Identification of a nonsense mutation in the carboxyl-terminal region of DNA-dependent protein kinase catalytic subunit in the scid mouse

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 19, 1996, Pages 10285-10290

  Blunt, Tracy ^a   Gell, David ^b   Fox, Margaret ^c   Taccioli, Guillermo E ^d   Lehmann, Alan R ^a   Jackson, Stephen P ^b   Jeggo, Penny A ^a  

^a UNIVERSITY OF SUSSEX   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c MEDICAL RESEARCH COUNCIL   (United Kingdom)

^d BOSTON UNIVERSITY   (United States)

Author keywords

irradiation; double strand break repair; immune development; phosphatidylinositol 3 kinase; V(D)J recombination

Indexed keywords

DNA DIRECTED PROTEIN KINASE; DOUBLE STRANDED DNA; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DNA REPAIR; DNA SEQUENCE; DNA STRAND BREAKAGE; DNA SYNTHESIS; ENZYME ACTIVE SITE; GENETIC RECOMBINATION; HAMSTER; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; NONSENSE MUTATION; NORTHERN BLOTTING; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SCID MOUSE;

3T3 CELLS; ALTERNATIVE SPLICING; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CELL LINE; CHO CELLS; CRICETINAE; DNA PRIMERS; DNA-ACTIVATED PROTEIN KINASE; DNA-BINDING PROTEINS; EVOLUTION, MOLECULAR; EXONS; GENE LIBRARY; HUMANS; MICE; MICE, SCID; MOLECULAR SEQUENCE DATA; MUTATION; NUCLEAR PROTEINS; POLYMERASE CHAIN REACTION; PROTEIN-SERINE-THREONINE KINASES; RODENTIA; SEQUENCE HOMOLOGY, AMINO ACID; TRANSCRIPTION, GENETIC;

ANIMALIA; CRICETINAE; RODENTIA;

EID: 0029788520     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.19.10285     Document Type: Article

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