Conformational preferences of natural and C3-modified epothilones in aqueous solution

Journal of Medicinal Chemistry

Volumn 51, Issue 5, 2008, Pages 1469-1473

  Erdélyi, Máté ^a   Pfeiffer, Bernhard ^b   Hauenstein, Kurt ^b   Fohrer, Jörg ^a   Gertsch, Jürg ^b   Altmann, Karl Heinz ^b   Carlomagno, Teresa ^a,c  

^a MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

^b ETH ZURICH   (Switzerland)

^c EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

EPOTHILONE A; EPOTHILONE DERIVATIVE;

AB INITIO CALCULATION; AQUEOUS SOLUTION; ARTICLE; CONTROLLED STUDY; DRUG CONFORMATION; DRUG STRUCTURE; HUMAN; HUMAN CELL; MONTE CARLO METHOD; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; STRUCTURE ACTIVITY RELATION;

EPOTHILONES; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MONTE CARLO METHOD; SOLUTIONS; TUBULIN; WATER;

EID: 41649104278     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm7013452     Document Type: Article

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