Aryloxy phosphoramidate triesters: A technology for delivering monophosphorylated nucleosides and sugars into cells

ChemMedChem

Volumn 4, Issue 11, 2009, Pages 1779-1791

  Mehellou, Youcef ^a   Balzarini, Jan ^b   McGuigan, Christopher ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

Drug delivery; Nucleosides; Nucleotides; Phosphoramidates; Prodrugs

Indexed keywords

4' AZIDOCYTIDINE; 4' AZIDOURIDINE; 5 (2 BROMOVINYL) 2' DEOXYURIDINE; ABACAVIR; ADEFOVIR; ADENALLENE; ALKANEDIOL DERIVATIVE; ANTINEOPLASTIC AGENT; ANTIVIRUS AGENT; CARBOHYDRATE DERIVATIVE; CYTARABINE; ESTER DERIVATIVE; GLUCOSAMINE; GLUCOSAMINE DERIVATIVE; GS 7340; GS 9131; LAMIVUDINE; N ACETYLGLUCOSAMINE; NB 1011; NUCLEOSIDE DERIVATIVE; PHOSPHORAMIDIC ACID DERIVATIVE; PHOSPHORODIAMIDATE DERIVATIVE; RIBONUCLEOSIDE DERIVATIVE; STAMPIDINE; STAVUDINE; TENOFOVIR; THYMECTACIN; UNCLASSIFIED DRUG; UNINDEXED DRUG; VIDARABINE; ZALCITABINE; ZIDOVUDINE;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ANTINEOPLASTIC ACTIVITY; ANTIVIRAL ACTIVITY; CELL MEMBRANE PERMEABILITY; CLINICAL TRIAL; COLON CANCER; DRUG DELIVERY SYSTEM; DRUG MECHANISM; DRUG RELEASE; DRUG SYNTHESIS; HALOGENATION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; NONHUMAN; OSTEOARTHRITIS; PHOSPHORYLATION; PRIORITY JOURNAL; SHORT SURVEY; STRUCTURE ACTIVITY RELATION;

AMIDES; ANTI-HIV AGENTS; ANTINEOPLASTIC AGENTS; ANTIVIRAL AGENTS; CARBOHYDRATES; CELL LINE, TUMOR; DRUG CARRIERS; HUMANS; NUCLEOSIDES; PHOSPHORIC ACIDS;

EID: 73449119606     PISSN: 18607179     EISSN: 18607187     Source Type: Journal    
DOI: 10.1002/cmdc.200900289     Document Type: Short Survey

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