DNA-PKcs deficiency in human: Long predicted, finally found

Current Opinion in Allergy and Clinical Immunology

Volumn 9, Issue 6, 2009, Pages 503-509

  Van Der Burg, Mirjam ^a   Van Dongen, Jacques J M ^a   Van Gent, Dik C ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

DNA double strand break repair; DNA dependent protein kinase catalytic subunit; Nonhomologous end joining; PRKDC; Severe combined immunodeficiency; V(D)Jrecombination

Indexed keywords

DNA; DOUBLE STRANDED DNA; PROTEIN KINASE;

AUTOPHOSPHORYLATION; DNA DAMAGE; DNA DEPEDENT PROTEIN KINASE CATALYTIC SUBUNIT DEFICIENCY; DOUBLE STRANDED DNA BREAK; GENE ACTIVITY; GENE MUTATION; GENE THERAPY; GENETIC RECOMBINATION; HUMAN; IN VITRO STUDY; IN VIVO STUDY; MISSENSE MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVIEW; SEVERE COMBINED IMMUNODEFICIENCY; SPONTANEOUS MUTATION;

ANIMALS; B-LYMPHOCYTES; DNA REPAIR; DNA-ACTIVATED PROTEIN KINASE; GENE REARRANGEMENT, B-LYMPHOCYTE; GENE REARRANGEMENT, T-LYMPHOCYTE; HUMANS; MUTATION; NUCLEAR PROTEINS; RADIATION TOLERANCE; SEVERE COMBINED IMMUNODEFICIENCY; T-LYMPHOCYTES;

EID: 70350786484     PISSN: 15284050     EISSN: 14736322     Source Type: Journal    
DOI: 10.1097/ACI.0b013e3283327e41     Document Type: Review

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