-
1
-
-
0034471041
-
Report of a WHO consultation
-
Obesity: preventing and managing the global epidemic.
-
Obesity: preventing and managing the global epidemic. Report of a WHO consultation. World Health Organ Tech Rep Ser 2000 894 : i xii, 1 253.
-
(2000)
World Health Organ Tech Rep ser
, vol.894
, pp. 1-253
-
-
-
2
-
-
33645523067
-
Prevalence of overweight and obesity in the United States, 1999-2004
-
Ogden CL, Carroll MD, Curtin LR, McDowell MA, Tabak CJ, Flegal KM. Prevalence of overweight and obesity in the United States, 1999-2004. JAMA 2006 295 : 1549 1555.
-
(2006)
JAMA
, vol.295
, pp. 1549-1555
-
-
Ogden, C.L.1
Carroll, M.D.2
Curtin, L.R.3
McDowell, M.A.4
Tabak, C.J.5
Flegal, K.M.6
-
3
-
-
0030914127
-
Obesity - The inevitable penalty of civilisation?
-
Prentice AM. Obesity - the inevitable penalty of civilisation? Br Med Bull 1997 53 : 229 237.
-
(1997)
Br Med Bull
, vol.53
, pp. 229-237
-
-
Prentice, A.M.1
-
4
-
-
0032577404
-
Environmental contributions to the obesity epidemic
-
Hill JO, Peters JC. Environmental contributions to the obesity epidemic. Science 1998 280 : 1371 1374.
-
(1998)
Science
, vol.280
, pp. 1371-1374
-
-
Hill, J.O.1
Peters, J.C.2
-
5
-
-
0036852663
-
Physical activity and its impact on health outcomes. Paper 2: Prevention of unhealthy weight gain and obesity by physical activity: An analysis of the evidence
-
Erlichman J, Kerbey AL, James WP. Physical activity and its impact on health outcomes. Paper 2: prevention of unhealthy weight gain and obesity by physical activity: an analysis of the evidence. Obes Rev 2002 3 : 273 287.
-
(2002)
Obes Rev
, vol.3
, pp. 273-287
-
-
Erlichman, J.1
Kerbey, A.L.2
James, W.P.3
-
6
-
-
33747870163
-
Overweight, obesity, and mortality in a large prospective cohort of persons 50 to 71 years old
-
Adams KF, Schatzkin A, Harris TB, Kipnis V, Mouw T, Ballard-Barbash R, Hollenbeck A, Leitzmann MF. Overweight, obesity, and mortality in a large prospective cohort of persons 50 to 71 years old. N Engl J Med 2006 355 : 763 778.
-
(2006)
N Engl J Med
, vol.355
, pp. 763-778
-
-
Adams, K.F.1
Schatzkin, A.2
Harris, T.B.3
Kipnis, V.4
Mouw, T.5
Ballard-Barbash, R.6
Hollenbeck, A.7
Leitzmann, M.F.8
-
7
-
-
37349066531
-
International day for the evaluation of abdominal obesity (IDEA): A study of waist circumference, cardiovascular disease, and diabetes mellitus in 168 000 primary care patients in 63 countries
-
Balkau B, Deanfield JE, Despres JP, Bassand JP, Fox KA, Smith SC Jr., Barter P, Tan CE, Van Gaal L, Wittchen HU, Massien C, Haffner SM. International day for the evaluation of abdominal obesity (IDEA): a study of waist circumference, cardiovascular disease, and diabetes mellitus in 168 000 primary care patients in 63 countries. Circulation 2007 116 : 1942 1951.
-
(2007)
Circulation
, vol.116
, pp. 1942-1951
-
-
Balkau, B.1
Deanfield, J.E.2
Despres, J.P.3
Bassand, J.P.4
Fox, K.A.5
Smith Jr., S.C.6
Barter, P.7
Tan, C.E.8
Van Gaal, L.9
Wittchen, H.U.10
Massien, C.11
Haffner, S.M.12
-
8
-
-
25444482392
-
Brain regulation of food intake and appetite: Molecules and networks
-
Broberger C. Brain regulation of food intake and appetite: molecules and networks. J Intern Med 2005 258 : 301 327.
-
(2005)
J Intern Med
, vol.258
, pp. 301-327
-
-
Broberger, C.1
-
9
-
-
33748931457
-
Central nervous system control of food intake and body weight
-
Morton GJ, Cummings DE, Baskin DG, Barsh GS, Schwartz MW. Central nervous system control of food intake and body weight. Nature 2006 443 : 289 295.
-
(2006)
Nature
, vol.443
, pp. 289-295
-
-
Morton, G.J.1
Cummings, D.E.2
Baskin, D.G.3
Barsh, G.S.4
Schwartz, M.W.5
-
12
-
-
0242383401
-
Obesity - Is it a genetic disorder?
-
Loos RJ, Bouchard C. Obesity - is it a genetic disorder? J Intern Med 2003 254 : 401 425.
-
(2003)
J Intern Med
, vol.254
, pp. 401-425
-
-
Loos, R.J.1
Bouchard, C.2
-
13
-
-
33846032275
-
Gastrointestinal regulation of food intake
-
Cummings DE, Overduin J. Gastrointestinal regulation of food intake. J Clin Invest 2007 117 : 13 23.
-
(2007)
J Clin Invest
, vol.117
, pp. 13-23
-
-
Cummings, D.E.1
Overduin, J.2
-
14
-
-
0037288941
-
Insulin and leptin revisited: Adiposity signals with overlapping physiological and intracellular signaling capabilities
-
Niswender KD, Schwartz MW. Insulin and leptin revisited: adiposity signals with overlapping physiological and intracellular signaling capabilities. Front Neuroendocrinol 2003 24 : 1 10.
-
(2003)
Front Neuroendocrinol
, vol.24
, pp. 1-10
-
-
Niswender, K.D.1
Schwartz, M.W.2
-
15
-
-
0034703229
-
Role of brain insulin receptor in control of body weight and reproduction
-
Bruning JC, Gautam D, Burks DJ, Gillette J, Schubert M, Orban PC, Klein R, Krone W, Muller-Wieland D, Kahn CR. Role of brain insulin receptor in control of body weight and reproduction. Science 2000 289 : 2122 2125.
-
(2000)
Science
, vol.289
, pp. 2122-2125
-
-
Bruning, J.C.1
Gautam, D.2
Burks, D.J.3
Gillette, J.4
Schubert, M.5
Orban, P.C.6
Klein, R.7
Krone, W.8
Muller-Wieland, D.9
Kahn, C.R.10
-
19
-
-
17844401704
-
Anatomy and regulation of the central melanocortin system
-
Cone RD. Anatomy and regulation of the central melanocortin system. Nat Neurosci 2005 8 : 571 578.
-
(2005)
Nat Neurosci
, vol.8
, pp. 571-578
-
-
Cone, R.D.1
-
20
-
-
8544226258
-
Induction of brain-region-specific forms of obesity by agouti
-
Kas MJ, Tiesjema B, van Dijk G, Garner KM, Barsh GS, ter Brake O, Verhaagen J, Adan RA. Induction of brain-region-specific forms of obesity by agouti. J Neurosci 2004 24 : 10176 10181.
-
(2004)
J Neurosci
, vol.24
, pp. 10176-10181
-
-
Kas, M.J.1
Tiesjema, B.2
Van Dijk, G.3
Garner, K.M.4
Barsh, G.S.5
Ter Brake, O.6
Verhaagen, J.7
Adan, R.A.8
-
21
-
-
2342484365
-
Hypothalamic control of energy balance: Different peptides, different functions
-
Leibowitz SF, Wortley KE. Hypothalamic control of energy balance: different peptides, different functions. Peptides 2004 25 : 473 504.
-
(2004)
Peptides
, vol.25
, pp. 473-504
-
-
Leibowitz, S.F.1
Wortley, K.E.2
-
22
-
-
0032489093
-
Orexins and orexin receptors: A family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior
-
Sakurai T, Amemiya A, Ishii M, Matsuzaki I, Chemelli RM, Tanaka H, Williams SC, Richarson JA, Kozlowski GP, Wilson S, Arch JR, Buckingham RE, Haynes AC, Carr SA, Annan RS, McNulty DE, Liu WS, Terrett JA, Elshourbagy NA, Bergsma DJ, Yanagisawa M. Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. Cell 1998 92 : 573 585.
-
(1998)
Cell
, vol.92
, pp. 573-585
-
-
Sakurai, T.1
Amemiya, A.2
Ishii, M.3
Matsuzaki, I.4
Chemelli, R.M.5
Tanaka, H.6
Williams, S.C.7
Richarson, J.A.8
Kozlowski, G.P.9
Wilson, S.10
Arch, J.R.11
Buckingham, R.E.12
Haynes, A.C.13
Carr, S.A.14
Annan, R.S.15
McNulty, D.E.16
Liu, W.S.17
Terrett, J.A.18
Elshourbagy, N.A.19
Bergsma, D.J.20
Yanagisawa, M.21
more..
-
23
-
-
0038392755
-
Brain-derived neurotrophic factor regulates energy balance downstream of melanocortin-4 receptor
-
Xu B, Goulding EH, Zang K, Cepoi D, Cone RD, Jones KR, Tecott LH, Reichardt LF. Brain-derived neurotrophic factor regulates energy balance downstream of melanocortin-4 receptor. Nat Neurosci 2003 6 : 736 742.
-
(2003)
Nat Neurosci
, vol.6
, pp. 736-742
-
-
Xu, B.1
Goulding, E.H.2
Zang, K.3
Cepoi, D.4
Cone, R.D.5
Jones, K.R.6
Tecott, L.H.7
Reichardt, L.F.8
-
24
-
-
33749017409
-
The Human Obesity Gene Map: The 2005 update
-
Rankinen T, Zuberi A, Chagnon YC, Weisnagel SJ, Argyropoulos G, Walts B, Perusse L, Bouchard C. The Human Obesity Gene Map: the 2005 update. Obesity (Silver Spring) 2006 14 : 529 644.
-
(2006)
Obesity (Silver Spring)
, vol.14
, pp. 529-644
-
-
Rankinen, T.1
Zuberi, A.2
Chagnon, Y.C.3
Weisnagel, S.J.4
Argyropoulos, G.5
Walts, B.6
Perusse, L.7
Bouchard, C.8
-
25
-
-
33645470268
-
Agouti-related protein promoter variant associated with leanness and decreased risk for diabetes in West Africans
-
Bonilla C, Panguluri RK, Taliaferro-Smith L, Argyropoulos G, Chen G, Adeyemo AA, Amoah A, Owusu S, Acheampong J, Agyenim-Boateng K, Eghan BA, Oli J, Okafor G, Abbiyesuku F, Johnson T, Rufus T, Fasanmade O, Chen Y, Collins FS, Dunston GM, Rotimi C, Kittles RA. Agouti-related protein promoter variant associated with leanness and decreased risk for diabetes in West Africans. Int J Obes (Lond) 2006 30 : 715 721.
-
(2006)
Int J Obes (Lond)
, vol.30
, pp. 715-721
-
-
Bonilla, C.1
Panguluri, R.K.2
Taliaferro-Smith, L.3
Argyropoulos, G.4
Chen, G.5
Adeyemo, A.A.6
Amoah, A.7
Owusu, S.8
Acheampong, J.9
Agyenim-Boateng, K.10
Eghan, B.A.11
Oli, J.12
Okafor, G.13
Abbiyesuku, F.14
Johnson, T.15
Rufus, T.16
Fasanmade, O.17
Chen, Y.18
Collins, F.S.19
Dunston, G.M.20
Rotimi, C.21
Kittles, R.A.22
more..
-
26
-
-
33847207165
-
Family trios analysis of common polymorphisms in the obestatin/ghrelin, BDNF and AGRP genes in patients with Anorexia nervosa: Association with subtype, body-mass index, severity and age of onset
-
Dardennes RM, Zizzari P, Tolle V, Foulon C, Kipman A, Romo L, Iancu-Gontard D, Boni C, Sinet PM, Therese Bluet M, Estour B, Mouren MC, Guelfi JD, Rouillon F, Gorwood P, Epelbaum J. Family trios analysis of common polymorphisms in the obestatin/ghrelin, BDNF and AGRP genes in patients with Anorexia nervosa: association with subtype, body-mass index, severity and age of onset. Psychoneuroendocrinology 2007 32 : 106 113.
-
(2007)
Psychoneuroendocrinology
, vol.32
, pp. 106-113
-
-
Dardennes, R.M.1
Zizzari, P.2
Tolle, V.3
Foulon, C.4
Kipman, A.5
Romo, L.6
Iancu-Gontard, D.7
Boni, C.8
Sinet, P.M.9
Therese Bluet, M.10
Estour, B.11
Mouren, M.C.12
Guelfi, J.D.13
Rouillon, F.14
Gorwood, P.15
Epelbaum, J.16
-
27
-
-
33744958340
-
BDNF Val66Met polymorphism is associated with body mass index in healthy adults
-
Gunstad J, Schofield P, Paul RH, Spitznagel MB, Cohen RA, Williams LM, Kohn M, Gordon E. BDNF Val66Met polymorphism is associated with body mass index in healthy adults. Neuropsychobiology 2006 53 : 153 156.
-
(2006)
Neuropsychobiology
, vol.53
, pp. 153-156
-
-
Gunstad, J.1
Schofield, P.2
Paul, R.H.3
Spitznagel, M.B.4
Cohen, R.A.5
Williams, L.M.6
Kohn, M.7
Gordon, E.8
-
28
-
-
51849117596
-
Association of the BDNF Val66Met variation with obesity in women
-
Beckers S, Peeters A, Zegers D, Mertens I, Gaal LV, Van Hul W. Association of the BDNF Val66Met variation with obesity in women. Mol Genet Metab 2008 95 : 110 112.
-
(2008)
Mol Genet Metab
, vol.95
, pp. 110-112
-
-
Beckers, S.1
Peeters, A.2
Zegers, D.3
Mertens, I.4
Gaal, L.V.5
Van Hul, W.6
-
29
-
-
37349093727
-
A DRD4/BDNF gene-gene interaction associated with maximum BMI in women with bulimia nervosa
-
Kaplan AS, Levitan RD, Yilmaz Z, Davis C, Tharmalingam S, Kennedy JL. A DRD4/BDNF gene-gene interaction associated with maximum BMI in women with bulimia nervosa. Int J Eat Disord 2008 41 : 22 28.
-
(2008)
Int J Eat Disord
, vol.41
, pp. 22-28
-
-
Kaplan, A.S.1
Levitan, R.D.2
Yilmaz, Z.3
Davis, C.4
Tharmalingam, S.5
Kennedy, J.L.6
-
30
-
-
65649090151
-
Association of the -243 A->G polymorphism of the glutamate decarboxylase 2 gene with obesity in girls with premature pubarche
-
doi: 10.1016/j.fertnstert.2008.01.085).
-
Witchel SF, White C, Libman I. Association of the -243 A->G polymorphism of the glutamate decarboxylase 2 gene with obesity in girls with premature pubarche. Fertil Steril 2008 (doi: 10.1016/j.fertnstert.2008.01.085).
-
(2008)
Fertil Steril
-
-
Witchel, S.F.1
White, C.2
Libman, I.3
-
31
-
-
36749034255
-
Serotonin receptor 2A (HTR2A) gene polymorphisms are associated with blood pressure, central adiposity, and the metabolic syndrome
-
Halder I, Muldoon MF, Ferrell RE, Manuck SB. Serotonin receptor 2A (HTR2A) gene polymorphisms are associated with blood pressure, central adiposity, and the metabolic syndrome. Metab Syndr Relat Disord 2007 5 : 323 330.
-
(2007)
Metab Syndr Relat Disord
, vol.5
, pp. 323-330
-
-
Halder, I.1
Muldoon, M.F.2
Ferrell, R.E.3
Manuck, S.B.4
-
32
-
-
39749142748
-
Impact of the -1438G>a polymorphism in the serotonin 2A receptor gene on anthropometric profile and obesity risk: A case-control study in a Spanish Mediterranean population
-
Sorli JV, Frances F, Gonzalez JI, Guillen M, Portoles O, Sabater A, Coltell O, Corella D. Impact of the -1438G>a polymorphism in the serotonin 2A receptor gene on anthropometric profile and obesity risk: a case-control study in a Spanish Mediterranean population. Appetite 2008 50 : 260 265.
-
(2008)
Appetite
, vol.50
, pp. 260-265
-
-
Sorli, J.V.1
Frances, F.2
Gonzalez, J.I.3
Guillen, M.4
Portoles, O.5
Sabater, A.6
Coltell, O.7
Corella, D.8
-
33
-
-
34249666244
-
Leptin receptor genotype at Gln223Arg is associated with body composition, BMD, and vertebral fracture in postmenopausal Danish women
-
Fairbrother UL, Tanko LB, Walley AJ, Christiansen C, Froguel P, Blakemore AI. Leptin receptor genotype at Gln223Arg is associated with body composition, BMD, and vertebral fracture in postmenopausal Danish women. J Bone Miner Res 2007 22 : 544 550.
-
(2007)
J Bone Miner Res
, vol.22
, pp. 544-550
-
-
Fairbrother, U.L.1
Tanko, L.B.2
Walley, A.J.3
Christiansen, C.4
Froguel, P.5
Blakemore, A.I.6
-
34
-
-
33746126567
-
P.Q223R leptin receptor polymorphism associated with obesity in Brazilian multiethnic subjects
-
Duarte SF, Francischetti EA, Genelhu-Abreu V, Barroso SG, Braga JU, Cabello PH, Pimentel MM. p.Q223R leptin receptor polymorphism associated with obesity in Brazilian multiethnic subjects. Am J Hum Biol 2006 18 : 448 453.
