-
1
-
-
17644427034
-
Clinical relevance of preclinical testing for allergic side effects
-
Bala S, Weaver J, and Hastings KL (2005) Clinical relevance of preclinical testing for allergic side effects. Toxicology 209:195-200.
-
(2005)
Toxicology
, vol.209
, pp. 195-200
-
-
Bala, S.1
Weaver, J.2
Hastings, K.L.3
-
2
-
-
0027366993
-
Analysis of tetanus toxin peptide/DR recognition by human T cell receptors reconstituted into a murine T cell hybridoma
-
Blank U, Boitel B, Mege D, Ermonval M, and Acuto O (1993) Analysis of tetanus toxin peptide/DR recognition by human T cell receptors reconstituted into a murine T cell hybridoma. Eur J Immunol 23:3057-3065.
-
(1993)
Eur J Immunol
, vol.23
, pp. 3057-3065
-
-
Blank, U.1
Boitel, B.2
Mege, D.3
Ermonval, M.4
Acuto, O.5
-
3
-
-
0029068773
-
Heterogeneous T cell responses to beta-lactam-modified self-structures are observed in penicillin-allergic individuals
-
Brander C, Mauri-Hellweg D, Bettens F, Rolli H, Goldman M, and Pichler WJ (1995) Heterogeneous T cell responses to beta-lactam-modified self-structures are observed in penicillin-allergic individuals. J Immunol 155:2670-2678.
-
(1995)
J Immunol
, vol.155
, pp. 2670-2678
-
-
Brander, C.1
Mauri-Hellweg, D.2
Bettens, F.3
Rolli, H.4
Goldman, M.5
Pichler, W.J.6
-
4
-
-
0036434911
-
Non-covalent presentation of sulfamethoxazole to human CD4+ T cells is independent of distinct human leucocyte antigen-bound peptides
-
Burkhart C, Britschgi M, Strasser I, Depta JP, von Greyerz S, Barnaba V, and Pichler WJ (2002) Non-covalent presentation of sulfamethoxazole to human CD4+ T cells is independent of distinct human leucocyte antigen-bound peptides. Clin Exp Allergy 32:1635-1643.
-
(2002)
Clin Exp Allergy
, vol.32
, pp. 1635-1643
-
-
Burkhart, C.1
Britschgi, M.2
Strasser, I.3
Depta, J.P.4
Von Greyerz, S.5
Barnaba, V.6
Pichler, W.J.7
-
5
-
-
1542616264
-
Drug interaction with T-cell receptors: T-cell receptor density determines degree of cross-reactivity
-
Depta JP, Altznauer F, Gamerdinger K, Burkhart C, Weltzien HU, and Pichler WJ (2004) Drug interaction with T-cell receptors: T-cell receptor density determines degree of cross-reactivity. J Allergy Clin Immunol 113:519-527.
-
(2004)
J Allergy Clin Immunol
, vol.113
, pp. 519-527
-
-
Depta, J.P.1
Altznauer, F.2
Gamerdinger, K.3
Burkhart, C.4
Weltzien, H.U.5
Pichler, W.J.6
-
6
-
-
0030823184
-
Replicative senescence of T cells: Does the Hayflick Limit lead to immune exhaustion?
-
Effros RB and Pawelec G (1997) Replicative senescence of T cells: does the Hayflick Limit lead to immune exhaustion? Immunol Today 18:450-454.
-
(1997)
Immunol Today
, vol.18
, pp. 450-454
-
-
Effros, R.B.1
Pawelec, G.2
-
7
-
-
0030041092
-
Reactivity of mouse T-cell hybridomas expressing human Vbeta gene segments with staphylococcal and streptococcal superantigens
-
Fleischer B, Necker A, Leget C, Malissen B, and Romagne F (1996) Reactivity of mouse T-cell hybridomas expressing human Vbeta gene segments with staphylococcal and streptococcal superantigens. Infect Immun 64:987-994.
-
(1996)
Infect Immun
, vol.64
, pp. 987-994
-
-
Fleischer, B.1
Necker, A.2
Leget, C.3
Malissen, B.4
Romagne, F.5
-
8
-
-
0023921344
-
T cell stimulation by staphylococcal enterotoxins. Clonally variable response and requirement for major histocompatibility complex class II molecules on accessory or target cells
-
Fleischer B and Schrezenmeier H (1988) T cell stimulation by staphylococcal enterotoxins. Clonally variable response and requirement for major histocompatibility complex class II molecules on accessory or target cells. J Exp Med 167:1697-1707.
