Exposure of mice to the nitroso metabolite of sulfamethoxazole stimulates interleukin 5 production by CD4 + T-cells

Toxicology

Volumn 206, Issue 2, 2005, Pages 221-231

  Hopkins, Josephine E ^a   Naisbitt, Dean J ^a   Humphreys, Neil ^b   Dearman, Rebecca J ^b   Kimber, Ian ^b   Park, B Kevin ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b JEALOTT S HILL INTERNATIONAL RESEARCH CENTRE   (United Kingdom)

Author keywords

Cytokine; Drug allergy; Drug metabolism; Sulfamethoxazole

Indexed keywords

1 CHLORO 2,4 DINITROBENZENE; ALLERGEN; CD4 ANTIGEN; CD8 ANTIGEN; CYTOKINE; DRUG METABOLITE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 4; INTERLEUKIN 5; NITROSO DERIVATIVE; NITROSOBENZENE; NITROSOSULFAMETHOXAZOLE; SULFAMETHOXAZOLE; SULFAMETHOXAZOLE HYDROXYLAMINE; THYMIDINE; TRIMELLITIC ANHYDRIDE; TRITIUM; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ACTIVATION; CELL INTERACTION; CELL PROLIFERATION; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DEPLETION; DRUG HYPERSENSITIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; EXPOSURE; FEMALE; IMMUNE RESPONSE; IMMUNOSTIMULATION; LYMPH NODE; LYMPH NODE CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE; TH1 CELL; TH2 CELL;

ANIMALS; ANTI-INFECTIVE AGENTS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CYTOKINES; DINITROCHLOROBENZENE; DRUG HYPERSENSITIVITY; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; INTERLEUKIN-5; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; NITROSO COMPOUNDS; PHTHALIC ANHYDRIDES; SULFAMETHOXAZOLE; TH1 CELLS; TH2 CELLS;

EID: 10044277088     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2004.08.010     Document Type: Article

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