Phosphodiester amidates of allenic nucleoside analogues: Anti-HIV activity and possible mechanism of action

Journal of Medicinal Chemistry

Volumn 39, Issue 17, 1996, Pages 3300-3306

  Winter, Holger ^b   Maeda, Yosuke ^c   Mitsuya, Hiroaki ^c   Zemlicka, Jiri ^a,b  

^a KARMANOS CANCER INSTITUTE   (United States)

^b WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENALLENE; ANTIVIRUS AGENT; DIDANOSINE; NUCLEOSIDE DERIVATIVE; ZIDOVUDINE;

ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFICACY; DRUG HYDROLYSIS; DRUG MECHANISM; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LIPOPHILICITY; VIRUS INHIBITION;

ADENOSINE MONOPHOSPHATE; ALKADIENES; ANIMALS; ANTIVIRAL AGENTS; CELL LINE; ESTERASES; HIV-1; HUMANS; HYDROLYSIS; KINETICS; LIVER; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; PHOSPHORIC DIESTER HYDROLASES; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; SWINE; THYMIDINE MONOPHOSPHATE; VIRUS REPLICATION;

EID: 0029784856     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm960330n     Document Type: Article

References (41)

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