메뉴 건너뛰기




Volumn 366, Issue 9493, 2005, Pages 1315-1323

What makes a good genetic association study?

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER DISEASE; ANALYTICAL ERROR; ARTICLE; BLADDER DISEASE; CROHN DISEASE; GENE REPLICATION; GENETIC ASSOCIATION; GENETIC DISORDER; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOME ANALYSIS; GENOTYPE; GRAVES DISEASE; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; RETINA MACULA AGE RELATED DEGENERATION; THROMBOPHILIA;

EID: 26244444318     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(05)67531-9     Document Type: Review
Times cited : (396)

References (87)
  • 1
    • 0029741063 scopus 로고    scopus 로고
    • The future of genetic studies of complex human diseases
    • N Risch, K Merikangas The future of genetic studies of complex human diseases Science 273 1996 1516 1517
    • (1996) Science , vol.273 , pp. 1516-1517
    • Risch, N.1    Merikangas, K.2
  • 2
    • 0037312921 scopus 로고    scopus 로고
    • Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease
    • KE Lohmueller, CL Pearce, M Pike, ES Lander, JN Hirschhorn Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease Nat Genet 33 2003 177 182
    • (2003) Nat Genet , vol.33 , pp. 177-182
    • Lohmueller, K.E.1    Pearce, C.L.2    Pike, M.3    Lander, E.S.4    Hirschhorn, J.N.5
  • 6
    • 0742288585 scopus 로고    scopus 로고
    • The complex interplay among factors that influence allelic association
    • KT Zondervan, LR Cardon The complex interplay among factors that influence allelic association Nat Rev Genet 5 2004 89 100
    • (2004) Nat Rev Genet , vol.5 , pp. 89-100
    • Zondervan, K.T.1    Cardon, L.R.2
  • 7
    • 0037426052 scopus 로고    scopus 로고
    • Problems of reporting genetic associations with complex outcomes
    • HM Colhoun, PM McKeigue, G Davey Smith Problems of reporting genetic associations with complex outcomes Lancet 361 2003 865 872
    • (2003) Lancet , vol.361 , pp. 865-872
    • Colhoun, H.M.1    McKeigue, P.M.2    Davey Smith, G.3
  • 8
    • 0037103172 scopus 로고    scopus 로고
    • Reporting, appraising, and integrating data on genotype prevalence and gene-disease associations
    • J Little, L Bradley, MS Bray Reporting, appraising, and integrating data on genotype prevalence and gene-disease associations Am J Epidemiol 156 2002 300 310
    • (2002) Am J Epidemiol , vol.156 , pp. 300-310
    • Little, J.1    Bradley, L.2    Bray, M.S.3
  • 9
    • 25144501575 scopus 로고    scopus 로고
    • Genetic association studies
    • HJ Cordell, DG Clayton Genetic association studies Lancet 366 2005 1121 1131
    • (2005) Lancet , vol.366 , pp. 1121-1131
    • Cordell, H.J.1    Clayton, D.G.2
  • 10
    • 0037442092 scopus 로고    scopus 로고
    • Population stratification and spurious allelic association
    • LR Cardon, LJ Palmer Population stratification and spurious allelic association Lancet 361 2003 598 604
    • (2003) Lancet , vol.361 , pp. 598-604
    • Cardon, L.R.1    Palmer, L.J.2
  • 11
    • 0034758045 scopus 로고    scopus 로고
    • Genomewide scans of complex human diseases: True linkage is hard to find
    • J Altmuller, LJ Palmer, G Fischer, H Scherb, M Wjst Genomewide scans of complex human diseases: true linkage is hard to find Am J Hum Genet 69 2001 936 950
    • (2001) Am J Hum Genet , vol.69 , pp. 936-950
    • Altmuller, J.1    Palmer, L.J.2    Fischer, G.3    Scherb, H.4    Wjst, M.5
  • 12
    • 0033624575 scopus 로고    scopus 로고
    • The common PPARg Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes
    • D Altshuler, JN Hirschhorn, M Klannemark The common PPARg Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes Nat Genet 26 2000 76 80
    • (2000) Nat Genet , vol.26 , pp. 76-80
    • Altshuler, D.1    Hirschhorn, J.N.2    Klannemark, M.3
  • 13
    • 0028314865 scopus 로고
    • Mutation in blood coagulation factor V associated with resistance to activated protein C
    • RM Bertina, BP Koeleman, T Koster Mutation in blood coagulation factor V associated with resistance to activated protein C Nature 369 1994 64 67
    • (1994) Nature , vol.369 , pp. 64-67
    • Bertina, R.M.1    Koeleman, B.P.2    Koster, T.3