-
(1988)
J Exp Med
, vol.167
, pp. 1697-1707
-
-
Fleischer, B.1
Schrezenmeier, H.2
-
9
-
-
0023222687
-
4-Quinolone drugs affect cell cycle progression and function of human lymphocytes in vitro
-
Forsgren A, Schlossman SF, and Tedder TF (1987) 4-Quinolone drugs affect cell cycle progression and function of human lymphocytes in vitro. Antimicrob Agents Chemother 31:768-773.
-
(1987)
Antimicrob Agents Chemother
, vol.31
, pp. 768-773
-
-
Forsgren, A.1
Schlossman, S.F.2
Tedder, T.F.3
-
10
-
-
0037515534
-
A new type of metal recognition by human T cells: Contact residues for peptide-independent bridging of T cell receptor and major histocompatibility complex by nickel
-
Gamerdinger K, Moulon C, Karp DR, Van Bergen J, Koning F, Wild D, Pflugfelder U, and Weltzien HU (2003) A new type of metal recognition by human T cells: contact residues for peptide-independent bridging of T cell receptor and major histocompatibility complex by nickel. J Exp Med 197:1345-1353.
-
(2003)
J Exp Med
, vol.197
, pp. 1345-1353
-
-
Gamerdinger, K.1
Moulon, C.2
Karp, D.R.3
Van Bergen, J.4
Koning, F.5
Wild, D.6
Pflugfelder, U.7
Weltzien, H.U.8
-
11
-
-
0022460807
-
Purification to homogeneity of B cell stimulating factor. A molecule that stimulates proliferation of multiple lymphokine-dependent cell lines
-
Grabstein K, Eisenman J, Mochizuki D, Shanebeck K, Conlon P, Hopp T, March C, and Gillis S (1986) Purification to homogeneity of B cell stimulating factor. A molecule that stimulates proliferation of multiple lymphokine-dependent cell lines. J Exp Med 163:1405-1414.
-
(1986)
J Exp Med
, vol.163
, pp. 1405-1414
-
-
Grabstein, K.1
Eisenman, J.2
Mochizuki, D.3
Shanebeck, K.4
Conlon, P.5
Hopp, T.6
March, C.7
Gillis, S.8
-
13
-
-
0001637710
-
Identification of a monoclonal antibody specific for a murine T3 polypeptide
-
Leo O, Foo M, Sachs DH, Samelson LE, and Bluestone JA (1987) Identification of a monoclonal antibody specific for a murine T3 polypeptide. Proc Natl Acad Sci USA 84:1374-1378.
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 1374-1378
-
-
Leo, O.1
Foo, M.2
Sachs, D.H.3
Samelson, L.E.4
Bluestone, J.A.5
-
14
-
-
0024845198
-
Derivation of a T cell hybridoma variant deprived of functional T cell receptor alpha and beta chain transcripts reveals a nonfunctional alpha-mRNA of BW5147 origin
-
Letourneur F and Malissen B (1989) Derivation of a T cell hybridoma variant deprived of functional T cell receptor alpha and beta chain transcripts reveals a nonfunctional alpha-mRNA of BW5147 origin. Eur J Immunol 19:2269-2274.
-
(1989)
Eur J Immunol
, vol.19
, pp. 2269-2274
-
-
Letourneur, F.1
Malissen, B.2
-
15
-
-
0347933013
-
Detection of specific IgE to quinolones
-
Manfredi M, Severino M, Testi S, Macchia D, Ermini G, Pichler WJ, and Campi P (2004) Detection of specific IgE to quinolones. J Allergy Clin Immunol 113:155-160.
-
(2004)
J Allergy Clin Immunol
, vol.113
, pp. 155-160
-
-
Manfredi, M.1
Severino, M.2
Testi, S.3
Macchia, D.4
Ermini, G.5
Pichler, W.J.6
Campi, P.7
-
16
-
-
0029060517
-
Activation of drug-specific CD4+ and CD8+ T cells in individuals allergic to sulfonamides, phenytoin and carbamazepine
-
Mauri-Hellweg D, Bettens F, Mauri D, Brander C, Hunziker T, and Pichler WJ (1995) Activation of drug-specific CD4+ and CD8+ T cells in individuals allergic to sulfonamides, phenytoin and carbamazepine. J Immunol 155:462-472.
-
(1995)
J Immunol
, vol.155
, pp. 462-472
-
-
Mauri-Hellweg, D.1
Bettens, F.2
Mauri, D.3
Brander, C.4
Hunziker, T.5
Pichler, W.J.6
-
17
-
-
14844363448
-
Mechanisms that limit the in vitro proliferative potential of human CD8+ T lymphocytes
-
Migliaccio M, Raj K, Menzel O, and Rufer N (2005) Mechanisms that limit the in vitro proliferative potential of human CD8+ T lymphocytes. J Immunol 174:3335-3343.
