메뉴 건너뛰기




Volumn 31, Issue 1, 2010, Pages 110-118

Genetic reductions of β-site amyloid precursor protein-cleaving enzyme 1 and amyloid-β ameliorate impairment of conditioned taste aversion memory in 5XFAD Alzheimer's disease model mice

Author keywords

secretase; APP transgenic; BACE1; Implicit memory; Knockout

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; BETA SECRETASE; BETA SECRETASE 1; PRESENILIN 1;

EID: 72949094212     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2009.07031.x     Document Type: Article
Times cited : (72)

References (49)
  • 1
    • 0035674312 scopus 로고    scopus 로고
    • Learning and memory in transgenic mice modeling Alzheimer's disease
    • Ashe, K.H. (2001) Learning and memory in transgenic mice modeling Alzheimer's disease. Learn. Mem., 8, 301 308.
    • (2001) Learn. Mem. , vol.8 , pp. 301-308
    • Ashe, K.H.1
  • 2
    • 0033586449 scopus 로고    scopus 로고
    • Impairments in learning and memory accompanied by neurodegeneration in mice transgenic for the carboxyl-terminus of the amyloid precursor protein
    • Berger-Sweeney, J., McPhie, D.L., Arters, J.A., Greenan, J., Oster-Granite, M.L. Neve, R.L. (1999) Impairments in learning and memory accompanied by neurodegeneration in mice transgenic for the carboxyl-terminus of the amyloid precursor protein. Brain Res. Mol. Brain Res., 66, 150 162.
    • (1999) Brain Res. Mol. Brain Res. , vol.66 , pp. 150-162
    • Berger-Sweeney, J.1    McPhie, D.L.2    Arters, J.A.3    Greenan, J.4    Oster-Granite, M.L.5    Neve, R.L.6
  • 3
    • 1342268181 scopus 로고    scopus 로고
    • Molecular mechanisms of taste-recognition memory
    • Bermudez-Rattoni, F. (2004) Molecular mechanisms of taste-recognition memory. Nat. Rev. Neurosci., 5, 209 217.
    • (2004) Nat. Rev. Neurosci. , vol.5 , pp. 209-217
    • Bermudez-Rattoni, F.1
  • 5
    • 0027104098 scopus 로고
    • Memory deficits in Alzheimer's patients: A comprehensive review
    • Carlesimo, G.A. Oscar-Berman, M. (1992) Memory deficits in Alzheimer's patients: a comprehensive review. Neuropsychol. Rev., 3, 119 169.
    • (1992) Neuropsychol. Rev. , vol.3 , pp. 119-169
    • Carlesimo, G.A.1    Oscar-Berman, M.2
  • 6
    • 35248882587 scopus 로고    scopus 로고
    • Amyloid-beta reduction by memapsin 2 (beta-secretase) immunization
    • DOI 10.1096/fj.06-7993com
    • Chang, W.P., Downs, D., Huang, X.P., Da, H., Fung, K.M. Tang, J. (2007) Amyloid-β reduction by memapsin 2 (β-secretase) immunization. FASEB J., 21, 3184 3196. (Pubitemid 47565537)
    • (2007) FASEB Journal , vol.21 , Issue.12 , pp. 3184-3196
    • Chang, W.-P.1    Downs, D.2    Huang, X.-P.3    Da, H.4    Fung, K.-M.5    Tang, J.6
  • 7
    • 0035432158 scopus 로고    scopus 로고
    • Memory impairment and cholinergic dysfunction by centrally administered Aβ and carboxyl-terminal fragment of Alzheimer's APP in mice
    • Choi, S.H., Park, C.H., Koo, J.W., Seo, J.H., Kim, H.S., Jeong, S.J., Lee, J.H., Kim, S.S. Suh, Y.H. (2001) Memory impairment and cholinergic dysfunction by centrally administered Aβ and carboxyl-terminal fragment of Alzheimer's APP in mice. FASEB J., 15, 1816 1818.
