Defective Artemis nuclease in characterized by coding joints with microhomology in long palindromic-nucleotide stretches

European Journal of Immunology

Volumn 37, Issue 12, 2007, Pages 3522-3528

  van der Burg, Mirjam ^a   Verkaik, Nicole S ^a   den Dekker, Alexander T ^a   Barendregt, Barbara H ^a   Pico Knijnenburg, Ingrid ^a   Tezcan, Ilhan ^b   vanDongen, Jacques J M ^a   van Gent, Dik C ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b HACETTEPE UNIVERSITY   (Turkey)

Author keywords

Gene rearrangement; Human; Immunodeficiency diseases; Molecular biology

Indexed keywords

ARTEMIS; NUCLEASE; PALINDROMIC DNA; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; B LYMPHOCYTE; BONE MARROW CELL; CARBOXY TERMINAL SEQUENCE; COMBINED IMMUNODEFICIENCY; CONTROLLED STUDY; DNA SEQUENCE; GENE DELETION; GENE MAPPING; GENE OVEREXPRESSION; GENE REARRANGEMENT; GENETIC RECOMBINATION; HUMAN; HUMAN CELL; MUTATIONAL ANALYSIS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROLYMPHOCYTE; PROTEIN EXPRESSION; RISK FACTOR; SEQUENCE HOMOLOGY;

BINDING SITES; CELLS, CULTURED; GENE REARRANGEMENT, B-LYMPHOCYTE, HEAVY CHAIN; GENETIC COMPLEMENTATION TEST; HUMANS; IMMUNOGLOBULIN JOINING REGION; INFANT; NUCLEAR PROTEINS; NUCLEIC ACID CONFORMATION; PRECURSOR CELLS, B-LYMPHOID; PROTEIN STRUCTURE, TERTIARY; RADIATION TOLERANCE; RECOMBINANT FUSION PROTEINS; REPETITIVE SEQUENCES, NUCLEIC ACID; SEQUENCE HOMOLOGY, NUCLEIC ACID; SEVERE COMBINED IMMUNODEFICIENCY; STRUCTURE-ACTIVITY RELATIONSHIP; VDJ RECOMBINASES;

EID: 37549055036     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.200737624     Document Type: Article

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