  • 14
    • 0035978651 scopus 로고    scopus 로고
    • Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
    • JP Hugot, M Chamaillard, H Zouali Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease Nature 411 2001 599 603
    • (2001) Nature , vol.411 , pp. 599-603
    • Hugot, J.P.1    Chamaillard, M.2    Zouali, H.3
  • 15
    • 0027194791 scopus 로고
    • Gene dose of apolipoprotein e type 4 allele and the risk of Alzheimer's disease in late onset families
    • EH Corder, AM Saunders, WJ Strittmatter Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families Science 261 1993 921 923
    • (1993) Science , vol.261 , pp. 921-923
    • Corder, E.H.1    Saunders, A.M.2    Strittmatter, W.J.3
  • 16
    • 0032926539 scopus 로고    scopus 로고
    • Apolipoprotein e genetic variation and Alzheimer's disease. a meta-analysis
    • DC Rubinsztein, DF Easton Apolipoprotein E genetic variation and Alzheimer's disease. a meta-analysis Dement Geriatr Cogn Disord 10 1999 199 209
    • (1999) Dement Geriatr Cogn Disord , vol.10 , pp. 199-209
    • Rubinsztein, D.C.1    Easton, D.F.2
  • 17
    • 0142124733 scopus 로고    scopus 로고
    • Meta-analysis of COL1A1 Sp1 polymorphism in relation to bone mineral density and osteoporotic fracture
    • V Mann, SH Ralston Meta-analysis of COL1A1 Sp1 polymorphism in relation to bone mineral density and osteoporotic fracture Bone 32 2003 711 717
    • (2003) Bone , vol.32 , pp. 711-717
    • Mann, V.1    Ralston, S.H.2
  • 18
    • 0035060434 scopus 로고    scopus 로고
    • A COL1A1 Sp1 binding site polymorphism predisposes to osteoporotic fracture by affecting bone density and quality
    • V Mann, EE Hobson, B Li A COL1A1 Sp1 binding site polymorphism predisposes to osteoporotic fracture by affecting bone density and quality J Clin Invest 107 2001 899 907
    • (2001) J Clin Invest , vol.107 , pp. 899-907
    • Mann, V.1    Hobson, E.E.2    Li, B.3
  • 19
    • 20544471911 scopus 로고    scopus 로고
    • Strong association of the Y402H variant in complement factor H at 1q32 with susceptibility to age-related macular degeneration
    • S Zareparsi, KE Branham, M Li Strong association of the Y402H variant in complement factor H at 1q32 with susceptibility to age-related macular degeneration Am J Hum Genet 77 2005 149 153
    • (2005) Am J Hum Genet , vol.77 , pp. 149-153
    • Zareparsi, S.1    Branham, K.E.2    Li, M.3
  • 20
    • 21044453724 scopus 로고    scopus 로고
    • A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration
    • GS Hageman, DH Anderson, LV Johnson A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration Proc Natl Acad Sci USA 102 2005 7227 7232
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 7227-7232
    • Hageman, G.S.1    Anderson, D.H.2    Johnson, L.V.3
  • 21
    • 20244388812 scopus 로고    scopus 로고
    • Complement factor H variant increases the risk of age-related macular degeneration
    • JL Haines, MA Hauser, S Schmidt Complement factor H variant increases the risk of age-related macular degeneration Science 308 2005 419 421
    • (2005) Science , vol.308 , pp. 419-421
    • Haines, J.L.1    Hauser, M.A.2    Schmidt, S.3
  • 22
    • 20244380171 scopus 로고    scopus 로고
    • Complement factor H polymorphism in age-related macular degeneration
    • RJ Klein, C Zeiss, EY Chew Complement factor H polymorphism in age-related macular degeneration Science 308 2005 385 389
    • (2005) Science , vol.308 , pp. 385-389
    • Klein, R.J.1    Zeiss, C.2    Chew, E.Y.3
  • 24
    • 0037317981 scopus 로고    scopus 로고
    • Large-scale association studies of variants in genes encoding the pancreatic beta-cell KATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) confirm that the KCNJ11 E23K variant is associated with type 2 diabetes
    • AL Gloyn, MN Weedon, KR Owen Large-scale association studies of variants in genes encoding the pancreatic beta-cell KATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) confirm that the KCNJ11 E23K variant is associated with type 2 diabetes Diabetes 52 2003 568 572
    • (2003) Diabetes , vol.52 , pp. 568-572
    • Gloyn, A.L.1    Weedon, M.N.2    Owen, K.R.3
  • 25
    • 0037648405 scopus 로고    scopus 로고
    • Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease
    • H Ueda, JM Howson, L Esposito Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease Nature 423 2003 506 511
    • (2003) Nature , vol.423 , pp. 506-511
    • Ueda, H.1    Howson, J.M.2    Esposito, L.3
  • 26
    • 8544274482 scopus 로고    scopus 로고
    • Insulin-dependent diabetes mellitus (IDDM) is associated with CTLA4 polymorphisms in multiple ethnic groups
    • MP Marron, LJ Raffel, HJ Garchon Insulin-dependent diabetes mellitus (IDDM) is associated with CTLA4 polymorphisms in multiple ethnic groups Hum Mol Genet 6 1997 1275 1282
    • (1997) Hum Mol Genet , vol.6 , pp. 1275-1282
    • Marron, M.P.1    Raffel, L.J.2    Garchon, H.J.3
  • 27
    • 0042353836 scopus 로고    scopus 로고
    • CTLA-4 and its role in autoimmune thyroid disease
    • DA Chistiakov, RI Turakulov CTLA-4 and its role in autoimmune thyroid disease J Mol Endocrinol 31 2003 21 36
    • (2003) J Mol Endocrinol , vol.31 , pp. 21-36
    • Chistiakov, D.A.1    Turakulov, R.I.2
  • 28
    • 0030444451 scopus 로고    scopus 로고
    • Human type 1 diabetes and the insulin gene: Principles of mapping polygenes
    • ST Bennett, JA Todd Human type 1 diabetes and the insulin gene: principles of mapping polygenes Annu Rev Genet 30 1996 343 370
    • (1996) Annu Rev Genet , vol.30 , pp. 343-370
    • Bennett, S.T.1    Todd, J.A.2
  • 29
    • 0037100373 scopus 로고    scopus 로고
    • Pooled analysis and meta-analysis of glutathione S-transferase M1 and bladder cancer: A HuGE review
    • LS Engel, E Taioli, R Pfeiffer Pooled analysis and meta-analysis of glutathione S-transferase M1 and bladder cancer: a HuGE review Am J Epidemiol 156 2002 95 109
    • (2002) Am J Epidemiol , vol.156 , pp. 95-109
    • Engel, L.S.1    Taioli, E.2    Pfeiffer, R.3
  • 30
    • 0035812707 scopus 로고    scopus 로고
    • An apolipoprotein influencing triglycerides in humans and mice revealed by comparative sequencing
    • LA Pennacchio, M Olivier, JA Hubacek An apolipoprotein influencing triglycerides in humans and mice revealed by comparative sequencing Science 294 2001 169 173
    • (2001) Science , vol.294 , pp. 169-173
    • Pennacchio, L.A.1    Olivier, M.2    Hubacek, J.A.3
  • 31
    • 1842526874 scopus 로고    scopus 로고
    • Progress in defining the molecular basis of type 2 diabetes mellitus through susceptibility-gene identification
    • MI McCarthy Progress in defining the molecular basis of type 2 diabetes mellitus through susceptibility-gene identification Hum Mol Genet 13 suppl 1 2004 R33 R41
    • (2004) Hum Mol Genet , vol.13 , Issue.1 SUPPL.
    • McCarthy, M.I.1
  • 32
    • 0242607158 scopus 로고    scopus 로고
    • Meta-analysis and a large association study confirm a role for calpain-10 variation in type 2 diabetes susceptibility
    • MN Weedon, PE Schwarz, Y Horikawa Meta-analysis and a large association study confirm a role for calpain-10 variation in type 2 diabetes susceptibility Am J Hum Genet 73 2003 1208 1212
    • (2003) Am J Hum Genet , vol.73 , pp. 1208-1212
    • Weedon, M.N.1    Schwarz, P.E.2    Horikawa, Y.3
  • 33
    • 0346274979 scopus 로고    scopus 로고
    • New methods for finding disease-susceptibility genes: Impact and potential
    • MI McCarthy, D Smedley, W Hide New methods for finding disease-susceptibility genes: impact and potential Genome Biol 4 2003 119
    • (2003) Genome Biol , vol.4 , pp. 119
    • McCarthy, M.I.1    Smedley, D.2    Hide, W.3
  • 34
    • 0034789532 scopus 로고    scopus 로고
    • Haplotype tagging for the identification of common disease genes
    • GC Johnson, L Esposito, BJ Barratt Haplotype tagging for the identification of common disease genes Nat Genet 29 2001 233 237
    • (2001) Nat Genet , vol.29 , pp. 233-237
    • Johnson, G.C.1    Esposito, L.2    Barratt, B.J.3
  • 35
    • 0346373654 scopus 로고    scopus 로고
    • Selecting a maximally informative set of single-nucleotide polymorphisms for association analyses using linkage disequilibrium
    • CS Carlson, MA Eberle, MJ Rieder Selecting a maximally informative set of single-nucleotide polymorphisms for association analyses using linkage disequilibrium Am J Hum Genet 74 2004 106 120
