Covalent binding of the nitroso metabolite of sulfamethoxazole is important in induction of drug-specific T-cell responses in vivo

Molecular Pharmacology

Volumn 73, Issue 6, 2008, Pages 1769-1775

  Cheng, Linling ^a   Stewart, Benjamin J ^a   You, Qiang ^a   Petersen, Dennis R ^a   Ware, Joseph A ^b   Piccotti, Joseph R ^b   Kawabata, Thomas T ^b   Ju, Cynthia ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 (NITROSO) N (5 METHYL 1,2 OXAZOL 3 YL)BENZENESULFONAMIDE; ALBUMIN; BENZENESULFONAMIDE DERIVATIVE; IMMUNOGLOBULIN; NITROSO DERIVATIVE;

ALBUMIN BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AXILLARY LYMPH NODE; CELLULAR IMMUNITY; CONTROLLED STUDY; COVALENT BOND; DBA 1 MOUSE; DRUG PROTEIN BINDING; DRUG SPECIFICITY; FEMALE; IMMUNOGENICITY; IMMUNOGLOBULIN BLOOD LEVEL; IN VIVO STUDY; INGUINAL LYMPH NODE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN TARGETING; SPLEEN; T LYMPHOCYTE;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; FEMALE; MICE; MICE, INBRED DBA; MOLECULAR SEQUENCE DATA; NITROSO COMPOUNDS; SULFAMETHOXAZOLE; T-LYMPHOCYTES;

EID: 44249117831     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.107.043273     Document Type: Article

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