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Volumn 43, Issue 6, 1999, Pages 1487-1490

In vitro anti-human immunodeficiency virus activities of Z- and E- methylenecyclopropane nucleoside analogues and their phosphoro-L-alaninate diesters

Author keywords

[No Author keywords available]

Indexed keywords

2',3' DIDEOXYNUCLEOSIDE DERIVATIVE; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; CYCLOPROPANE DERIVATIVE; DIDANOSINE; ESTER DERIVATIVE; NUCLEOSIDE ANALOG; QYL 609; QYL 685; UNCLASSIFIED DRUG; ZIDOVUDINE;

EID: 0033026673     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.43.6.1487     Document Type: Article
Times cited : (33)

References (27)
  • 1
    • 0021814903 scopus 로고
    • Synthesis and antiherpetic activity of (S)-, (R)-, and (+/-)-9-[(2,3-dihydroxy-1-propoxy)methyl]guanine, linear isomers of 2′-nor-2′-deoxyguanosine
    • Ashton, W. T., L. F. Canning, G. F. Reynolds, R. L. Tolman, J. D. Karkas, R. Liou, M. E. Davies, C. M. DeWitt, H. C. Perry, and A. K. Field. 1985. Synthesis and antiherpetic activity of (S)-, (R)-, and (+/-)-9-[(2,3-dihydroxy-1-propoxy)methyl]guanine, linear isomers of 2′-nor-2′-deoxyguanosine. J. Med. Chem. 28:925-933.
    • (1985) J. Med. Chem. , vol.28 , pp. 925-933
    • Ashton, W.T.1    Canning, L.F.2    Reynolds, G.F.3    Tolman, R.L.4    Karkas, J.D.5    Liou, R.6    Davies, M.E.7    Dewitt, C.M.8    Perry, H.C.9    Field, A.K.10
  • 6
    • 0032485470 scopus 로고    scopus 로고
    • 9-Hydroxymethyl-cyclopropylidenemethylenyladenine: The design, facile synthesis, isomer separation and anti-HIV-1 activities
    • Cheng, C., T. Shimo, K. Somekawa, and M. Baba. 1998. 9-Hydroxymethyl-cyclopropylidenemethylenyladenine: the design, facile synthesis, isomer separation and anti-HIV-1 activities. Tetrahedron 54:2031-2040.
    • (1998) Tetrahedron , vol.54 , pp. 2031-2040
    • Cheng, C.1    Shimo, T.2    Somekawa, K.3    Baba, M.4
  • 9
    • 0028120730 scopus 로고
    • HIV resistance to reverse transcriptase inhibitors
    • De Clercq, E. 1994. HIV resistance to reverse transcriptase inhibitors. Biochem. Pharmacol. 47:155-169.
    • (1994) Biochem. Pharmacol. , vol.47 , pp. 155-169
    • De Clercq, E.1
  • 10
    • 0030708683 scopus 로고    scopus 로고
    • In search of a selective antiviral chemotherapy
    • De Clercq, E. 1997. In search of a selective antiviral chemotherapy. Clin. Microbiol. Rev. 10:674-693.
    • (1997) Clin. Microbiol. Rev. , vol.10 , pp. 674-693
    • De Clercq, E.1
  • 12
    • 0007621056 scopus 로고
    • Adenallene and cytallene: Acyclic nucleosides that inhibit replication and cytopathic effect of human immunodeficiency virus (HIV) in vitro
    • Hayashi, S., S. Phadtare, J. Zemlicka, M. Matsukura, H. Mitsuya, and S. Broder. 1988. Adenallene and cytallene: acyclic nucleosides that inhibit replication and cytopathic effect of human immunodeficiency virus (HIV) in vitro. Proc. Natl. Acad. Sci. USA 85:6127-6131.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 6127-6131
    • Hayashi, S.1    Phadtare, S.2    Zemlicka, J.3    Matsukura, M.4    Mitsuya, H.5    Broder, S.6
  • 13
    • 0030199967 scopus 로고    scopus 로고
    • Application of a gastric cancer cell line (MKN-28) for anti-adenovirus screening using the MTT method
    • Kodama, E., S. Shigeta, T. Suzuki, and E. De Clercq. 1996. Application of a gastric cancer cell line (MKN-28) for anti-adenovirus screening using the MTT method. Antivir. Res. 31:159-164.
    • (1996) Antivir. Res. , vol.31 , pp. 159-164
    • Kodama, E.1    Shigeta, S.2    Suzuki, T.3    De Clercq, E.4
  • 15
    • 0345002794 scopus 로고    scopus 로고
    • Nucleoside analogues and their antiretroviral activity
    • H. Mitsuya (ed.), R. G. Langes Company, Austin, Tex
    • Mitsuya, H. 1997. Nucleoside analogues and their antiretroviral activity, p. 3-22. In H. Mitsuya (ed.), Anti-HIV nucleosides: past, present and future. R. G. Langes Company, Austin, Tex.
    • (1997) Anti-HIV Nucleosides: Past, Present and Future , pp. 3-22
    • Mitsuya, H.1
  • 16
    • 0002052695 scopus 로고    scopus 로고
    • Discovery and development of antiretroviral therapeutics for HIV infection