    • (2004) Am J Hum Genet , vol.74 , pp. 106-120
    • Carlson, C.S.1    Eberle, M.A.2    Rieder, M.J.3
  • 36
    • 0034892062 scopus 로고    scopus 로고
    • Complex genetic diseases: Controversy over the Croesus code
    • AF Wright, ND Hastie Complex genetic diseases: controversy over the Croesus code Genome Biol 2 2001 1 8
    • (2001) Genome Biol , vol.2 , pp. 1-8
    • Wright, A.F.1    Hastie, N.D.2
  • 37
    • 0036137130 scopus 로고    scopus 로고
    • Linkage disequilibrium and the mapping of complex human traits
    • KM Weiss, AG Clark Linkage disequilibrium and the mapping of complex human traits Trends Genet 18 2002 19 24
    • (2002) Trends Genet , vol.18 , pp. 19-24
    • Weiss, K.M.1    Clark, A.G.2
  • 38
    • 0035451780 scopus 로고    scopus 로고
    • On the allelic spectrum of human disease
    • DE Reich, ES Lander On the allelic spectrum of human disease Trends Genet 17 2001 502 510
    • (2001) Trends Genet , vol.17 , pp. 502-510
    • Reich, D.E.1    Lander, E.S.2
  • 39
    • 18444369013 scopus 로고    scopus 로고
    • The structure of haplotype blocks in the human genome
    • SB Gabriel, SF Schaffner, H Nguyen The structure of haplotype blocks in the human genome Science 296 2002 2225 2229
    • (2002) Science , vol.296 , pp. 2225-2229
    • Gabriel, S.B.1    Schaffner, S.F.2    Nguyen, H.3
  • 40
    • 0036255811 scopus 로고    scopus 로고
    • Candidate-gene approaches for studying complex genetic traits: Practical considerations
    • HK Tabor, NJ Risch, RM Myers Candidate-gene approaches for studying complex genetic traits: practical considerations Nat Rev Genet 3 2002 391 397
    • (2002) Nat Rev Genet , vol.3 , pp. 391-397
    • Tabor, H.K.1    Risch, N.J.2    Myers, R.M.3
  • 41
    • 0037381021 scopus 로고    scopus 로고
    • Wanted: Regulatory SNPs
    • TJ Hudson Wanted: regulatory SNPs Nat Genet 33 2003 439 440
    • (2003) Nat Genet , vol.33 , pp. 439-440
    • Hudson, T.J.1
  • 42
    • 12144291217 scopus 로고    scopus 로고
    • Genetic variation near the hepatocyte nuclear factor-4 gene predicts susceptibility to type 2 diabetes
    • K Silander, KL Mohlke, LJ Scott Genetic variation near the hepatocyte nuclear factor-4 gene predicts susceptibility to type 2 diabetes Diabetes 53 2004 1141 1149
    • (2004) Diabetes , vol.53 , pp. 1141-1149
    • Silander, K.1    Mohlke, K.L.2    Scott, L.J.3
  • 43
    • 1842422877 scopus 로고    scopus 로고
    • A common polymorphism in the upstream promoter region of the hepatocyte nuclear factor4 gene on chromosome 20q is associated with type 2 diabetes and appears to contribute to the evidence for linkage in an Ashkenazi Jewish population
    • L Love-Gregory, J Wasson, J Ma A common polymorphism in the upstream promoter region of the hepatocyte nuclear factor4 gene on chromosome 20q is associated with type 2 diabetes and appears to contribute to the evidence for linkage in an Ashkenazi Jewish population Diabetes 53 2004 1134 1140
    • (2004) Diabetes , vol.53 , pp. 1134-1140
    • Love-Gregory, L.1    Wasson, J.2    Ma, J.3
  • 44
    • 0034777911 scopus 로고    scopus 로고
    • A distant upstream promoter of the HNF-4alpha gene connects the transcription factors involved in maturity-onset diabetes of the young
    • H Thomas, K Jaschkowitz, M Bulman A distant upstream promoter of the HNF-4alpha gene connects the transcription factors involved in maturity-onset diabetes of the young Hum Mol Genet 10 2001 2089 2097
    • (2001) Hum Mol Genet , vol.10 , pp. 2089-2097
    • Thomas, H.1    Jaschkowitz, K.2    Bulman, M.3
  • 45
    • 0035807902 scopus 로고    scopus 로고
    • A transcription factor regulatory circuit in differentiated pancreatic cells
    • SF Boj, M Parrizas, MA Maestro, J Ferrer A transcription factor regulatory circuit in differentiated pancreatic cells Proc Natl Acad Sci USA 98 2001 14481 14486
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 14481-14486
    • Boj, S.F.1    Parrizas, M.2    Maestro, M.A.3    Ferrer, J.4
  • 46
    • 0036105591 scopus 로고    scopus 로고
    • RVista for comparative sequence-based discovery of functional transcription factor binding sites
