-
1
-
-
0142025259
-
Interactive competition between homologous recombination and non-homologous end joining
-
Allen, C., J. Halbrook, and J. A. Nickoloff. 2003. Interactive competition between homologous recombination and non-homologous end joining. Mol. Cancer Res. 1:913-920.
-
(2003)
Mol. Cancer Res.
, vol.1
, pp. 913-920
-
-
Allen, C.1
Halbrook, J.2
Nickoloff, J.A.3
-
2
-
-
4043073590
-
Autophosphorylation-dependent remodeling of the DNA-dependent protein kinase catalytic subunit (DNA-PKcs) regulates ligation of DNA ends
-
Block, W., Y. Yu, D. Merkle, J. Gifford, Q. Ding, K. Meek, and S. P. Lies-Miller. 2004. Autophosphorylation-dependent remodeling of the DNA-dependent protein kinase catalytic subunit (DNA-PKcs) regulates ligation of DNA ends. Nucleic Acids Res. 32:4351-4357.
-
(2004)
Nucleic Acids Res.
, vol.32
, pp. 4351-4357
-
-
Block, W.1
Yu, Y.2
Merkle, D.3
Gifford, J.4
Ding, Q.5
Meek, K.6
Lies-Miller, S.P.7
-
3
-
-
0037423743
-
Coordinated assembly of Ku and p460 subunits of the DNA-dependent protein kinase on DNA ends is necessary for XRCC4-ligase IV recruitment
-
Calsou, P., C. Delteil, P. Frit, J. Drouet, and B. Salles. 2003. Coordinated assembly of Ku and p460 subunits of the DNA-dependent protein kinase on DNA ends is necessary for XRCC4-ligase IV recruitment. J. Mol. Biol. 326:93-103.
-
(2003)
J. Mol. Biol.
, vol.326
, pp. 93-103
-
-
Calsou, P.1
Delteil, C.2
Frit, P.3
Drouet, J.4
Salles, B.5
-
4
-
-
0037106180
-
Autophosphorylation of the DNA-dependent protein kinase catalytic subunit is required for rejoining of DNA double-strand breaks
-
Chan., D. W., B. P. Chen, S. Prithivirajsingh, A. Kurimasa, M. D. Story, J. Qin, and D. J. Chen. 2002. Autophosphorylation of the DNA-dependent protein kinase catalytic subunit is required for rejoining of DNA double-strand breaks. Genes Dev. 16:2333-2338.
-
(2002)
Genes Dev.
, vol.16
, pp. 2333-2338
-
-
Chan, D.W.1
Chen, B.P.2
Prithivirajsingh, S.3
Kurimasa, A.4
Story, M.D.5
Qin, J.6
Chen, D.J.7
-
5
-
-
0030009738
-
The DNA-dependent protein kinase is inactivated by autophosphorylation of the catalytic subunit
-
Chan, D. W., and S. P. Lees-Miller. 1996. The DNA-dependent protein kinase is inactivated by autophosphorylation of the catalytic subunit. J. Biol. Chem. 271:8936-8941.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 8936-8941
-
-
Chan, D.W.1
Lees-Miller, S.P.2
-
6
-
-
0032972734
-
DNA-dependent protein kinase phosphorylation sites in Ku 70/80 heterodimer
-
Chan, D. W., R. Ye, C. J. Veillette, and S. P. Lies-Miller. 1999. DNA-dependent protein kinase phosphorylation sites in Ku 70/80 heterodimer. Biochemistry 38:1819-1828.