-
(2006)
Am J Hum Biol
, vol.18
, pp. 448-453
-
-
Duarte, S.F.1
Francischetti, E.A.2
Genelhu-Abreu, V.3
Barroso, S.G.4
Braga, J.U.5
Cabello, P.H.6
Pimentel, M.M.7
-
35
-
-
33749616410
-
Effect of genetic variation in the leptin gene promoter and the leptin receptor gene on obesity risk in a population-based case-control study in Spain
-
Portoles O, Sorli JV, Frances F, Coltell O, Gonzalez JI, Saiz C, Corella D. Effect of genetic variation in the leptin gene promoter and the leptin receptor gene on obesity risk in a population-based case-control study in Spain. Eur J Epidemiol 2006 21 : 605 612.
-
(2006)
Eur J Epidemiol
, vol.21
, pp. 605-612
-
-
Portoles, O.1
Sorli, J.V.2
Frances, F.3
Coltell, O.4
Gonzalez, J.I.5
Saiz, C.6
Corella, D.7
-
36
-
-
31544469841
-
Polymorphisms in the leptin receptor (LEPR) - Putative association with obesity and T2DM
-
Park KS, Shin HD, Park BL, Cheong HS, Cho YM, Lee HK, Lee JY, Lee JK, Oh B, Kimm K. Polymorphisms in the leptin receptor (LEPR) - putative association with obesity and T2DM. J Hum Genet 2006 51 : 85 91.
-
(2006)
J Hum Genet
, vol.51
, pp. 85-91
-
-
Park, K.S.1
Shin, H.D.2
Park, B.L.3
Cheong, H.S.4
Cho, Y.M.5
Lee, H.K.6
Lee, J.Y.7
Lee, J.K.8
Oh, B.9
Kimm, K.10
-
37
-
-
47149112799
-
Genetic variations in the leptin and leptin receptor genes are associated with type 2 diabetes mellitus and metabolic traits in the Korean female population
-
Han HR, Ryu HJ, Cha HS, Go MJ, Ahn Y, Koo BK, Cho YM, Lee HK, Cho NH, Shin C, Shin HD, Kimm K, Kim HL, Oh B, Park KS. Genetic variations in the leptin and leptin receptor genes are associated with type 2 diabetes mellitus and metabolic traits in the Korean female population. Clin Genet 2008 74 : 105 115.
-
(2008)
Clin Genet
, vol.74
, pp. 105-115
-
-
Han, H.R.1
Ryu, H.J.2
Cha, H.S.3
Go, M.J.4
Ahn, Y.5
Koo, B.K.6
Cho, Y.M.7
Lee, H.K.8
Cho, N.H.9
Shin, C.10
Shin, H.D.11
Kimm, K.12
Kim, H.L.13
Oh, B.14
Park, K.S.15
-
38
-
-
33947581477
-
LEPR, ADBR3, IRS-1 and 5-HTT genes polymorphisms do not associate with obesity
-
Mergen H, Karaaslan C, Mergen M, Deniz Ozsoy E, Ozata M. LEPR, ADBR3, IRS-1 and 5-HTT genes polymorphisms do not associate with obesity. Endocr J 2007 54 : 89 94.
-
(2007)
Endocr J
, vol.54
, pp. 89-94
-
-
Mergen, H.1
Karaaslan, C.2
Mergen, M.3
Deniz Ozsoy, E.4
Ozata, M.5
-
39
-
-
33744470566
-
The Gln223Arg polymorphism in the leptin receptor is associated with familial combined hyperlipidemia
-
van der Vleuten GM, Kluijtmans LA, Hijmans A, Blom HJ, Stalenhoef AF, de Graaf J. The Gln223Arg polymorphism in the leptin receptor is associated with familial combined hyperlipidemia. Int J Obes (Lond) 2006 30 : 892 898.
-
(2006)
Int J Obes (Lond)
, vol.30
, pp. 892-898
-
-
Van Der Vleuten, G.M.1
Kluijtmans, L.A.2
Hijmans, A.3
Blom, H.J.4
Stalenhoef, A.F.5
De Graaf, J.6
-
40
-
-
33748194234
-
G-2548A polymorphism of the leptin gene is correlated with extreme obesity in Taiwanese aborigines
-
Wang TN, Huang MC, Chang WT, Ko AM, Tsai EM, Liu CS, Lee CH, Ko YC. G-2548A polymorphism of the leptin gene is correlated with extreme obesity in Taiwanese aborigines. Obesity (Silver Spring) 2006 14 : 183 187.
-
(2006)
Obesity (Silver Spring)
, vol.14
, pp. 183-187
-
-
Wang, T.N.1
Huang, M.C.2
Chang, W.T.3
Ko, A.M.4
Tsai, E.M.5
Liu, C.S.6
Lee, C.H.7
Ko, Y.C.8
-
41
-
-
34748889913
-
Candidate genes and growth curves for adiposity in African- and European-American youth
-
Podolsky RH, Barbeau P, Kang HS, Zhu H, Treiber FA, Snieder H. Candidate genes and growth curves for adiposity in African- and European-American youth. Int J Obes (Lond) 2007 31 : 1491 1499.
-
(2007)
Int J Obes (Lond)
, vol.31
, pp. 1491-1499
-
-
Podolsky, R.H.1
Barbeau, P.2
Kang, H.S.3
Zhu, H.4
Treiber, F.A.5
Snieder, H.6
-
42
-
-
39449108661
-
Association of the MC4R V103I polymorphism with the metabolic syndrome: The KORA study
-
Heid IM, Vollmert C, Kronenberg F, Huth C, Ankerst DP, Luchner A, Hinney A, Bronner G, Wichmann HE, Illig T, Doring A, Hebebrand J. Association of the MC4R V103I polymorphism with the metabolic syndrome: the KORA study. Obesity (Silver Spring) 2008 16 : 369 376.
-
(2008)
Obesity (Silver Spring)
, vol.16
, pp. 369-376
-
-
Heid, I.M.1
Vollmert, C.2
Kronenberg, F.3
Huth, C.4
Ankerst, D.P.5
Luchner, A.6
Hinney, A.7
Bronner, G.8
Wichmann, H.E.9
Illig, T.10
Doring, A.11
Hebebrand, J.12
-
43
-
-
34547839796
-
Non-synonymous polymorphisms in melanocortin-4 receptor protect against obesity: The two facets of a Janus obesity gene
-
Stutzmann F, Vatin V, Cauchi S, Morandi A, Jouret B, Landt O, Tounian P, Levy-Marchal C, Buzzetti R, Pinelli L, Balkau B, Horber F, Bougneres P, Froguel P, Meyre D. Non-synonymous polymorphisms in melanocortin-4 receptor protect against obesity: the two facets of a Janus obesity gene. Hum Mol Genet 2007 16 : 1837 1844.
-
(2007)
Hum Mol Genet
, vol.16
, pp. 1837-1844
-
-
Stutzmann, F.1
Vatin, V.2
Cauchi, S.3
Morandi, A.4
Jouret, B.5
Landt, O.6
Tounian, P.7
Levy-Marchal, C.8
Buzzetti, R.9
Pinelli, L.10
Balkau, B.11
Horber, F.12
Bougneres, P.13
Froguel, P.14
Meyre, D.15
-
44
-
-
34347393306
-
Genetic variation and decreased risk for obesity in the atherosclerosis risk in communities study
-
Hart Sailors ML, Folsom AR, Ballantyne CM, Hoelscher DM, Jackson AS, Linda Kao WH, Pankow JS, Bray MS. Genetic variation and decreased risk for obesity in the atherosclerosis risk in communities study. Diabetes Obes Metab 2007 9 : 548 557.
-
(2007)
Diabetes Obes Metab
, vol.9
, pp. 548-557
-
-
Hart Sailors, M.L.1
Folsom, A.R.2
Ballantyne, C.M.3
Hoelscher, D.M.4
Jackson, A.S.5
Linda Kao, W.H.6
Pankow, J.S.7
Bray, M.S.8
-
45
-
-
33646404622
-
Melanocortin 4 receptor mutations in a large cohort of severely obese adults: Prevalence, functional classification, genotype-phenotype relationship, and lack of association with binge eating
-
Lubrano-Berthelier C, Dubern B, Lacorte JM, Picard F, Shapiro A, Zhang S, Bertrais S, Hercberg S, Basdevant A, Clement K, Vaisse C. Melanocortin 4 receptor mutations in a large cohort of severely obese adults: prevalence, functional classification, genotype-phenotype relationship, and lack of association with binge eating. J Clin Endocrinol Metab 2006 91 : 1811 1818.
-
(2006)
J Clin Endocrinol Metab
, vol.91
, pp. 1811-1818
-
-
Lubrano-Berthelier, C.1
Dubern, B.2
Lacorte, J.M.3
Picard, F.4
Shapiro, A.5
Zhang, S.6
Bertrais, S.7
Hercberg, S.8
Basdevant, A.9
Clement, K.10
Vaisse, C.11
-
46
-
-
33646423288
-
Prevalence, spectrum, and functional characterization of melanocortin-4 receptor gene mutations in a representative population-based sample and obese adults from Germany
-
Hinney A, Bettecken T, Tarnow P, Brumm H, Reichwald K, Lichtner P, Scherag A, Nguyen TT, Schlumberger P, Rief W, Vollmert C, Illig T, Wichmann HE, Schafer H, Platzer M, Biebermann H, Meitinger T, Hebebrand J. Prevalence, spectrum, and functional characterization of melanocortin-4 receptor gene mutations in a representative population-based sample and obese adults from Germany. J Clin Endocrinol Metab 2006 91 : 1761 1769.
-
(2006)
J Clin Endocrinol Metab
, vol.91
, pp. 1761-1769
-
-
Hinney, A.1
Bettecken, T.2
Tarnow, P.3
Brumm, H.4
Reichwald, K.5
Lichtner, P.6
Scherag, A.7
Nguyen, T.T.8
Schlumberger, P.9
Rief, W.10
Vollmert, C.11
Illig, T.12
Wichmann, H.E.13
Schafer, H.14
Platzer, M.15
Biebermann, H.16
Meitinger, T.17
Hebebrand, J.18
-
47
-
-
33746040561
-
Identification and functional characterization of three novel human melanocortin-4 receptor gene variants in an obese Chinese population
-
Rong R, Tao YX, Cheung BM, Xu A, Cheung GC, Lam KS. Identification and functional characterization of three novel human melanocortin-4 receptor gene variants in an obese Chinese population. Clin Endocrinol (Oxf) 2006 65 : 198 205.
-
(2006)
Clin Endocrinol (Oxf)
, vol.65
, pp. 198-205
-
-
Rong, R.1
Tao, Y.X.2
Cheung, B.M.3
Xu, A.4
Cheung, G.C.5
Lam, K.S.6
-
48
-
-
33746369734
-
A two-base deletion -439delGC in the melanocortin-4 receptor promoter associated with early-onset obesity
-
Valli-Jaakola K, Palvimo JJ, Lipsanen-Nyman M, Salomaa V, Peltonen L, Kontula K, Schalin-Jantti C. A two-base deletion -439delGC in the melanocortin-4 receptor promoter associated with early-onset obesity. Horm Res 2006 66 : 61 69.
-
(2006)
Horm Res
, vol.66
, pp. 61-69
-
-
Valli-Jaakola, K.1
Palvimo, J.J.2
Lipsanen-Nyman, M.3
Salomaa, V.4
Peltonen, L.5
Kontula, K.6
Schalin-Jantti, C.7
-
49
-
-
61849161252
-
Association of functionally significant Melanocortin-4 but not Melanocortin-3 receptor mutations with severe adult obesity in a large North-American case-control study
-
Calton MA, Ersoy BA, Zhang S, Kane JP, Malloy MJ, Pullinger CR, Bromberg Y, Pennacchio LA, Dent R, McPherson R, Ahituv N, Vaisse C. Association of functionally significant Melanocortin-4 but not Melanocortin-3 receptor mutations with severe adult obesity in a large North-American case-control study. Hum Mol Genet 2009 18 : 1140 1147.
-
(2009)
Hum Mol Genet
, vol.18
, pp. 1140-1147
-
-
Calton, M.A.1
Ersoy, B.A.2
Zhang, S.3
Kane, J.P.4
Malloy, M.J.5
Pullinger, C.R.6
Bromberg, Y.7
Pennacchio, L.A.8
Dent, R.9
McPherson, R.10
Ahituv, N.11
Vaisse, C.12
-
50
-
-
58149339706
-
Lower metabolic rate in individuals heterozygous for either a frameshift or a functional missense MC4R variant
-
Krakoff J, Ma L, Kobes S, Knowler WC, Hanson RL, Bogardus C, Baier LJ. Lower metabolic rate in individuals heterozygous for either a frameshift or a functional missense MC4R variant. Diabetes 2008 57 : 3267 3272.
-
(2008)
Diabetes
, vol.57
, pp. 3267-3272
-
-
Krakoff, J.1
Ma, L.2
Kobes, S.3
Knowler, W.C.4
Hanson, R.L.5
Bogardus, C.6
Baier, L.J.7
-
51
-
-
52749092130
-
Prevalence of melanocortin-4 receptor deficiency in Europeans and their age-dependent penetrance in multigenerational pedigrees
-
Stutzmann F, Tan K, Vatin V, Dina C, Jouret B, Tichet J, Balkau B, Potoczna N, Horber F, O'Rahilly S, Farooqi IS, Froguel P, Meyre D. Prevalence of melanocortin-4 receptor deficiency in Europeans and their age-dependent penetrance in multigenerational pedigrees. Diabetes 2008 57 : 2511 2518.
-
(2008)
Diabetes
, vol.57
, pp. 2511-2518
-
-
Stutzmann, F.1
Tan, K.2
Vatin, V.3
Dina, C.4
Jouret, B.5
Tichet, J.6
Balkau, B.7
Potoczna, N.8
Horber, F.9
O'Rahilly, S.10
Farooqi, I.S.11
Froguel, P.12
Meyre, D.13
-
52
-
-
60249096419
-
Common genetic variants at the MC4R locus are associated with obesity, but not with dietary energy intake or colorectal cancer in the Scottish population
-
Tenesa A, Campbell H, Theodoratou E, Dunlop L, Cetnarskyj R, Farrington SM, Dunlop MG. Common genetic variants at the MC4R locus are associated with obesity, but not with dietary energy intake or colorectal cancer in the Scottish population. Int J Obes (Lond) 2009 33 : 284 288.
-
(2009)
Int J Obes (Lond)
, vol.33
, pp. 284-288
-
-
Tenesa, A.1
Campbell, H.2
Theodoratou, E.3
Dunlop, L.4
Cetnarskyj, R.5
Farrington, S.M.6
Dunlop, M.G.7
-
53
-
-
62749100569
-
Variants near MC4R associate with obesity and influence obesity-related quantitative traits in a population of middle-aged people: Studies of 14 940 Danes
-
Zobel DP, Andreasen CH, Grarup N, Eiberg H, Sorensen TI, Sandbaek A, Lauritzen T, Borch-Johnsen K, Jorgensen T, Pedersen O, Hansen T. Variants near MC4R associate with obesity and influence obesity-related quantitative traits in a population of middle-aged people: studies of 14 940 Danes. Diabetes 2009 58 : 757 764.
-
(2009)
Diabetes
, vol.58
, pp. 757-764
-
-
Zobel, D.P.1
Andreasen, C.H.2
Grarup, N.3
Eiberg, H.4
Sorensen, T.I.5
Sandbaek, A.6
Lauritzen, T.7
Borch-Johnsen, K.8
Jorgensen, T.9
Pedersen, O.10
Hansen, T.11
-
54
-
-
33749141489
-
Polymorphisms in the NPY and AGRP genes and body fatness in Dutch adults
-
van Rossum CT, Pijl H, Adan RA, Hoebee B, Seidell JC. Polymorphisms in the NPY and AGRP genes and body fatness in Dutch adults. Int J Obes (Lond) 2006 30 : 1522 1528.
-
(2006)
Int J Obes (Lond)
, vol.30
, pp. 1522-1528
-
-
Van Rossum, C.T.1
Pijl, H.2
Adan, R.A.3
Hoebee, B.4
Seidell, J.C.5
-
55
-
-
58149470809
-
Neuropeptide y polymorphism significantly magnifies diabetes and cardiovascular disease risk in obesity: The Hoorn study
-
Jaakkola U, Kallio J, Heine RJ, Nijpels G, T'Hart LM, Maassen JA, Bouter LM, Stehouwer CD, Dekker JM. Neuropeptide Y polymorphism significantly magnifies diabetes and cardiovascular disease risk in obesity: the Hoorn study. Eur J Clin Nutr 2009 63 : 150 152.
-
(2009)
Eur J Clin Nutr
, vol.63
, pp. 150-152
-
-
Jaakkola, U.1
Kallio, J.2
Heine, R.J.3
Nijpels, G.4
T'Hart, L.M.5
Maassen, J.A.6
Bouter, L.M.7
Stehouwer, C.D.8
Dekker, J.M.9
-
56
-
-
54949113309
-
The common obesity variant near MC4R gene is associated with higher intakes of total energy and dietary fat, weight change and diabetes risk in women
-
Qi L, Kraft P, Hunter DJ, Hu FB. The common obesity variant near MC4R gene is associated with higher intakes of total energy and dietary fat, weight change and diabetes risk in women. Hum Mol Genet 2008 17 : 3502 3508.
