-
1
-
-
0033954892
-
Identification of two catalytic residues in RAG1 that define a single active site within the RAG1/RAG2 protein complex
-
Fugmann SD, Villey IJ. Ptaszek LM et al. Identification of two catalytic residues in RAG1 that define a single active site within the RAGl/RAG2 protein complex. Mol Cell 2000; 5:97-107. (Pubitemid 30105439)
-
(2000)
Molecular Cell
, vol.5
, Issue.1
, pp. 97-107
-
-
Fugmann, S.D.1
Villey, I.J.2
Ptaszek, L.M.3
Schatz, D.G.4
-
2
-
-
0000675571
-
Mutations of acidic residues in RAG1 define the active site of the V(D)J recombinase
-
DOI 10.1101/gad.13.23.3070
-
Kim DR, Dai Y, Mundy CL et al. Mutationsof acidic residuesin RAG1 define the active site of the V(D) J recombinase. Genes Dev 1999; 13:3070-3080. (Pubitemid 30016107)
-
(1999)
Genes and Development
, vol.13
, Issue.23
, pp. 3070-3080
-
-
Kim, D.R.1
Dai, Y.2
Mundy, C.L.3
Yang, W.4
Oettinger, M.A.5
-
3
-
-
0033380368
-
Mutational analysis of RAG1 and RAG2 identifies three catalytic amino acids in RAG1 critical for both cleavage steps of V(D)J recombination
-
DOI 10.1101/gad.13.23.3059
-
Landree MA, Wibbenmeyer JA. Roth DB. Mutational analysis of RAG1 and RAG2 identifies three catalytic amino acids in RAG1 critical for both cleavage steps of V(D)J recombination. Genes Dev 1999; 13:3059-3069. (Pubitemid 30016106)
-
(1999)
Genes and Development
, vol.13
, Issue.23
, pp. 3059-3069
-
-
Landree, M.A.1
Wibbenmeyer, J.A.2
Roth, D.B.3
-
4
-
-
0031826699
-
Distinct roles of RAG1 and RAG2 in binding the V(D)J recombination signal sequences
-
Akamatsu Y, Oettinger MA. Distinct roles of RAG1 and RAG2 in binding the V(D)J recombination signal sequences. Mol Cell Bioi 1998; 18:4670-4678. (Pubitemid 28343052)
-
(1998)
Molecular and Cellular Biology
, vol.18
, Issue.8
, pp. 4670-4678
-
-
Akamatsu, Y.1
Oettinger, M.A.2
-
5
-
-
0001265782
-
RAG1 mediates signal sequence recognition and recruitment of RAG2 in V(D)J recombination
-
DOI 10.1016/S0092-8674(00)81343-4
-
Difilippanronio MJ, McMahan CJ. Eastman QM et al. RAG1 mediates signal sequence recognition and recruitmentof RAG2 in V(D)J recombination. Cell1996; 87:253-262. (Pubitemid 26359003)
-
(1996)
Cell
, vol.87
, Issue.2
, pp. 253-262
-
-
Difilippantonio, M.J.1
McMahan, C.J.2
Eastman, Q.M.3
Spanopoulou, E.4
Schatz, D.G.5
-
6
-
-
0032126295
-
V(D)J recombination signal recognition: Distinct, overlapping DNA- protein contacts in complexes containing RAG1 with and without RAG2
-
DOI 10.1016/S1074-7613(00)80593-2
-
Swanson PC, Desiderio S. V(D)J recombination signal recognition: distinct. overlapping DNA-protein contactsin complexes containing RAG1 with and without RAG2. Immunity 1998; 9:115-125. (Pubitemid 28361300)
-
(1998)
Immunity
, vol.9
, Issue.1
, pp. 115-125
-
-
Swanson, P.C.1
Desiderio, S.2
-
7
-
-
0032939926
-
Detection of RAG protein-V(D)J recombination signal interactions near the site of DNA cleavage by UV cross-linking
-
Eastman QM, Villey IJ. Schatz DG. Detection of RAGprotein-V(D)J recombination signal interactions near the site of DNA cleavage by UV cross-linking. Mol CelI Bioi 1999; 19: 3788-3797. (Pubitemid 29193838)
-
(1999)
Molecular and Cellular Biology
, vol.19
, Issue.5
, pp. 3788-3797
-
-
Eastman, Q.M.1
Villey, I.J.2
Schatz, D.G.3
-
8
-
-
0032908830
-
RAG-2 promotes heptamer occupancy by RAG-1 in the assembly of a V(D)J initiation complex
-
Swanson PC, Desiderio S. RAG-2promoteshepramer occupancy by RAG-l in the assembly of a V(D)J initiation complex. Mol Cell Bioi 1999; 19:3674-3683. (Pubitemid 29193827)
-
(1999)
Molecular and Cellular Biology
, vol.19
, Issue.5
, pp. 3674-3683
-
-
Swanson, P.C.1
Desiderio, S.2
-
9
-
-
0030964130
-
A stable RAG1-RAG2-DNA complex that is active in V(D)J cleavage
-
Hiom K, GellertM. A stable RAGl-RAG2-DNA complex that is active in V(D)J cleavage. Cell 1997; 88:65-72. (Pubitemid 27181471)
-
(1997)
Cell
, vol.88
, Issue.1
, pp. 65-72
-
-
Hiom, K.1
Gellert, M.2
-
10
-
-
0035108439
-
Separation-of-function mutants reveal critical roles for RAG2 in both the cleavage and joining steps of V(D)J recombination
-
DOI 10.1016/S1097-2765(01)00156-3
-
Qiu JX, Kale SB. Yarnell Schultz H et al. Separation-of-function mutantsreveal critical roles for RAG2 in both the cleavage and joining steps of V(D)J recombination. Mol Cell 2001; 7:77-87. (Pubitemid 32162901)
-
(2001)
Molecular Cell
, vol.7
, Issue.1