-
(1999)
Biochemistry
, vol.38
, pp. 1819-1828
-
-
Chan, D.W.1
Ye, R.2
Veillette, C.J.3
Lies-Miller, S.P.4
-
7
-
-
17644384427
-
Cell cycle dependence of DNA-dependent protein kinase phosphorylation in response to DNA double strand breaks
-
Chen, B. P., D. W. Chan, J. Kobayashi, S. Burma, A. Asaithamby, K. Morotomi-Yano, E. Botvinick, J. Qin, and D. J. Chen. 2005. Cell cycle dependence of DNA-dependent protein kinase phosphorylation in response to DNA double strand breaks. J. Biol. Chem. 280:14709-14715.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 14709-14715
-
-
Chen, B.P.1
Chan, D.W.2
Kobayashi, J.3
Burma, S.4
Asaithamby, A.5
Morotomi-Yano, K.6
Botvinick, E.7
Qin, J.8
Chen, D.J.9
-
8
-
-
13444263265
-
Inhibition of homologous recombination by variants of DNA-PKcs
-
Convery, E., E. K. Shin, Q. Ding, W. Wang, P. Douglas, J. A. Nickoloff, S. P. Lees-Miller, and K. Meek. 2005. Inhibition of homologous recombination by variants of DNA-PKcs. Proc. Natl. Acad. Sci. USA 102:1345-1350.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 1345-1350
-
-
Convery, E.1
Shin, E.K.2
Ding, Q.3
Wang, W.4
Douglas, P.5
Nickoloff, J.A.6
Lees-Miller, S.P.7
Meek, K.8
-
9
-
-
0043133778
-
Autophosphorylation of the catalytic subunit of the DNA-dependent protein kinase is required for efficient end processing during DNA double-strand break repair
-
Ding, Q., Y. V. Reddy, W. Wang, T. Woods, P. Douglas, D. A. Ramsden, S. P. Lees-Miller, and K. Meek. 2003. Autophosphorylation of the catalytic subunit of the DNA-dependent protein kinase is required for efficient end processing during DNA double-strand break repair. Mol. Cell. Biol. 23:5836-5848.
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 5836-5848
-
-
Ding, Q.1
Reddy, Y.V.2
Wang, W.3
Woods, T.4
Douglas, P.5
Ramsden, D.A.6
Lees-Miller, S.P.7
Meek, K.8
-
10
-
-
3142685133
-
Binding of the DNA-dependent protein kinase catalytic subunit to Holliday junctions
-
Dip, R., and H. Naegeli. 2004. Binding of the DNA-dependent protein kinase catalytic subunit to Holliday junctions. Biochem. J. 381:165-174.
-
(2004)
Biochem. J.
, vol.381
, pp. 165-174
-
-
Dip, R.1
Naegeli, H.2
-
11
-
-
0035374588
-
Protein phosphatases regulate DNA-dependent protein kinase activity
-
Douglas, P., G. B. Moorhead, R. Ye, and S. P. Lees-Miller, S. P. 2001. Protein phosphatases regulate DNA-dependent protein kinase activity. J. Biol. Chem. 276:18992-18998.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 18992-18998
-
-
Douglas, P.1
Moorhead, G.B.2
Ye, R.3
Lees-Miller, S.P.4
-
12
-
-
2242484657
-
Identification of in vitro and in vivo phosphorylation sites in the catalytic subunit of the DNA-dependent protein kinase
-
Douglas, P., G. P. Sapkota, N. Morrice, Y. Yu, A. A. Goodarzi, D. Merkle, K. Meek, D. R. Alessi, and S. P. Lees-Miller. 2002. Identification of in vitro and in vivo phosphorylation sites in the catalytic subunit of the DNA-dependent protein kinase. Biochem. J. 368:243-251.
-
(2002)
Biochem. J.
, vol.368
, pp. 243-251
-
-
Douglas, P.1
Sapkota, G.P.2
Morrice, N.3
Yu, Y.4
Goodarzi, A.A.5
Merkle, D.6
Meek, K.7
Alessi, D.R.8
Lees-Miller, S.P.9
-
13
-
-
14844292557
-
DNA-dependent protein kinase and XRCC4-DNA ligase IV mobilization in the cell in response to DNA double strand breaks
-
Drouet, J., C. Delteil, J. Lefrancois, P. Concannon, B. Salles, and P. Calsou. 2005. DNA-dependent protein kinase and XRCC4-DNA ligase IV mobilization in the cell in response to DNA double strand breaks. J. Biol. Chem. 280:7060-7069.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 7060-7069
-
-
Drouet, J.1
Delteil, C.2
Lefrancois, J.3
Concannon, P.4
Salles, B.5
Calsou, P.6
-
14
-
-
15844373362
-
CDK-dependent phosphorylation of BRCA2 as a regulatory mechanism for recombinational repair
-
Esashi, F., N. Christ, J. Gannon, Y. Liu, T. Hunt, M. Jasin, and S. C. West. 2005. CDK-dependent phosphorylation of BRCA2 as a regulatory mechanism for recombinational repair. Nature 434:598-604.