-
(2008)
Hum Mol Genet
, vol.17
, pp. 3502-3508
-
-
Qi, L.1
Kraft, P.2
Hunter, D.J.3
Hu, F.B.4
-
57
-
-
34248154742
-
Association studies of BMI and type 2 diabetes in the neuropeptide y pathway: A possible role for NPY2R as a candidate gene for type 2 diabetes in men
-
Campbell CD, Lyon HN, Nemesh J, Drake JA, Tuomi T, Gaudet D, Zhu X, Cooper RS, Ardlie KG, Groop LC, Hirschhorn JN. Association studies of BMI and type 2 diabetes in the neuropeptide Y pathway: a possible role for NPY2R as a candidate gene for type 2 diabetes in men. Diabetes 2007 56 : 1460 1467.
-
(2007)
Diabetes
, vol.56
, pp. 1460-1467
-
-
Campbell, C.D.1
Lyon, H.N.2
Nemesh, J.3
Drake, J.A.4
Tuomi, T.5
Gaudet, D.6
Zhu, X.7
Cooper, R.S.8
Ardlie, K.G.9
Groop, L.C.10
Hirschhorn, J.N.11
-
58
-
-
33846784878
-
Single nucleotide polymorphisms in the neuropeptide Y2 receptor (NPY2R) gene and association with severe obesity in French white subjects
-
Siddiq A, Gueorguiev M, Samson C, Hercberg S, Heude B, Levy-Marchal C, Jouret B, Weill J, Meyre D, Walley A, Froguel P. Single nucleotide polymorphisms in the neuropeptide Y2 receptor (NPY2R) gene and association with severe obesity in French white subjects. Diabetologia 2007 50 : 574 584.
-
(2007)
Diabetologia
, vol.50
, pp. 574-584
-
-
Siddiq, A.1
Gueorguiev, M.2
Samson, C.3
Hercberg, S.4
Heude, B.5
Levy-Marchal, C.6
Jouret, B.7
Weill, J.8
Meyre, D.9
Walley, A.10
Froguel, P.11
-
59
-
-
33749844675
-
Variants in the 5′ region of the neuropeptide y receptor Y2 gene (NPY2R) are associated with obesity in 5971 white subjects
-
Torekov SS, Larsen LH, Andersen G, Albrechtsen A, Glumer C, Borch-Johnsen K, Jorgensen T, Hansen T, Pedersen O. Variants in the 5′ region of the neuropeptide Y receptor Y2 gene (NPY2R) are associated with obesity in 5971 white subjects. Diabetologia 2006 49 : 2653 2658.
-
(2006)
Diabetologia
, vol.49
, pp. 2653-2658
-
-
Torekov, S.S.1
Larsen, L.H.2
Andersen, G.3
Albrechtsen, A.4
Glumer, C.5
Borch-Johnsen, K.6
Jorgensen, T.7
Hansen, T.8
Pedersen, O.9
-
60
-
-
33644625994
-
Common neuropeptide Y2 receptor gene variant is protective against obesity among Swedish men
-
Lavebratt C, Alpman A, Persson B, Arner P, Hoffstedt J. Common neuropeptide Y2 receptor gene variant is protective against obesity among Swedish men. Int J Obes (Lond) 2006 30 : 453 459.
-
(2006)
Int J Obes (Lond)
, vol.30
, pp. 453-459
-
-
Lavebratt, C.1
Alpman, A.2
Persson, B.3
Arner, P.4
Hoffstedt, J.5
-
61
-
-
33645089926
-
A role for beta-melanocyte-stimulating hormone in human body-weight regulation
-
Biebermann H, Castaneda TR, van Landeghem F, von Deimling A, Escher F, Brabant G, Hebebrand J, Hinney A, Tschop MH, Gruters A, Krude H. A role for beta-melanocyte-stimulating hormone in human body-weight regulation. Cell Metab 2006 3 : 141 146.
-
(2006)
Cell Metab
, vol.3
, pp. 141-146
-
-
Biebermann, H.1
Castaneda, T.R.2
Van Landeghem, F.3
Von Deimling, A.4
Escher, F.5
Brabant, G.6
Hebebrand, J.7
Hinney, A.8
Tschop, M.H.9
Gruters, A.10
Krude, H.11
-
62
-
-
33645048441
-
A POMC variant implicates beta-melanocyte-stimulating hormone in the control of human energy balance
-
Lee YS, Challis BG, Thompson DA, Yeo GS, Keogh JM, Madonna ME, Wraight V, Sims M, Vatin V, Meyre D, Shield J, Burren C, Ibrahim Z, Cheetham T, Swift P, Blackwood A, Hung CC, Wareham NJ, Froguel P, Millhauser GL, O'Rahilly S, Farooqi IS. A POMC variant implicates beta-melanocyte-stimulating hormone in the control of human energy balance. Cell Metab 2006 3 : 135 140.
-
(2006)
Cell Metab
, vol.3
, pp. 135-140
-
-
Lee, Y.S.1
Challis, B.G.2
Thompson, D.A.3
Yeo, G.S.4
Keogh, J.M.5
Madonna, M.E.6
Wraight, V.7
Sims, M.8
Vatin, V.9
Meyre, D.10
Shield, J.11
Burren, C.12
Ibrahim, Z.13
Cheetham, T.14
Swift, P.15
Blackwood, A.16
Hung, C.C.17
Wareham, N.J.18
Froguel, P.19
Millhauser, G.L.20
O'Rahilly, S.21
Farooqi, I.S.22
more..
-
63
-
-
33749549273
-
Association of genetic variation within UBL5 with phenotypes of metabolic syndrome
-
Bozaoglu K, Curran JE, Elliott KS, Walder KR, Dyer TD, Rainwater DL, VandeBerg JL, Comuzzie AG, Collier GR, Zimmet P, MacCluer JW, Jowett JB, Blangero J. Association of genetic variation within UBL5 with phenotypes of metabolic syndrome. Hum Biol 2006 78 : 147 159.
-
(2006)
Hum Biol
, vol.78
, pp. 147-159
-
-
Bozaoglu, K.1
Curran, J.E.2
Elliott, K.S.3
Walder, K.R.4
Dyer, T.D.5
Rainwater, D.L.6
Vandeberg, J.L.7
Comuzzie, A.G.8
Collier, G.R.9
Zimmet, P.10
MacCluer, J.W.11
Jowett, J.B.12
Blangero, J.13
-
64
-
-
33748316505
-
Significant linkage of BMI to chromosome 10p in the U.K. population and evaluation of GAD2 as a positional candidate
-
Groves CJ, Zeggini E, Walker M, Hitman GA, Levy JC, O'Rahilly S, Hattersley AT, McCarthy MI, Wiltshire S. Significant linkage of BMI to chromosome 10p in the U.K. population and evaluation of GAD2 as a positional candidate. Diabetes 2006 55 : 1884 1889.
-
(2006)
Diabetes
, vol.55
, pp. 1884-1889
-
-
Groves, C.J.1
Zeggini, E.2
Walker, M.3
Hitman, G.A.4
Levy, J.C.5
O'Rahilly, S.6
Hattersley, A.T.7
McCarthy, M.I.8
Wiltshire, S.9
-
65
-
-
34347333548
-
243A→G polymorphism upstream of the gene encoding GAD65 associates with lower levels of body mass index and glycaemia in a population-based sample of 5857 middle-aged White subjects
-
Boesgaard TW, Castella SI, Andersen G, Albrechtsen A, Sparso T, Borch-Johnsen K, Jorgensen T, Hansen T, Pedersen OA. 243A→G polymorphism upstream of the gene encoding GAD65 associates with lower levels of body mass index and glycaemia in a population-based sample of 5857 middle-aged White subjects. Diabet Med 2007 24 : 702 706.
-
(2007)
Diabet Med
, vol.24
, pp. 702-706
-
-
Boesgaard, T.W.1
Castella, S.I.2
Andersen, G.3
Albrechtsen, A.4
Sparso, T.5
Borch-Johnsen, K.6
Jorgensen, T.7
Hansen, T.8
Pedersen, O.A.9
-
66
-
-
48249100977
-
Association of FTO with obesity-related traits in the Cebu longitudinal health and nutrition survey (CLHNS) cohort
-
Marvelle AF, Lange LA, Qin L, Adair LS, Mohlke KL. Association of FTO with obesity-related traits in the Cebu longitudinal health and nutrition survey (CLHNS) cohort. Diabetes 2008 57 : 1987 1991.
-
(2008)
Diabetes
, vol.57
, pp. 1987-1991
-
-
Marvelle, A.F.1
Lange, L.A.2
Qin, L.3
Adair, L.S.4
Mohlke, K.L.5
-
67
-
-
42249085571
-
Influence of Lys656Asn polymorphism of the leptin receptor gene on insulin resistance in nondiabetic obese patients
-
DOI 10.1016/j.jdiacomp.2006.10.006, PII S1056872706001139
-
de Luis DA, Gonzalez Sagrado M, Aller R, Izaola O, Conde R. Influence of Lys656Asn polymorphism of the leptin receptor gene on insulin resistance in nondiabetic obese patients. J Diabetes Complications 2008 22 : 199 204. (Pubitemid 351545844)
-
(2008)
Journal of Diabetes and its Complications
, vol.22
, Issue.3
, pp. 199-204
-
-
De Luis, D.A.1
Gonzalez Sagrado, M.2
Aller, R.3
Izaola, O.4
Conde, R.5
-
68
-
-
56749156945
-
Anthropometry, carbohydrate and lipid metabolism in the East Flanders prospective twin survey: Linkage of candidate genes using two sib-pair based variance components analyses
-
Souren NY, Zeegers MP, Janssen RG, Steyls A, Gielen M, Loos RJ, Beunen G, Fagard R, Stassen AP, Aerssens J, Derom C, Vlietinck R, Paulussen AD. Anthropometry, carbohydrate and lipid metabolism in the East Flanders prospective twin survey: linkage of candidate genes using two sib-pair based variance components analyses. Twin Res Hum Genet 2008 11 : 505 516.
-
(2008)
Twin Res Hum Genet
, vol.11
, pp. 505-516
-
-
Souren, N.Y.1
Zeegers, M.P.2
Janssen, R.G.3
Steyls, A.4
Gielen, M.5
Loos, R.J.6
Beunen, G.7
Fagard, R.8
Stassen, A.P.9
Aerssens, J.10
Derom, C.11
Vlietinck, R.12
Paulussen, A.D.13
-
69
-
-
32544452700
-
The 103I variant of the melanocortin 4 receptor is associated with low serum triglyceride levels
-
Bronner G, Sattler AM, Hinney A, Soufi M, Geller F, Schafer H, Maisch B, Hebebrand J, Schaefer JR. The 103I variant of the melanocortin 4 receptor is associated with low serum triglyceride levels. J Clin Endocrinol Metab 2006 91 : 535 538.
-
(2006)
J Clin Endocrinol Metab
, vol.91
, pp. 535-538
-
-
Bronner, G.1
Sattler, A.M.2
Hinney, A.3
Soufi, M.4
Geller, F.5
Schafer, H.6
Maisch, B.7
Hebebrand, J.8
Schaefer, J.R.9
-
70
-
-
33846489214
-
Several mutations in the melanocortin 4 receptor gene are associated with obesity in Chinese children and adolescents
-
Wang CL, Liang L, Wang HJ, Fu JF, Hebebrand J, Hinney A. Several mutations in the melanocortin 4 receptor gene are associated with obesity in Chinese children and adolescents. J Endocrinol Invest 2006 29 : 894 898.
-
(2006)
J Endocrinol Invest
, vol.29
, pp. 894-898
-
-
Wang, C.L.1
Liang, L.2
Wang, H.J.3
Fu, J.F.4
Hebebrand, J.5
Hinney, A.6
-
71
-
-
51749121252
-
Association of the melanocortin-4 receptor V103I polymorphism with dietary intake in severely obese persons
-
Pichler M, Kollerits B, Heid IM, Hunt SC, Adams TD, Hopkins PN, Kronenberg F. Association of the melanocortin-4 receptor V103I polymorphism with dietary intake in severely obese persons. Am J Clin Nutr 2008 88 : 797 800.
-
(2008)
Am J Clin Nutr
, vol.88
, pp. 797-800
-
-
Pichler, M.1
Kollerits, B.2
Heid, I.M.3
Hunt, S.C.4
Adams, T.D.5
Hopkins, P.N.6
Kronenberg, F.7
-
72
-
-
33751531822
-
Nutrient intake, weight, and Leu7Pro polymorphism in prepro-neuropeptide y in children
-
Karvonen MK, Ruottinen S, Koulu M, Pesonen U, Niinikoski H, Rask-Nissila L, Simell O, Ronnemaa T. Nutrient intake, weight, and Leu7Pro polymorphism in prepro-neuropeptide Y in children. J Clin Endocrinol Metab 2006 91 : 4664 4668.
-
(2006)
J Clin Endocrinol Metab
, vol.91
, pp. 4664-4668
-
-
Karvonen, M.K.1
Ruottinen, S.2
Koulu, M.3
Pesonen, U.4
Niinikoski, H.5
Rask-Nissila, L.6
Simell, O.7
Ronnemaa, T.8
-
73
-
-
36749010747
-
No association of sequence variants in the neuropeptide Y2 receptor (NPY2R) gene with early onset obesity in Germans
-
DOI 10.1055/s-2007-992127
-
Wang HJ, Wermter AK, Nguyen TT, Scherag A, Reichwald K, Waldenmaier B, Lichtner P, Bettecken T, Hebebrand J, Hinney A. No association of sequence variants in the neuropeptide Y2 receptor (NPY2R) gene with early onset obesity in Germans. Horm Metab Res 2007 39 : 840 844. (Pubitemid 350206909)
-
(2007)
Hormone and Metabolic Research
, vol.39
, Issue.11
, pp. 840-844
-
-
Wang, H.-J.1
Wermter, A.-K.2
Nguyen, T.T.3
Scherag, A.4
Reichwald, K.5
Waldenmaier, B.6
Lichtner, P.7
Bettecken, T.8
Hebebrand, J.9
Hinney, A.10
-
74
-
-
39949083566
-
Major gender difference in association of FTO gene variant among severely obese children with obesity and obesity related phenotypes
-
Jacobsson JA, Danielsson P, Svensson V, Klovins J, Gyllensten U, Marcus C, Schioth HB, Fredriksson R. Major gender difference in association of FTO gene variant among severely obese children with obesity and obesity related phenotypes. Biochem Biophys Res Commun 2008 368 : 476 482.
-
(2008)
Biochem Biophys Res Commun
, vol.368
, pp. 476-482
-
-
Jacobsson, J.A.1
Danielsson, P.2
Svensson, V.3
Klovins, J.4
Gyllensten, U.5
Marcus, C.6
Schioth, H.B.7
Fredriksson, R.8
-
75
-
-
42449153273
-
Genetic variants of FTO influence adiposity, insulin sensitivity, leptin levels, and resting metabolic rate in the Quebec family study
-
Do R, Bailey SD, Desbiens K, Belisle A, Montpetit A, Bouchard C, Perusse L, Vohl MC, Engert JC. Genetic variants of FTO influence adiposity, insulin sensitivity, leptin levels, and resting metabolic rate in the Quebec family study. Diabetes 2008 57 : 1147 1150.
-
(2008)
Diabetes
, vol.57
, pp. 1147-1150
-
-
Do, R.1
Bailey, S.D.2
Desbiens, K.3
Belisle, A.4
Montpetit, A.5
Bouchard, C.6
Perusse, L.7
Vohl, M.C.8
Engert, J.C.9
-
76
-
-
40749094439
-
Variants in the FTO gene are associated with common obesity in the Belgian population
-
Peeters A, Beckers S, Verrijken A, Roevens P, Peeters P, Van Gaal L, Van Hul W. Variants in the FTO gene are associated with common obesity in the Belgian population. Mol Genet Metab 2008 93 : 481 484.
-
(2008)
Mol Genet Metab
, vol.93
, pp. 481-484
-
-
Peeters, A.1
Beckers, S.2
Verrijken, A.3
Roevens, P.4
Peeters, P.5
Van Gaal, L.6
Van Hul, W.7
-
77
-
-
41549127655
-
Association of the FTO gene with BMI
-
Hunt SC, Stone S, Xin Y, Scherer CA, Magness CL, Iadonato SP, Hopkins PN, Adams TD. Association of the FTO gene with BMI. Obesity (Silver Spring) 2008 16 : 902 904.
-
(2008)
Obesity (Silver Spring)
, vol.16
, pp. 902-904
-
-
Hunt, S.C.1
Stone, S.2
Xin, Y.3
Scherer, C.A.4
Magness, C.L.5
Iadonato, S.P.6
Hopkins, P.N.7
Adams, T.D.8
-
78
-
-
41549129937
-
Association between the FTO rs9939609 polymorphism and the metabolic syndrome in a non-Caucasian multi-ethnic sample
-
Al-Attar SA, Pollex RL, Ban MR, Young TK, Bjerregaard P, Anand SS, Yusuf S, Zinman B, Harris SB, Hanley AJ, Connelly PW, Huff MW, Hegele RA. Association between the FTO rs9939609 polymorphism and the metabolic syndrome in a non-Caucasian multi-ethnic sample. Cardiovasc Diabetol 2008 7 : 5.