    • (2001) FASEB J. , vol.15 , pp. 1816-1818
    • Choi, S.H.1    Park, C.H.2    Koo, J.W.3    Seo, J.H.4    Kim, H.S.5    Jeong, S.J.6    Lee, J.H.7    Kim, S.S.8    Suh, Y.H.9
  • 8
    • 43049145839 scopus 로고    scopus 로고
    • Inactivation of the anterior cingulate cortex blocks expression of remote, but not recent, conditioned taste aversion memory
    • Ding, H.K., Teixeira, C.M. Frankland, P.W. (2008) Inactivation of the anterior cingulate cortex blocks expression of remote, but not recent, conditioned taste aversion memory. Learn. Mem., 15, 290 293.
    • (2008) Learn. Mem. , vol.15 , pp. 290-293
    • Ding, H.K.1    Teixeira, C.M.2    Frankland, P.W.3
  • 9
    • 33846466652 scopus 로고    scopus 로고
    • Plaques, tangles, and memory loss in mouse models of neurodegeneration
    • Eriksen, J.L. Janus, C.G. (2007) Plaques, tangles, and memory loss in mouse models of neurodegeneration. Behav. Genet., 37, 79 100.
    • (2007) Behav. Genet. , vol.37 , pp. 79-100
    • Eriksen, J.L.1    Janus, C.G.2
  • 10
    • 0034058460 scopus 로고    scopus 로고
    • Contextual fear, gestalt memories, and the hippocampus
    • Fanselow, M.S. (2000) Contextual fear, gestalt memories, and the hippocampus. Behav. Brain Res., 110, 73 81.
    • (2000) Behav. Brain Res. , vol.110 , pp. 73-81
    • Fanselow, M.S.1
  • 13
    • 0036718272 scopus 로고    scopus 로고
    • β-Secretase protein and activity are increased in the neocortex in Alzheimer disease
    • Fukumoto, H., Cheung, B.S., Hyman, B.T. Irizarry, M.C. (2002) β-Secretase protein and activity are increased in the neocortex in Alzheimer disease. Arch. Neurol., 59, 1381 1389.
    • (2002) Arch. Neurol. , vol.59 , pp. 1381-1389
    • Fukumoto, H.1    Cheung, B.S.2    Hyman, B.T.3    Irizarry, M.C.4
  • 14
    • 45749151056 scopus 로고    scopus 로고
    • Animal models of Alzheimer's disease and frontotemporal dementia
    • Gotz, J. Ittner, L.M. (2008) Animal models of Alzheimer's disease and frontotemporal dementia. Nat. Rev. Neurosci., 9, 532 544.
    • (2008) Nat. Rev. Neurosci. , vol.9 , pp. 532-544
    • Gotz, J.1    Ittner, L.M.2
  • 16
    • 0036260892 scopus 로고    scopus 로고
    • Increased expression of the amyloid precursor β-secretase in Alzheimer's disease
    • Holsinger, R.M., McLean, C.A., Beyreuther, K., Masters, C.L. Evin, G. (2002) Increased expression of the amyloid precursor β-secretase in Alzheimer's disease. Ann. Neurol., 51, 783 786.
    • (2002) Ann. Neurol. , vol.51 , pp. 783-786
    • Holsinger, R.M.1    McLean, C.A.2    Beyreuther, K.3    Masters, C.L.4    Evin, G.5
  • 17
    • 4143061218 scopus 로고    scopus 로고
    • Impaired conditioned taste aversion learning in APP transgenic mice
    • DOI 10.1016/j.neurobiolaging.2003.11.007, PII S0197458004000272
    • Janus, C., Welzl, H., Hanna, A., Lovasic, L., Lane, N., St George-Hyslop, P. Westaway, D. (2004) Impaired conditioned taste aversion learning in APP transgenic mice. Neurobiol. Aging, 25, 1213 1219. (Pubitemid 39094024)
    • (2004) Neurobiology of Aging , vol.25 , Issue.9 , pp. 1213-1219
    • Janus, C.1    Welzl, H.2    Hanna, A.3    Lovasic, L.4    Lane, N.5    St. George-Hyslop, P.6    Westaway, D.7
  • 18
    • 0029567045 scopus 로고
    • Implicit memory performance of patients with Alzheimer's disease: A brief review
    • Jelicic, M., Bonebakker, A.E. Bonke, B. (1995) Implicit memory performance of patients with Alzheimer's disease: a brief review. Int. Psychogeriatr., 7, 385 392.