    • GG Loots, I Ovcharenko, L Pachter, I Dubchak, EM Rubin rVista for comparative sequence-based discovery of functional transcription factor binding sites Genome Res 12 2002 832 839
    • (2002) Genome Res , vol.12 , pp. 832-839
    • Loots, G.G.1    Ovcharenko, I.2    Pachter, L.3    Dubchak, I.4    Rubin, E.M.5
  • 47
    • 0037381011 scopus 로고    scopus 로고
    • In vivo characterization of regulatory polymorphisms by allele-specific quantification of RNA polymerase loading
    • JC Knight, BJ Keating, KA Rockett, DP Kwiatkowski In vivo characterization of regulatory polymorphisms by allele-specific quantification of RNA polymerase loading Nat Genet 33 2003 469 475
    • (2003) Nat Genet , vol.33 , pp. 469-475
    • Knight, J.C.1    Keating, B.J.2    Rockett, K.A.3    Kwiatkowski, D.P.4
  • 48
    • 0012789869 scopus 로고    scopus 로고
    • Allelic variation in gene expression is common in the human genome
    • HS Lo, Z Wang, Y Hu Allelic variation in gene expression is common in the human genome Genome Res 13 2003 1855 1862
    • (2003) Genome Res , vol.13 , pp. 1855-1862
    • Lo, H.S.1    Wang, Z.2    Hu, Y.3
  • 49
    • 2642583283 scopus 로고    scopus 로고
    • Mapping complex disease loci in whole-genome association studies
    • CS Carlson, MA Eberle, L Kruglyak, DA Nickerson Mapping complex disease loci in whole-genome association studies Nature 429 2004 446 452
    • (2004) Nature , vol.429 , pp. 446-452
    • Carlson, C.S.1    Eberle, M.A.2    Kruglyak, L.3    Nickerson, D.A.4
  • 50
    • 18744407845 scopus 로고    scopus 로고
    • Functional SNPs in the lymphotoxin-α gene that are associated with susceptibility to myocardial infarction
    • K Ozaki, Y Ohnishi, A Iida Functional SNPs in the lymphotoxin-α gene that are associated with susceptibility to myocardial infarction Nat Genet 32 2002 650 654
    • (2002) Nat Genet , vol.32 , pp. 650-654
    • Ozaki, K.1    Ohnishi, Y.2    Iida, A.3
  • 51
    • 0042572474 scopus 로고    scopus 로고
    • Gly972Arg variant in the insulin receptor substrate-1 gene and association with type 2 diabetes: A meta-analysis of 27 studies
    • A Jellema, MP Zeegers, EJ Feskens, PC Dagnelie, RP Mensink Gly972Arg variant in the insulin receptor substrate-1 gene and association with type 2 diabetes: a meta-analysis of 27 studies Diabetologia 46 2003 990 995
    • (2003) Diabetologia , vol.46 , pp. 990-995
    • Jellema, A.1    Zeegers, M.P.2    Feskens, E.J.3    Dagnelie, P.C.4    Mensink, R.P.5
  • 52
    • 0032897131 scopus 로고    scopus 로고
    • The relative power of family-based and case-control designs for linkage disequilibrium studies of complex human diseases. II. Individual genotyping
    • J Teng, N Risch The relative power of family-based and case-control designs for linkage disequilibrium studies of complex human diseases. II. Individual genotyping Genome Res 9 1999 234 241
    • (1999) Genome Res , vol.9 , pp. 234-241
    • Teng, J.1    Risch, N.2
  • 53
    • 0037677524 scopus 로고    scopus 로고
    • Young-onset type 2 diabetes families are the major contributors to genetic loci in the Diabetes UK Warren 2 genome scan and identify putative novel loci on chromosomes 8q21, 21q22, and 22q11
    • TM Frayling, S Wiltshire, GA Hitman Young-onset type 2 diabetes families are the major contributors to genetic loci in the Diabetes UK Warren 2 genome scan and identify putative novel loci on chromosomes 8q21, 21q22, and 22q11 Diabetes 52 2003 1857 1863
    • (2003) Diabetes , vol.52 , pp. 1857-1863
    • Frayling, T.M.1    Wiltshire, S.2    Hitman, G.A.3
  • 54
    • 1542373634 scopus 로고    scopus 로고
    • Increasing the power and efficiency of disease-marker case-control association studies through use of allele-sharing information
    • TE Fingerlin, M Boehnke, GR Abecasis Increasing the power and efficiency of disease-marker case-control association studies through use of allele-sharing information Am J Hum Genet 74 2004 432 443
    • (2004) Am J Hum Genet , vol.74 , pp. 432-443
    • Fingerlin, T.E.1    Boehnke, M.2    Abecasis, G.R.3
  • 56
    • 85059046992 scopus 로고    scopus 로고
    • Population-based family studies in genetic epidemiology
    • (in press).