-
(2008)
Cardiovasc Diabetol
, vol.7
, pp. 5
-
-
Al-Attar, S.A.1
Pollex, R.L.2
Ban, M.R.3
Young, T.K.4
Bjerregaard, P.5
Anand, S.S.6
Yusuf, S.7
Zinman, B.8
Harris, S.B.9
Hanley, A.J.10
Connelly, P.W.11
Huff, M.W.12
Hegele, R.A.13
-
79
-
-
41149167132
-
Association of morbid obesity with FTO and INSIG2 allelic variants
-
discussion 41.
-
Chu X, Erdman R, Susek M, Gerst H, Derr K, Al-Agha M, Wood GC, Hartman C, Yeager S, Blosky MA, Krum W, Stewart WF, Carey D, Benotti P, Still CD, Gerhard GS. Association of morbid obesity with FTO and INSIG2 allelic variants. Arch Surg 2008 143 : 235 240. discussion 41.
-
(2008)
Arch Surg
, vol.143
, pp. 235-240
-
-
Chu, X.1
Erdman, R.2
Susek, M.3
Gerst, H.4
Derr, K.5
Al-Agha, M.6
Wood, G.C.7
Hartman, C.8
Yeager, S.9
Blosky, M.A.10
Krum, W.11
Stewart, W.F.12
Carey, D.13
Benotti, P.14
Still, C.D.15
Gerhard, G.S.16
-
80
-
-
40949087723
-
Association of CDKAL1, IGF2BP2, CDKN2A/B, HHEX, SLC30A8, and KCNJ11 with susceptibility to type 2 diabetes in a Japanese population
-
Omori S, Tanaka Y, Takahashi A, Hirose H, Kashiwagi A, Kaku K, Kawamori R, Nakamura Y, Maeda S. Association of CDKAL1, IGF2BP2, CDKN2A/B, HHEX, SLC30A8, and KCNJ11 with susceptibility to type 2 diabetes in a Japanese population. Diabetes 2008 57 : 791 795.
-
(2008)
Diabetes
, vol.57
, pp. 791-795
-
-
Omori, S.1
Tanaka, Y.2
Takahashi, A.3
Hirose, H.4
Kashiwagi, A.5
Kaku, K.6
Kawamori, R.7
Nakamura, Y.8
Maeda, S.9
-
81
-
-
39749116842
-
FTO gene SNPs associated with extreme obesity in cases, controls and extremely discordant sister pairs
-
Price RA, Li WD, Zhao H. FTO gene SNPs associated with extreme obesity in cases, controls and extremely discordant sister pairs. BMC Med Genet 2008 9 : 4.
-
(2008)
BMC Med Genet
, vol.9
, pp. 4
-
-
Price, R.A.1
Li, W.D.2
Zhao, H.3
-
82
-
-
38449098674
-
Low physical activity accentuates the effect of the FTO rs9939609 polymorphism on body fat accumulation
-
Andreasen CH, Stender-Petersen KL, Mogensen MS, Torekov SS, Wegner L, Andersen G, Nielsen AL, Albrechtsen A, Borch-Johnsen K, Rasmussen SS, Clausen JO, Sandbaek A, Lauritzen T, Hansen L, Jorgensen T, Pedersen O, Hansen T. Low physical activity accentuates the effect of the FTO rs9939609 polymorphism on body fat accumulation. Diabetes 2008 57 : 95 101.
-
(2008)
Diabetes
, vol.57
, pp. 95-101
-
-
Andreasen, C.H.1
Stender-Petersen, K.L.2
Mogensen, M.S.3
Torekov, S.S.4
Wegner, L.5
Andersen, G.6
Nielsen, A.L.7
Albrechtsen, A.8
Borch-Johnsen, K.9
Rasmussen, S.S.10
Clausen, J.O.11
Sandbaek, A.12
Lauritzen, T.13
Hansen, L.14
Jorgensen, T.15
Pedersen, O.16
Hansen, T.17
-
83
-
-
58149340093
-
FTO gene variant is associated with obesity: Longitudinal analyses in two cohort studies and functional test
-
Qi L, Kang K, Zhang C, van Dam RM, Kraft P, Hunter D, Lee CH, Hu FB. FTO gene variant is associated with obesity: longitudinal analyses in two cohort studies and functional test. Diabetes 2008 57 : 3145 3151.
-
(2008)
Diabetes
, vol.57
, pp. 3145-3151
-
-
Qi, L.1
Kang, K.2
Zhang, C.3
Van Dam, R.M.4
Kraft, P.5
Hunter, D.6
Lee, C.H.7
Hu, F.B.8
-
84
-
-
60349100289
-
Variant rs9939609 in the FTO gene is associated with obesity in an adult population from Spain
-
Gonzalez-Sanchez JL, Zabena C, Martinez-Larrad MT, Martinez-Calatrava MJ, Perez-Barba M, Serrano-Rios M. Variant rs9939609 in the FTO gene is associated with obesity in an adult population from Spain. Clin Endocrinol (Oxf) 2009 70 : 390 393.
-
(2009)
Clin Endocrinol (Oxf)
, vol.70
, pp. 390-393
-
-
Gonzalez-Sanchez, J.L.1
Zabena, C.2
Martinez-Larrad, M.T.3
Martinez-Calatrava, M.J.4
Perez-Barba, M.5
Serrano-Rios, M.6
-
85
-
-
55849104388
-
FTO variants are associated with obesity in the Chinese and Malay populations in Singapore
-
Tan JT, Dorajoo R, Seielstad M, Sim X, Rick OT, Seng CK, Yin WT, Saw SM, Kai CS, Aung T, Tai ES. FTO variants are associated with obesity in the Chinese and Malay populations in Singapore. Diabetes 2008 57 : 2851 2857.
-
(2008)
Diabetes
, vol.57
, pp. 2851-2857
-
-
Tan, J.T.1
Dorajoo, R.2
Seielstad, M.3
Sim, X.4
Rick, O.T.5
Seng, C.K.6
Yin, W.T.7
Saw, S.M.8
Kai, C.S.9
Aung, T.10
Tai, E.S.11
-
86
-
-
50649089800
-
Replication of genetic effects of FTO polymorphisms on BMI in a Korean population
-
Cha SW, Choi SM, Kim KS, Park BL, Kim JR, Kim JY, Shin HD. Replication of genetic effects of FTO polymorphisms on BMI in a Korean population. Obesity (Silver Spring) 2008 16 : 2187 2189.
-
(2008)
Obesity (Silver Spring)
, vol.16
, pp. 2187-2189
-
-
Cha, S.W.1
Choi, S.M.2
Kim, K.S.3
Park, B.L.4
Kim, J.R.5
Kim, J.Y.6
Shin, H.D.7
-
87
-
-
48749097565
-
Impact of variation in the FTO gene on whole body fat distribution, ectopic fat, and weight loss
-
Haupt A, Thamer C, Machann J, Kirchhoff K, Stefan N, Tschritter O, Machicao F, Schick F, Haring HU, Fritsche A. Impact of variation in the FTO gene on whole body fat distribution, ectopic fat, and weight loss. Obesity (Silver Spring) 2008 16 : 1969 1972.
-
(2008)
Obesity (Silver Spring)
, vol.16
, pp. 1969-1972
-
-
Haupt, A.1
Thamer, C.2
MacHann, J.3
Kirchhoff, K.4
Stefan, N.5
Tschritter, O.6
MacHicao, F.7
Schick, F.8
Haring, H.U.9
Fritsche, A.10
-
88
-
-
50949104331
-
Common variation in the fat mass and obesity-associated (FTO) gene confers risk of obesity and modulates BMI in the Chinese population
-
Chang YC, Liu PH, Lee WJ, Chang TJ, Jiang YD, Li HY, Kuo SS, Lee KC, Chuang LM. Common variation in the fat mass and obesity-associated (FTO) gene confers risk of obesity and modulates BMI in the Chinese population. Diabetes 2008 57 : 2245 2252.
-
(2008)
Diabetes
, vol.57
, pp. 2245-2252
-
-
Chang, Y.C.1
Liu, P.H.2
Lee, W.J.3
Chang, T.J.4
Jiang, Y.D.5
Li, H.Y.6
Kuo, S.S.7
Lee, K.C.8
Chuang, L.M.9
-
89
-
-
50449104632
-
Implication of genetic variants near TCF7L2, SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, and FTO in type 2 diabetes and obesity in 6,719 Asians
-
Ng MC, Park KS, Oh B, Tam CH, Cho YM, Shin HD, Lam VK, Ma RC, So WY, Cho YS, Kim HL, Lee HK, Chan JC, Cho NH. Implication of genetic variants near TCF7L2, SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, and FTO in type 2 diabetes and obesity in 6,719 Asians. Diabetes 2008 57 : 2226 2233.
-
(2008)
Diabetes
, vol.57
, pp. 2226-2233
-
-
Ng, M.C.1
Park, K.S.2
Oh, B.3
Tam, C.H.4
Cho, Y.M.5
Shin, H.D.6
Lam, V.K.7
Ma, R.C.8
So, W.Y.9
Cho, Y.S.10
Kim, H.L.11
Lee, H.K.12
Chan, J.C.13
Cho, N.H.14
-
90
-
-
43049149732
-
Genetic analysis of recently identified type 2 diabetes loci in 1638 unselected patients with type 2 diabetes and 1858 control participants from a Norwegian population-based cohort (the HUNT study)
-
Hertel JK, Johansson S, Raeder H, Midthjell K, Lyssenko V, Groop L, Molven A, Njolstad PR. Genetic analysis of recently identified type 2 diabetes loci in 1638 unselected patients with type 2 diabetes and 1858 control participants from a Norwegian population-based cohort (the HUNT study). Diabetologia 2008 51 : 971 977.
-
(2008)
Diabetologia
, vol.51
, pp. 971-977
-
-
Hertel, J.K.1
Johansson, S.2
Raeder, H.3
Midthjell, K.4
Lyssenko, V.5
Groop, L.6
Molven, A.7
Njolstad, P.R.8
-
91
-
-
44349129013
-
Variations in the FTO gene are associated with severe obesity in the Japanese
-
Hotta K, Nakata Y, Matsuo T, Kamohara S, Kotani K, Komatsu R, Itoh N, Mineo I, Wada J, Masuzaki H, Yoneda M, Nakajima A, Miyazaki S, Tokunaga K, Kawamoto M, Funahashi T, Hamaguchi K, Yamada K, Hanafusa T, Oikawa S, Yoshimatsu H, Nakao K, Sakata T, Matsuzawa Y, Tanaka K, Kamatani N, Nakamura Y. Variations in the FTO gene are associated with severe obesity in the Japanese. J Hum Genet 2008 53 : 546 553.
-
(2008)
J Hum Genet
, vol.53
, pp. 546-553
-
-
Hotta, K.1
Nakata, Y.2
Matsuo, T.3
Kamohara, S.4
Kotani, K.5
Komatsu, R.6
Itoh, N.7
Mineo, I.8
Wada, J.9
Masuzaki, H.10
Yoneda, M.11
Nakajima, A.12
Miyazaki, S.13
Tokunaga, K.14
Kawamoto, M.15
Funahashi, T.16
Hamaguchi, K.17
Yamada, K.18
Hanafusa, T.19
Oikawa, S.20
Yoshimatsu, H.21
Nakao, K.22
Sakata, T.23
Matsuzawa, Y.24
Tanaka, K.25
Kamatani, N.26
Nakamura, Y.27
more..
-
92
-
-
46249094941
-
Association analysis of the FTO gene with obesity in children of Caucasian and African ancestry reveals a common tagging SNP
-
Grant SF, Li M, Bradfield JP, Kim CE, Annaiah K, Santa E, Glessner JT, Casalunovo T, Frackelton EC, Otieno FG, Shaner JL, Smith RM, Imielinski M, Eckert AW, Chiavacci RM, Berkowitz RI, Hakonarson H. Association analysis of the FTO gene with obesity in children of Caucasian and African ancestry reveals a common tagging SNP. PLoS ONE 2008 3 : e1746.
-
(2008)
PLoS ONE
, vol.3
, pp. 1746
-
-
Grant, S.F.1
Li, M.2
Bradfield, J.P.3
Kim, C.E.4
Annaiah, K.5
Santa, E.6
Glessner, J.T.7
Casalunovo, T.8
Frackelton, E.C.9
Otieno, F.G.10
Shaner, J.L.11
Smith, R.M.12
Imielinski, M.13
Eckert, A.W.14
Chiavacci, R.M.15
Berkowitz, R.I.16
Hakonarson, H.17
-
93
-
-
57749121512
-
An obesity-associated FTO gene variant and increased energy intake in children
-
Cecil JE, Tavendale R, Watt P, Hetherington MM, Palmer CN. An obesity-associated FTO gene variant and increased energy intake in children. N Engl J Med 2008 359 : 2558 2566.
-
(2008)
N Engl J Med
, vol.359
, pp. 2558-2566
-
-
Cecil, J.E.1
Tavendale, R.2
Watt, P.3
Hetherington, M.M.4
Palmer, C.N.5
-
94
-
-
58149528039
-
Replication of the association of common rs9939609 variant of FTO with increased BMI in an Australian adult twin population but no evidence for gene by environment (G × E) interaction
-
Cornes BK, Lind PA, Medland SE, Montgomery GW, Nyholt DR, Martin NG. Replication of the association of common rs9939609 variant of FTO with increased BMI in an Australian adult twin population but no evidence for gene by environment (G × E) interaction. Int J Obes (Lond) 2009 33 : 75 79.
-
(2009)
Int J Obes (Lond)
, vol.33
, pp. 75-79
-
-
Cornes, B.K.1
Lind, P.A.2
Medland, S.E.3
Montgomery, G.W.4
Nyholt, D.R.5
Martin, N.G.6
-
95
-
-
55649096648
-
Assessing gene-treatment interactions at the FTO and INSIG2 loci on obesity-related traits in the diabetes prevention program
-
Franks PW, Jablonski KA, Delahanty LM, McAteer JB, Kahn SE, Knowler WC, Florez JC. Assessing gene-treatment interactions at the FTO and INSIG2 loci on obesity-related traits in the diabetes prevention program. Diabetologia 2008 51 : 2214 2223.
-
(2008)
Diabetologia
, vol.51
, pp. 2214-2223
-
-
Franks, P.W.1
Jablonski, K.A.2
Delahanty, L.M.3
McAteer, J.B.4
Kahn, S.E.5
Knowler, W.C.6
Florez, J.C.7
-
96
-
-
58149303021
-
Increasing heritability of BMI and stronger associations with the FTO gene over childhood
-
Haworth CM, Carnell S, Meaburn EL, Davis OS, Plomin R, Wardle J. Increasing heritability of BMI and stronger associations with the FTO gene over childhood. Obesity (Silver Spring) 2008 16 : 2663 2668.
-
(2008)
Obesity (Silver Spring)
, vol.16
, pp. 2663-2668
-
-
Haworth, C.M.1
Carnell, S.2
Meaburn, E.L.3
Davis, O.S.4
Plomin, R.5
Wardle, J.6
-
97
-
-
58149289996
-
The FTO gene and obesity in a large Eastern European population sample: The HAPIEE study
-
Hubacek JA, Bohuslavova R, Kuthanova L, Kubinova R, Peasey A, Pikhart H, Marmot MG, Bobak M. The FTO gene and obesity in a large Eastern European population sample: the HAPIEE study. Obesity (Silver Spring) 2008 16 : 2764 2766.
-
(2008)
Obesity (Silver Spring)
, vol.16
, pp. 2764-2766
-
-
Hubacek, J.A.1
Bohuslavova, R.2
Kuthanova, L.3
Kubinova, R.4
Peasey, A.5
Pikhart, H.6
Marmot, M.G.7
Bobak, M.8
-
98
-
-
56549107150
-
Novel genetic variant in FTO influences insulin levels and insulin resistance in severely obese children and adolescents
-
Jacobsson JA, Klovins J, Kapa I, Danielsson P, Svensson V, Ridderstrale M, Gyllensten U, Marcus C, Fredriksson R, Schioth HB. Novel genetic variant in FTO influences insulin levels and insulin resistance in severely obese children and adolescents. Int J Obes (Lond) 2008 32 : 1730 1735.
-
(2008)
Int J Obes (Lond)
, vol.32
, pp. 1730-1735
-
-
Jacobsson, J.A.1
Klovins, J.2
Kapa, I.3
Danielsson, P.4
Svensson, V.5
Ridderstrale, M.6
Gyllensten, U.7
Marcus, C.8
Fredriksson, R.9
Schioth, H.B.10
-
99
-
-
51849111090
-
FTO gene associated fatness in relation to body fat distribution and metabolic traits throughout a broad range of fatness
-
Kring SI, Holst C, Zimmermann E, Jess T, Berentzen T, Toubro S, Hansen T, Astrup A, Pedersen O, Sorensen TI. FTO gene associated fatness in relation to body fat distribution and metabolic traits throughout a broad range of fatness. PLoS ONE 2008 3 : e2958.
-
(2008)
PLoS ONE
, vol.3
, pp. 2958
-
-
Kring, S.I.1
Holst, C.2
Zimmermann, E.3
Jess, T.4
Berentzen, T.5
Toubro, S.6
Hansen, T.7
Astrup, A.8
Pedersen, O.9
Sorensen, T.I.10
-
100
-
-
55249098087
-
FTO polymorphisms are associated with obesity but not diabetes risk in postmenopausal women
-
Song Y, You NC, Hsu YH, Howard BV, Langer RD, Manson JE, Nathan L, Niu T, Tinkev FL, Liu S. FTO polymorphisms are associated with obesity but not diabetes risk in postmenopausal women. Obesity (Silver Spring) 2008 16 : 2472 2480.