    • T. C. Merigan (ed.), Williams & Wilkins, Baltimore, Md
    • Mitsuya, H., and J. Erickson. 1998. Discovery and development of antiretroviral therapeutics for HIV infection, p. 751-780. In T. C. Merigan (ed.), Textbook of AIDS medicine, Williams & Wilkins, Baltimore, Md.
    • (1998) Textbook of AIDS Medicine , pp. 751-780
    • Mitsuya, H.1    Erickson, J.2
  • 19
  • 22
    • 0011129306 scopus 로고
    • In vitro evaluation of experimental agents for anti-HIV activity
    • J. E. Coligan, A. M. Kruisbeek, D. H. Margulies, E. M. Shevach, and W. Strober, John Wiley & Sons, Inc., New York, N.Y.
    • Richman, D. D., V. A. Johnson, D. L. Mayers, T. Shirasaka, M. C. O'Brien, and H. Mitsuya. 1993. In vitro evaluation of experimental agents for anti-HIV activity, p. 12.9.1-12.9.21. In J. E. Coligan, A. M. Kruisbeek, D. H. Margulies, E. M. Shevach, and W. Strober, Current protocols in immunology. John Wiley & Sons, Inc., New York, N.Y.
    • (1993) Current Protocols in Immunology , pp. 1291-12921
    • Richman, D.D.1    Johnson, V.A.2    Mayers, D.L.3    Shirasaka, T.4    O'Brien, M.C.5    Mitsuya, H.6
  • 23
    • 0028823560 scopus 로고
    • Comparative analysis of anti-human immunodeficiency virus type 1 activities of dideoxynucleoside analogs in resting and activated peripheral blood mononuclear cells
    • Shirasaka, T., S. Chokekijchai, A. Yamada, G. Gosselin, J.-L. Imbach, and H. Mitsuya. 1995. Comparative analysis of anti-human immunodeficiency virus type 1 activities of dideoxynucleoside analogs in resting and activated peripheral blood mononuclear cells. Antimicrob. Agents Chemother. 39: 2555-2559.
    • (1995) Antimicrob. Agents Chemother. , vol.39 , pp. 2555-2559
    • Shirasaka, T.1    Chokekijchai, S.2    Yamada, A.3    Gosselin, G.4    Imbach, J.-L.5    Mitsuya, H.6
  • 25
    • 0027398296 scopus 로고
    • Changes in drug sensitivity of human immunodeficiency virus type 1 during therapy with azidothymidine, dideoxycytidine, and dideoxyinosine: An in vitro comparative study
    • Shirasaka, T., R. Yarchoan, M. C. O'Brien, R. N. Husson, B. D. Anderson, E. Kojima, T. Shimada, S. Broder, and H. Mitsuya. 1993. Changes in drug sensitivity of human immunodeficiency virus type 1 during therapy with azidothymidine, dideoxycytidine, and dideoxyinosine: an in vitro comparative study. Proc. Natl. Acad. Sci. USA 90:562-566.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 562-566
    • Shirasaka, T.1    Yarchoan, R.2    O'Brien, M.C.3    Husson, R.N.4    Anderson, B.D.5    Kojima, E.6    Shimada, T.7    Broder, S.8    Mitsuya, H.9
  • 26
    • 0025770237 scopus 로고
    • Specific anti-HIV-1 "acyclonucleosides" which cannot be phosphorylated: Synthesis of some deoxy analogues of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine
    • Tanaka, H., M. Baba, S. Saito, T. Miyasaka, H. Takasha, K. Sekiya, M. Ubasawa, I. Nitta, R. T. Walker, H. Nakashima, and E. De Clercq. 1991. Specific anti-HIV-1 "acyclonucleosides" which cannot be phosphorylated: synthesis of some deoxy analogues of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine. J. Med. Chem. 34:1508-1511.
    • (1991) J. Med. Chem. , vol.34 , pp. 1508-1511
    • Tanaka, H.1    Baba, M.2    Saito, S.3    Miyasaka, T.4    Takasha, H.5    Sekiya, K.6    Ubasawa, M.7    Nitta, I.8    Walker, R.T.9    Nakashima, H.10    De Clercq, E.11
  • 27
    • 0031009294 scopus 로고    scopus 로고
    • In vitro induction of human immunodeficiency virus type 1 (HIV-1) variants resistant to 2′-β-fluoro-2′,3′-dideoxyadenosine (F-ddA)
    • Tanaka, M., R. V. Srinivas, T. Ueno, M. F. Kavlick, F. K. Hui, A. Fridland, J. S. Driscoll, and H. Mitsuya. 1997. In vitro induction of human immunodeficiency virus type 1 (HIV-1) variants resistant to 2′-β-fluoro-2′,3′-dideoxyadenosine (F-ddA). Antimicrob. Agents Chemother. 41:1313-1318.
    • (1997) Antimicrob. Agents Chemother. , vol.41 , pp. 1313-1318
    • Tanaka, M.1    Srinivas, R.V.2    Ueno, T.3    Kavlick, M.F.4    Hui, F.K.5    Fridland, A.6    Driscoll, J.S.7    Mitsuya, H.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.