Decomposition pathways and in vitro HIV inhibitory effects of isoddA pronucleotides: Toward a rational approach for intracellular delivery of nucleoside 5′-monophosphates

Journal of Medicinal Chemistry

Volumn 39, Issue 10, 1996, Pages 1981-1990

  Valette, Gilles ^a   Pompon, Alain ^a   Girardet, Jean Luc ^a   Cappellacci, Loredana ^b   Franchetti, Palmarisa ^b   Grifantini, Mario ^b   La Colla, Paolo ^c   Loi, Anna Giulia ^c   Périgaud, Christian ^a   Gosselin, Gilles ^a   Imbach, Jean Louis ^a  

^a CNRS   (France)

^b UNIVERSITY OF CAMERINO   (Italy)

^c UNIVERSITY OF CAGLIARI   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; ISODIDEOXYADENOSINE 5' (METHOXYALANINYLPHOSPHORAMIDATE) TRIETHYLAMMONIUM; ISODIDEOXYADENOSINE 5' (PHENYL METHOXYALANYLPHOSPHATE); NUCLEOSIDE ANALOG; PHOSPHORAMIDIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; DRUG DECOMPOSITION; DRUG MECHANISM; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 2; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; KINETICS; STRUCTURE ACTIVITY RELATION; VIRUS INHIBITION;

CELL LINE; DIDEOXYADENOSINE; HIV-1; HIV-2; HUMANS; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; NUCLEOTIDES; SPECTROMETRY, MASS, FAST ATOM BOMBARDMENT;

EID: 0029953984     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9507338     Document Type: Article

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