    • Hopper JL, Bishop DT, Easton DF. Population-based family studies in genetic epidemiology Lancet (in press).
    • Lancet
    • Hopper, J.L.1    Bishop, D.T.2    Easton, D.F.3
  • 57
    • 0028839815 scopus 로고
    • Estimating sample sizes for binary, ordered categorical, and continuous outcomes in two group comparisons
    • MJ Campbell, SA Julious, DG Altman Estimating sample sizes for binary, ordered categorical, and continuous outcomes in two group comparisons BMJ 311 1995 1145 1148
    • (1995) BMJ , vol.311 , pp. 1145-1148
    • Campbell, M.J.1    Julious, S.A.2    Altman, D.G.3
  • 58
    • 1642295096 scopus 로고    scopus 로고
    • Assessing the probability that a positive report is false: An approach for molecular epidemiology studies
    • S Wacholder, S Chanock, M Garcia-Closas, L El Ghormli, N Rothman Assessing the probability that a positive report is false: an approach for molecular epidemiology studies J Natl Canc Inst 96 2004 434 442
    • (2004) J Natl Canc Inst , vol.96 , pp. 434-442
    • Wacholder, S.1    Chanock, S.2    Garcia-Closas, M.3    El Ghormli, L.4    Rothman, N.5
  • 59
    • 2442585696 scopus 로고    scopus 로고
    • The effects of human population structure on large genetic association studies
    • J Marchini, LR Cardon, MS Phillips, P Donnelly The effects of human population structure on large genetic association studies Nat Genet 36 2004 512 517
    • (2004) Nat Genet , vol.36 , pp. 512-517
    • Marchini, J.1    Cardon, L.R.2    Phillips, M.S.3    Donnelly, P.4
  • 60
    • 17344387757 scopus 로고    scopus 로고
    • Evaluation of single nucleotide polymorphism typing with invader on PCR amplicons and its automation
    • CA Mein, BJ Barratt, MG Dunn Evaluation of single nucleotide polymorphism typing with invader on PCR amplicons and its automation Genome Res 10 2000 330 343
    • (2000) Genome Res , vol.10 , pp. 330-343
    • Mein, C.A.1    Barratt, B.J.2    Dunn, M.G.3
  • 61
    • 0344327133 scopus 로고    scopus 로고
    • Clinical epidemiological quality in molecular genetic research: The need for methodological standards
    • ST Bogardus Jr, J Concato, AR Feinstein Clinical epidemiological quality in molecular genetic research: the need for methodological standards JAMA 281 1999 1919 1926
    • (1999) JAMA , vol.281 , pp. 1919-1926
    • Bogardus Jr., S.T.1    Concato, J.2    Feinstein, A.R.3
  • 62
    • 0942276432 scopus 로고    scopus 로고
    • What SNP genotyping errors are most costly for genetic association studies?
