Conformation-activity relationships in polyketide natural products. Towards the biologically active conformation of epothilone

Organic and Biomolecular Chemistry

Volumn 2, Issue 1, 2004, Pages 127-132

  Taylor, Richard E ^a   Chen, Yue ^a,b   Galvin, Gabriel M ^a,c   Pabba, Praveen K ^a,d  

^a UNIVERSITY OF NOTRE DAME   (United States)

^b KOSAN BIOSCIENCES INC   (United States)

^c BRISTOL MYERS SQUIBB COMPANY   (United States)

^d LEXICON PHARMACEUTICALS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONFORMATIONS; MOLECULAR DYNAMICS; MOLECULAR STRUCTURE; MONTE CARLO METHODS; NUCLEAR MAGNETIC RESONANCE; SOLUTIONS; SYNTHESIS (CHEMICAL);

BIOLOGICAL ASSAYS; CONFORMERS; EPOTHILONE; POLYKETIDE; POLYPROPIONATE;

ORGANIC COMPOUNDS;

EPOTHILONE DERIVATIVE;

ARTICLE; CHEMISTRY; CONFORMATION; DRUG DESIGN; STRUCTURE ACTIVITY RELATION;

DRUG DESIGN; EPOTHILONES; MOLECULAR CONFORMATION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 1642420641     PISSN: 14770520     EISSN: None     Source Type: Journal    
DOI: 10.1039/b312213c     Document Type: Article

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