, pp. 77-87
-
-
Qiu, J.-X.1
Kale, S.B.2
Schultz, H.Y.3
Roth, D.B.4
-
11
-
-
0028307661
-
Analysis of regions of RAG-2 important for V(D)J recombination
-
Cuomo CA, Oettinger MA. Analysis of regions of RAG-2important for V(D)J recombination. Nucleic Acids Res 1994; 22:1810-1814. (Pubitemid 24169880)
-
(1994)
Nucleic Acids Research
, vol.22
, Issue.10
, pp. 1810-1814
-
-
Cuomo, C.A.1
Oettinger, M.A.2
-
12
-
-
0032541328
-
Dual role of RAG2 in V(D)J recombination: Catalysis and regulation of ordered Ig gene assembly
-
DOI 10.1093/emboj/17.16.4881
-
Kirch SA, Rathbun GA. Oettinger MA.Dual role of RAG2 in V(D)J recombination: catalysis and regulation of ordered Ig geneassembly. EMBO J 1998; 17:4881-4886. (Pubitemid 28377188)
-
(1998)
EMBO Journal
, vol.17
, Issue.16
, pp. 4881-4886
-
-
Kirch, S.A.1
Rathbun, G.A.2
Oettinger, M.A.3
-
14
-
-
0028237683
-
Definition of a core region of RAG-2 that is functional in V(D)J recombination
-
Sadofsky MJ, Hesse JE. Gellert M. Definition of a core region of RAG-2 that is functional in V(D)J recombination. Nucleic Acids Res 1994; 22:1805-1809. (Pubitemid 24169879)
-
(1994)
Nucleic Acids Research
, vol.22
, Issue.10
, pp. 1805-1809
-
-
Sadofsky, M.J.1
Hesse, J.E.2
Gellert, M.3
-
17
-
-
0035697242
-
Increased accumulation of hybrid V(D)J joins in cells expressing truncated versus full-length RAGs
-
DOI 10.1016/S1097-2765(01)00423-3
-
Sekiguchi JA, Whitlow S. Alt FW Increased accumulation of hybrid V(D)J joins in cells expressing truncated versus full-length RAGs. Mol Ce1I 2001; 8:1383-1390. (Pubitemid 34085007)
-
(2001)
Molecular Cell
, vol.8
, Issue.6
, pp. 1383-1390
-
-
Sekiguchi, J.1
Whitlow, S.2
Alt, F.W.3
-
18
-
-
0037417795
-
Deletion of the RAG2 C terminus leads to impaired lymphoid development in mice
-
DOI 10.1073/pnas.0237043100
-
Akamatsu Y, Monroe R. Dudley DD et al.Deletionof the RAG2C terminus leads to impaired lymphoid development in mice. Proc Natl Acad Sci USA 2003; 100:1209-1214. (Pubitemid 36183981)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.3
, pp. 1209-1214
-
-
Akamatsu, Y.1
Monroe, R.2
Dudley, D.D.3
Elkin, S.K.4
Gartner, F.5
Talukder, S.R.6
Takahama, Y.7
Alt, F.W.8
Bassing, C.H.9
Oettinger, M.A.10
-
19
-
-
0036850786
-
The "dispensable" portion of RAG2 is necessary for efficient V-to-DJ rearrangement during B and T cell development
-
DOI 10.1016/S1074-7613(02)00448-X
-
Liang HE, Hsu LY, Cado D ct aI.The "dispensable" portion of RAG2is necessary for efficient V-to-DJ rearrangement duringB- and T-celldevelopment. Immunity 2002; 17:639-651. (Pubitemid 35351509)
-
(2002)
Immunity
, vol.17
, Issue.5
, pp. 639-651
-
-
Liang, H.-E.1
Hsu, L.-Y.2
Cado, D.3
Cowell, L.G.4
Kelsoe, G.5
Schlissel, M.S.6
-
20
-
-
4344571097
-
Increased frequency of aberrant V(D)J recombination products in core RAG-expressing mice
-
DOI 10.1093/nar/gkh778
-
Talukder SR, Dudley DD. Alt FWet al. Increased frequency of aberrant V(D)J recombination products in core RAG-expressing mice. Nucleic Acids Res 2004; 32:4539-4549. (Pubitemid 39317732)
-
(2004)
Nucleic Acids Research
, vol.32
, Issue.15
, pp. 4539-4549
-
-
Talukder, S.R.1
Dudley, D.D.2
Alt, F.W.3
Takahama, Y.4
Akamatsu, Y.5
-
21
-
-
0030498092
-
A conserved degradation signal regulates RAG-2 accumulation during cell division and links V(D)J recombination to the cell cycle
-
DOI 10.1016/S1074-7613(00)80272-1
-
Li Z, Dordai DI. LeeJ et al.A conserved degradation signal regulates RAG-2 accumulation during celI division and links V(D)J recombination to the cellcycle. Immunity 1996; 5:575-589. (Pubitemid 27062067)
-
(1996)
Immunity
, vol.5
, Issue.6
, pp. 575-589
-
-
Li, Z.1
Dordai, D.I.2
Lee, J.3
Desiderio, S.4
-
22
-
-
0027296517
-
Regulation of V(D)J recombination activator protein RAG-2 by phosphorylation
-
LinWC. Desiderio S. Regulation of V(D)J recombination activator protein RAG-2by phosphorylation. Science 1993;260:953-959. (Pubitemid 23209964)
-
(1993)
Science
, vol.260
, Issue.5110
, pp. 953-959
-
-
Lin, W.-C.1
Desiderio, S.2
-
25
-
-
0027769386
-
Double-strand signal sequence breaks in V(D)J recombination are blunt, 5'- phosphorylated, RAG-dependent, and cell cycle regulated
-
Schlissel M, Constantinescu A. Morrow T et al. Double-strand signal sequence breaks in V(D)J recombination are blunt. S'-phosphorylared, RAG-dependent and cell cycle regulated. Genes Dev 1993; 7:2520-2532. (Pubitemid 24021009)