    • (1995) Int. Psychogeriatr. , vol.7 , pp. 385-392
    • Jelicic, M.1    Bonebakker, A.E.2    Bonke, B.3
  • 19
    • 4043105520 scopus 로고    scopus 로고
    • Inducible repression of CREB function disrupts amygdala-dependent memory
    • Josselyn, S.A., Kida, S. Silva, A.J. (2004) Inducible repression of CREB function disrupts amygdala-dependent memory. Neurobiol. Learn. Mem., 82, 159 163.
    • (2004) Neurobiol. Learn. Mem. , vol.82 , pp. 159-163
    • Josselyn, S.A.1    Kida, S.2    Silva, A.J.3
  • 20
    • 58149479368 scopus 로고    scopus 로고
    • Impairments in remote memory stabilization precede hippocampal synaptic and cognitive failures in 5XFAD Alzheimer mouse model
    • Kimura, R. Ohno, M. (2009) Impairments in remote memory stabilization precede hippocampal synaptic and cognitive failures in 5XFAD Alzheimer mouse model. Neurobiol. Dis., 33, 229 235.
    • (2009) Neurobiol. Dis. , vol.33 , pp. 229-235
    • Kimura, R.1    Ohno, M.2
  • 21
    • 17644370721 scopus 로고    scopus 로고
    • Behavioral phenotypes of amyloid-based genetically modified mouse models of Alzheimer's disease
    • Kobayashi, D.T. Chen, K.S. (2005) Behavioral phenotypes of amyloid-based genetically modified mouse models of Alzheimer's disease. Genes Brain Behav., 4, 173 196.
    • (2005) Genes Brain Behav. , vol.4 , pp. 173-196
    • Kobayashi, D.T.1    Chen, K.S.2
  • 22
    • 17044439021 scopus 로고    scopus 로고
    • Alzheimer's disease: Aβ, tau and synaptic dysfunction
    • LaFerla, F.M. Oddo, S. (2005) Alzheimer's disease: Aβ, tau and synaptic dysfunction. Trends Mol. Med., 11, 170 176.
    • (2005) Trends Mol. Med. , vol.11 , pp. 170-176
    • Laferla, F.M.1    Oddo, S.2
  • 24
    • 33645092125 scopus 로고    scopus 로고
    • Progressive neuronal loss and behavioral impairments of transgenic C57BL/6 inbred mice expressing the carboxy terminus of amyloid precursor protein
    • Lee, K.W., Im, J.Y., Song, J.S., Lee, S.H., Lee, H.J., Ha, H.Y., Koh, J.Y., Gwag, B.J., Yang, S.D., Paik, S.G. Han, P.L. (2006) Progressive neuronal loss and behavioral impairments of transgenic C57BL/6 inbred mice expressing the carboxy terminus of amyloid precursor protein. Neurobiol. Dis., 22, 10 24.
    • (2006) Neurobiol. Dis. , vol.22 , pp. 10-24
    • Lee, K.W.1    Im, J.Y.2    Song, J.S.3    Lee, S.H.4    Lee, H.J.5    Ha, H.Y.6    Koh, J.Y.7    Gwag, B.J.8    Yang, S.D.9    Paik, S.G.10    Han, P.L.11
  • 27
    • 33646126924 scopus 로고    scopus 로고
    • A decade of modeling Alzheimer's disease in transgenic mice
    • McGowan, E., Eriksen, J. Hutton, M. (2006) A decade of modeling Alzheimer's disease in transgenic mice. Trends Genet., 22, 281 289.
    • (2006) Trends Genet. , vol.22 , pp. 281-289
    • McGowan, E.1    Eriksen, J.2    Hutton, M.3
  • 28
    • 0029148814 scopus 로고
    • Implicit memory in Alzheimer's disease: A meta-analysis
    • Meiran, N. Jelicic, M. (1995) Implicit memory in Alzheimer's disease: a meta-analysis. Neuropsychology, 9, 291 303.
    • (1995) Neuropsychology , vol.9 , pp. 291-303
    • Meiran, N.1    Jelicic, M.2
  • 31
    • 33749521100 scopus 로고    scopus 로고
    • Intraneuronal β-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: Potential factors in amyloid plaque formation
    • Oakley, H., Cole, S.L., Logan, S., Maus, E., Shao, P., Craft, J., Guillozet-Bongaarts, A., Ohno, M., Disterhoft, J., Van Eldik, L., Berry, R. Vassar, R. (2006) Intraneuronal β-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: potential factors in amyloid plaque formation. J. Neurosci., 26, 10129 10140.
