메뉴 건너뛰기




Volumn 42, Issue 3, 1996, Pages 347-353

The effect of fluconazole and ketoconazole on the metabolism of sulphamethoxazole

Author keywords

Fluconazole; Inhibition; Ketoconazole; Sulphamethoxazole hydroxylamine; Toxicity metabolism

Indexed keywords

COTRIMOXAZOLE; CYTOCHROME P450; DRUG METABOLITE; FLUCONAZOLE; KETOCONAZOLE; SULFAMETHOXAZOLE; TRIMETHOPRIM;

EID: 0029836423     PISSN: 03065251     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2125.1996.40110.x     Document Type: Article
Times cited : (42)

References (47)
  • 1
    • 0027082592 scopus 로고
    • Drug hypersensitivity reactions and human immunodeficiency virus disease
    • Bayard PJ, Berger TG, Jacobson MA. Drug hypersensitivity reactions and human immunodeficiency virus disease. J Acquir Immune Defic Syndr 1992; 5: 1237-1257.
    • (1992) J Acquir Immune Defic Syndr , vol.5 , pp. 1237-1257
    • Bayard, P.J.1    Berger, T.G.2    Jacobson, M.A.3
  • 2
    • 0026758528 scopus 로고
    • Comparing risk estimates of sulfonamide-induced agranulocytosis from the Swedish Drug Monitoring System and a case-control study
    • Keisu M, Ekman E, Wiholm B-E. Comparing risk estimates of sulfonamide-induced agranulocytosis from the Swedish Drug Monitoring System and a case-control study. Eur J Clin Pharmacol 1992; 43: 211-214.
    • (1992) Eur J Clin Pharmacol , vol.43 , pp. 211-214
    • Keisu, M.1    Ekman, E.2    Wiholm, B.-E.3
  • 3
    • 0028143526 scopus 로고
    • Management of adverse reactions to trimethoprim-sulfamethoxazole in human immunodeficiency virus-infected patients
    • Jung AC, Paauw DS. Management of adverse reactions to trimethoprim-sulfamethoxazole in human immunodeficiency virus-infected patients. Arch Intern Med 1994; 154: 2402-2406.
    • (1994) Arch Intern Med , vol.154 , pp. 2402-2406
    • Jung, A.C.1    Paauw, D.S.2
  • 4
    • 0027141363 scopus 로고
    • Clinical manifestations of AIDS in the era of Pneumocystis prophylaxis
    • Hoover DR, Sahh A, Bacellar H, et al. Clinical manifestations of AIDS in the era of Pneumocystis prophylaxis. N Engl J Med 1993; 329: 1922-1926.
    • (1993) N Engl J Med , vol.329 , pp. 1922-1926
    • Hoover, D.R.1    Sahh, A.2    Bacellar, H.3
  • 5
    • 0021259408 scopus 로고
    • Adverse reactions to trimethoprim-sulfamethoxazole in patients with the acquired immunodeficiency syndrome
    • Gordin FM, Simon GL, Wofsy CB, Mills J. Adverse reactions to trimethoprim-sulfamethoxazole in patients with the acquired immunodeficiency syndrome. Ann Intern Med 1984; 100: 495-499.
    • (1984) Ann Intern Med , vol.100 , pp. 495-499
    • Gordin, F.M.1    Simon, G.L.2    Wofsy, C.B.3    Mills, J.4
  • 6
    • 0020108735 scopus 로고
    • Adverse reactions to trimethoprim-sulfamethoxazole in hospitalised patients
    • Jick H. Adverse reactions to trimethoprim-sulfamethoxazole in hospitalised patients. Rev Infect Dis 1982; 4: 426-428.
    • (1982) Rev Infect Dis , vol.4 , pp. 426-428
    • Jick, H.1
  • 7
    • 0027433117 scopus 로고
    • In vitro cytotoxicity as a marker of hypersensitivity to sulphamethoxazole in patients with HIV
    • Carr A, Tindall B, Penny R, Cooper DA. In vitro cytotoxicity as a marker of hypersensitivity to sulphamethoxazole in patients with HIV. Clin Exp Immunol 1993; 94: 21-25.
    • (1993) Clin Exp Immunol , vol.94 , pp. 21-25
    • Carr, A.1    Tindall, B.2    Penny, R.3    Cooper, D.A.4
  • 8
    • 0023846286 scopus 로고
    • Synthesis and in vitro toxicity of hydroxylamine metabolites of sulfonamides
    • Rieder MJ, Uetrecht J, Shear NH, Spielberg SP. Synthesis and in vitro toxicity of hydroxylamine metabolites of sulfonamides. J Pharmacol Exp Ther 1988; 244: 724-728.