-
(1993)
Genes and Development
, vol.7
, Issue.12 B
, pp. 2520-2532
-
-
Schlissel, M.1
Constantinescu, A.2
Morrow, T.3
Baxter, M.4
Peng, A.5
-
26
-
-
1542289024
-
Cycle-dependent Accumulation in Vivo of Transposition-competent Complexes between Recombination Signal Ends and Full-length RAG Proiteins
-
DOI 10.1074/jbc.M311219200
-
Jiang H, Ross AE. Desiderio S. Cell cycle-dependent accumulation in vivo of transposition-competent complexes between recombination signal ends and full-length RAG proteins. J Biol Chern 2004; 279:8478-8486. (Pubitemid 38294741)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.9
, pp. 8478-8486
-
-
Jiang, H.1
Ross, A.E.2
Desiderio, S.3
-
27
-
-
0042091962
-
Overlapping signals for protein degradation and nuclear localization define a role for intrinsic RAG-2 nuclear uptake in dividing cells
-
DOI 10.1128/MCB.23.15.5308-5319.2003
-
Ross AE,Vuica M. Desiderio S. Overlapping signals for proteindegradation and nuclear localization define a role for intrinsic RAG-2 nuclear uptakein dividing cells. Mol Cell Biol 2003; 23:5308-5319. (Pubitemid 36950886)
-
(2003)
Molecular and Cellular Biology
, vol.23
, Issue.15
, pp. 5308-5319
-
-
Ross, A.E.1
Vuica, M.2
Desiderio, S.3
-
28
-
-
20444403003
-
Ubiquitylation of RAG-2 by Skp2-SCF links destruction of the V(D)J recombinase to the cell cycle
-
DOI 10.1016/j.molcel.2005.05.011, PII S1097276505013171
-
Jiang H. Chang FC. Ross AE et al. Ubiquitylation of RAG-2 by Skp2-SCF linksdestruction of the V(D) J recombinase to the cellcycle. Mol Cell 2005; 18:699-709. (Pubitemid 40804805)
-
(2005)
Molecular Cell
, vol.18
, Issue.6
, pp. 699-709
-
-
Jiang, H.1
Chang, F.-C.2
Ross, A.E.3
Lee, J.4
Nakayama, K.5
Nakayama, K.6
Desiderio, S.7
-
29
-
-
0032530658
-
Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells
-
DOI 10.1093/emboj/17.18.5497
-
Takata M, Sasaki MS, Sonoda E et al. Homologous recombination and nonhomologous end-joining pathways of DNA double-strandbreakrepair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells. EMBO J 1998; 17:5497-5508. (Pubitemid 28427063)
-
(1998)
EMBO Journal
, vol.17
, Issue.18
, pp. 5497-5508
-
-
Takata, M.1
Sasaki, M.S.2
Sonoda, E.3
Morrison, C.4
Hashimoto, M.5
Utsumi, H.6
Yamaguchi-Iwai, Y.7
Shinohara, A.8
Takeda, S.9
-
30
-
-
0033843853
-
Factors that influence formation of B-cell repertoire
-
Feeney AJ,Factors that influence formation of B-cell repertoire. Immunol Res2000; 21:195-202.
-
(2000)
Immunol Res
, vol.21
, pp. 195-202
-
-
Feeney, A.J.1
-
31
-
-
0041852607
-
Effect of CpG methylation on RAG1/RAG2 reactivity: Implications of direct and indirect mechanisms for controlling V (D) J cleavage
-
DOI 10.1038/sj.embor.embor904
-
Nakase H, Takahama Y,Akamatsu Y. Effect of CpG methylation on RAG1/RAG2 reactiviry: implications of direct and indirectmechanisms for controlling V(D)J cleavage. EMBO Rep 2003;4:774-780. (Pubitemid 37063185)
-
(2003)
EMBO Reports
, vol.4
, Issue.8
, pp. 774-780
-
-
Nakase, H.1
Takahama, Y.2
Akamatsu, Y.3
-
32
-
-
0033103012
-
Control of V(D)J recombinational accessibility of the Dδ1 gene segment at the TCRδ locus by a germline promoter
-
WhitehurstCE, Chattopadhyay 5, ChenJ. Control of V(D)J recombinational accessibiliry of the D beta 1 genesegment at the TCR beta locus by a germline promoter. Immunity 1999;10:313-322. (Pubitemid 29165286)
-
(1999)
Immunity
, vol.10
, Issue.3
, pp. 313-322
-
-
Whitehurst, C.E.1
Chattopadhyay, S.2
Chen, J.3
-
33
-
-
0034605064
-
Chromatin remodeling by the T-cell receptor (TCR)-beta gene enhancer dotingearly T-celldevelopment: Implications for the control of TCR-betalocus recombination
-
Mathieu N, HempelWM, Spicuglia 5 et al.Chromatin remodeling by the T-cell receptor (TCR)-beta gene enhancer dotingearly T-celldevelopment: Implications for the control of TCR-betalocus recombination. J Exp Med 2000; 192:625-636.
-
(2000)
J Exp Med
, vol.192
, pp. 625-636
-
-
Mathieu, N.1
Hempel, W.M.2
Spicuglia, S.3
-
34
-
-
0033635229
-
Deletion of gennline promoterPD beta 1 fromthe TCR betalocus causes hypermethylation that impairs D beta 1 recombination by multiple mechanisms
-
Whitehurst CE, Schlissel MS,Chen J. Deletion of gennline promoter PD beta 1 fromthe TCR betalocus causes hypermethylation that impairs D beta 1 recombination by multiple mechanisms. Immuniry 2000; 13:703-714.