-
(2005)
J Immunol
, vol.174
, pp. 3335-3343
-
-
Migliaccio, M.1
Raj, K.2
Menzel, O.3
Rufer, N.4
-
18
-
-
0344951264
-
Hypersensitivity reactions to carbamazepine: Characterization of the specificity, phenotype and cytokine profile of drug-specific T cell clones
-
Naisbitt DJ, Britschgi M, Wong G, Farrell J, Depta JP, Chadwick DW, Pichler WJ, Pirmohamed M, and Park BK (2003a) Hypersensitivity reactions to carbamazepine: characterization of the specificity, phenotype and cytokine profile of drug-specific T cell clones. Mol Pharmacol 63:732-741.
-
(2003)
Mol Pharmacol
, vol.63
, pp. 732-741
-
-
Naisbitt, D.J.1
Britschgi, M.2
Wong, G.3
Farrell, J.4
Depta, J.P.5
Chadwick, D.W.6
Pichler, W.J.7
Pirmohamed, M.8
Park, B.K.9
-
19
-
-
0038797941
-
Characterization of drug-specific T cells in lamotrigine hypersensitivity
-
Naisbitt DJ, Farrell J, Wong G, Depta JP, Dodd CC, Hopkins JE, Gibney CA, Chadwick DW, Pichler WJ, Pirmohamed M, et al. (2003b) Characterization of drug-specific T cells in lamotrigine hypersensitivity. J Allergy Clin Immunol 111:1393-1403.
-
(2003)
J Allergy Clin Immunol
, vol.111
, pp. 1393-1403
-
-
Naisbitt, D.J.1
Farrell, J.2
Wong, G.3
Depta, J.P.4
Dodd, C.C.5
Hopkins, J.E.6
Gibney, C.A.7
Chadwick, D.W.8
Pichler, W.J.9
Pirmohamed, M.10
-
20
-
-
0034529448
-
Immunological principles of adverse drug reactions: The initiation and propagation of immune responses elicited by drug treatment
-
Naisbitt DJ, Gordon SF, Pirmohamed M, and Park BK (2000) Immunological principles of adverse drug reactions: the initiation and propagation of immune responses elicited by drug treatment. Drug Saf 23:483-507.
-
(2000)
Drug Saf
, vol.23
, pp. 483-507
-
-
Naisbitt, D.J.1
Gordon, S.F.2
Pirmohamed, M.3
Park, B.K.4
-
22
-
-
0035793402
-
Predictive drug allergy testing: An alternative viewpoint
-
Pichler WJ (2001) Predictive drug allergy testing: an alternative viewpoint. Toxicology 158:31-41.
-
(2001)
Toxicology
, vol.158
, pp. 31-41
-
-
Pichler, W.J.1
-
23
-
-
0036676978
-
Pharmacological interaction of drugs with antigen-specific immune receptors: The p-i concept
-
Pichler WJ (2002) Pharmacological interaction of drugs with antigen-specific immune receptors: the p-i concept. Curr Opin Allergy Clin Immunol 2:301-305.
-
(2002)
Curr Opin Allergy Clin Immunol
, vol.2
, pp. 301-305
-
-
Pichler, W.J.1
-
24
-
-
0142087834
-
Delayed drug hypersensitivity reactions
-
Pichler WJ (2003) Delayed drug hypersensitivity reactions. Ann Intern Med 139:683-693.
-
(2003)
Ann Intern Med
, vol.139
, pp. 683-693
-
-
Pichler, W.J.1
-
25
-
-
17644416780
-
Direct T-cell stimulations by drugs-bypassing the innate immune system
-
Pichler WJ (2005) Direct T-cell stimulations by drugs-bypassing the innate immune system. Toxicology 209:95-100.
-
(2005)
Toxicology
, vol.209
, pp. 95-100
-
-
Pichler, W.J.1
-
26
-
-
0028077408
-
Severe adverse cutaneous reactions to drugs
-
Roujeau JC and Stern RS (1994) Severe adverse cutaneous reactions to drugs. N Engl J Med 331:1272-1285.
-
(1994)
N Engl J Med
, vol.331
, pp. 1272-1285
-
-
Roujeau, J.C.1
Stern, R.S.2
-
27
-
-
33645034953
-
T cell-mediated hypersensitivity to quinolones: Mechanisms and cross-reactivity
-
Schmid DA, Depta JPH, and Pichler WJ (2006) T cell-mediated hypersensitivity to quinolones: mechanisms and cross-reactivity. Clin Exp Allergy 36:59-69.