    • (1988) J Pharmacol Exp Ther , vol.244 , pp. 724-728
    • Rieder, M.J.1    Uetrecht, J.2    Shear, N.H.3    Spielberg, S.P.4
  • 9
    • 0028950322 scopus 로고
    • Toxicity of sulfonamide reactive metabolites in HIV-infected, HTLV-infected and non-infected cells
    • Rieder MJ, Krause R, Bird IA, Dekaban GA. Toxicity of sulfonamide reactive metabolites in HIV-infected, HTLV-infected and non-infected cells. J Acq Im Defie Synd Hum Retrovirol 1995; 8: 134-140.
    • (1995) J Acq Im Defie Synd Hum Retrovirol , vol.8 , pp. 134-140
    • Rieder, M.J.1    Krause, R.2    Bird, I.A.3    Dekaban, G.A.4
  • 10
    • 0028618807 scopus 로고
    • Immunochemical analysis of sulfonamide drug allergy: Identification of sulfamethoxazole-substituted human serum proteins
    • Meekins CV, Sullivan TJ, Gruchalla RS. Immunochemical analysis of sulfonamide drug allergy: Identification of sulfamethoxazole-substituted human serum proteins. J Allergy Clin Immunol 1994; 94: 1017-1024.
    • (1994) J Allergy Clin Immunol , vol.94 , pp. 1017-1024
    • Meekins, C.V.1    Sullivan, T.J.2    Gruchalla, R.S.3
  • 11
    • 0027178089 scopus 로고
    • Altered patterns of drug metabolism in patients with acquired immunodeficiency syndrome
    • Lee BL, Wong D, Benowitz NL, Sullam PM. Altered patterns of drug metabolism in patients with acquired immunodeficiency syndrome. Clin Pharmacol Ther 1993; 53: 529-535.
    • (1993) Clin Pharmacol Ther , vol.53 , pp. 529-535
    • Lee, B.L.1    Wong, D.2    Benowitz, N.L.3    Sullam, P.M.4
  • 12
    • 0025740328 scopus 로고
    • The effects of preincubation with cimetidine on the N-hydroxylation of dapsone by human liver microsomes
    • Tingle MD, Coleman MD, Park BK. The effects of preincubation with cimetidine on the N-hydroxylation of dapsone by human liver microsomes. Br J Clin Pharmacol 1991; 32: 120-123.
    • (1991) Br J Clin Pharmacol , vol.32 , pp. 120-123
    • Tingle, M.D.1    Coleman, M.D.2    Park, B.K.3
  • 13
    • 0025038855 scopus 로고
    • The use of cimetidine as a selective inhibitor of dapsone N-hydroxylation in man
    • Coleman MD, Scott AK, Breckenridge AM, Park BK. The use of cimetidine as a selective inhibitor of dapsone N-hydroxylation in man. Br J Clin Pharmacol 1990; 30: 761-767.
    • (1990) Br J Clin Pharmacol , vol.30 , pp. 761-767
    • Coleman, M.D.1    Scott, A.K.2    Breckenridge, A.M.3    Park, B.K.4
  • 14
    • 0026794121 scopus 로고
    • The use of cimetidine to reduce dapsone-dependent methaemoglobinaemia in dermatitis herpetiformis
    • Coleman MD, Rhodes LE, Scott AK, et al. The use of cimetidine to reduce dapsone-dependent methaemoglobinaemia in dermatitis herpetiformis. Br J Clin Pharmacol 1992; 34: 244-249.
    • (1992) Br J Clin Pharmacol , vol.34 , pp. 244-249
    • Coleman, M.D.1    Rhodes, L.E.2    Scott, A.K.3
  • 15
    • 0028966720 scopus 로고
    • Cimetidine improves the therapeutic/toxic ratio of dapsone in patients on chronic dapsone therapy
    • Rhodes LE, Tingle MD, Park BK, Chu P, Verbov JL, Friedmann PS. Cimetidine improves the therapeutic/toxic ratio of dapsone in patients on chronic dapsone therapy. Br J Dermatol 1995; 132: 257-262.
