The discodermolide hairpin structure flows from conformationally stable modular motifs

Journal of Medicinal Chemistry

Volumn 53, Issue 1, 2010, Pages 155-165

  Jogalekar, Ashutosh S ^a   Kriel, Frederik H ^a   Shi, Qi ^a   Cornett, Ben ^a   Cicero, Daniel ^b   Snyder, James P ^a  

^a EMORY UNIVERSITY   (United States)

^b UNIVERSITY OF ROME TOR VERGATA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BETA TUBULIN; DISCODERMOLIDE;

ARTICLE; BINDING KINETICS; CONFORMATIONAL TRANSITION; DENSITY FUNCTIONAL THEORY; DRUG CONFORMATION; LIGAND BINDING; MOLECULAR DOCKING; MOLECULAR STABILITY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; STRUCTURE ACTIVITY RELATION;

ALKANES; AMINO ACID MOTIFS; ANIMALS; CARBAMATES; COMPUTER SIMULATION; CRYSTALLOGRAPHY, X-RAY; LACTONES; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, CHEMICAL; MODELS, MOLECULAR; MOLECULAR CONFORMATION; PORIFERA; PYRONES; QUANTUM THEORY; STRUCTURE-ACTIVITY RELATIONSHIP; TUBULIN;

EID: 74849140127     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9015284     Document Type: Article

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