-
(2006)
Clin Exp Allergy
, vol.36
, pp. 59-69
-
-
Schmid, D.A.1
Depta, J.P.H.2
Pichler, W.J.3
-
28
-
-
0034660184
-
Recognition of sulfamethoxazole and its reactive metabolites by drug-specific CD4+ T cells from allergic individuals
-
Schnyder B, Burkhart C, Schnyder-Frutig K, von Greyerz S, Naisbitt DJ, Pirmohamed M, Park BK, and Pichler WJ (2000) Recognition of sulfamethoxazole and its reactive metabolites by drug-specific CD4+ T cells from allergic individuals. J Immunol 164:6647-6654.
-
(2000)
J Immunol
, vol.164
, pp. 6647-6654
-
-
Schnyder, B.1
Burkhart, C.2
Schnyder-Frutig, K.3
Von Greyerz, S.4
Naisbitt, D.J.5
Pirmohamed, M.6
Park, B.K.7
Pichler, W.J.8
-
29
-
-
0030822702
-
Direct, MHC-dependent presentation of the drug sulfamethoxazole to human alphabeta T cell clones
-
Schnyder B, Mauri-Hellweg D, Zanni M, Bettens F, and Pichler WJ (1997) Direct, MHC-dependent presentation of the drug sulfamethoxazole to human alphabeta T cell clones. J Clin Investig 100:136-141.
-
(1997)
J Clin Investig
, vol.100
, pp. 136-141
-
-
Schnyder, B.1
Mauri-Hellweg, D.2
Zanni, M.3
Bettens, F.4
Pichler, W.J.5
-
30
-
-
0020601431
-
Antigen recognition by H-2-restricted T cells. I. Cell-free antigen processing
-
Shimonkevitz R, Kappler J, Marrack P, and Grey H (1983) Antigen recognition by H-2-restricted T cells. I. Cell-free antigen processing. J Exp Med 158:303-316.
-
(1983)
J Exp Med
, vol.158
, pp. 303-316
-
-
Shimonkevitz, R.1
Kappler, J.2
Marrack, P.3
Grey, H.4
-
31
-
-
0036279452
-
Delayed-type hypersensitivity reaction to paraphenylenediamine is mediated by 2 different pathways of antigen recognition by specific alphabeta human T-cell clones
-
Sieben S, Kawakubo Y, Al Masaoudi T, Merk HF, and Blomeke B (2002) Delayed-type hypersensitivity reaction to paraphenylenediamine is mediated by 2 different pathways of antigen recognition by specific alphabeta human T-cell clones. J Allergy Clin Immunol 109:1005-1011.
-
(2002)
J Allergy Clin Immunol
, vol.109
, pp. 1005-1011
-
-
Sieben, S.1
Kawakubo, Y.2
Al Masaoudi, T.3
Merk, H.F.4
Blomeke, B.5
-
32
-
-
0033505138
-
Functional expression and analysis of a human HLA-DQ restricted, nickel-reactive T cell receptor in mouse hybridoma cells
-
Vollmer J, Weltzien HU, Dormoy A, Pistoor F, and Moulon C (1999) Functional expression and analysis of a human HLA-DQ restricted, nickel-reactive T cell receptor in mouse hybridoma cells. J Investig Dermatol 113:175-181.
-
(1999)
J Investig Dermatol
, vol.113
, pp. 175-181
-
-
Vollmer, J.1
Weltzien, H.U.2
Dormoy, A.3
Pistoor, F.4
Moulon, C.5
-
33
-
-
0034523151
-
Antigen contacts by Ni-reactive TCR: Typical alphass chain cooperation versus alpha chain-dominated specificity
-
Vollmer J, Weltzien HU, Gamerdinger K, Lang S, Choleva Y, and Moulon C (2000) Antigen contacts by Ni-reactive TCR: typical alphass chain cooperation versus alpha chain-dominated specificity. Int Immunol 12:1723-1731.
-
(2000)
Int Immunol
, vol.12
, pp. 1723-1731
-
-
Vollmer, J.1
Weltzien, H.U.2
Gamerdinger, K.3
Lang, S.4
Choleva, Y.5
Moulon, C.6
-
34
-
-
0034926089
-
Degeneracy and additional alloreactivity of drug-specific human alpha beta(+) T cell clones
-
von Greyerz S, Bultemann G, Schnyder K, Burkhart C, Lotti B, Hari Y, and Pichler WJ (2001) Degeneracy and additional alloreactivity of drug-specific human alpha beta(+) T cell clones. Int Immunol 13:877-885.