-
(2005)
Nature
, vol.434
, pp. 598-604
-
-
Esashi, F.1
Christ, N.2
Gannon, J.3
Liu, Y.4
Hunt, T.5
Jasin, M.6
West, S.C.7
-
15
-
-
3242880238
-
H2AX: The histone guardian of the genome
-
Fernandez-Capetillo, O., A. Lee, M. Nussenzweig, and A. Nussenzweig. 2004. H2AX: the histone guardian of the genome. DNA Repair 3:959-967.
-
(2004)
DNA Repair
, vol.3
, pp. 959-967
-
-
Fernandez-Capetillo, O.1
Lee, A.2
Nussenzweig, M.3
Nussenzweig, A.4
-
16
-
-
0026349985
-
Selective cleavage of human RecA-assisted restriction endonuclease (RARE) cleavage
-
Ferrin, L. J., and R D. Camerini-Otero. 1991. Selective cleavage of human RecA-assisted restriction endonuclease (RARE) cleavage. Science 54:1494-1497.
-
(1991)
Science
, vol.54
, pp. 1494-1497
-
-
Ferrin, L.J.1
Camerini-Otero, R.D.2
-
17
-
-
2642543876
-
Biochemical characterization of the ataxia-telangiectasia mutated (ATM) protein from human cells
-
Goodarzi, A. A., and S. P. Lees-Miller. 2004. Biochemical characterization of the ataxia-telangiectasia mutated (ATM) protein from human cells. DNA Repair 3:753-767.
-
(2004)
DNA Repair
, vol.3
, pp. 753-767
-
-
Goodarzi, A.A.1
Lees-Miller, S.P.2
-
18
-
-
0037187199
-
Defining interactions between DNA-PK and ligase IV/XRCC4
-
Hsu, H. L., S. M. Yannone, and D. J. Chen. 2002. Defining interactions between DNA-PK and ligase IV/XRCC4. DNA Repair 1:225-235.
-
(2002)
DNA Repair
, vol.1
, pp. 225-235
-
-
Hsu, H.L.1
Yannone, S.M.2
Chen, D.J.3
-
19
-
-
0032404178
-
Double-strand break repair in Ku86- and XRCC4-deficient cells
-
Kabotyanski, E. B., L. Gomelsky, J. O. Hanc, T. D. Stamato, and D. B. Roth. 1998. Double-strand break repair in Ku86- and XRCC4-deficient cells. Nucleic Acids Res. 26:5333-5342.
-
(1998)
Nucleic Acids Res.
, vol.26
, pp. 5333-5342
-
-
Kabotyanski, E.B.1
Gomelsky, L.2
Hanc, J.O.3
Stamato, T.D.4
Roth, D.B.5
-
20
-
-
0034662228
-
Both V(D)J recombination and radioresistance require DNA-PK kinase activity, though minimal levels suffice for V(D)J recombination
-
Kienker, L. J., E. K. Shin, and K. Meek. 2000. Both V(D)J recombination and radioresistance require DNA-PK kinase activity, though minimal levels suffice for V(D)J recombination. Nucleic Acids Res. 28:2752-2761.
-
(2000)
Nucleic Acids Res.
, vol.28
, pp. 2752-2761
-
-
Kienker, L.J.1
Shin, E.K.2
Meek, K.3
-
21
-
-
0032938747
-
Requirement for the kinase activity of human DNA-dependent protein kinase catalytic subunit in DNA strand break rejoining
-
Kurimasa, A., S. Kumano, N. V. Boubnov, M. D. Story, C. S. Tung, S. R. Peterson, and D. J. Chen. 1999. Requirement for the kinase activity of human DNA-dependent protein kinase catalytic subunit in DNA strand break rejoining. Mol. Cell. Biol. 19:3877-3884.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 3877-3884
-
-
Kurimasa, A.1
Kumano, S.2
Boubnov, N.V.3
Story, M.D.4
Tung, C.S.5
Peterson, S.R.6
Chen, D.J.7
-
22
-
-
0031939411
-
The XRCC4 gene product is a target for and interacts with the DNA-dependent protein kinase
-
Leber, R., T. W. Wise, R. Mizuta, and K. Meek. 1998. The XRCC4 gene product is a target for and interacts with the DNA-dependent protein kinase. J. Biol. Chem. 273:1794-1801.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 1794-1801
-
-
Leber, R.1
Wise, T.W.2
Mizuta, R.3
Meek, K.4
-
23
-
-
0942268167
-
Repair of DNA double strand breaks by non-homologous end joining
-
Lees-Miller, S. P., and K. Meek. 2003. Repair of DNA double strand breaks by non-homologous end joining. Biochemie 85:1161-1173.