-
(2008)
Obesity (Silver Spring)
, vol.16
, pp. 2472-2480
-
-
Song, Y.1
You, N.C.2
Hsu, Y.H.3
Howard, B.V.4
Langer, R.D.5
Manson, J.E.6
Nathan, L.7
Niu, T.8
Tinkev, F.L.9
Liu, S.10
-
101
-
-
53849111547
-
The FTO gene is associated with adulthood obesity in the Mexican population
-
Villalobos-Comparan M, Teresa Flores-Dorantes M, Teresa Villarreal-Molina M, Rodriguez-Cruz M, Garcia-Ulloa AC, Robles L, Huertas-Vazquez A, Saucedo-Villarreal N, Lopez-Alarcon M, Sanchez-Munoz F, Dominguez-Lopez A, Gutierrez-Aguilar R, Menjivar M, Coral-Vazquez R, Hernandez-Stengele G, Vital-Reyes VS, Acuna-Alonzo V, Romero-Hidalgo S, Ruiz-Gomez DG, Riano-Barros D, Herrera MF, Gomez-Perez FJ, Froguel P, Garcia-Garcia E, Teresa Tusie-Luna M, Aguilar-Salinas CA, Canizales-Quinteros S. The FTO gene is associated with adulthood obesity in the Mexican population. Obesity (Silver Spring) 2008 16 : 2296 2301.
-
(2008)
Obesity (Silver Spring)
, vol.16
, pp. 2296-2301
-
-
Villalobos-Comparan, M.1
Teresa Flores-Dorantes, M.2
Teresa Villarreal-Molina, M.3
Rodriguez-Cruz, M.4
Garcia-Ulloa, A.C.5
Robles, L.6
Huertas-Vazquez, A.7
Saucedo-Villarreal, N.8
Lopez-Alarcon, M.9
Sanchez-Munoz, F.10
Dominguez-Lopez, A.11
Gutierrez-Aguilar, R.12
Menjivar, M.13
Coral-Vazquez, R.14
Hernandez-Stengele, G.15
Vital-Reyes, V.S.16
Acuna-Alonzo, V.17
Romero-Hidalgo, S.18
Ruiz-Gomez, D.G.19
Riano-Barros, D.20
Herrera, M.F.21
Gomez-Perez, F.J.22
Froguel, P.23
Garcia-Garcia, E.24
Teresa Tusie-Luna, M.25
Aguilar-Salinas, C.A.26
Canizales-Quinteros, S.27
more..
-
102
-
-
51649128621
-
Obesity associated genetic variation in FTO is associated with diminished satiety
-
Wardle J, Carnell S, Haworth CM, Farooqi IS, O'Rahilly S, Plomin R. Obesity associated genetic variation in FTO is associated with diminished satiety. J Clin Endocrinol Metab 2008 93 : 3640 3643.
-
(2008)
J Clin Endocrinol Metab
, vol.93
, pp. 3640-3643
-
-
Wardle, J.1
Carnell, S.2
Haworth, C.M.3
Farooqi, I.S.4
O'Rahilly, S.5
Plomin, R.6
-
103
-
-
58149470594
-
FTO gene variants are strongly associated with type 2 diabetes in South Asian Indians
-
Yajnik CS, Janipalli CS, Bhaskar S, Kulkarni SR, Freathy RM, Prakash S, Mani KR, Weedon MN, Kale SD, Deshpande J, Krishnaveni GV, Veena SR, Fall CH, McCarthy MI, Frayling TM, Hattersley AT, Chandak GR. FTO gene variants are strongly associated with type 2 diabetes in South Asian Indians. Diabetologia 2009 52 : 247 252.
-
(2009)
Diabetologia
, vol.52
, pp. 247-252
-
-
Yajnik, C.S.1
Janipalli, C.S.2
Bhaskar, S.3
Kulkarni, S.R.4
Freathy, R.M.5
Prakash, S.6
Mani, K.R.7
Weedon, M.N.8
Kale, S.D.9
Deshpande, J.10
Krishnaveni, G.V.11
Veena, S.R.12
Fall, C.H.13
McCarthy, M.I.14
Frayling, T.M.15
Hattersley, A.T.16
Chandak, G.R.17
-
104
-
-
58149302895
-
The FTO obesity gene. Genotyping and gene expression analysis in morbidly obese patients
-
Zabena C, Gonzalez-Sanchez JL, Martinez-Larrad MT, Torres-Garcia A, Alvarez-Fernandez-Represa J, Corbaton-Anchuelo A, Perez-Barba M, Serrano-Rios M. The FTO obesity gene. Genotyping and gene expression analysis in morbidly obese patients. Obes Surg 2009 19 : 87 95.
-
(2009)
Obes Surg
, vol.19
, pp. 87-95
-
-
Zabena, C.1
Gonzalez-Sanchez, J.L.2
Martinez-Larrad, M.T.3
Torres-Garcia, A.4
Alvarez-Fernandez-Represa, J.5
Corbaton-Anchuelo, A.6
Perez-Barba, M.7
Serrano-Rios, M.8
-
105
-
-
63249107785
-
Association analysis of variation in/near FTO, CDKAL1, SLC30A8, HHEX, EXT2, IGF2BP2, LOC387761, and CDKN2B with type 2 diabetes and related quantitative traits in Pima Indians
-
Rong R, Hanson RL, Ortiz D, Wiedrich C, Kobes S, Knowler WC, Bogardus C, Baier LJ. Association analysis of variation in/near FTO, CDKAL1, SLC30A8, HHEX, EXT2, IGF2BP2, LOC387761, and CDKN2B with type 2 diabetes and related quantitative traits in Pima Indians. Diabetes 2009 58 : 478 488.
-
(2009)
Diabetes
, vol.58
, pp. 478-488
-
-
Rong, R.1
Hanson, R.L.2
Ortiz, D.3
Wiedrich, C.4
Kobes, S.5
Knowler, W.C.6
Bogardus, C.7
Baier, L.J.8
-
106
-
-
49349111720
-
Polymorphisms of genes coding for ghrelin and its receptor in relation to anthropometry, circulating levels of IGF-I and IGFBP-3, and breast cancer risk: A case-control study nested within the European Prospective Investigation into Cancer and Nutrition (EPIC)
-
Dossus L, McKay JD, Canzian F, Wilkening S, Rinaldi S, Biessy C, Olsen A, Tjonneland A, Jakobsen MU, Overvad K, Clavel-Chapelon F, Boutron-Ruault MC, Fournier A, Linseisen J, Lukanova A, Boeing H, Fisher E, Trichopoulou A, Georgila C, Trichopoulos D, Palli D, Krogh V, Tumino R, Vineis P, Quiros JR, Sala N, Martinez-Garcia C, Dorronsoro M, Chirlaque MD, Barricarte A, van Duijnhoven FJ, Bueno-de-Mesquita HB, van Gils CH, Peeters PH, Hallmans G, Lenner P, Bingham S, Khaw KT, Key TJ, Travis RC, Ferrari P, Jenab M, Riboli E, Kaaks R. Polymorphisms of genes coding for ghrelin and its receptor in relation to anthropometry, circulating levels of IGF-I and IGFBP-3, and breast cancer risk: a case-control study nested within the European Prospective Investigation into Cancer and Nutrition (EPIC). Carcinogenesis 2008 29 : 1360 1366.
-
(2008)
Carcinogenesis
, vol.29
, pp. 1360-1366
-
-
Dossus, L.1
McKay, J.D.2
Canzian, F.3
Wilkening, S.4
Rinaldi, S.5
Biessy, C.6
Olsen, A.7
Tjonneland, A.8
Jakobsen, M.U.9
Overvad, K.10
Clavel-Chapelon, F.11
Boutron-Ruault, M.C.12
Fournier, A.13
Linseisen, J.14
Lukanova, A.15
Boeing, H.16
Fisher, E.17
Trichopoulou, A.18
Georgila, C.19
Trichopoulos, D.20
Palli, D.21
Krogh, V.22
Tumino, R.23
Vineis, P.24
Quiros, J.R.25
Sala, N.26
Martinez-Garcia, C.27
Dorronsoro, M.28
Chirlaque, M.D.29
Barricarte, A.30
Van Duijnhoven, F.J.31
Bueno-De-Mesquita, H.B.32
Van Gils, C.H.33
Peeters, P.H.34
Hallmans, G.35
Lenner, P.36
Bingham, S.37
Khaw, K.T.38
Key, T.J.39
Travis, R.C.40
Ferrari, P.41
Jenab, M.42
Riboli, E.43
Kaaks, R.44
more..
-
107
-
-
52949122823
-
Ghrelin receptor gene polymorphisms are associated with female metabolic syndrome in Chinese population
-
Li WJ, Zhen YS, Sun K, Xue H, Song XD, Wang YB, Fan XH, Han YF, Hui RT. Ghrelin receptor gene polymorphisms are associated with female metabolic syndrome in Chinese population. Chin Med J (Engl) 2008 121 : 1666 1669.
-
(2008)
Chin Med J (Engl)
, vol.121
, pp. 1666-1669
-
-
Li, W.J.1
Zhen, Y.S.2
Sun, K.3
Xue, H.4
Song, X.D.5
Wang, Y.B.6
Fan, X.H.7
Han, Y.F.8
Hui, R.T.9
-
108
-
-
51449100773
-
Variations in the ghrelin receptor gene associate with obesity and glucose metabolism in individuals with impaired glucose tolerance
-
Mager U, Degenhardt T, Pulkkinen L, Kolehmainen M, Tolppanen AM, Lindstrom J, Eriksson JG, Carlberg C, Tuomilehto J, Uusitupa M. Variations in the ghrelin receptor gene associate with obesity and glucose metabolism in individuals with impaired glucose tolerance. PLoS ONE 2008 3 : e2941.
-
(2008)
PLoS ONE
, vol.3
, pp. 2941
-
-
Mager, U.1
Degenhardt, T.2
Pulkkinen, L.3
Kolehmainen, M.4
Tolppanen, A.M.5
Lindstrom, J.6
Eriksson, J.G.7
Carlberg, C.8
Tuomilehto, J.9
Uusitupa, M.10
-
109
-
-
53749103203
-
Ghrelin receptor gene polymorphisms and body size in children and adults
-
Garcia EA, Heude B, Petry CJ, Gueorguiev M, Hassan-Smith ZK, Spanou A, Ring SM, Dunger DB, Wareham N, Sandhu M, Ong KK, Korbonits M. Ghrelin receptor gene polymorphisms and body size in children and adults. J Clin Endocrinol Metab 2008 93 : 4158 4161.
-
(2008)
J Clin Endocrinol Metab
, vol.93
, pp. 4158-4161
-
-
Garcia, E.A.1
Heude, B.2
Petry, C.J.3
Gueorguiev, M.4
Hassan-Smith, Z.K.5
Spanou, A.6
Ring, S.M.7
Dunger, D.B.8
Wareham, N.9
Sandhu, M.10
Ong, K.K.11
Korbonits, M.12
-
110
-
-
35948978077
-
Genetic study of the melanin-concentrating hormone receptor 2 in childhood and adulthood severe obesity
-
Ghoussaini M, Vatin V, Lecoeur C, Abkevich V, Younus A, Samson C, Wachter C, Heude B, Tauber M, Tounian P, Hercberg S, Weill J, Levy-Marchal C, Le Stunff C, Bougneres P, Froguel P, Meyre D. Genetic study of the melanin-concentrating hormone receptor 2 in childhood and adulthood severe obesity. J Clin Endocrinol Metab 2007 92 : 4403 4409.
-
(2007)
J Clin Endocrinol Metab
, vol.92
, pp. 4403-4409
-
-
Ghoussaini, M.1
Vatin, V.2
Lecoeur, C.3
Abkevich, V.4
Younus, A.5
Samson, C.6
Wachter, C.7
Heude, B.8
Tauber, M.9
Tounian, P.10
Hercberg, S.11
Weill, J.12
Levy-Marchal, C.13
Le Stunff, C.14
Bougneres, P.15
Froguel, P.16
Meyre, D.17
-
111
-
-
33845509898
-
Association between neuromedin U gene variants and overweight and obesity
-
Hainerova I, Torekov SS, Ek J, Finkova M, Borch-Johnsen K, Jorgensen T, Madsen OD, Lebl J, Hansen T, Pedersen O. Association between neuromedin U gene variants and overweight and obesity. J Clin Endocrinol Metab 2006 91 : 5057 5063.
-
(2006)
J Clin Endocrinol Metab
, vol.91
, pp. 5057-5063
-
-
Hainerova, I.1
Torekov, S.S.2
Ek, J.3
Finkova, M.4
Borch-Johnsen, K.5
Jorgensen, T.6
Madsen, O.D.7
Lebl, J.8
Hansen, T.9
Pedersen, O.10
-
112
-
-
48349113289
-
Common nonsynonymous variants in PCSK1 confer risk of obesity
-
Benzinou M, Creemers JW, Choquet H, Lobbens S, Dina C, Durand E, Guerardel A, Boutin P, Jouret B, Heude B, Balkau B, Tichet J, Marre M, Potoczna N, Horber F, Le Stunff C, Czernichow S, Sandbaek A, Lauritzen T, Borch-Johnsen K, Andersen G, Kiess W, Korner A, Kovacs P, Jacobson P, Carlsson LM, Walley AJ, Jorgensen T, Hansen T, Pedersen O, Meyre D, Froguel P. Common nonsynonymous variants in PCSK1 confer risk of obesity. Nat Genet 2008 40 : 943 945.
-
(2008)
Nat Genet
, vol.40
, pp. 943-945
-
-
Benzinou, M.1
Creemers, J.W.2
Choquet, H.3
Lobbens, S.4
Dina, C.5
Durand, E.6
Guerardel, A.7
Boutin, P.8
Jouret, B.9
Heude, B.10
Balkau, B.11
Tichet, J.12
Marre, M.13
Potoczna, N.14
Horber, F.15
Le Stunff, C.16
Czernichow, S.17
Sandbaek, A.18
Lauritzen, T.19
Borch-Johnsen, K.20
Andersen, G.21
Kiess, W.22
Korner, A.23
Kovacs, P.24
Jacobson, P.25
Carlsson, L.M.26
Walley, A.J.27
Jorgensen, T.28
Hansen, T.29
Pedersen, O.30
Meyre, D.31
Froguel, P.32
more..
-
113
-
-
33644754577
-
Identification of TUB as a novel candidate gene influencing body weight in humans
-
Shiri-Sverdlov R, Custers A, van Vliet-Ostaptchouk JV, van Gorp PJ, Lindsey PJ, van Tilburg JH, Zhernakova S, Feskens EJ, van der AD, Dolle ME, van Haeften TW, Koeleman BP, Hofker MH, Wijmenga C. Identification of TUB as a novel candidate gene influencing body weight in humans. Diabetes 2006 55 : 385 389.
-
(2006)
Diabetes
, vol.55
, pp. 385-389
-
-
Shiri-Sverdlov, R.1
Custers, A.2
Van Vliet-Ostaptchouk, J.V.3
Van Gorp, P.J.4
Lindsey, P.J.5
Van Tilburg, J.H.6
Zhernakova, S.7
Feskens, E.J.8
Van Der, A.D.9
Dolle, M.E.10
Van Haeften, T.W.11
Koeleman, B.P.12
Hofker, M.H.13
Wijmenga, C.14
-
114
-
-
36649024319
-
TUB is a candidate gene for late-onset obesity in women
-
Snieder H, Wang X, Shiri-Sverdlov R, van Vliet-Ostaptchouk JV, Hofker MH, Perks U, Spector TD, O'Dell SD. TUB is a candidate gene for late-onset obesity in women. Diabetologia 2008 51 : 54 61.
-
(2008)
Diabetologia
, vol.51
, pp. 54-61
-
-
Snieder, H.1
Wang, X.2
Shiri-Sverdlov, R.3
Van Vliet-Ostaptchouk, J.V.4
Hofker, M.H.5
Perks, U.6
Spector, T.D.7
O'Dell, S.D.8
-
115
-
-
39049095315
-
Polymorphisms of the TUB gene are associated with body composition and eating behavior in middle-aged women
-
van Vliet-Ostaptchouk JV, Onland-Moret NC, Shiri-Sverdlov R, van Gorp PJ, Custers A, Peeters PH, Wijmenga C, Hofker MH, van der Schouw YT. Polymorphisms of the TUB gene are associated with body composition and eating behavior in middle-aged women. PLoS ONE 2008 3 : e1405.
-
(2008)
PLoS ONE
, vol.3
, pp. 1405
-
-
Van Vliet-Ostaptchouk, J.V.1
Onland-Moret, N.C.2
Shiri-Sverdlov, R.3
Van Gorp, P.J.4
Custers, A.5
Peeters, P.H.6
Wijmenga, C.7
Hofker, M.H.8
Van Der Schouw, Y.T.9
-
116
-
-
33744763342
-
Obesity, hyperphagia and increased metabolic efficiency in Pc1 mutant mice
-
Lloyd DJ, Bohan S, Gekakis N. Obesity, hyperphagia and increased metabolic efficiency in Pc1 mutant mice. Hum Mol Genet 2006 15 : 1884 1893.
-
(2006)
Hum Mol Genet
, vol.15
, pp. 1884-1893
-
-
Lloyd, D.J.1
Bohan, S.2
Gekakis, N.3
-
117
-
-
0035134670
-
Melanin-concentrating hormone overexpression in transgenic mice leads to obesity and insulin resistance
-
Ludwig DS, Tritos NA, Mastaitis JW, Kulkarni R, Kokkotou E, Elmquist J, Lowell B, Flier JS, Maratos-Flier E. Melanin-concentrating hormone overexpression in transgenic mice leads to obesity and insulin resistance. J Clin Invest 2001 107 : 379 386.