    • (1995) Br J Dermatol , vol.132 , pp. 257-262
    • Rhodes, L.E.1    Tingle, M.D.2    Park, B.K.3    Chu, P.4    Verbov, J.L.5    Friedmann, P.S.6
  • 16
    • 0026794615 scopus 로고
    • Cimetidine-carbaryl interaction in humans: Evidence for an active metabolite of carbaryl
    • May DG, Naukam RJ, Kambam JR, Branch RA. Cimetidine-carbaryl interaction in humans: Evidence for an active metabolite of carbaryl. J Pharmacol Exp Ther 1992; 292:1057-1061.
    • (1992) J Pharmacol Exp Ther , vol.292 , pp. 1057-1061
    • May, D.G.1    Naukam, R.J.2    Kambam, J.R.3    Branch, R.A.4
  • 17
    • 0028986887 scopus 로고
    • 4-Hydroxylation of sulfamethoxazole by cytochrome P450 of the cytochrome P450 2C subfamily and reduction of sulfamethoxazole hydroxylamine in human and rat hepatic microsomes
    • 4-Hydroxylation of sulfamethoxazole by cytochrome P450 of the cytochrome P450 2C subfamily and reduction of sulfamethoxazole hydroxylamine in human and rat hepatic microsomes. Drug Metab Dispos 1995; 23: 406-414.
    • (1995) Drug Metab Dispos , vol.23 , pp. 406-414
    • Cribb, A.E.1    Spielberg, S.P.2    Griffin, G.P.3
  • 18
    • 0028858960 scopus 로고
    • Cytochrome P450 inhibitors: Evaluation of specificities in the in vitro metabolism of therapeutic agents by human liver microsomes
    • Newton DJ, Wang RW, Lu AYH. Cytochrome P450 inhibitors: Evaluation of specificities in the in vitro metabolism of therapeutic agents by human liver microsomes. Drug Metab Dispos 1995; 23: 154-158.
    • (1995) Drug Metab Dispos , vol.23 , pp. 154-158
    • Newton, D.J.1    Wang, R.W.2    Lu, A.Y.H.3
  • 19
    • 0025949455 scopus 로고
    • Comparative effects of the anti-mycotic drugs ketoconazole, fluconazole, itraconazole and terbinafine on the metabolism of cyclosporine by human liver microsomes
    • Back DJ, Tjia JF. Comparative effects of the anti-mycotic drugs ketoconazole, fluconazole, itraconazole and terbinafine on the metabolism of cyclosporine by human liver microsomes. Br J Clin Pharmacol 1991; 32: 624-626.
    • (1991) Br J Clin Pharmacol , vol.32 , pp. 624-626
    • Back, D.J.1    Tjia, J.F.2
  • 20
    • 0026647577 scopus 로고
    • Contrasting effects of fluconazole and ketoconazole on phenytoin and testosterone disposition in man
    • Touchette MA, Chandrasekar PH, Milad MA, Edwards DJ. Contrasting effects of fluconazole and ketoconazole on phenytoin and testosterone disposition in man. Br J Clin Pharmacol 1992; 34: 75-78.
    • (1992) Br J Clin Pharmacol , vol.34 , pp. 75-78
    • Touchette, M.A.1    Chandrasekar, P.H.2    Milad, M.A.3    Edwards, D.J.4
  • 21
    • 0025760346 scopus 로고
    • Effect of fluconazole on the disposition of phenytoin
    • Blum RA, Wilton JH, Hilligoss DM. et al. Effect of fluconazole on the disposition of phenytoin. Clin Pharmacol Ther 1991; 49: 420-425.
    • (1991) Clin Pharmacol Ther , vol.49 , pp. 420-425
    • Blum, R.A.1    Wilton, J.H.2    Hilligoss, D.M.3
  • 22
    • 0026058222 scopus 로고
    • Relationship between phenytoin and tolbutamide hydroxylations in human liver microsomes
    • Doecke CJ, Veronese ME, Pond SM, et al. Relationship between phenytoin and tolbutamide hydroxylations in human liver microsomes. Br J Clin Pharmacol 1991; 31: 125-130.
    • (1991) Br J Clin Pharmacol , vol.31 , pp. 125-130
    • Doecke, C.J.1    Veronese, M.E.2    Pond, S.M.3
  • 23
    • 0027283488 scopus 로고
    • Ketoconazole and fluconazole drug interactions
    • Baciewicz AM, Baciewicz FA. Ketoconazole and fluconazole drug interactions. Arch Intern Med 1993; 153: 1970-1976.