-
(2003)
Biochemie
, vol.85
, pp. 1161-1173
-
-
Lees-Miller, S.P.1
Meek, K.2
-
24
-
-
0037155703
-
Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination
-
Ma, Y., U. Pannicke, K. Schwarz, and M. R. Lieber. 2002. Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination. Cell 108:781-794.
-
(2002)
Cell
, vol.108
, pp. 781-794
-
-
Ma, Y.1
Pannicke, U.2
Schwarz, K.3
Lieber, M.R.4
-
25
-
-
3242875642
-
DNA-PK: Activity director at the end
-
Meek, K., S. Gupta, D. A. Ramsden, and S. P. Lees-Miller. 2004. DNA-PK: activity director at the end. Immunol. Rev. 200:132-141.
-
(2004)
Immunol. Rev.
, vol.200
, pp. 132-141
-
-
Meek, K.1
Gupta, S.2
Ramsden, D.A.3
Lees-Miller, S.P.4
-
26
-
-
0037159220
-
The DNA-dependent protein kinase interacts with DNA to form a protein-DNA complex that is disrupted by phosphorylation
-
Merkle, D., P. Douglas, G. B. Moorhead, Z. Leonenko, Y. Yu, D. Cramb, D. P. Bazett-Jones, and S. P. Lies-Miller. 2002. The DNA-dependent protein kinase interacts with DNA to form a protein-DNA complex that is disrupted by phosphorylation. Biochemistry 41:12706-12714.
-
(2002)
Biochemistry
, vol.41
, pp. 12706-12714
-
-
Merkle, D.1
Douglas, P.2
Moorhead, G.B.3
Leonenko, Z.4
Yu, Y.5
Cramb, D.6
Bazett-Jones, D.P.7
Lies-Miller, S.P.8
-
27
-
-
0035893363
-
Ku DNA end-binding protein modulates homologous repair of double-strand breaks in mammalian cells
-
Pierce, A. J., P. Hu, M. Han, N. Ellis, and M. Jasin. 2001. Ku DNA end-binding protein modulates homologous repair of double-strand breaks in mammalian cells. Genes Dev. 15:3237-3242.
-
(2001)
Genes Dev.
, vol.15
, pp. 3237-3242
-
-
Pierce, A.J.1
Hu, P.2
Han, M.3
Ellis, N.4
Jasin, M.5
-
28
-
-
4544295689
-
Nonhomologous end-joining requires that the DNA-PK complex undergo an autophosphorylation-dependent rearrangement at DNA ends
-
Reddy, V., Q. Ding, S. P. Lees-Miller, K. Meek, and D. A. Ramsden. 2004. Nonhomologous end-joining requires that the DNA-PK complex undergo an autophosphorylation-dependent rearrangement at DNA ends. J. Biol. Chem. 279:39408-39413.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 39408-39413
-
-
Reddy, V.1
Ding, Q.2
Lees-Miller, S.P.3
Meek, K.4
Ramsden, D.A.5
-
29
-
-
9744220428
-
A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to γ-H2AX foci
-
Riballo, E., M. Kuhne, N. Rief, A. Doherty, G. C. Smith, M. J. Recio, C. Reis, K. Dahm, A. Fricke, A. Krempler, A. R. Parker, S. P. Jackson, A. Gennery, P. A. Jeggo, and M. Lobrich. 2004. A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to γ-H2AX foci. Mol. Cell 16:715-724.
-
(2004)
Mol. Cell
, vol.16
, pp. 715-724
-
-
Riballo, E.1
Kuhne, M.2
Rief, N.3
Doherty, A.4
Smith, G.C.5
Recio, M.J.6
Reis, C.7
Dahm, K.8
Fricke, A.9
Krempler, A.10
Parker, A.R.11
Jackson, S.P.12
Gennery, A.13
Jeggo, P.A.14
Lobrich, M.15
-
30
-
-
0042632901
-
Pathways of DNA double-strand break repair during the mammalian cell cycle
-
Rolhkamm, K., I. Kruger, L. H. Thompson, and M. Lobrich. 2003. Pathways of DNA double-strand break repair during the mammalian cell cycle. Mol. Cell. Biol. 23:5706-5715.
