Total synthesis of discodermolide: Optimization of the effective synthetic route

Chemistry - A European Journal

Volumn 14, Issue 35, 2008, Pages 11092-11112

  De Lemos, Elsa ^a   Porée, François Hugues ^a   Bourin, Arnaud ^a   Barbion, Julien ^a   Agouridas, Evangelos ^a   Lannou, Marie Isabelle ^a   Commerçon, Alain ^b   Betzer, Jean François ^a   Pancrazi, Ange ^a   Ardisson, Janick ^a  

^a UNIVERSITÉ PARIS DESCARTES   (France)

^b SANOFI   (France)

Author keywords

Allylation; Cross coupling; Discodermolide; Nickel; Total synthesis

Indexed keywords

POLYMERS;

ALLYLATION; CROSS-COUPLING; DISCODERMOLIDE; DOUBLE BONDS; POLYKETIDE; REPEATED APPLICATIONS; SEQUENTIAL STAGES; STRUCTURAL ANALOGUES; STRUCTURAL VARIATIONS; SYNTHETIC APPROACHES; SYNTHETIC ROUTES; TOTAL SYNTHESES; TOTAL SYNTHESIS;

OPTIMIZATION;

ALCOHOL DERIVATIVE; ALKANE; ALKENE; ANTINEOPLASTIC AGENT; CARBAMIC ACID DERIVATIVE; DISCODERMOLIDE; LACTONE; PYRONE DERIVATIVE; TUBULIN MODULATOR;

ARTICLE; SYNTHESIS;

ALCOHOLS; ALKANES; ALKENES; ANTINEOPLASTIC AGENTS; CARBAMATES; LACTONES; PYRONES; TUBULIN MODULATORS;

EID: 57149145926     PISSN: 09476539     EISSN: 15213765     Source Type: Journal    
DOI: 10.1002/chem.200801478     Document Type: Article

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