    • (2006) J. Neurosci. , vol.26 , pp. 10129-10140
    • Oakley, H.1    Cole, S.L.2    Logan, S.3    Maus, E.4    Shao, P.5    Craft, J.6    Guillozet-Bongaarts, A.7    Ohno, M.8    Disterhoft, J.9    Van Eldik, L.10    Berry, R.11    Vassar, R.12
  • 32
    • 33751206536 scopus 로고    scopus 로고
    • Genetic and pharmacological basis for therapeutic inhibition of β- And γ-secretases in mouse models of Alzheimer's memory deficits
    • Ohno, M. (2006) Genetic and pharmacological basis for therapeutic inhibition of β- and γ-secretases in mouse models of Alzheimer's memory deficits. Rev. Neurosci., 17, 429 454.
    • (2006) Rev. Neurosci. , vol.17 , pp. 429-454
    • Ohno, M.1
  • 33
    • 72949097201 scopus 로고    scopus 로고
    • β-Secretase as a prime therapeutic target for Alzheimer's disease: A perspective from mouse model studies
    • In. Araki, W. Ed. Research Signpost. Kerala. pp.
    • Ohno, M. 2008. β-Secretase as a prime therapeutic target for Alzheimer's disease: a perspective from mouse model studies. In Araki, W. (Ed Recent Advances in the Biology of Secretases, Key Proteases in Alzheimer's Disease. Research Signpost, Kerala, pp. 1 25.
    • (2008) Recent Advances in the Biology of Secretases, Key Proteases in Alzheimer's Disease. , pp. 1-25
    • Ohno, M.1
  • 34
    • 72949091844 scopus 로고    scopus 로고
    • Impacts of partial reduction of BACE1 on synaptic and memory dysfunction in Alzheimer's transgenic mice
    • Ohno, M. Kimura, R. (2008) Impacts of partial reduction of BACE1 on synaptic and memory dysfunction in Alzheimer's transgenic mice. Alzheimers Dement., 4 (Suppl 2 T233 T234.
    • (2008) Alzheimers Dement. , vol.4 , Issue.SUPPL 2
    • Ohno, M.1    Kimura, R.2
  • 35
    • 0035204137 scopus 로고    scopus 로고
    • Inducible, pharmacogenetic approaches to the study of learning and memory
    • Ohno, M., Frankland, P.W., Chen, A.P., Costa, R.M. Silva, A.J. (2001) Inducible, pharmacogenetic approaches to the study of learning and memory. Nat. Neurosci., 4, 1238 1243.
    • (2001) Nat. Neurosci. , vol.4 , pp. 1238-1243
    • Ohno, M.1    Frankland, P.W.2    Chen, A.P.3    Costa, R.M.4    Silva, A.J.5
  • 36
    • 0346055155 scopus 로고    scopus 로고
    • BACE1 deficiency rescues memory deficits and cholinergic dysfunction in a mouse model of Alzheimer's disease
    • Ohno, M., Sametsky, E.A., Younkin, L.H., Oakley, H., Younkin, S.G., Citron, M., Vassar, R. Disterhoft, J.F. (2004) BACE1 deficiency rescues memory deficits and cholinergic dysfunction in a mouse model of Alzheimer's disease. Neuron, 41, 27 33.
    • (2004) Neuron , vol.41 , pp. 27-33
    • Ohno, M.1    Sametsky, E.A.2    Younkin, L.H.3    Oakley, H.4    Younkin, S.G.5    Citron, M.6    Vassar, R.7    Disterhoft, J.F.8
  • 39
    • 41049097823 scopus 로고    scopus 로고
    • Acquisition of conditioned taste aversion is impaired in the amyloid precursor protein/presenilin 1 mouse model of Alzheimer's disease
    • Pistell, P.J., Zhu, M. Ingram, D.K. (2008) Acquisition of conditioned taste aversion is impaired in the amyloid precursor protein/presenilin 1 mouse model of Alzheimer's disease. Neuroscience, 152, 594 600.