-
(2000)
Immuniry
, vol.13
, pp. 703-714
-
-
Whitehurst, C.E.1
Schlissel, M.S.2
Chen, J.3
-
35
-
-
0032526136
-
κ chain monoallelic demethylation and the establishment of allelic exclusion
-
Mostoslavsky R, Singh N, Kirillov A et al. Kappa chain monoallelic demethylation and the establishment of allelic exclusion. Genes Dev 1998;12:1801-1811. (Pubitemid 28304333)
-
(1998)
Genes and Development
, vol.12
, Issue.12
, pp. 1801-1811
-
-
Mostoslavsky, R.1
Singh, N.2
Kirillov, A.3
Pelanda, R.4
Cedar, H.5
Chess, A.6
Bergman, Y.7
-
36
-
-
13944262010
-
Epigenetic ontogeny of the Igk locus during B cell development
-
DOI 10.1038/ni1154
-
GoldmitM, Ji Y, Skok J et al Epigenetic ontogeny of the Igklocus doting B-cell development. Nat Immunol 2005; 6:198-203. (Pubitemid 40268201)
-
(2005)
Nature Immunology
, vol.6
, Issue.2
, pp. 198-203
-
-
Goldmit, M.1
Ji, Y.2
Skok, J.3
Roldan, E.4
Jung, S.5
Cedar, H.6
Bergmann, Y.7
-
37
-
-
0029894165
-
Cell type-specific chromatin structure determines the targeting of V(D)J recombinase activity in vitro
-
DOI 10.1016/S0092-8674(00)81272-6
-
Stanhope-Baker P, Hudson KM, Shaffet Al et al. Cell type-specific chromatin structuredetermines the targeting of V(D)J recombinase activity in vitro. Cell 1996; 85:887-897. (Pubitemid 26192139)
-
(1996)
Cell
, vol.85
, Issue.6
, pp. 887-897
-
-
Stanhope-Baker, P.1
Hudson, K.M.2
Shaffer, A.L.3
Constantinescu, A.4
Schlissel, M.S.5
-
38
-
-
0032239155
-
Accessibility of nucleosomal DNA to V(D)J cleavage is modulated by RSS positioning and HMG1
-
Kwon J, Imbalzano AN, Matthews Aet al. Accessibiliry of nucleosomal DNAto V(D)Jcleavage is modulated by RSS positioning and HMG1. Mol Cell 1998; 2:829-839. (Pubitemid 128378990)
-
(1998)
Molecular Cell
, vol.2
, Issue.6
, pp. 829-839
-
-
Kwon, J.1
Imbalzano, A.N.2
Matthews, A.3
Oettinger, M.A.4
-
39
-
-
0033168204
-
Nucleosome structure completely inhibits in vitro cleavage by the V(D)J recombinase
-
DOI 10.1093/emboj/18.13.3712
-
GoldingA, Chandler S, Ballestar E et al. Nucleosome structurecompletely inhibits in vitro cleavage by the V(D)J recombinase. EMBO J 1999;18:3712-3723. (Pubitemid 29308850)
-
(1999)
EMBO Journal
, vol.18
, Issue.13
, pp. 3712-3723
-
-
Golding, A.1
Chandler, S.2
Ballestar, E.3
Wolffe, A.P.4
Schlissel, M.S.5
-
40
-
-
0033638506
-
Histone acerylation and hSWI/SNF remodeling act in concert to stimulate V(D)J cleavage of nucleosomal
-
Kwon J, Morshead KB, Guyon JR et al. Histone acerylation and hSWI/SNF remodeling act in concert to stimulate V(D)J cleavage of nucleosomal DNA. Mol Cell 2000;6:1037-1048.
-
(2000)
DNA. Mol Cell
, vol.6
, pp. 1037-1048
-
-
Kwon, J.1
Morshead, K.B.2
Guyon, J.R.3
-
41
-
-
0141753136
-
Regulation of V(D)J recombination by nucleosome positioning at recombination signal sequences
-
DOI 10.1093/emboj/cdg487
-
Baumann M, Mamais A, McBlane F et aL Regulation of V(D)J recombination by nucleosome positioning at recombination signal sequences. EMBO J 2003;22:5197-5207. (Pubitemid 37222039)
-
(2003)
EMBO Journal
, vol.22
, Issue.19
, pp. 5197-5207
-
-
Baumann, M.1
Mamais, A.2
McBlane, F.3
Xiao, H.4
Boyes, J.5
-
42
-
-
0035890244
-
Stepwise activation of the immunoglobulin μ heavy chain gene locus
-
DOI 10.1093/emboj/20.22.6394
-
Chowdhury D, Sen R. Stepwise activation of the immunoglobulin mu heavy chaingenelocus. EMBO J 2001; 20:6394-6403. (Pubitemid 33078712)
-
(2001)
EMBO Journal
, vol.20
, Issue.22
, pp. 6394-6403
-
-
Chowdhury, D.1
Sen, R.2
-
43
-
-
0037332014
-
Transient IL-7/IL-7R signaling provides a mechanism for feedback inhibition of immunoglobulin heavy chain gene rearrangements
-
DOI 10.1016/S1074-7613(03)00030-X
-
Chowdhury D, Sen R. Transient IL-7/IL-7Rsignaling provides a mechanism for feedback inhibition of immunoglobulin heavy chaingenerearrangements. Immunity 2003; 18:229-241. (Pubitemid 36262998)
-
(2003)
Immunity
, vol.18
, Issue.2
, pp. 229-241
-
-
Chowdhury, D.1
Sen, R.2
-
44
-
-
0141785171
-
Transcription factors controlling the beginning and end of B-cell differentiation
-
DOI 10.1016/j.gde.2003.08.004
-
Johnson K, Calame K. Transcription factors controlling the beginning and end of B-cell differentiation. Curt Opin Genet Dev 2003; 13:522-528. (Pubitemid 37204930)
-
(2003)
Current Opinion in Genetics and Development
, vol.13
, Issue.5
, pp. 522-528
-
-
Johnson, K.1
Calame, K.2
-
45
-
-
0034695501
-
A role for histone acetylation in the developmental regulation of VOJ recombination
-
McMurry MT, Krangel MS. A role for histone acetylation in the developmental regulation of VOJ recombination. Science 2000; 287:495-498.