    • (1993) Arch Intern Med , vol.153 , pp. 1970-1976
    • Baciewicz, A.M.1    Baciewicz, F.A.2
  • 24
    • 0023921505 scopus 로고
    • Cyclosporine metabolism in human liver. Identification of a cytochrome P450III gene family as the major cyclosporine-metabolising enzyme explains interactions of cyclosporine with other drugs
    • Kronbach T, Fischer V, Meyer UA. Cyclosporine metabolism in human liver. Identification of a cytochrome P450III gene family as the major cyclosporine-metabolising enzyme explains interactions of cyclosporine with other drugs. Clin Pharmacol Ther 1988; 43: 630-635.
    • (1988) Clin Pharmacol Ther , vol.43 , pp. 630-635
    • Kronbach, T.1    Fischer, V.2    Meyer, U.A.3
  • 25
    • 0026552198 scopus 로고
    • Sulfamethoxazole is metabolised to the hydroxylamine in humans
    • Cribb AE, Spielberg SP. Sulfamethoxazole is metabolised to the hydroxylamine in humans. Clin Pharmacol Ther 1992; 51: 522-526.
    • (1992) Clin Pharmacol Ther , vol.51 , pp. 522-526
    • Cribb, A.E.1    Spielberg, S.P.2
  • 26
    • 0029416939 scopus 로고
    • N-Hydroxylation of dapsone by multiple enzymes of cytochrome P450: Implications for inhibition of haemotoxicity
    • Gill HJ, Tingle MD, Park BK. N-Hydroxylation of dapsone by multiple enzymes of cytochrome P450: implications for inhibition of haemotoxicity. Br J Clin Pharmacol 1995; 40: 531-538.
    • (1995) Br J Clin Pharmacol , vol.40 , pp. 531-538
    • Gill, H.J.1    Tingle, M.D.2    Park, B.K.3
  • 28
    • 0000732707 scopus 로고
    • Effect of azole antifungals on human microsomal metabolism of diclofenac and midazolam
    • Hargreaves JA, Jezequel S, Houston JB. Effect of azole antifungals on human microsomal metabolism of diclofenac and midazolam. Br J Clin Pharmacol 1994; 38: 175P.
    • (1994) Br J Clin Pharmacol , vol.38
    • Hargreaves, J.A.1    Jezequel, S.2    Houston, J.B.3
  • 30
    • 0027468346 scopus 로고
    • Terfenadine-ketoconazole interaction. Pharmacokinetic and electrocardiographic consequences
    • Honig PK, Wortham DC, Zamani K, Conner DP, Mullin JC, Cantilena LR. Terfenadine-ketoconazole interaction. Pharmacokinetic and electrocardiographic consequences. JAMA 1993; 269: 1513-1518.
    • (1993) JAMA , vol.269 , pp. 1513-1518
    • Honig, P.K.1    Wortham, D.C.2    Zamani, K.3    Conner, D.P.4    Mullin, J.C.5    Cantilena, L.R.6
  • 31
    • 0023946858 scopus 로고
    • Fluconazole in the management of oropharyngeal candidosis in a predominantly HIV antibody-positive group of patients
    • Dupont B, Drouhet E. Fluconazole in the management of oropharyngeal candidosis in a predominantly HIV antibody-positive group of patients. J Med Vet Mycol 1988; 26: 67-71.
    • (1988) J Med Vet Mycol , vol.26 , pp. 67-71
    • Dupont, B.1    Drouhet, E.2
  • 32
    • 0028969761 scopus 로고
    • Pathogenesis of hypersensitivity reactions to drugs in patients with HIV infection: Allergic or toxic
    • Koopmans PP, van der Ven AJAM, Vree TB, van der Meer JWM. Pathogenesis of hypersensitivity reactions to drugs in patients with HIV infection: Allergic or toxic. AIDS 1995; 9: 217-222.
    • (1995) AIDS , vol.9 , pp. 217-222
    • Koopmans, P.P.1    Van Der Ven, A.J.A.M.2    Vree, T.B.3    Van Der Meer, J.W.M.4
  • 33
    • 0026459382 scopus 로고
    • Speculations on the substrate structure-activity relationship (SSAR) of cytochrome P450 enzymes
    • Smith DA, Jones BC. Speculations on the substrate structure-activity relationship (SSAR) of cytochrome P450 enzymes. Biochem Pharmacol 1992; 44: 2089-2098.
    • (1992) Biochem Pharmacol , vol.44 , pp. 2089-2098
    • Smith, D.A.1    Jones, B.C.2
  • 34
    • 0029128881 scopus 로고
    • The substrate binding site of human liver cytochrome P450 2C9; An approach using designed trienilic acid derivatives and molecular modelling
    • Mancy A, Broto P, Dijols S, Dansette PM, Mansuy D. The substrate binding site of human liver cytochrome P450 2C9; An approach using designed trienilic acid derivatives and molecular modelling. Biochemistry 1995; 34: 10365-10375.