-
(2001)
J Clin Invest
, vol.107
, pp. 379-386
-
-
Ludwig, D.S.1
Tritos, N.A.2
Mastaitis, J.W.3
Kulkarni, R.4
Kokkotou, E.5
Elmquist, J.6
Lowell, B.7
Flier, J.S.8
Maratos-Flier, E.9
-
118
-
-
0035912709
-
Identification and characterization of a second melanin-concentrating hormone receptor, MCH-2R
-
Sailer AW, Sano H, Zeng Z, McDonald TP, Pan J, Pong SS, Feighner SD, Tan CP, Fukami T, Iwaasa H, Hreniuk DL, Morin NR, Sadowski SJ, Ito M, Bansal A, Ky B, Figueroa DJ, Jiang Q, Austin CP, MacNeil DJ, Ishihara A, Ihara M, Kanatani A, Van der Ploeg LH, Howard AD, Liu Q. Identification and characterization of a second melanin-concentrating hormone receptor, MCH-2R. Proc Natl Acad Sci USA 2001 98 : 7564 7569.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 7564-7569
-
-
Sailer, A.W.1
Sano, H.2
Zeng, Z.3
McDonald, T.P.4
Pan, J.5
Pong, S.S.6
Feighner, S.D.7
Tan, C.P.8
Fukami, T.9
Iwaasa, H.10
Hreniuk, D.L.11
Morin, N.R.12
Sadowski, S.J.13
Ito, M.14
Bansal, A.15
Ky, B.16
Figueroa, D.J.17
Jiang, Q.18
Austin, C.P.19
MacNeil, D.J.20
Ishihara, A.21
Ihara, M.22
Kanatani, A.23
Van Der Ploeg, L.H.24
Howard, A.D.25
Liu, Q.26
more..
-
119
-
-
20244375986
-
Transgenic overexpression of neuromedin U promotes leanness and hypophagia in mice
-
Kowalski TJ, Spar BD, Markowitz L, Maguire M, Golovko A, Yang S, Farley C, Cook JA, Tetzloff G, Hoos L, Del Vecchio RA, Kazdoba TM, McCool MF, Hwa JJ, Hyde LA, Davis H, Vassileva G, Hedrick JA, Gustafson EL. Transgenic overexpression of neuromedin U promotes leanness and hypophagia in mice. J Endocrinol 2005 185 : 151 164.
-
(2005)
J Endocrinol
, vol.185
, pp. 151-164
-
-
Kowalski, T.J.1
Spar, B.D.2
Markowitz, L.3
Maguire, M.4
Golovko, A.5
Yang, S.6
Farley, C.7
Cook, J.A.8
Tetzloff, G.9
Hoos, L.10
Del Vecchio, R.A.11
Kazdoba, T.M.12
McCool, M.F.13
Hwa, J.J.14
Hyde, L.A.15
Davis, H.16
Vassileva, G.17
Hedrick, J.A.18
Gustafson, E.L.19
-
120
-
-
0025627770
-
Fat (fat) and tubby (tub): Two autosomal recessive mutations causing obesity syndromes in the mouse
-
Coleman DL, Eicher EM. Fat (fat) and tubby (tub): two autosomal recessive mutations causing obesity syndromes in the mouse. J Hered 1990 81 : 424 427.
-
(1990)
J Hered
, vol.81
, pp. 424-427
-
-
Coleman, D.L.1
Eicher, E.M.2
-
122
-
-
34547831224
-
The V103I polymorphism of the MC4R gene and obesity: Population based studies and meta-analysis of 29 563 individuals
-
Young EH, Wareham NJ, Farooqi S, Hinney A, Hebebrand J, Scherag A, O'Rahilly S, Barroso I, Sandhu MS. The V103I polymorphism of the MC4R gene and obesity: population based studies and meta-analysis of 29 563 individuals. Int J Obes (Lond) 2007 31 : 1437 1441.
-
(2007)
Int J Obes (Lond)
, vol.31
, pp. 1437-1441
-
-
Young, E.H.1
Wareham, N.J.2
Farooqi, S.3
Hinney, A.4
Hebebrand, J.5
Scherag, A.6
O'Rahilly, S.7
Barroso, I.8
Sandhu, M.S.9
-
124
-
-
0242661936
-
Nonreplication in genetic association studies of obesity and diabetes research
-
Redden DT, Allison DB. Nonreplication in genetic association studies of obesity and diabetes research. J Nutr 2003 133 : 3323 3326.
-
(2003)
J Nutr
, vol.133
, pp. 3323-3326
-
-
Redden, D.T.1
Allison, D.B.2
-
125
-
-
26244444318
-
What makes a good genetic association study?
-
Hattersley AT, McCarthy MI. What makes a good genetic association study? Lancet 2005 366 : 1315 1323.
-
(2005)
Lancet
, vol.366
, pp. 1315-1323
-
-
Hattersley, A.T.1
McCarthy, M.I.2
-
126
-
-
35348983887
-
A second generation human haplotype map of over 3.1 million SNPs
-
Frazer KA, Ballinger DG, Cox DR, Hinds DA, Stuve LL, Gibbs RA, Belmont
-
(2007)
Nature
, vol.449
, pp. 851-861
-
-
Frazer, K.A.1
Ballinger, D.G.2
Cox, D.R.3
Hinds, D.A.4
Stuve, L.L.5
Gibbs, R.A.6
Belmont, J.W.7
Boudreau, A.8
Hardenbol, P.9
Leal, S.M.10
Pasternak, S.11
Wheeler, D.A.12
Willis, T.D.13
Yu, F.14
Yang, H.15
Zeng, C.16
Gao, Y.17
Hu, H.18
Hu, W.19
Li, C.20
Lin, W.21
Liu, S.22
Pan, H.23
Tang, X.24
Wang, J.25
Wang, W.26
Yu, J.27
Zhang, B.28
Zhang, Q.29
Zhao, H.30
Zhou, J.31
Gabriel, S.B.32
Barry, R.33
Blumenstiel, B.34
Camargo, A.35
Defelice, M.36
Faggart, M.37
Goyette, M.38
Gupta, S.39
Moore, J.40
Nguyen, H.41
Onofrio, R.C.42
Parkin, M.43
Roy, J.44
Stahl, E.45
Winchester, E.46
Ziaugra, L.47
Altshuler, D.48
Shen, Y.49
Yao, Z.50
Huang, W.51
Chu, X.52
He, Y.53
Jin, L.54
Liu, Y.55
Sun, W.56
Wang, H.57
Wang, Y.58
Xiong, X.59
Xu, L.60
Waye, M.M.61
Tsui, S.K.62
Xue, H.63
Wong, J.T.64
Galver, L.M.65
Fan, J.B.66
Gunderson, K.67
Murray, S.S.68
Oliphant, A.R.69
Chee, M.S.70
Montpetit, A.71
Chagnon, F.72
Ferretti, V.73
Leboeuf, M.74
Olivier, J.F.75
Phillips, M.S.76
Roumy, S.77
Sallee, C.78
Verner, A.79
Hudson, T.J.80
Kwok, P.Y.81
Cai, D.82
Koboldt, D.C.83
Miller, R.D.84
Pawlikowska, L.85
Taillon-Miller, P.86
Xiao, M.87
Tsui, L.C.88
Mak, W.89
Song, Y.Q.90
Tam, P.K.91
Nakamura, Y.92
Kawaguchi, T.93
Kitamoto, T.94
Morizono, T.95
Nagashima, A.96
Ohnishi, Y.97
Sekine, A.98
Tanaka, T.99
more..
-
127
-
-
44349166252
-
Common genetic variation near MC4R is associated with waist circumference and insulin resistance
-
Chambers JC, Elliott P, Zabaneh D, Zhang W, Li Y, Froguel P, Balding D, Scott J, Kooner JS. Common genetic variation near MC4R is associated with waist circumference and insulin resistance. Nat Genet 2008 40 : 716 718.
-
(2008)
Nat Genet
, vol.40
, pp. 716-718
-
-
Chambers, J.C.1
Elliott, P.2
Zabaneh, D.3
Zhang, W.4
Li, Y.5
Froguel, P.6
Balding, D.7
Scott, J.8
Kooner, J.S.9
-
128
-
-
34248594090
-
A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity
-
Frayling TM, Timpson NJ, Weedon MN, Zeggini E, Freathy RM, Lindgren CM, Perry JR, Elliott KS, Lango H, Rayner NW, Shields B, Harries LW, Barrett JC, Ellard S, Groves CJ, Knight B, Patch AM, Ness AR, Ebrahim S, Lawlor DA, Ring SM, Ben-Shlomo Y, Jarvelin MR, Sovio U, Bennett AJ, Melzer D, Ferrucci L, Loos RJ, Barroso I, Wareham NJ, Karpe F, Owen KR, Cardon LR, Walker M, Hitman GA, Palmer CN, Doney AS, Morris AD, Smith GD, Hattersley AT, McCarthy MI. A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science 2007 316 : 889 894.
-
(2007)
Science
, vol.316
, pp. 889-894
-
-
Frayling, T.M.1
Timpson, N.J.2
Weedon, M.N.3
Zeggini, E.4
Freathy, R.M.5
Lindgren, C.M.6
Perry, J.R.7
Elliott, K.S.8
Lango, H.9
Rayner, N.W.10
Shields, B.11
Harries, L.W.12
Barrett, J.C.13
Ellard, S.14
Groves, C.J.15
Knight, B.16
Patch, A.M.17
Ness, A.R.18
Ebrahim, S.19
Lawlor, D.A.20
Ring, S.M.21
Ben-Shlomo, Y.22
Jarvelin, M.R.23
Sovio, U.24
Bennett, A.J.25
Melzer, D.26
Ferrucci, L.27
Loos, R.J.28
Barroso, I.29
Wareham, N.J.30
Karpe, F.31
Owen, K.R.32
Cardon, L.R.33
Walker, M.34
Hitman, G.A.35
Palmer, C.N.36
Doney, A.S.37
Morris, A.D.38
Smith, G.D.39
Hattersley, A.T.40
McCarthy, M.I.41
more..
-
129
-
-
41749090524
-
Genome wide association (GWA) study for early onset extreme obesity supports the role of fat mass and obesity associated gene (FTO) variants
-
Hinney A, Nguyen TT, Scherag A, Friedel S, Bronner G, Muller TD, Grallert H, Illig T, Wichmann HE, Rief W, Schafer H, Hebebrand J. Genome wide association (GWA) study for early onset extreme obesity supports the role of fat mass and obesity associated gene (FTO) variants. PLoS ONE 2007 2 : e1361.
-
(2007)
PLoS ONE
, vol.2
, pp. 1361
-
-
Hinney, A.1
Nguyen, T.T.2
Scherag, A.3
Friedel, S.4
Bronner, G.5
Muller, T.D.6
Grallert, H.7
Illig, T.8
Wichmann, H.E.9
Rief, W.10
Schafer, H.11
Hebebrand, J.12
-
130
-
-
44349142294
-
Common variants near MC4R are associated with fat mass, weight and risk of obesity
-
Loos RJ, Lindgren CM, Li S, Wheeler E, Zhao JH, Prokopenko I, Inouye M, Freathy RM, Attwood AP, Beckmann JS, Berndt SI, Jacobs KB, Chanock SJ, Hayes RB, Bergmann S, Bennett AJ, Bingham SA, Bochud M, Brown M, Cauchi S, Connell JM, Cooper C, Smith GD, Day I, Dina C, De S, Dermitzakis ET, Doney AS, Elliott KS, Elliott P, Evans DM, Sadaf Farooqi I, Froguel P, Ghori J, Groves CJ, Gwilliam R, Hadley D, Hall AS, Hattersley AT, Hebebrand J, Heid IM, Lamina C, Gieger C, Illig T, Meitinger T, Wichmann HE, Herrera B, Hinney A, Hunt SE, Jarvelin MR, Johnson T, Jolley JD, Karpe F, Keniry A, Khaw KT, Luben RN, Mangino M, Marchini J, McArdle WL, McGinnis R, Meyre D, Munroe PB, Morris AD, Ness AR, Neville MJ, Nica AC, Ong KK, O'Rahilly S, Owen KR, Palmer CN, Papadakis K, Potter S, Pouta A, Qi L, Randall JC, Rayner NW, Ring SM, Sandhu MS, Scherag A, Sims MA, Song K, Soranzo N, Speliotes EK, Syddall HE, Teichmann SA, Timpson NJ, Tobias JH, Uda M, Vogel CI, Wallace C, Waterworth DM, Weedon MN, Willer CJ, Wraight Yuan X, Zeggini E, Hirschhorn JN, Strachan DP, Ouwehand WH, Caulfield MJ, Samani NJ, Frayling TM, Vollenweider P, Waeber G, Mooser V, Deloukas P, McCarthy MI, Wareham NJ, Barroso I, Kraft P, Hankinson SE, Hunter DJ, Hu FB, Lyon HN, Voight BF, Ridderstrale M, Groop L, Scheet P, Sanna S, Abecasis GR, Albai G, Nagaraja R, Schlessinger D, Jackson AU, Tuomilehto J, Collins FS, Boehnke M, Mohlke KL. Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet 2008 40 : 768 775.
-
(2008)
Nat Genet
, vol.40
, pp. 768-775
-
-
Loos, R.J.1
Lindgren, C.M.2
Li, S.3
Wheeler, E.4
Zhao, J.H.5
Prokopenko, I.6
Inouye, M.7
Freathy, R.M.8
Attwood, A.P.9
Beckmann, J.S.10
Berndt, S.I.11
Jacobs, K.B.12
Chanock, S.J.13
Hayes, R.B.14
Bergmann, S.15
Bennett, A.J.16
Bingham, S.A.17
Bochud, M.18
Brown, M.19
Cauchi, S.20
Connell, J.M.21
Cooper, C.22
Smith, G.D.23
Day, I.24
Dina, C.25
De, S.26
Dermitzakis, E.T.27
Doney, A.S.28
Elliott, K.S.29
Elliott, P.30
Evans, D.M.31
Sadaf Farooqi, I.32
Froguel, P.33
Ghori, J.34
Groves, C.J.35
Gwilliam, R.36
Hadley, D.37
Hall, A.S.38
Hattersley, A.T.39
Hebebrand, J.40
Heid, I.M.41
Lamina, C.42
Gieger, C.43
Illig, T.44
Meitinger, T.45
Wichmann, H.E.46
Herrera, B.47
Hinney, A.48
Hunt, S.E.49
Jarvelin, M.R.50
Johnson, T.51
Jolley, J.D.52
Karpe, F.53
Keniry, A.54
Khaw, K.T.55
Luben, R.N.56
Mangino, M.57
Marchini, J.58
McArdle, W.L.59
McGinnis, R.60
Meyre, D.61
Munroe, P.B.62
Morris, A.D.63
Ness, A.R.64
Neville, M.J.65
Nica, A.C.66
Ong, K.K.67
O'Rahilly, S.68
Owen, K.R.69
Palmer, C.N.70
Papadakis, K.71
Potter, S.72
Pouta, A.73
Qi, L.74
Randall, J.C.75
Rayner, N.W.76
Ring, S.M.77
Sandhu, M.S.78
Scherag, A.79
Sims, M.A.80
Song, K.81
Soranzo, N.82
Speliotes, E.K.83
Syddall, H.E.84
Teichmann, S.A.85
Timpson, N.J.86
Tobias, J.H.87
Uda, M.88
Vogel, C.I.89
Wallace, C.90
Waterworth, D.M.91
Weedon, M.N.92
Willer, C.J.93
Wraight, Y.X.94
Zeggini, E.95
Hirschhorn, J.N.96
Strachan, D.P.97
Ouwehand, W.H.98
Caulfield, M.J.99
more..
-
131
-
-
34249777814
-
Variation in FTO contributes to childhood obesity and severe adult obesity
-
Dina C, Meyre D, Gallina S, Durand E, Korner A, Jacobson P, Carlsson LM, Kiess W, Vatin V, Lecoeur C, Delplanque J, Vaillant E, Pattou F, Ruiz J, Weill J, Levy-Marchal C, Horber F, Potoczna N, Hercberg S, Le Stunff C, Bougneres P, Kovacs P, Marre M, Balkau B, Cauchi S, Chevre JC, Froguel P. Variation in FTO contributes to childhood obesity and severe adult obesity. Nat Genet 2007 39 : 724 726.
-
(2007)
Nat Genet
, vol.39
, pp. 724-726
-
-
Dina, C.1
Meyre, D.2
Gallina, S.3
Durand, E.4
Korner, A.5
Jacobson, P.6
Carlsson, L.M.7
Kiess, W.8
Vatin, V.9
Lecoeur, C.10
Delplanque, J.11
Vaillant, E.12
Pattou, F.13
Ruiz, J.14
Weill, J.15
Levy-Marchal, C.16
Horber, F.17
Potoczna, N.18
Hercberg, S.19
Le Stunff, C.20
Bougneres, P.21
Kovacs, P.22
Marre, M.23
Balkau, B.24
Cauchi, S.25
Chevre, J.C.26
Froguel, P.27
more..