-
(2000)
Science
, vol.287
, pp. 495-498
-
-
McMurry, M.T.1
Krangel, M.S.2
-
46
-
-
0036489183
-
A change in the structure of Vδ chromatin associated with TCR δ allelic exclusion
-
Tripathi R, Jackson A, Krangel MS. A change in the structureof Vberachromatin associated with TCR beta allelic exclusion. J Immunol 2002; 168:2316-2324. (Pubitemid 34171833)
-
(2002)
Journal of Immunology
, vol.168
, Issue.5
, pp. 2316-2324
-
-
Tripathi, R.1
Jackson, A.2
Krangel, M.S.3
-
47
-
-
4444267069
-
H locus depends on Pax5
-
DOI 10.1038/ni1099
-
JohnsonK, Pflgh DL, Yu D et al B-cell-spccific loss of histone3 lysine 9 methylation in the V(H) locus depends on Pax5. Nat Immunol 2004;5:853-861. (Pubitemid 39172979)
-
(2004)
Nature Immunology
, vol.5
, Issue.8
, pp. 853-861
-
-
Johnson, K.1
Pflugh, D.L.2
Yu, D.3
Hesslein, D.G.T.4
Lin, K.-I.5
Bothwell, A.L.M.6
Thomas-Tikhonenko, A.7
Schatz, D.G.8
Calame, K.9
-
48
-
-
0141705373
-
Antigen receptor loci poised for V(D)J rearrangement are broadly associated with BRG1 and flanked by peaks of histone H3 dimethylated at lysine 4
-
DOI 10.1073/pnas.1932643100
-
Morshead KB, Ciccone DN, Taverna SD et al. Antigen receptor locipoisedfor V(D)J rearrangement are broadly associated with BRG1 and flanked by peaks of histoneH3 dimethylated at lysine 4. Proc Nad Acad Sci USA 2003; 100:11577-11582. (Pubitemid 37205978)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.20
, pp. 11577-11582
-
-
Morshead, K.B.1
Ciccone, D.N.2
Taverna, S.D.3
Allis, C.D.4
Oettinger, M.A.5
-
49
-
-
1542377316
-
Targeted inhibition of V(D)J recombination by a histone methyltransferase
-
DOI 10.1038/ni1042
-
Osipovich O, Milley R, Meade A et al. Targeted inhibitionof V(D)J recombination by a histone rnethyltransferase. Nat Immunol 2004; 5:309-316. (Pubitemid 38332128)
-
(2004)
Nature Immunology
, vol.5
, Issue.3
, pp. 309-316
-
-
Osipovich, O.1
Milley, R.2
Meade, A.3
Tachibana, M.4
Shinkai, Y.5
Krangel, M.S.6
Oltz, E.M.7
-
50
-
-
47949091985
-
Functional analysis of histonemethyltransferase g9ain B- and T-Iymphocytes
-
Thomas LR,Miyashita H, Cobb RM et al. Functional analysis of histonemethyltransferase g9ain B- and T-Iymphocytes. J Immunol 2008; 181:485-493.
-
(2008)
J Immunol
, vol.181
, pp. 485-493
-
-
Thomas, L.R.1
Miyashita, H.2
Cobb, R.M.3
-
51
-
-
33751116960
-
3rd Reinberg D Histone H3 Lys 4 methylation: Caught in a bind?
-
Sims RJ 3rd, Reinberg D. Histone H3 Lys 4 methylation: caught in a bind? Genes Dev 2006; 20:2779-2786.
-
(2006)
Genes Dev
, vol.20
, pp. 2779-2786
-
-
Sims, R.J.1
-
52
-
-
3042750473
-
Histone 3 lysine 4 methylation during the pre-B to immature B-cell transition
-
DOI 10.1093/nar/gkh523
-
Perkins EJ, Kee BL, Ramsden DA. Histone 3 lysine 4 methylation doting the pre-B to immature B-cell transition. Nucleic Acids Res 2004;32:1942-1947. (Pubitemid 38849352)
-
(2004)
Nucleic Acids Research
, vol.32
, Issue.6
, pp. 1942-1947
-
-
Perkins, E.J.1
Kee, B.L.2
Ramsden, D.A.3
-
53
-
-
34548247115
-
H-Cμ Domain of the Immunoglobulin Heavy-Chain Gene Locus
-
DOI 10.1016/j.molcel.2007.07.010, PII S1097276507004819
-
Chakraborry T, Chowdhury D, Keyes A et al. Repeat organization and epigenetic regulation of the DH-Cmu domain of the immunoglobulin heavy-chaingenelocus. Mol Cell 2007; 27:842-850. (Pubitemid 47333226)
-
(2007)
Molecular Cell
, vol.27
, Issue.5
, pp. 842-850
-
-
Chakraborty, T.1
Chowdhury, D.2
Keyes, A.3
Jani, A.4
Subrahmanyam, R.5
Ivanova, I.6
Sen, R.7
-
54
-
-
35349024178
-
A Plant Homeodomain in Rag-2 that Binds Hypermethylated Lysine 4 of Histone H3 Is Necessary for Efficient Antigen-Receptor-Gene Rearrangement
-
DOI 10.1016/j.immuni.2007.09.005, PII S1074761307004487
-
Liu Y, Subrahmanyam R, Chakraborry T et al. A plant homeodomain in RAG-2 that binds Hypermethylated lysine 4 of histoneH3 is necessary for efficient antigen-receptor-gene rearrangement. Immunity 2007;27:561-571. (Pubitemid 47615506)
-
(2007)
Immunity
, vol.27
, Issue.4
, pp. 561-571
-
-
Liu, Y.1
Subrahmanyam, R.2
Chakraborty, T.3
Sen, R.4
Desiderio, S.5
-
55
-
-
37249041657
-
RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination
-
DOI 10.1038/nature06431, PII NATURE06431
-
Matthews AG, Kuo AJ, Ramon-Maiques S et al. RAG2PHD lingercouples histoneH3 lysine 4 trimethylation with V(D)J recombination. Nature 2007;450:1106-1110. (Pubitemid 350273622)
-
(2007)
Nature
, vol.450
, Issue.7172
, pp. 1106-1110
-
-
Matthews, A.G.W.1
Kuo, A.J.2