    • SJ Kang, D Gordon, SJ Finch What SNP genotyping errors are most costly for genetic association studies? Genet Epidemiol 26 2004 132 141
    • (2004) Genet Epidemiol , vol.26 , pp. 132-141
    • Kang, S.J.1    Gordon, D.2    Finch, S.J.3
  • 63
    • 1842859051 scopus 로고    scopus 로고
    • Power and sample size calculations for case-control genetic association tests when errors are present: Application to single nucleotide polymorphisms
    • D Gordon, SJ Finch, M Nothnagel, J Ott Power and sample size calculations for case-control genetic association tests when errors are present: application to single nucleotide polymorphisms Hum Hered 54 2002 22 33
    • (2002) Hum Hered , vol.54 , pp. 22-33
    • Gordon, D.1    Finch, S.J.2    Nothnagel, M.3    Ott, J.4
  • 64
    • 0032573850 scopus 로고    scopus 로고
    • Effect of the statistical significance of results on the time to completion and publication of randomized efficacy trials
    • JP Ioannidis Effect of the statistical significance of results on the time to completion and publication of randomized efficacy trials JAMA 279 1998 281 286
    • (1998) JAMA , vol.279 , pp. 281-286
    • Ioannidis, J.P.1
  • 65
    • 0028944305 scopus 로고
    • A note on the application of the transmission disequilibrium test when a parent is missing
    • D Curtis, PC Sham A note on the application of the transmission disequilibrium test when a parent is missing Am J Hum Genet 56 1995 811 812
    • (1995) Am J Hum Genet , vol.56 , pp. 811-812
    • Curtis, D.1    Sham, P.C.2
  • 66
    • 1542314303 scopus 로고    scopus 로고
    • Impact of genotyping errors on type I error rate of the haplotype-sharing transmission/disequilibrium test (HS-TDT)
    • M Knapp, T Becker Impact of genotyping errors on type I error rate of the haplotype-sharing transmission/disequilibrium test (HS-TDT) Am J Hum Genet 74 2004 589 591
    • (2004) Am J Hum Genet , vol.74 , pp. 589-591
    • Knapp, M.1    Becker, T.2
  • 67
    • 0037371453 scopus 로고    scopus 로고
    • Undetected genotyping errors cause apparent overtransmission of common alleles in the transmission/disequilibrium test
    • AA Mitchell, DJ Cutler, A Chakravarti Undetected genotyping errors cause apparent overtransmission of common alleles in the transmission/disequilibrium test Am J Hum Genet 72 2003 598 610
    • (2003) Am J Hum Genet , vol.72 , pp. 598-610
    • Mitchell, A.A.1    Cutler, D.J.2    Chakravarti, A.3
  • 68
    • 0036801154 scopus 로고    scopus 로고
    • The impact of genotyping error on haplotype reconstruction and frequency estimation
    • KM Kirk, LR Cardon The impact of genotyping error on haplotype reconstruction and frequency estimation Eur J Hum Genet 10 2002 616 622
    • (2002) Eur J Hum Genet , vol.10 , pp. 616-622
    • Kirk, K.M.1    Cardon, L.R.2
  • 69
    • 0036275126 scopus 로고    scopus 로고
    • BeadArray technology: Enabling an accurate, cost-effective approach to high-throughput genotyping
    • A Oliphant, DL Barker, JR Stuelpnagel, MS Chee BeadArray technology: enabling an accurate, cost-effective approach to high-throughput genotyping Biotechniques 32 suppl 2002 S56 S61
    • (2002) Biotechniques , vol.32 , Issue.SUPPL.
    • Oliphant, A.1    Barker, D.L.2    Stuelpnagel, J.R.3    Chee, M.S.4
  • 70
    • 0033838513 scopus 로고    scopus 로고
    • Identification and analysis of error types in high-throughput genotyping
    • KR Ewen, M Bahlo, SA Treloar Identification and analysis of error types in high-throughput genotyping Am J Hum Genet 67 2000 727 736
    • (2000) Am J Hum Genet , vol.67 , pp. 727-736
    • Ewen, K.R.1    Bahlo, M.2    Treloar, S.A.3
  • 71
    • 0025269067 scopus 로고
    • Inference of haplotypes from PCR-amplified samples of diploid populations
    • AG Clark Inference of haplotypes from PCR-amplified samples of diploid populations Mol Biol Evol 7 1990 111 122
    • (1990) Mol Biol Evol , vol.7 , pp. 111-122
    • Clark, A.G.1
  • 72
    • 0029130796 scopus 로고
    • Maximum-likelihood estimation of molecular haplotype frequencies in a diploid population
    • L Excoffier, M Slatkin Maximum-likelihood estimation of molecular haplotype frequencies in a diploid population Mol Biol Evol 12 1995 921 927
    • (1995) Mol Biol Evol , vol.12 , pp. 921-927
    • Excoffier, L.1    Slatkin, M.2
  • 73
    • 0242691208 scopus 로고    scopus 로고
    • A comparison of bayesian methods for haplotype reconstruction from population genotype data
    • M Stephens, P Donnelly A comparison of bayesian methods for haplotype reconstruction from population genotype data Am J Hum Genet 73 2003 1162 1169
    • (2003) Am J Hum Genet , vol.73 , pp. 1162-1169
    • Stephens, M.1    Donnelly, P.2
  • 74
    • 0036138183 scopus 로고    scopus 로고
    • Bayesian haplotype inference for multiple linked single-nucleotide polymorphisms