-
(2001)
Int Immunol
, vol.13
, pp. 877-885
-
-
Von Greyerz, S.1
Bultemann, G.2
Schnyder, K.3
Burkhart, C.4
Lotti, B.5
Hari, Y.6
Pichler, W.J.7
-
35
-
-
0032960782
-
Interaction of sulfonamide derivatives with the TCR of sulfamethoxazole-specific human ab+ T cell clones
-
von Greyerz S, Zanni MP, Frutig K, Schnyder B, Burkhart C, and Pichler WJ (1999) Interaction of sulfonamide derivatives with the TCR of sulfamethoxazole-specific human ab+ T cell clones. J Immunol 162:595-602.
-
(1999)
J Immunol
, vol.162
, pp. 595-602
-
-
Von Greyerz, S.1
Zanni, M.P.2
Frutig, K.3
Schnyder, B.4
Burkhart, C.5
Pichler, W.J.6
-
36
-
-
0027434907
-
Antigen-presenting human T cells and antigen-presenting B cells induce a similar cytokine profile in specific T cell clones
-
Wyss-Coray T, Gallati H, Pracht I, Limat A, Mauri D, Frutig K, and Pichler WJ (1993) Antigen-presenting human T cells and antigen-presenting B cells induce a similar cytokine profile in specific T cell clones. Eur J Immunol 23:3350-3357.
-
(1993)
Eur J Immunol
, vol.23
, pp. 3350-3357
-
-
Wyss-Coray, T.1
Gallati, H.2
Pracht, I.3
Limat, A.4
Mauri, D.5
Frutig, K.6
Pichler, W.J.7
-
37
-
-
0033774505
-
T cells isolated from positive epicutaneous test reactions to amoxicillin and ceftriaxone are drug specific and cytotoxic
-
Yawalkar N, Hari Y, Frutig K, Egli F, Wendland T, Braathen LR, and Pichler WJ (2000) T cells isolated from positive epicutaneous test reactions to amoxicillin and ceftriaxone are drug specific and cytotoxic. J Investig Dermatol 115:647-652.
-
(2000)
J Investig Dermatol
, vol.115
, pp. 647-652
-
-
Yawalkar, N.1
Hari, Y.2
Frutig, K.3
Egli, F.4
Wendland, T.5
Braathen, L.R.6
Pichler, W.J.7
-
38
-
-
0031066617
-
Characterization of lidocaine-specific T cells
-
Zanni MP, Mauri-Hellweg D, Brander C, Wendland T, Schnyder B, Frei E, von Greyerz S, Bircher A, and Pichler WJ (1997) Characterization of lidocaine-specific T cells. J Immunol 158:1139-1148.
-
(1997)
J Immunol
, vol.158
, pp. 1139-1148
-
-
Zanni, M.P.1
Mauri-Hellweg, D.2
Brander, C.3
Wendland, T.4
Schnyder, B.5
Frei, E.6
Von Greyerz, S.7
Bircher, A.8
Pichler, W.J.9
-
39
-
-
0032532378
-
HLA-restricted, processing- and metabolism-independent pathway of drug recognition by human alpha beta T lymphocytes
-
Zanni MP, von Greyerz S, Schnyder B, Brander KA, Frutig K, Hari Y, Valitutti S, and Pichler WJ (1998a) HLA-restricted, processing- and metabolism-independent pathway of drug recognition by human alpha beta T lymphocytes. J Clin Investig 102:1591-1598.
-
(1998)
J Clin Investig
, vol.102
, pp. 1591-1598
-
-
Zanni, M.P.1
Von Greyerz, S.2
Schnyder, B.3
Brander, K.A.4
Frutig, K.5
Hari, Y.6
Valitutti, S.7
Pichler, W.J.8
-
40
-
-
0031896946
-
Allele-unrestricted presentation of lidocaine by HLA-DR molecules to specific ab+ T cell clones
-
Zanni MP, von Greyerz S, Schnyder B, Wendland T, and Pichler WJ (1998b) Allele-unrestricted presentation of lidocaine by HLA-DR molecules to specific ab+ T cell clones. Int Immunol 10:507-515.
-
(1998)
Int Immunol
, vol.10
, pp. 507-515
-
-
Zanni, M.P.1
Von Greyerz, S.2
Schnyder, B.3
Wendland, T.4
Pichler, W.J.5
|