Ramon-Maiques, S.3
Han, S.4
Champagne, K.S.5
Ivanov, D.6
Gallardo, M.7
Carney, D.8
Cheung, P.9
Ciccone, D.N.10
Walter, K.L.11
Utz, P.J.12
Shi, Y.13
Kutateladze, T.G.14
Yang, W.15
Gozani, O.16
Oettinger, M.A.17
-
56
-
-
0037047323
-
Methylation of histone H3 by COMPASS requires ubiquitination of histone H2B by Rad6
-
DOI 10.1074/jbc.C200348200
-
Dover J, Schneider J, Tawiah-Boateng MA et al. Methylation of histone H3 by COMPASS requires ubiquitination of histoneH2B by Rad6. J Biol Chern 2002; 277:28368-28371. (Pubitemid 41079257)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.32
, pp. 28368-28371
-
-
Dover, J.1
Schneider, J.2
Tawiah-Boateng, M.A.3
Wood, A.4
Dean, K.5
Johnston, M.6
Shilatifard, A.7
-
57
-
-
0037019333
-
Ubiquitination of histone H2B regulates H3 methylation and gene silencing in yeast
-
DOI 10.1038/nature00883
-
Sun ZW, Allis CD. Ubiquitination of histone H2B regulates H3 methylation and gene silencing in yeast. Nature 2002; 418:104-108. (Pubitemid 34742580)
-
(2002)
Nature
, vol.418
, Issue.6893
, pp. 104-108
-
-
Sun, Z.-W.1
Allis, C.D.2
-
58
-
-
36849046285
-
Histone Crosstalk between H2B Monoubiquitination and H3 Methylation Mediated by COMPASS
-
DOI 10.1016/j.cell.2007.09.046, PII S0092867407013505
-
Lee IS, Shukla A. Schneider J et al. Histone crosstalk between H2B monoubiquitination and H3 methylation mediated by COMPASS. Cell 2007; 131:1084-1096. (Pubitemid 350235018)
-
(2007)
Cell
, vol.131
, Issue.6
, pp. 1084-1096
-
-
Lee, J.-S.1
Shukla, A.2
Schneider, J.3
Swanson, S.K.4
Washburn, M.P.5
Florens, L.6
Bhaumik, S.R.7
Shilatifard, A.8
-
59
-
-
0242361623
-
Transcriptional activation via sequential histone H2B ubiquitylation and deubiquitylation, mediated by SAGA-associated Ubp8
-
DOI 10.1101/gad.1144003
-
Henry KW; Wyce A. Lo WS et al. Transcriptional activation via sequential histone H2B ubiquitylation and deubiquirylanon, mediated by SAGA-associated Ubp8. Genes Dev 2003; 17:2648-2663. (Pubitemid 37363070)
-
(2003)
Genes and Development
, vol.17
, Issue.21
, pp. 2648-2663
-
-
Henry, K.W.1
Wyce, A.2
Lo, W.-S.3
Duggan, L.J.4
Emre, N.C.T.5
Kao, C.-F.6
Pillus, L.7
Shilatifard, A.8
Osley, M.A.9
Berger, S.L.10
-
60
-
-
0344442779
-
Transcriptional regulation by histone ubiquitination and deubiquitination
-
DOI 10.1101/gad.1156403
-
Zhang Y, Transcriptional regulation by histone ubiquitination and deubiquitinarion . Genes Dev 2003; 17:2733-2740. (Pubitemid 37463282)
-
(2003)
Genes and Development
, vol.17
, Issue.22
, pp. 2733-2740
-
-
Zhang, Y.1
-
61
-
-
0942290540
-
Rad6 plays a role in transcriptional activation through ubiquitylation of histone H2B
-
DOI 10.1101/gad.1149604
-
Kao CF, Hillyer C. Tsukuda T et al. Rad6 plays a role in transcriptional activation through ubiquitylation of histone H2B. Genes Dev 2004; 18:184-195. (Pubitemid 38141786)
-
(2004)
Genes and Development
, vol.18
, Issue.2
, pp. 184-195
-
-
Kao, C.-F.1
Hillyer, C.2
Tsukuda, T.3
Henry, K.4
Berger, S.5
Osley, M.A.6
-
62
-
-
11844297340
-
Histone H2B ubiquitylation is associated with elongating RNA polymerase II
-
DOI 10.1128/MCB.25.2.637-651.2005
-
Xiao T, Kao CF, Krogan NJ et al Histone H2B ubiquitylation is associated with elongating RNA polymerase 11. Mol Cell Biol 2005; 25:637-651. (Pubitemid 40096585)
-
(2005)
Molecular and Cellular Biology
, vol.25
, Issue.2
, pp. 637-651
-
-
Xiao, T.1
Kao, C.-F.2
Krogan, N.J.3
Sun, Z.-W.4
Greenblatt, J.F.5
Osley, M.A.6
Strahl, B.D.7
-
63
-
-
43149122898
-
Monoubiquitinated H2B is associated with the transcribed region of highly expressedgenes in human cells
-
Minsky N, Shema E. Field Y et al. Monoubiquitinated H2B is associated with the transcribed region of highly expressedgenes in human cells. Nat Cell Biol 2008; 10:483-488.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 483-488
-
-
Minsky, N.1
Shema, E.2
Field, Y.3
-
64
-
-
35348986412
-
Arginine methylation at histone H3R2 controls deposition of H3K4 trimethylation
-
DOI 10.1038/nature06160, PII NATURE06160
-
Kirmizis A, Santos-Rosa H. Penkert CJ et al. Arginine methylation at histone H3R2 controls deposition ofH3K4 rrimethylation. Nature 2007; 449:928-932. (Pubitemid 47598603)
-
(2007)
Nature
, vol.449
, Issue.7164
, pp. 928-932
-
-
Kirmizis, A.1
Santos-Rosa, H.2
Penkett, C.J.3
Singer, M.A.4
Vermeulen, M.5
Mann, M.6
Bahler, J.7
Green, R.D.8
Kouzarides, T.9
-
65
-
-
29244460109
-
Double chromodomains cooperate to recognize the methylated histone H3 tail