    • T Niu, ZS Qin, X Xu, JS Liu Bayesian haplotype inference for multiple linked single-nucleotide polymorphisms Am J Hum Genet 70 2002 157 169
    • (2002) Am J Hum Genet , vol.70 , pp. 157-169
    • Niu, T.1    Qin, Z.S.2    Xu, X.3    Liu, J.S.4
  • 75
    • 0035071957 scopus 로고    scopus 로고
    • A new statistical method for haplotype reconstruction from population data
    • M Stephens, NJ Smith, P Donnelly A new statistical method for haplotype reconstruction from population data Am J Hum Genet 68 2001 978 989
    • (2001) Am J Hum Genet , vol.68 , pp. 978-989
    • Stephens, M.1    Smith, N.J.2    Donnelly, P.3
  • 77
    • 0142059667 scopus 로고    scopus 로고
    • "are we there yet?": Deciding when one has demonstrated specific genetic causation in complex diseases and quantitative traits
    • GP Page, V George, RC Go, PZ Page, DB Allison "Are we there yet?": deciding when one has demonstrated specific genetic causation in complex diseases and quantitative traits Am J Hum Genet 73 2003 711 719
    • (2003) Am J Hum Genet , vol.73 , pp. 711-719
    • Page, G.P.1    George, V.2    Go, R.C.3    Page, P.Z.4    Allison, D.B.5
  • 78
    • 0028877463 scopus 로고
    • Genetic dissection of complex traits: Guidelines for interpreting and reporting linkage results
    • E Lander, L Kruglyak Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results Nat Genet 11 1995 241 247
    • (1995) Nat Genet , vol.11 , pp. 241-247
    • Lander, E.1    Kruglyak, L.2
  • 79
    • 0034606897 scopus 로고    scopus 로고
    • Large-scale test of hypothesised associations between the angiotensin-converting-enzyme insertion/deletion polymorphism and myocardial infarction in about 5000 cases and 6000 controls
    • B Keavney, C McKenzie, S Parish Large-scale test of hypothesised associations between the angiotensin-converting-enzyme insertion/deletion polymorphism and myocardial infarction in about 5000 cases and 6000 controls Lancet 355 2000 434 442
    • (2000) Lancet , vol.355 , pp. 434-442
    • Keavney, B.1    McKenzie, C.2    Parish, S.3
  • 80
    • 0242661936 scopus 로고    scopus 로고
    • Nonreplication in genetic association studies of obesity and diabetes research
    • DT Redden, DB Allison Nonreplication in genetic association studies of obesity and diabetes research J Nutr 133 2003 3323 3326
    • (2003) J Nutr , vol.133 , pp. 3323-3326
    • Redden, D.T.1    Allison, D.B.2
  • 81
    • 0042424602 scopus 로고    scopus 로고
    • Statistical significance for genomewide studies
    • JD Storey, R Tibshirani Statistical significance for genomewide studies Proc Natl Acad Sci USA 100 2003 9440 9445
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 9440-9445
    • Storey, J.D.1    Tibshirani, R.2
  • 82
    • 1842539516 scopus 로고    scopus 로고
    • A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other
    • DR Nyholt A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other Am J Hum Genet 74 2004 765 769
    • (2004) Am J Hum Genet , vol.74 , pp. 765-769
    • Nyholt, D.R.1
  • 83
    • 0029956803 scopus 로고    scopus 로고
    • General score tests for associations of genetic markers with disease using cases and their parents
    • DJ Schaid General score tests for associations of genetic markers with disease using cases and their parents Genet Epidemiol 13 1996 423 449
    • (1996) Genet Epidemiol , vol.13 , pp. 423-449
    • Schaid, D.J.1
  • 84
    • 0344410771 scopus 로고    scopus 로고
    • Inference on haplotype effects in case-control studies using unphased genotype data
    • MP Epstein, GA Satten Inference on haplotype effects in case-control studies using unphased genotype data Am J Hum Genet 73 2003 1316 1329
    • (2003) Am J Hum Genet , vol.73 , pp. 1316-1329
    • Epstein, M.P.1    Satten, G.A.2
  • 85
    • 1542284106 scopus 로고    scopus 로고
    • Multiple comparisons in studies of gene x gene and gene x environment interaction
    • P Kraft Multiple comparisons in studies of gene x gene and gene x environment interaction Am J Hum Genet 74 2004 582 584
    • (2004) Am J Hum Genet , vol.74 , pp. 582-584
    • Kraft, P.1
  • 86
    • 0033362236 scopus 로고    scopus 로고
    • Methods for detection of parent-of-origin effects in genetic studies of case-parents triads
    • CR Weinberg Methods for detection of parent-of-origin effects in genetic studies of case-parents triads Am J Hum Genet 65 1999 229 235
    • (1999) Am J Hum Genet , vol.65 , pp. 229-235
    • Weinberg, C.R.1
  • 87
    • 0014331116 scopus 로고
    • Statistical significance in psychological research
    • DT Lykken Statistical significance in psychological research Psychol Bull 70 1968 151 159
    • (1968) Psychol Bull , vol.70 , pp. 151-159
    • Lykken, D.T.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.