-
132
-
-
34547625955
-
Genome-wide association scan shows genetic variants in the FTO Gene are associated with obesity-related traits
-
Scuteri A, Sanna S, Chen WM, Uda M, Albai G, Strait J, Najjar S, Nagaraja R, Orru M, Usala G, Dei M, Lai S, Maschio A, Busonero F, Mulas A, Ehret GB, Fink AA, Weder AB, Cooper RS, Galan P, Chakravarti A, Schlessinger D, Cao A, Lakatta E, Abecasis GR. Genome-wide association scan shows genetic variants in the FTO Gene are associated with obesity-related traits. PLoS Genet 2007 3 : e115.
-
(2007)
PLoS Genet
, vol.3
, pp. 115
-
-
Scuteri, A.1
Sanna, S.2
Chen, W.M.3
Uda, M.4
Albai, G.5
Strait, J.6
Najjar, S.7
Nagaraja, R.8
Orru, M.9
Usala, G.10
Dei, M.11
Lai, S.12
Maschio, A.13
Busonero, F.14
Mulas, A.15
Ehret, G.B.16
Fink, A.A.17
Weder, A.B.18
Cooper, R.S.19
Galan, P.20
Chakravarti, A.21
Schlessinger, D.22
Cao, A.23
Lakatta, E.24
Abecasis, G.R.25
more..
-
133
-
-
58149163142
-
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation
-
Willer CJ, Speliotes EK, Loos RJ, Li S, Lindgren CM, Heid IM, Berndt SI, Elliott AL, Jackson AU, Lamina C, Lettre G, Lim N, Lyon HN, McCarroll SA, Papadakis K, Qi L, Randall JC, Roccasecca RM, Sanna S, Scheet P, Weedon MN, Wheeler E, Zhao JH, Jacobs LC, Prokopenko I, Soranzo N, Tanaka T, Timpson NJ, Almgren P, Bennett A, Bergman RN, Bingham SA, Bonnycastle LL, Brown M, Burtt NP, Chines P, Coin L, Collins FS, Connell JM, Cooper C, Smith GD, Dennison EM, Deodhar P, Elliott P, Erdos MR, Estrada K, Evans DM, Gianniny L, Gieger C, Gillson CJ, Guiducci C, Hackett R, Hadley D, Hall AS, Havulinna AS, Hebebrand J, Hofman A, Isomaa B, Jacobs KB, Johnson T, Jousilahti P, Jovanovic Z, Khaw KT, Kraft P, Kuokkanen M, Kuusisto J, Laitinen J, Lakatta EG, Luan J, Luben RN, Mangino M, McArdle WL, Meitinger T, Mulas A, Munroe PB, Narisu N, Ness AR, Northstone K, O'Rahilly S, Purmann C, Rees MG, Ridderstrale M, Ring SM, Rivadeneira F, Ruokonen A, Sandhu MS, Saramies J, Scott LJ, Scuteri A, Silander K, Sims MA, Song K, Stephens J, Stevens S, Stringham HM, Tung YC, Valle TT, Van Duijn CM, Vimaleswaran KS, Vollenweider P, Waeber G, Wallace C, Watanabe RM, Waterworth DM, Watkins N, Witteman JC, Zeggini E, Zhai G, Zillikens MC, Altshuler D, Caulfield MJ, Chanock SJ, Farooqi IS, Ferrucci L, Guralnik JM, Hattersley AT, Hu FB, Jarvelin MR, Laakso M, Mooser V, Ong KK, Ouwehand WH, Salomaa V, Samani NJ, Spector TD, Tuomi T, Tuomilehto J, Uda M, Uitterlinden AG, Wareham NJ, Deloukas P, Frayling TM, Groop LC, Hayes RB, Hunter DJ, Mohlke KL, Peltonen L, Schlessinger D, Strachan DP, Wichmann HE, McCarthy MI, Boehnke M, Barroso I, Abecasis GR, Hirschhorn JN. Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet 2009 41 : 25 34.
-
(2009)
Nat Genet
, vol.41
, pp. 25-34
-
-
Willer, C.J.1
Speliotes, E.K.2
Loos, R.J.3
Li, S.4
Lindgren, C.M.5
Heid, I.M.6
Berndt, S.I.7
Elliott, A.L.8
Jackson, A.U.9
Lamina, C.10
Lettre, G.11
Lim, N.12
Lyon, H.N.13
McCarroll, S.A.14
Papadakis, K.15
Qi, L.16
Randall, J.C.17
Roccasecca, R.M.18
Sanna, S.19
Scheet, P.20
Weedon, M.N.21
Wheeler, E.22
Zhao, J.H.23
Jacobs, L.C.24
Prokopenko, I.25
Soranzo, N.26
Tanaka, T.27
Timpson, N.J.28
Almgren, P.29
Bennett, A.30
Bergman, R.N.31
Bingham, S.A.32
Bonnycastle, L.L.33
Brown, M.34
Burtt, N.P.35
Chines, P.36
Coin, L.37
Collins, F.S.38
Connell, J.M.39
Cooper, C.40
Smith, G.D.41
Dennison, E.M.42
Deodhar, P.43
Elliott, P.44
Erdos, M.R.45
Estrada, K.46
Evans, D.M.47
Gianniny, L.48
Gieger, C.49
Gillson, C.J.50
Guiducci, C.51
Hackett, R.52
Hadley, D.53
Hall, A.S.54
Havulinna, A.S.55
Hebebrand, J.56
Hofman, A.57
Isomaa, B.58
Jacobs, K.B.59
Johnson, T.60
Jousilahti, P.61
Jovanovic, Z.62
Khaw, K.T.63
Kraft, P.64
Kuokkanen, M.65
Kuusisto, J.66
Laitinen, J.67
Lakatta, E.G.68
Luan, J.69
Luben, R.N.70
Mangino, M.71
McArdle, W.L.72
Meitinger, T.73
Mulas, A.74
Munroe, P.B.75
Narisu, N.76
Ness, A.R.77
Northstone, K.78
O'Rahilly, S.79
Purmann, C.80
Rees, M.G.81
Ridderstrale, M.82
Ring, S.M.83
Rivadeneira, F.84
Ruokonen, A.85
Sandhu, M.S.86
Saramies, J.87
Scott, L.J.88
Scuteri, A.89
Silander, K.90
Sims, M.A.91
Song, K.92
Stephens, J.93
Stevens, S.94
Stringham, H.M.95
Tung, Y.C.96
Valle, T.T.97
Van Duijn, C.M.98
Vimaleswaran, K.S.99
more..
-
134
-
-
58149163141
-
Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity
-
Thorleifsson G, Walters GB, Gudbjartsson DF, Steinthorsdottir V, Sulem P, Helgadottir A, Styrkarsdottir U, Gretarsdottir S, Thorlacius S, Jonsdottir I, Jonsdottir T, Olafsdottir EJ, Olafsdottir GH, Jonsson T, Jonsson F, Borch-Johnsen K, Hansen T, Andersen G, Jorgensen T, Lauritzen T, Aben KK, Verbeek AL, Roeleveld N, Kampman E, Yanek LR, Becker LC, Tryggvadottir L, Rafnar T, Becker DM, Gulcher J, Kiemeney LA, Pedersen O, Kong A, Thorsteinsdottir U, Stefansson K. Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity. Nat Genet 2009 41 : 18 24.
-
(2009)
Nat Genet
, vol.41
, pp. 18-24
-
-
Thorleifsson, G.1
Walters, G.B.2
Gudbjartsson, D.F.3
Steinthorsdottir, V.4
Sulem, P.5
Helgadottir, A.6
Styrkarsdottir, U.7
Gretarsdottir, S.8
Thorlacius, S.9
Jonsdottir, I.10
Jonsdottir, T.11
Olafsdottir, E.J.12
Olafsdottir, G.H.13
Jonsson, T.14
Jonsson, F.15
Borch-Johnsen, K.16
Hansen, T.17
Andersen, G.18
Jorgensen, T.19
Lauritzen, T.20
Aben, K.K.21
Verbeek, A.L.22
Roeleveld, N.23
Kampman, E.24
Yanek, L.R.25
Becker, L.C.26
Tryggvadottir, L.27
Rafnar, T.28
Becker, D.M.29
Gulcher, J.30
Kiemeney, L.A.31
Pedersen, O.32
Kong, A.33
Thorsteinsdottir, U.34
Stefansson, K.35
more..
-
135
-
-
59149097625
-
Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations
-
Meyre D, Delplanque J, Chevre JC, Lecoeur C, Lobbens S, Gallina S, Durand E, Vatin V, Degraeve F, Proenca C, Gaget S, Korner A, Kovacs P, Kiess W, Tichet J, Marre M, Hartikainen AL, Horber F, Potoczna N, Hercberg S, Levy-Marchal C, Pattou F, Heude B, Tauber M, McCarthy MI, Blakemore AI, Montpetit A, Polychronakos C, Weill J, Coin LJ, Asher J, Elliott P, Jarvelin MR, Visvikis-Siest S, Balkau B, Sladek R, Balding D, Walley A, Dina C, Froguel P. Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations. Nat Genet 2009 41 : 157 159.
-
(2009)
Nat Genet
, vol.41
, pp. 157-159
-
-
Meyre, D.1
Delplanque, J.2
Chevre, J.C.3
Lecoeur, C.4
Lobbens, S.5
Gallina, S.6
Durand, E.7
Vatin, V.8
Degraeve, F.9
Proenca, C.10
Gaget, S.11
Korner, A.12
Kovacs, P.13
Kiess, W.14
Tichet, J.15
Marre, M.16
Hartikainen, A.L.17
Horber, F.18
Potoczna, N.19
Hercberg, S.20
Levy-Marchal, C.21
Pattou, F.22
Heude, B.23
Tauber, M.24
McCarthy, M.I.25
Blakemore, A.I.26
Montpetit, A.27
Polychronakos, C.28
Weill, J.29
Coin, L.J.30
Asher, J.31
Elliott, P.32
Jarvelin, M.R.33
Visvikis-Siest, S.34
Balkau, B.35
Sladek, R.36
Balding, D.37
Walley, A.38
Dina, C.39
Froguel, P.40
more..
-
136
-
-
33947525459
-
Functional single-nucleotide polymorphisms in the secretogranin III (SCG3) gene that form secretory granules with appetite-related neuropeptides are associated with obesity
-
Tanabe A, Yanagiya T, Iida A, Saito S, Sekine A, Takahashi A, Nakamura T, Tsunoda T, Kamohara S, Nakata Y, Kotani K, Komatsu R, Itoh N, Mineo I, Wada J, Funahashi T, Miyazaki S, Tokunaga K, Hamaguchi K, Shimada T, Tanaka K, Yamada K, Hanafusa T, Oikawa S, Yoshimatsu H, Sakata T, Matsuzawa Y, Kamatani N, Nakamura Y, Hotta K. Functional single-nucleotide polymorphisms in the secretogranin III (SCG3) gene that form secretory granules with appetite-related neuropeptides are associated with obesity. J Clin Endocrinol Metab 2007 92 : 1145 1154.
-
(2007)
J Clin Endocrinol Metab
, vol.92
, pp. 1145-1154
-
-
Tanabe, A.1
Yanagiya, T.2
Iida, A.3
Saito, S.4
Sekine, A.5
Takahashi, A.6
Nakamura, T.7
Tsunoda, T.8
Kamohara, S.9
Nakata, Y.10
Kotani, K.11
Komatsu, R.12
Itoh, N.13
Mineo, I.14
Wada, J.15
Funahashi, T.16
Miyazaki, S.17
Tokunaga, K.18
Hamaguchi, K.19
Shimada, T.20
Tanaka, K.21
Yamada, K.22
Hanafusa, T.23
Oikawa, S.24
Yoshimatsu, H.25
Sakata, T.26
Matsuzawa, Y.27
Kamatani, N.28
Nakamura, Y.29
Hotta, K.30
more..
-
137
-
-
36248986199
-
Association of single-nucleotide polymorphisms in MTMR9 gene with obesity
-
Yanagiya T, Tanabe A, Iida A, Saito S, Sekine A, Takahashi A, Tsunoda T, Kamohara S, Nakata Y, Kotani K, Komatsu R, Itoh N, Mineo I, Wada J, Masuzaki H, Yoneda M, Nakajima A, Miyazaki S, Tokunaga K, Kawamoto M, Funahashi T, Hamaguchi K, Tanaka K, Yamada K, Hanafusa T, Oikawa S, Yoshimatsu H, Nakao K, Sakata T, Matsuzawa Y, Kamatani N, Nakamura Y, Hotta K. Association of single-nucleotide polymorphisms in MTMR9 gene with obesity. Hum Mol Genet 2007 16 : 3017 3026.
-
(2007)
Hum Mol Genet
, vol.16
, pp. 3017-3026
-
-
Yanagiya, T.1
Tanabe, A.2
Iida, A.3
Saito, S.4
Sekine, A.5
Takahashi, A.6
Tsunoda, T.7
Kamohara, S.8
Nakata, Y.9
Kotani, K.10
Komatsu, R.11
Itoh, N.12
Mineo, I.13
Wada, J.14
Masuzaki, H.15
Yoneda, M.16
Nakajima, A.17
Miyazaki, S.18
Tokunaga, K.19
Kawamoto, M.20
Funahashi, T.21
Hamaguchi, K.22
Tanaka, K.23
Yamada, K.24
Hanafusa, T.25
Oikawa, S.26
Yoshimatsu, H.27
Nakao, K.28
Sakata, T.29
Matsuzawa, Y.30
Kamatani, N.31
Nakamura, Y.32
Hotta, K.33
more..
-
138
-
-
42249083837
-
The obesity gene, FTO, is of ancient origin, upregulated during food deprivation and expressed in neurons of feeding-related nuclei of the brain
-
Fredriksson R, Hagglund M, Olszewski PK, Stephansson O, Jacobsson JA, Olszewska AM, Levine AS, Lindblom J, Schioth HB. The obesity gene, FTO, is of ancient origin, upregulated during food deprivation and expressed in neurons of feeding-related nuclei of the brain. Endocrinology 2008 149 : 2062 2071.
-
(2008)
Endocrinology
, vol.149
, pp. 2062-2071
-
-
Fredriksson, R.1
Hagglund, M.2
Olszewski, P.K.3
Stephansson, O.4
Jacobsson, J.A.5
Olszewska, A.M.6
Levine, A.S.7
Lindblom, J.8
Schioth, H.B.9
-
139
-
-
36749041363
-
The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase
-
Gerken T, Girard CA, Tung YC, Webby CJ, Saudek V, Hewitson KS, Yeo GS, McDonough MA, Cunliffe S, McNeill LA, Galvanovskis J, Rorsman P, Robins P, Prieur X, Coll AP, Ma M, Jovanovic Z, Farooqi IS, Sedgwick B, Barroso I, Lindahl T, Ponting CP, Ashcroft FM, O'Rahilly S, Schofield CJ. The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase. Science 2007 318 : 1469 1472.
-
(2007)
Science
, vol.318
, pp. 1469-1472
-
-
Gerken, T.1
Girard, C.A.2
Tung, Y.C.3
Webby, C.J.4
Saudek, V.5
Hewitson, K.S.6
Yeo, G.S.7
McDonough, M.A.8
Cunliffe, S.9
McNeill, L.A.10
Galvanovskis, J.11
Rorsman, P.12
Robins, P.13
Prieur, X.14
Coll, A.P.15
Ma, M.16
Jovanovic, Z.17
Farooqi, I.S.18
Sedgwick, B.19
Barroso, I.20
Lindahl, T.21
Ponting, C.P.22
Ashcroft, F.M.23
O'Rahilly, S.24
Schofield, C.J.25
more..
-
141
-
-
43049146524
-
A HapMap harvest of insights into the genetics of common disease
-
Manolio TA, Brooks LD, Collins FS. A HapMap harvest of insights into the genetics of common disease. J Clin Invest 2008 118 : 1590 1605.
-
(2008)
J Clin Invest
, vol.118
, pp. 1590-1605
-
-
Manolio, T.A.1
Brooks, L.D.2
Collins, F.S.3
-
142
-
-
38749145596
-
Shifting paradigm of association studies: Value of rare single-nucleotide polymorphisms
-
Gorlov IP, Gorlova OY, Sunyaev SR, Spitz MR, Amos CI. Shifting paradigm of association studies: value of rare single-nucleotide polymorphisms. Am J Hum Genet 2008 82 : 100 112.
-
(2008)
Am J Hum Genet
, vol.82
, pp. 100-112
-
-
Gorlov, I.P.1
Gorlova, O.Y.2
Sunyaev, S.R.3
Spitz, M.R.4
Amos, C.I.5
-
143
-
-
34347245585
-
A nonadaptive scenario explaining the genetic predisposition to obesity: The 'predation release' hypothesis
-
Speakman JR. A nonadaptive scenario explaining the genetic predisposition to obesity: the 'predation release' hypothesis. Cell Metab 2007 6 : 5 12.
-
(2007)
Cell Metab
, vol.6
, pp. 5-12
-
-
Speakman, J.R.1
-
144
-
-
34147154100
-
Medical sequencing at the extremes of human body mass
-
Ahituv N, Kavaslar N, Schackwitz W, Ustaszewska A, Martin J, Hebert S, Doelle H, Ersoy B, Kryukov G, Schmidt S, Yosef N, Ruppin E, Sharan R, Vaisse C, Sunyaev S, Dent R, Cohen J, McPherson R, Pennacchio LA. Medical sequencing at the extremes of human body mass. Am J Hum Genet 2007 80 : 779 791.