-
DOI 10.1038/nature04290
-
Flanagan JF, Mi LZ. Chruszcz M et al. Double chromodomains cooperate to recognize the methylated histone H3 tail. Nature 2005; 438:1181-1185. (Pubitemid 41831690)
-
(2005)
Nature
, vol.438
, Issue.7071
, pp. 1181-1185
-
-
Flanagan, J.F.1
Mi, L.-Z.2
Chruszcz, M.3
Cymborowski, M.4
Clines, K.L.5
Kim, Y.6
Minor, W.7
Rastinejad, F.8
Khorasanizadeh, S.9
-
67
-
-
33646438365
-
Recognition of histone H3lysine-4 methylation by the double tudor domain of JMJD2A
-
Huang Y, FangJ. Bedford MT et al. Recognition of histone H3lysine-4 methylation by the double tudor domain of JMJD2A. Science 2006; 312:748-751.
-
(2006)
Science
, vol.312
, pp. 748-751
-
-
Huang, Y.1
Fang, J.2
Bedford, M.T.3
-
68
-
-
33745809637
-
Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF
-
DOI 10.1038/nature04802, PII NATURE04802
-
Li H, Din S. WangW et al. Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF. Nature 2006; 442:91-95. (Pubitemid 44064215)
-
(2006)
Nature
, vol.442
, Issue.7098
, pp. 91-95
-
-
Li, H.1
Ilin, S.2
Wang, W.3
Duncan, E.M.4
Wysocka, J.5
Allis, C.D.6
Patel, D.J.7
-
69
-
-
33745818717
-
Molecular mechanism of histone H3K4me3 recognition by plant homeodomain of ING2
-
DOI 10.1038/nature04814, PII NATURE04814
-
Pena PV; Davrazou F, Shi X et al. Molecular mechanism of histone H3K4me3 recognition by plant homeodomain of ING2. Nature 2006; 442:100-103. (Pubitemid 44064217)
-
(2006)
Nature
, vol.442
, Issue.7098
, pp. 100-103
-
-
Pena, P.V.1
Davrazou, F.2
Shi, X.3
Walter, K.L.4
Verkhusha, V.V.5
Gozani, O.6
Zhao, R.7
Kutateladze, T.G.8
-
70
-
-
33745868054
-
ING2 PHD domain links histone H3 lysine 4 methylation to active gene repression
-
DOI 10.1038/nature04835, PII NATURE04835
-
Shi X, Hong T. Walter KL et al. ING2 PHD domain links histone H3 lysine 4 methylation to active gene repression. Nature 2006; 442:96-99. (Pubitemid 44064216)
-
(2006)
Nature
, vol.442
, Issue.7098
, pp. 96-99
-
-
Shi, X.1
Hong, T.2
Walter, K.L.3
Ewalt, M.4
Michishita, E.5
Hung, T.6
Carney, D.7
Pena, P.8
Lan, F.9
Kaadige, M.R.10
Lacoste, N.11
Cayrou, C.12
Davrazou, F.13
Saha, A.14
Cairns, B.R.15
Ayer, D.E.16
Kutateladze, T.G.17
Shi, Y.18
Cote, J.19
Chua, K.F.20
Gozani, O.21
more..
-
71
-
-
33745839365
-
A PHD finger of NURF couples histone H3 lysine 4 trimethylation with chromatin remodelling
-
DOI 10.1038/nature04815, PII NATURE04815
-
Wysocka J, Swigut T. Xiao H et al. A PHD finger ofNURF couples histone H31ysine 4 trimethylation with chromatin remodelling. Nature 2006; 442:86-90. (Pubitemid 44064214)
-
(2006)
Nature
, vol.442
, Issue.7098
, pp. 86-90
-
-
Wysocka, J.1
Swigut, T.2
Xiao, H.3
Milne, T.A.4
Kwon, S.Y.5
Landry, J.6
Kauer, M.7
Tackett, A.J.8
Chait, B.T.9
Badenhorst, P.10
Wu, C.11
Allis, C.D.12
-
72
-
-
33751527233
-
Yng1 PHD Finger Binding to H3 Trimethylated at K4 Promotes NuA3 HAT Activity at K14 of H3 and Transcription at a Subset of Targeted ORFs
-
DOI 10.1016/j.molcel.2006.10.026, PII S1097276506007325
-
Taverna SD, Ilin S. Rogers RS et al. Yngl PHD finger binding to H3 trimethylated at K4 promotes NuA3 HAT activity at K14 of H3 and transcription at a subset of targeted ORFs. Mol Cell 2006; 24:785-796. (Pubitemid 44839214)
-
(2006)
Molecular Cell
, vol.24
, Issue.5
, pp. 785-796
-
-
Taverna, S.D.1
Ilin, S.2
Rogers, R.S.3
Tanny, J.C.4
Lavender, H.5
Li, H.6
Baker, L.7
Boyle, J.8
Blair, L.P.9
Chait, BrianT.10
Patel, D.J.11
Aitchison, J.D.12
Tackett, A.J.13
Allis, C.D.14
-
73
-
-
33846019277
-
Methylation of Lysine 4 on Histone H3: Intricacy of Writing and Reading a Single Epigenetic Mark
-
DOI 10.1016/j.molcel.2006.12.014, PII S1097276506008720
-
Ruthenburg AJ, Allis CD. Wysocka J. Methylation of lysine 4 on histone H3 : intricacy of writing and reading a single epigenetic mark. Mol Cell 2007; 25:15-30. (Pubitemid 46049068)
-
(2007)
Molecular Cell
, vol.25
, Issue.1
, pp. 15-30
-
-
Ruthenburg, A.J.1
Allis, C.D.2
Wysocka, J.3
-
74
-
-
30944452960
-
The PHD finger, a nuclear protein-interaction domain
-
DOI 10.1016/j.tibs.2005.11.001, PII S0968000405003245
-
Bienz M, The PHD finger, a nuclear protein-interaction domain. Trends Biochem Sci 2006; 31:35-40. (Pubitemid 43117541)
-
(2006)
Trends in Biochemical Sciences
, vol.31
, Issue.1
, pp. 35-40
-
-
Bienz, M.1
-
75
-
-
33745713437
-
It takes a PHD to read the histone code
-
Mellor J, It takes a PHD to read the histone code. Cell 2006; 126:22-24.