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 5706-5715
-
-
Rolhkamm, K.1
Kruger, I.2
Thompson, L.H.3
Lobrich, M.4
-
32
-
-
0034132349
-
Analyses of TCRB rearrangements substantiate a profound deficit in recombination signal sequence joining in SCID foals: Implications for the role of DNA-dependent protein kinase in V(D)J recombination
-
Shin, E. K., T. Rijkers, A. Pastink, and K. Meek. 2000. Analyses of TCRB rearrangements substantiate a profound deficit in recombination signal sequence joining in SCID foals: implications for the role of DNA-dependent protein kinase in V(D)J recombination. J. Immunol. 164:1416-1424.
-
(2000)
J. Immunol.
, vol.164
, pp. 1416-1424
-
-
Shin, E.K.1
Rijkers, T.2
Pastink, A.3
Meek, K.4
-
33
-
-
0037444375
-
Threonines 2638/2647 in DNA-PK are essential for cellular resistance to ionizing radiation
-
Soubeyrand, S., L. Pope, B. Pakuts, and R. J. Hache. 2003. Threonines 2638/2647 in DNA-PK are essential for cellular resistance to ionizing radiation. Cancer Res. 63:1198-1201.
-
(2003)
Cancer Res.
, vol.63
, pp. 1198-1201
-
-
Soubeyrand, S.1
Pope, L.2
Pakuts, B.3
Hache, R.J.4
-
34
-
-
0035859812
-
Activation and autoregulation of DNA-PK from structured single-stranded DNA and coding end hairpins
-
Soubeyrand, S., H. Torrance, W. Giffin, W. Gong, C. Schild-Poulter, and R. J. Hache. 2001. Activation and autoregulation of DNA-PK from structured single-stranded DNA and coding end hairpins. Proc. Natl. Acad. Sci. USA 98:9605-9610.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 9605-9610
-
-
Soubeyrand, S.1
Torrance, H.2
Giffin, W.3
Gong, W.4
Schild-Poulter, C.5
Hache, R.J.6
-
35
-
-
0842320995
-
DNA-PKcs function regulated specifically by protein phosphatase 5
-
Wechsler, T., B. P. Chen, R. Harper, K. Morotomi-Yano, B. C. Huang, K. Meek, J. E. Cleaver, D. J. Chen, and M. Wabl. 2004. DNA-PKcs function regulated specifically by protein phosphatase 5. Proc. Natl. Acad. Sci. USA 101:1247-1252.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 1247-1252
-
-
Wechsler, T.1
Chen, B.P.2
Harper, R.3
Morotomi-Yano, K.4
Huang, B.C.5
Meek, K.6
Cleaver, J.E.7
Chen, D.J.8
Wabl, M.9
-
36
-
-
0348149145
-
The role of DNA dependent protein kinase in synapsis of DNA ends
-
Weterings, E., N. S. Verkaik, H. T. Bruggenwirth, J. H. J. Hoeijmakers, and D. C. van Gent. 2003. The role of DNA dependent protein kinase in synapsis of DNA ends. Nucleic Acids Res. 31:7238-7246.
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 7238-7246
-
-
Weterings, E.1
Verkaik, N.S.2
Bruggenwirth, H.T.3
Hoeijmakers, J.H.J.4
Van Gent, D.C.5
-
37
-
-
0242268028
-
DNA-PK phosphorylation sites in XRCC4 are not required for survival after radiation or for V(D)J recombination
-
Yu, Y., W. Wang, Q. Ding, R. Ye, D. Chen, D. Merkle, D. Schriemer, K. Meek, and S. P. Lees-Miller. 2003. DNA-PK phosphorylation sites in XRCC4 are not required for survival after radiation or for V(D)J recombination. DNA Repair 2:1239-1252.
-
(2003)
DNA Repair
, vol.2
, pp. 1239-1252
-
-
Yu, Y.1
Wang, W.2
Ding, Q.3
Ye, R.4
Chen, D.5
Merkle, D.6
Schriemer, D.7
Meek, K.8
Lees-Miller, S.P.9
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