 6921-6926
    • Ando, Y.1
  • 40
    • 0033656847 scopus 로고    scopus 로고
    • Association analysis of drug metabolizing enzyme gene polymorphisms in HIV-positive patients with co-trimoxazole hypersensitivity
    • (2000) Pharmacogenetics , vol.10 , pp. 705-713
    • Pirmohamed, M.1
  • 41
    • 0031787340 scopus 로고
    • Mechanisms of idiosyncratic hypersensitivity reactions to antiepileptic drugs
    • (1989) Epilepsia , vol.39 , Issue.SUPPL. 7
    • Leeder, J.S.1
  • 42
  • 43
    • 0031826404 scopus 로고    scopus 로고
    • No association between tacrine transaminitis and the glutathione transferase theta genotype in patients with Alzheimer's disease
    • (1998) Pharmacogenetics , vol.8 , pp. 353-355
    • DeSousa, M.1
  • 46
    • 0030934850 scopus 로고    scopus 로고
    • Molecular diagnosis of thiopurine S-methyltransferase deficiency: Genetic basis for azathioprine and mercaptopurine intolerance
    • (1997) Ann. Intern. Med. , vol.126 , pp. 608-614
    • Yates, C.R.1
  • 47
    • 0025837127 scopus 로고
    • Altered mercaptopurine metabolism, toxic effects, and dosage requirement in a thiopurine methyltransferase-deficient child with acute lymphocytic leukemia
    • (1991) J. Pediatr. , vol.119 , pp. 985-989
    • Evans, W.E.1
  • 48
    • 0027401302 scopus 로고
    • Azathioprine-induced myelosuppression in thiopurine methyltransferase deficient heart transplant recipient
    • (1993) Lancet , vol.341 , pp. 436
    • Schutz, E.1
  • 49
    • 0025331198 scopus 로고
    • Genetic variation in response to 6-mercaptopurine for childhood acute lymphoblastic leukaemia
    • (1990) Lancet , vol.336 , pp. 225-259
    • Lennard, L.1
  • 50
    • 0033486029 scopus 로고    scopus 로고
    • Mercaptopurine therapy intolerance and heterozygosity at the thiopurine S-methyltransferase gene locus
    • (1999) J. Natl. Cancer Inst. , vol.91 , pp. 2001-2008
    • Relling, M.V.1
  • 51
    • 0033135738 scopus 로고    scopus 로고
    • Prognostic importance of 6-mercaptopurine dose intensity in acute lymphoblastic leukemia
    • (1999) Blood , vol.93 , pp. 2817-2823
    • Relling, M.V.1
  • 52
    • 0033519986 scopus 로고    scopus 로고
    • High incidence of secondary brain tumours after radiotherapy and antimetabolites
    • (1999) Lancet , vol.354 , pp. 34-39
    • Relling, M.V.1
  • 53
  • 55
    • 0032519431 scopus 로고    scopus 로고
    • Genetic predisposition to the metabolism of irinotecan (CPT-11). Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes
    • (1998) J. Clin. Invest. , vol.101 , pp. 847-854
    • Iyer, L.1
  • 56
    • 0032934383 scopus 로고    scopus 로고
    • Phenotype-genotype correlation of in vitro SN-38 (active metabolite of irinotecan) and bilirubin glucuronidation in human liver tissue with UGT1A1 promoter polymorphism
    • (1999) Clin. Pharmacol. Ther. , vol.65 , pp. 576-582
    • Iyer, L.1
  • 57
    • 0029892497 scopus 로고    scopus 로고
    • P-glycoprotein in the blood-brain-barrier of mice influences the brain penetration and pharmacological activity of many drugs
    • (1996) J. Clin. Invest. , vol.97 , pp. 2517-2524
    • Schinkel, A.H.1
  • 58
    • 0034724324 scopus 로고    scopus 로고
    • Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo
    • (2000) Proc. Natl. Acad. Sci. U.S.A. , vol.97 , pp. 3473-3478
    • Hoffmeyer, S.1
  • 61
    • 0034701812 scopus 로고    scopus 로고
    • A transcription-activating polymorphism in the ACHE promoter associated with acute sensitivity to anti-acetylcholinesterases
    • (2000) Hum. Mol. Genet. , vol.9 , pp. 1273-1281
    • Shapira, M.1
  • 62
    • 0030860288 scopus 로고    scopus 로고