    • (1995) Biochemistry , vol.34 , pp. 10365-10375
    • Mancy, A.1    Broto, P.2    Dijols, S.3    Dansette, P.M.4    Mansuy, D.5
  • 35
    • 0026595179 scopus 로고
    • Effects of imidazole derivatives on cytochrome P450 from human hepatocytes in primary culture
    • Maurice M, Pichard L, Daujat M, et al. Effects of imidazole derivatives on cytochrome P450 from human hepatocytes in primary culture. FASEB J 1992; 6: 752-758.
    • (1992) FASEB J , vol.6 , pp. 752-758
    • Maurice, M.1    Pichard, L.2    Daujat, M.3
  • 40
    • 0025219525 scopus 로고
    • Drug interactions with fluconazole
    • Lazar JD, Wilner KD. Drug interactions with fluconazole. Rev Infect Dis 1990; 12: S327-S333.
    • (1990) Rev Infect Dis , vol.12
    • Lazar, J.D.1    Wilner, K.D.2
  • 41
    • 0024584277 scopus 로고
    • Diagnosis of sulfonamide hypersensitivity reactions by in vitro 'rechallenge' with hydroxylamine metabolites
    • Rieder MJ, Uetrecht J, Shear NH, Cannon M, Miller M, Spielberg SP. Diagnosis of sulfonamide hypersensitivity reactions by in vitro 'rechallenge' with hydroxylamine metabolites. Ann Intern Med 1989; 110: 286-289.
    • (1989) Ann Intern Med , vol.110 , pp. 286-289
    • Rieder, M.J.1    Uetrecht, J.2    Shear, N.H.3    Cannon, M.4    Miller, M.5    Spielberg, S.P.6
  • 42
    • 0029892271 scopus 로고    scopus 로고
    • Covalent binding of sulfamethoxazole reactive metabolites to human and rat liver subcellular fractions assessed by immunochemical detection
    • Cribb AE, Nuss CE, Alberts DW, et al Covalent binding of sulfamethoxazole reactive metabolites to human and rat liver subcellular fractions assessed by immunochemical detection. Chem Res Toxicol 1996; 9: 500-507.
    • (1996) Chem Res Toxicol , vol.9 , pp. 500-507
    • Cribb, A.E.1    Nuss, C.E.2    Alberts, D.W.3
  • 43
    • 0025947068 scopus 로고
    • Reactions of the nitroso and hydroxylamine metabolites of sulfamethoxazole with reduced glutathione
    • Cribb AE, Miller M, Leeder JS, Hill J, Spielberg SP. Reactions of the nitroso and hydroxylamine metabolites of sulfamethoxazole with reduced glutathione. Drug Metab Dispos 1991; 19: 900-906.
    • (1991) Drug Metab Dispos , vol.19 , pp. 900-906
    • Cribb, A.E.1    Miller, M.2    Leeder, J.S.3    Hill, J.4    Spielberg, S.P.5
  • 44
    • 0028963254 scopus 로고
    • Time-course of toxicity of reactive sulfonamide metabolites
    • Rieder MJ, Krause R, Bird IA. Time-course of toxicity of reactive sulfonamide metabolites. Toxicology 1995; 95: 141-146.
    • (1995) Toxicology , vol.95 , pp. 141-146
    • Rieder, M.J.1    Krause, R.2    Bird, I.A.3
  • 45
    • 0024466393 scopus 로고
    • Bioactivation of dapsone to a cytotoxic metabolite by human hepatic microsomal enzymes
    • Coleman MD, Breckenridge AM, Park BK. Bioactivation of dapsone to a cytotoxic metabolite by human hepatic microsomal enzymes. Br J Clin Pharmacol 1989; 28: 389-395.
    • (1989) Br J Clin Pharmacol , vol.28 , pp. 389-395
    • Coleman, M.D.1    Breckenridge, A.M.2    Park, B.K.3
  • 47
    • 0026096515 scopus 로고
    • Cyclosporine dose reduction by ketoconazole administration in renal transplant recipients
    • First MR, Schroeder TJ, Alexander JW, et al. Cyclosporine dose reduction by ketoconazole administration in renal transplant recipients. Transplantation 1991; 51: 365-370.
    • (1991) Transplantation , vol.51 , pp. 365-370
    • First, M.R.1    Schroeder, T.J.2    Alexander, J.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.