-
(2007)
Am J Hum Genet
, vol.80
, pp. 779-791
-
-
Ahituv, N.1
Kavaslar, N.2
Schackwitz, W.3
Ustaszewska, A.4
Martin, J.5
Hebert, S.6
Doelle, H.7
Ersoy, B.8
Kryukov, G.9
Schmidt, S.10
Yosef, N.11
Ruppin, E.12
Sharan, R.13
Vaisse, C.14
Sunyaev, S.15
Dent, R.16
Cohen, J.17
McPherson, R.18
Pennacchio, L.A.19
-
145
-
-
33846853084
-
The SH2B gene is associated with serum leptin and body fat in normal female twins
-
Jamshidi Y, Snieder H, Ge D, Spector TD, O'Dell SD. The SH2B gene is associated with serum leptin and body fat in normal female twins. Obesity (Silver Spring) 2007 15 : 5 9.
-
(2007)
Obesity (Silver Spring)
, vol.15
, pp. 5-9
-
-
Jamshidi, Y.1
Snieder, H.2
Ge, D.3
Spector, T.D.4
O'Dell, S.D.5
-
146
-
-
40949127393
-
How to interpret a genome-wide association study
-
Pearson TA, Manolio TA. How to interpret a genome-wide association study. JAMA 2008 299 : 1335 1344.
-
(2008)
JAMA
, vol.299
, pp. 1335-1344
-
-
Pearson, T.A.1
Manolio, T.A.2
-
147
-
-
41649092481
-
Progress in the genetics of common obesity: Size matters
-
Li S, Loos RJ. Progress in the genetics of common obesity: size matters. Curr Opin Lipidol 2008 19 : 113 121.
-
(2008)
Curr Opin Lipidol
, vol.19
, pp. 113-121
-
-
Li, S.1
Loos, R.J.2
-
148
-
-
42349112088
-
Genome-wide association studies for complex traits: Consensus, uncertainty and challenges
-
McCarthy MI, Abecasis GR, Cardon LR, Goldstein DB, Little J, Ioannidis JP, Hirschhorn JN. Genome-wide association studies for complex traits: consensus, uncertainty and challenges. Nat Rev Genet 2008 9 : 356 369.
-
(2008)
Nat Rev Genet
, vol.9
, pp. 356-369
-
-
McCarthy, M.I.1
Abecasis, G.R.2
Cardon, L.R.3
Goldstein, D.B.4
Little, J.5
Ioannidis, J.P.6
Hirschhorn, J.N.7
-
149
-
-
38449097877
-
Variants in the fat mass- and obesity-associated (FTO) gene are not associated with obesity in a Chinese Han population
-
Li H, Wu Y, Loos RJ, Hu FB, Liu Y, Wang J, Yu Z, Lin X. Variants in the fat mass- and obesity-associated (FTO) gene are not associated with obesity in a Chinese Han population. Diabetes 2008 57 : 264 268.
-
(2008)
Diabetes
, vol.57
, pp. 264-268
-
-
Li, H.1
Wu, Y.2
Loos, R.J.3
Hu, F.B.4
Liu, Y.5
Wang, J.6
Yu, Z.7
Lin, X.8
-
150
-
-
47749128415
-
Impact of nine common type 2 diabetes risk polymorphisms in Asian Indian Sikhs: PPARG2 (Pro12Ala), IGF2BP2, TCF7L2 and FTO variants confer a significant risk
-
Sanghera DK, Ortega L, Han S, Singh J, Ralhan SK, Wander GS, Mehra NK, Mulvihill JJ, Ferrell RE, Nath SK, Kamboh MI. Impact of nine common type 2 diabetes risk polymorphisms in Asian Indian Sikhs: PPARG2 (Pro12Ala), IGF2BP2, TCF7L2 and FTO variants confer a significant risk. BMC Med Genet 2008 9 : 59.
-
(2008)
BMC Med Genet
, vol.9
, pp. 59
-
-
Sanghera, D.K.1
Ortega, L.2
Han, S.3
Singh, J.4
Ralhan, S.K.5
Wander, G.S.6
Mehra, N.K.7
Mulvihill, J.J.8
Ferrell, R.E.9
Nath, S.K.10
Kamboh, M.I.11
-
151
-
-
36448953082
-
FTO polymorphisms in oceanic populations
-
Ohashi J, Naka I, Kimura R, Natsuhara K, Yamauchi T, Furusawa T, Nakazawa M, Ataka Y, Patarapotikul J, Nuchnoi P, Tokunaga K, Ishida T, Inaoka T, Matsumura Y, Ohtsuka R. FTO polymorphisms in oceanic populations. J Hum Genet 2007 52 : 1031 1035.
-
(2007)
J Hum Genet
, vol.52
, pp. 1031-1035
-
-
Ohashi, J.1
Naka, I.2
Kimura, R.3
Natsuhara, K.4
Yamauchi, T.5
Furusawa, T.6
Nakazawa, M.7
Ataka, Y.8
Patarapotikul, J.9
Nuchnoi, P.10
Tokunaga, K.11
Ishida, T.12
Inaoka, T.13
Matsumura, Y.14
Ohtsuka, R.15
-
152
-
-
34249997024
-
Replicating genotype-phenotype associations
-
Chanock SJ, Manolio T, Boehnke M, Boerwinkle E, Hunter DJ, Thomas G, Hirschhorn JN, Abecasis G, Altshuler D, Bailey-Wilson JE, Brooks LD, Cardon LR, Daly M, Donnelly P, Fraumeni JF Jr., Freimer, NB, Gerhard DS, Gunter C, Guttmacher AE, Guyer MS, Harris EL, Hoh J, Hoover R, Kong CA, Merikangas KR, Morton CC, Palmer LJ, Phimister EG, Rice JP, Roberts J, Rotimi C, Tucker MA, Vogan KJ, Wacholder S, Wijsman EM, Winn DM, Collins FS. Replicating genotype-phenotype associations. Nature 2007 447 : 655 660.
-
(2007)
Nature
, vol.447
, pp. 655-660
-
-
Chanock, S.J.1
Manolio, T.2
Boehnke, M.3
Boerwinkle, E.4
Hunter, D.J.5
Thomas, G.6
Hirschhorn, J.N.7
Abecasis, G.8
Altshuler, D.9
Bailey-Wilson, J.E.10
Brooks, L.D.11
Cardon, L.R.12
Daly, M.13
Donnelly, P.14
Fraumeni Jr., J.F.15
Freimer, N.B.16
Gerhard, D.S.17
Gunter, C.18
Guttmacher, A.E.19
Guyer, M.S.20
Harris, E.L.21
Hoh, J.22
Hoover, R.23
Kong, C.A.24
Merikangas, K.R.25
Morton, C.C.26
Palmer, L.J.27
Phimister, E.G.28
Rice, J.P.29
Roberts, J.30
Rotimi, C.31
Tucker, M.A.32
Vogan, K.J.33
Wacholder, S.34
Wijsman, E.M.35
Winn, D.M.36
Collins, F.S.37
more..
-
153
-
-
0032162184
-
National Institutes of Health
-
Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults - the evidence report. Suppl.
-
Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults - the evidence report. National Institutes of Health. Obes Res 1998 6 (Suppl. 2 51S 209S.
-
(1998)
Obes Res
, vol.6
, Issue.2
-
-
-
154
-
-
17944396193
-
Adiposity and fat distribution outcome measures: Assessment and clinical implications
-
Suppl.
-
Aronne LJ, Segal KR. Adiposity and fat distribution outcome measures: assessment and clinical implications. Obes Res 2002 10 (Suppl. 1 14S 21S.
-
(2002)
Obes Res
, vol.10
, Issue.1
-
-
Aronne, L.J.1
Segal, K.R.2
-
155
-
-
0033839458
-
Healthy percentage body fat ranges: An approach for developing guidelines based on body mass index
-
Gallagher D, Heymsfield SB, Heo M, Jebb SA, Murgatroyd PR, Sakamoto Y. Healthy percentage body fat ranges: an approach for developing guidelines based on body mass index. Am J Clin Nutr 2000 72 : 694 701.
-
(2000)
Am J Clin Nutr
, vol.72
, pp. 694-701
-
-
Gallagher, D.1
Heymsfield, S.B.2
Heo, M.3
Jebb, S.A.4
Murgatroyd, P.R.5
Sakamoto, Y.6
-
156
-
-
49549116657
-
Does obesity shorten life? the importance of well-defined interventions to answer causal questions
-
Suppl.
-
Hernan MA, Taubman SL. Does obesity shorten life? The importance of well-defined interventions to answer causal questions. Int J Obes (Lond) 2008 32 (Suppl. 3 S8 S14.
-
(2008)
Int J Obes (Lond)
, vol.32
, Issue.3
-
-
Hernan, M.A.1
Taubman, S.L.2
-
157
-
-
0034840426
-
Validity and reproducibility of ultrasonography for the measurement of intra-abdominal adipose tissue
-
Stolk RP, Wink O, Zelissen PM, Meijer R, van Gils AP, Grobbee DE. Validity and reproducibility of ultrasonography for the measurement of intra-abdominal adipose tissue. Int J Obes Relat Metab Disord 2001 25 : 1346 1351.
-
(2001)
Int J Obes Relat Metab Disord
, vol.25
, pp. 1346-1351
-
-
Stolk, R.P.1
Wink, O.2
Zelissen, P.M.3
Meijer, R.4
Van Gils, A.P.5
Grobbee, D.E.6
-
158
-
-
35548952185
-
Meta-analysis of genome-wide linkage studies in BMI and obesity
-
Saunders CL, Chiodini BD, Sham P, Lewis CM, Abkevich V, Adeyemo AA, de Andrade M, Arya R, Berenson GS, Blangero J, Boehnke M, Borecki IB, Chagnon YC, Chen W, Comuzzie AG, Deng HW, Duggirala R, Feitosa MF, Froguel P, Hanson RL, Hebebrand J, Huezo-Dias P, Kissebah AH, Li W, Luke A, Martin LJ, Nash M, Ohman M, Palmer LJ, Peltonen L, Perola M, Price RA, Redline S, Srinivasan SR, Stern MP, Stone S, Stringham H, Turner S, Wijmenga C, Collier DA. Meta-analysis of genome-wide linkage studies in BMI and obesity. Obesity (Silver Spring) 2007 15 : 2263 2275.
-
(2007)
Obesity (Silver Spring)
, vol.15
, pp. 2263-2275
-
-
Saunders, C.L.1
Chiodini, B.D.2
Sham, P.3
Lewis, C.M.4
Abkevich, V.5
Adeyemo, A.A.6
De Andrade, M.7
Arya, R.8
Berenson, G.S.9
Blangero, J.10
Boehnke, M.11
Borecki, I.B.12
Chagnon, Y.C.13
Chen, W.14
Comuzzie, A.G.15
Deng, H.W.16
Duggirala, R.17
Feitosa, M.F.18
Froguel, P.19
Hanson, R.L.20
Hebebrand, J.21
Huezo-Dias, P.22
Kissebah, A.H.23
Li, W.24
Luke, A.25
Martin, L.J.26
Nash, M.27
Ohman, M.28
Palmer, L.J.29
Peltonen, L.30
Perola, M.31
Price, R.A.32
Redline, S.33
Srinivasan, S.R.34
Stern, M.P.35
Stone, S.36
Stringham, H.37
Turner, S.38
Wijmenga, C.39
Collier, D.A.40
more..
-
159
-
-
58149293615
-
Common genetic components of obesity traits and serum leptin
-
Hasselbalch AL, Benyamin B, Visscher PM, Heitmann BL, Kyvik KO, Sorensen TI. Common genetic components of obesity traits and serum leptin. Obesity (Silver Spring) 2008 16 : 2723 2729.
-
(2008)
Obesity (Silver Spring)
, vol.16
, pp. 2723-2729
-
-
Hasselbalch, A.L.1
Benyamin, B.2
Visscher, P.M.3
Heitmann, B.L.4
Kyvik, K.O.5
Sorensen, T.I.6
-
160
-
-
54149088214
-
Epistasis - The essential role of gene interactions in the structure and evolution of genetic systems
-
Phillips PC. Epistasis - the essential role of gene interactions in the structure and evolution of genetic systems. Nat Rev Genet 2008 9 : 855 867.
-
(2008)
Nat Rev Genet
, vol.9
, pp. 855-867
-
-
Phillips, P.C.1
-
161
-
-
33847176604
-
A genome-wide association study identifies novel risk loci for type 2 diabetes
-
DOI 10.1038/nature05616, PII NATURE05616
-
Sladek R, Rocheleau G, Rung J, Dina C, Shen L, Serre D, Boutin P, Vincent D, Belisle A, Hadjadj S, Balkau B, Heude B, Charpentier G, Hudson TJ, Montpetit A, Pshezhetsky AV, Prentki M, Posner BI, Balding DJ, Meyre D, Polychronakos C, Froguel P. A genome-wide association study identifies novel risk loci for type 2 diabetes. Nature 2007 445 : 881 885. (Pubitemid 46309843)
-
(2007)
Nature
, vol.445
, Issue.7130
, pp. 881-885
-
-
Sladek, R.1
Rocheleau, G.2
Rung, J.3
Dina, C.4
Shen, L.5
Serre, D.6
Boutin, P.7
Vincent, D.8
Belisle, A.9
Hadjadj, S.10
Balkau, B.11
Heude, B.12
Charpentier, G.13
Hudson, T.J.14
Montpetit, A.15
Pshezhetsky, A.V.16
Prentki, M.17
Posner, B.I.18
Balding, D.J.19
Meyre, D.20
Polychronakos, C.21
Froguel, P.22
more..
-
162
-
-
16844366786
-
Genome-wide strategies for detecting multiple loci that influence complex diseases
-
Marchini J, Donnelly P, Cardon LR. Genome-wide strategies for detecting multiple loci that influence complex diseases. Nat Genet 2005 37 : 413 417.
-
(2005)
Nat Genet
, vol.37
, pp. 413-417
-
-
Marchini, J.1
Donnelly, P.2
Cardon, L.R.3
-
163
-
-
0038353577
-
The role of genetic polymorphisms in environmental health
-
Kelada SN, Eaton DL, Wang SS, Rothman NR, Khoury MJ. The role of genetic polymorphisms in environmental health. Environ Health Perspect 2003 111 : 1055 1064.
-
(2003)
Environ Health Perspect
, vol.111
, pp. 1055-1064
-
-
Kelada, S.N.1
Eaton, D.L.2
Wang, S.S.3
Rothman, N.R.4
Khoury, M.J.5
-
164
-
-
0345411335
-
The ubiquitous nature of epistasis in determining susceptibility to common human diseases
-
Moore JH. The ubiquitous nature of epistasis in determining susceptibility to common human diseases. Hum Hered 2003 56 : 73 82.
-
(2003)
Hum Hered
, vol.56
, pp. 73-82
-
-
Moore, J.H.1
-
165
-
-
33646234965
-
Are we ready for genome-wide association studies?
-
Thomas DC. Are we ready for genome-wide association studies? Cancer Epidemiol Biomarkers Prev 2006 15 : 595 598.
-
(2006)
Cancer Epidemiol Biomarkers Prev
, vol.15
, pp. 595-598
-
-
Thomas, D.C.1
-
166
-
-
42249101395
-
Molecular network of obesity: What does it promise for pharmacotherapy?
-
Myslobodsky M. Molecular network of obesity: what does it promise for pharmacotherapy? Obes Rev 2008 9 : 236 245.
-
(2008)
Obes Rev
, vol.9
, pp. 236-245
-
-
Myslobodsky, M.1
-
167
-
-
38849186627
-
Central and peripheral neuroendocrine peptides and signalling in appetite regulation: Considerations for obesity pharmacotherapy
-
Atkinson TJ. Central and peripheral neuroendocrine peptides and signalling in appetite regulation: considerations for obesity pharmacotherapy. Obes Rev 2008 9 : 108 120.
-
(2008)
Obes Rev
, vol.9
, pp. 108-120
-
-
Atkinson, T.J.1
-
168
-
-
39149137834
-
Single nucleotide polymorphisms of the MCHR1 gene do not affect metabolism in humans
-
Rutanen J, Pihlajamaki J, Vanttinen M, Salmenniemi U, Ruotsalainen E, Kuulasmaa T, Kainulainen S, Kuusisto J, Laakso M. Single nucleotide polymorphisms of the MCHR1 gene do not affect metabolism in humans. Obesity (Silver Spring) 2007 15 : 2902 2907.
-
(2007)
Obesity (Silver Spring)
, vol.15
, pp. 2902-2907
-
-
Rutanen, J.1
Pihlajamaki, J.2
Vanttinen, M.3
Salmenniemi, U.4
Ruotsalainen, E.5
Kuulasmaa, T.6
Kainulainen, S.7
Kuusisto, J.8
Laakso, M.9
-
169
-
-
34547651102
-
Secretory granule neuroendocrine protein 1 (SGNE1) genetic variation and glucose intolerance in severe childhood and adult obesity
-
Bouatia-Naji N, Vatin V, Lecoeur C, Heude B, Proenca C, Veslot J, Jouret B, Tichet J, Charpentier G, Marre M, Balkau B, Froguel P, Meyre D. Secretory granule neuroendocrine protein 1 (SGNE1) genetic variation and glucose intolerance in severe childhood and adult obesity. BMC Med Genet 2007 8 : 44.
-
(2007)
BMC Med Genet
, vol.8
, pp. 44
-
-
Bouatia-Naji, N.1
Vatin, V.2
Lecoeur, C.3
Heude, B.4
Proenca, C.5
Veslot, J.6
Jouret, B.7
Tichet, J.8
Charpentier, G.9
Marre, M.10
Balkau, B.11
Froguel, P.12
Meyre, D.13
|