    • (2008) Neuroscience , vol.152 , pp. 594-600
    • Pistell, P.J.1    Zhu, M.2    Ingram, D.K.3
  • 41
    • 0031724004 scopus 로고    scopus 로고
    • Behavioral and neuropathologic changes induced by central injection of carboxyl-terminal fragment of β-amyloid precursor protein in mice
    • Song, D.K., Won, M.H., Jung, J.S., Lee, J.C., Kang, T.C., Suh, H.W., Huh, S.O., Paek, S.H., Kim, Y.H., Kim, S.H. Suh, Y.H. (1998) Behavioral and neuropathologic changes induced by central injection of carboxyl-terminal fragment of β-amyloid precursor protein in mice. J. Neurochem., 71, 875 878.
    • (1998) J. Neurochem. , vol.71 , pp. 875-878
    • Song, D.K.1    Won, M.H.2    Jung, J.S.3    Lee, J.C.4    Kang, T.C.5    Suh, H.W.6    Huh, S.O.7    Paek, S.H.8    Kim, Y.H.9    Kim, S.H.10    Suh, Y.H.11
  • 42
    • 0026847039 scopus 로고
    • Memory and the hippocampus: A synthesis from findings with rats, monkeys, and humans
    • Squire, L.R. (1992) Memory and the hippocampus: a synthesis from findings with rats, monkeys, and humans. Psychol. Rev., 99, 195 231.
    • (1992) Psychol. Rev. , vol.99 , pp. 195-231
    • Squire, L.R.1
  • 44
    • 38749095507 scopus 로고    scopus 로고
    • The expression of microRNA miR-107 decreases early in Alzheimer's disease and may accelerate disease progression through regulation of β-site amyloid precursor protein-cleaving enzyme 1
    • Wang, W.X., Rajeev, B.W., Stromberg, A.J., Ren, N., Tang, G., Huang, Q., Rigoutsos, I. Nelson, P.T. (2008) The expression of microRNA miR-107 decreases early in Alzheimer's disease and may accelerate disease progression through regulation of β-site amyloid precursor protein-cleaving enzyme 1. J. Neurosci., 28, 1213 1223.
    • (2008) J. Neurosci. , vol.28 , pp. 1213-1223
    • Wang, W.X.1    Rajeev, B.W.2    Stromberg, A.J.3    Ren, N.4    Tang, G.5    Huang, Q.6    Rigoutsos, I.7    Nelson, P.T.8
  • 45
    • 0035829374 scopus 로고    scopus 로고
    • Conditioned taste aversion as a learning and memory paradigm
    • Welzl, H., D'Adamo, P. Lipp, H.P. (2001) Conditioned taste aversion as a learning and memory paradigm. Behav. Brain Res., 125, 205 213.
    • (2001) Behav. Brain Res. , vol.125 , pp. 205-213
    • Welzl, H.1    D'Adamo, P.2    Lipp, H.P.3
  • 46
    • 0025940930 scopus 로고
    • Brain mechanisms of taste aversion learning in the rat
    • Yamamoto, T. Fujimoto, Y. (1991) Brain mechanisms of taste aversion learning in the rat. Brain Res. Bull., 27, 403 406.
    • (1991) Brain Res. Bull. , vol.27 , pp. 403-406
    • Yamamoto, T.1    Fujimoto, Y.2
  • 49
    • 34147120073 scopus 로고    scopus 로고
    • β-Site amyloid precursor protein cleaving enzyme 1 levels become elevated in neurons around amyloid plaques: Implications for Alzheimer's disease pathogenesis
    • Zhao, J., Fu, Y., Yasvoina, M., Shao, P., Hitt, B., O'Connor, T., Logan, S., Maus, E., Citron, M., Berry, R., Binder, L. Vassar, R. (2007) β-Site amyloid precursor protein cleaving enzyme 1 levels become elevated in neurons around amyloid plaques: implications for Alzheimer's disease pathogenesis. J. Neurosci., 27, 3639 3649.
    • (2007) J. Neurosci. , vol.27 , pp. 3639-3649
    • Zhao, J.1    Fu, Y.2    Yasvoina, M.3    Shao, P.4    Hitt, B.5    O'Connor, T.6    Logan, S.7    Maus, E.8    Citron, M.9    Berry, R.10    Binder, L.11    Vassar, R.12


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.