    • Association between β2-adrenoceptor polymorphism and susceptibility to bronchodilator desensitization in moderately severe stable asthmatics
    • (1997) Lancet , vol.350 , pp. 995-999
    • Tan, S.1
  • 64
    • 0032982269 scopus 로고    scopus 로고
    • Association of the MscI polymorphism of the dopamine D3 receptor gene with tardive dyskinesia in schizophrenia
    • (1999) Neuropsychopharmacology , vol.21 , pp. 17-27
    • Basile, V.S.1
  • 65
    • 0034087446 scopus 로고    scopus 로고
    • Ryanodine receptor mutations in malignant hyperthermia and central core disease
    • (2000) Hum. Mutat. , vol.15 , pp. 410-417
    • McCarthy, T.V.1
  • 67
    • 0033635776 scopus 로고    scopus 로고
    • Potassium channels: Molecular defects, diseases, and therapeutic opportunities
    • (2000) Pharmacol. Rev. , vol.52 , pp. 557-594
    • Shieh, C.C.1
  • 68
    • 0033574273 scopus 로고    scopus 로고
    • MiRP1 forms IKr potassium channels with HERG and is associated with cardiac arrhythmia
    • (1999) Cell , vol.97 , pp. 175-187
    • Abbott, G.W.1
  • 70
    • 0034605712 scopus 로고    scopus 로고
    • Idiosyncratic drug reactions: The reactive metabolite syndromes
    • (2000) Lancet , vol.356 , pp. 1587-1591
    • Knowles, S.R.1
  • 72
    • 0344721480 scopus 로고    scopus 로고
    • Complete sequence and gene map of a human major histocompatibility complex
    • (1999) Nature , vol.401 , pp. 921-923
  • 73
    • 0027534914 scopus 로고
    • An allelic polymorphism within the human tumor-necrosis-factor-α promoter region is strongly associated with HLA-A1, HLA-B8, and HLA-DR3 alleles
    • (1993) J. Exp. Med. , vol.177 , pp. 557-560
    • Wilson, A.G.1
  • 75
  • 76
    • 0022377259 scopus 로고
    • Genetic predisposition to phenytoin-induced birth defects
    • (1985) Lancet , vol.2 , pp. 746-749
    • Strickler, S.M.1
  • 77
    • 0032748789 scopus 로고    scopus 로고
    • Concordance of primary generalised epilepsy and carbamazepine hypersensitivity in monozygotic twins
    • (1999) Postgrad. Med. J. , vol.75 , pp. 680-681
    • Edwards, S.G.1
  • 79
    • 0025721852 scopus 로고
    • Carbamazepine hypersensitivity: Assessment of clinical and in vitro chemical cross-reactivity with phenytoin and oxcarbazepine
    • (1991) Br. J. Clin. Pharmacol. , vol.32 , pp. 741-749
    • Pirmohamed, M.1
  • 80
    • 0028352066 scopus 로고
    • Characterization of the microsomal epoxide hydrolase gene in patients with anticonvulsant adverse drug reactions
    • (1994) Pharmacogenetics , vol.4 , pp. 142-153
    • Gaedigk, A.1
  • 81
    • 0028880593 scopus 로고
    • Genetic analysis of microsomal epoxide hydrolase in patients with carbamazepine hypersensitivity
    • (1995) Biochem. Pharmacol. , vol.50 , pp. 1353-1359
    • Green, V.J.1
  • 82
    • 0035836342 scopus 로고    scopus 로고
    • TNF-α promoter region gene polymorphisms in carbamazepine-hypersensitive patients
    • in press
    • Neurology
    • Pirmohamed, M.1
  • 83
    • 0007932349 scopus 로고    scopus 로고
    • Interpretation of results from genetic studies of multifactorial diseases
    • (1999) Lancet , vol.354 , Issue.SUPPL. 1
    • Todd, J.A.1
  • 84
    • 0034660560 scopus 로고    scopus 로고
    • Pharmacogenetics and the practice of medicine
    • (2000) Nature , vol.405 , pp. 857-865
    • Roses, A.D.1
  • 85
    • 0035865322 scopus 로고    scopus 로고
    • A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms
    • (2001) Nature , vol.409 , pp. 928-933
  • 87
    • 0033816985 scopus 로고    scopus 로고
    • Testing drug response in the presence of genetic information: Sampling issues for clinical trials
    • (2000) Pharmacogenetics , vol.10 , pp. 503-510
    • Cardon, L.R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.