A highly epothilone B-resistant A549 cell line with mutations in tubulin that confer drug dependence

Molecular Cancer Therapeutics

Volumn 4, Issue 6, 2005, Pages 987-995

  Yang, Chia Ping Huang ^a   Verdier Pinard, Pascal ^a   Wang, Fang ^a   Lippaine Horvath, Eva ^a   He, Lifeng ^a   Li, Dansu ^b   Höfle, Gerhard ^c   Ojima, Iwao ^b   Orr, George A ^a   Horwitz, Susan Band ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b STONY BROOK UNIVERSITY   (United States)

^c HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TUBULIN; BETA TUBULIN; EPOTHILONE B; GLUTAMIC ACID; GLYCINE; LEUCINE; METHIONINE; MICROTUBULE ASSOCIATED PROTEIN 4; PACLITAXEL; PHENYLALANINE; REGULATOR PROTEIN; STATHMIN; TUBULIN; VALINE; VINBLASTINE;

AMINO ACID SUBSTITUTION; ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CANCER RESISTANCE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CROSS RESISTANCE; DRUG EFFICACY; DRUG SENSITIVITY; GENE MUTATION; GENE SEQUENCE; HUMAN; HUMAN CELL; LUNG CARCINOMA; MASS SPECTROMETRY; MICROTUBULE; MOLECULAR MODEL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION;

CELL LINE, TUMOR; CELL PROLIFERATION; DIMERIZATION; DRUG RESISTANCE, NEOPLASM; EPOTHILONES; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INHIBITORY CONCENTRATION 50; MICROTUBULE PROTEINS; MODELS, MOLECULAR; MUTATION; PACLITAXEL; PHOSPHOPROTEINS; PROTEIN STRUCTURE, QUATERNARY; STATHMIN; TUBULIN;

EID: 21344471145     PISSN: 15357163     EISSN: None     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-05-0024     Document Type: Article

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