Synthesis and antiviral activity of phosphoralaninate derivatives of methylenecyclopropane analogues of nucleosides

Antiviral Research

Volumn 43, Issue 1, 1999, Pages 37-53

  Qiu, Yao Ling ^a   Ptak, Roger G ^b   Breitenbach, Julie M ^b   Lin, Ju Sheng ^c   Cheng, Yung Chi ^c   Drach, John C ^b   Kern, Earl R ^d   Zemlicka, Jiri ^a  

^a Department of Chemistry   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d University of Alabama at Birmingham   (United States)

Author keywords

Antivirals; EBV; HBV; HCMV; HHV 6; HIV 1; HSV 1; HSV 2; MCMV; Methylenecyclopropane analogues; Phenyl phosphoralaninates; Prodrugs; VZV

Indexed keywords

NUCLEOSIDE ANALOG; PHOSPHORALANINATE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOMEGALOVIRUS; CYTOTOXICITY; DRUG POTENCY; DRUG SYNTHESIS; EPSTEIN BARR VIRUS; HEPATITIS B VIRUS; HERPES SIMPLEX VIRUS; HERPES VIRUS; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; VARICELLA ZOSTER VIRUS;

ALANINE; ANTI-HIV AGENTS; ANTIVIRAL AGENTS; CYCLOPROPANES; HEPATITIS B VIRUS; HERPESVIRIDAE; HIV-1; HUMANS; PRODRUGS;

EID: 0032802987     PISSN: 01663542     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-3542(99)00029-7     Document Type: Article

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