-
(2006)
Cell
, vol.126
, pp. 22-24
-
-
Mellor, J.1
-
76
-
-
0031712128
-
The V(D)J recombination activating protein RAG2 consists of a six-bladed propeller and a PHD fingerlike domain, as revealed by sequence analysis
-
DOI 10.1007/s000180050216
-
Callebaut I, Momon JP. The V(D)J recombination activatingprotein RAG2 consistsofa six-bladed propeller and a PHD fingerlike domain, as revealed by sequence analysis. Cell Mol Life Sci 1998; 54:880-891. (Pubitemid 28425319)
-
(1998)
Cellular and Molecular Life Sciences
, vol.54
, Issue.8
, pp. 880-891
-
-
Callebaut, I.1
Mornon, J.-P.2
-
77
-
-
0033942616
-
Mutations in conserved regions of the predicted RAG2 kelch repeats block initiation of V(D)J recombination and result in primary immunodeficiencies
-
DOI 10.1128/MCB.20.15.5653-5664.2000
-
Gomez CA, Ptaszek LM. Villa A et al. Mutations in conserved regions of the predicted RAG2 kelch repeats block initiation of V(D)J recombination and result in primary immunodeficiencies. Mol Cell Biol 2000; 20:5653-5664. (Pubitemid 30482899)
-
(2000)
Molecular and Cellular Biology
, vol.20
, Issue.15
, pp. 5653-5664
-
-
Gomez, C.A.1
Ptaszek, L.M.2
Villa, A.3
Bozzi, F.4
Sobacchi, C.5
Brooks, E.G.6
Notarangelo, L.D.7
Spanopoulou, E.8
Pan, Z.Q.9
Vezzoni, P.10
Cortes, P.11
Santagata, S.12
-
78
-
-
0037105535
-
The immunophenotypic and immunogenotypic B-cell differentiation arrest in bone marrow of RAG-deficient SCID patients corresponds to residual recombination activities of mutated RAG proteins
-
Noordzij JG, de Bruin-Versteeg S. Verkaik NS ec at The immunophenorypic and immunogenotypic B-cell differentiation arrest in bone marrow of RAG-deficient SCID patients corresponds to residual recombination activities of mutated RAG proteins. Blood 2002; 100:2145-2152. (Pubitemid 35001250)
-
(2002)
Blood
, vol.100
, Issue.6
, pp. 2145-2152
-
-
Noordzij, J.G.1
De Bruin-Versteeg, S.2
Verkaik, N.S.3
Vossen, J.M.J.J.4
De Groot, R.5
Bernatowska, E.6
Langerak, A.W.7
Van Gent, D.C.8
Van Dongen, J.J.M.9
-
79
-
-
10144253125
-
RAG mutations in human B cell-negative SCID
-
DOI 10.1126/science.274.5284.97
-
Schwarz K, Gauss GH. Ludwig L et al. RAG mutations in human B-cell-negarive SCID. Science 1996; 274:97-99. (Pubitemid 26332732)
-
(1996)
Science
, vol.274
, Issue.5284
, pp. 97-99
-
-
Schwarz, K.1
Gauss, G.H.2
Ludwig, L.3
Pannicke, U.4
Li, Z.5
Lindner, D.6
Friedrich, W.7
Seger, R.A.8
Hansen-Hagge, T.E.9
Desiderio, S.10
Lieber, M.R.11
Bartram, C.R.12
-
80
-
-
0035161258
-
V(D)J recombination defects in lymphocytes due to RAG mutations: Severe immunodeficiency with a spectrum of clinical presentations
-
DOI 10.1182/blood.V97.1.81
-
Villa A, Sobacchi C. Notarangelo LD er at V(D)J recombination defects in lymphocytes due to RAG mutations: severe immunodeficiency with a spectrum of clinical presentations. Blood 2001; 97:81-88. (Pubitemid 32061245)
-
(2001)
Blood
, vol.97
, Issue.1
, pp. 81-88
-
-
Villa, A.1
Sobacchi, C.2
Notarangelo, L.D.3
Bozzi, F.4
Abinun, M.5
Abrahamsen, T.G.6
Arkwright, P.D.7
Baniyash, M.8
Brooks, E.G.9
Conley, M.E.10
Cortes, P.11
Duse, M.12
Fasth, A.13
Filipovich, A.M.14
Infante, A.J.15
Jones, A.16
Mazzolari, E.17
Muller, S.M.18
Pasic, S.19
Rechavi, G.20
Sacco, M.G.21
Santagata, S.22
Schroeder, M.L.23
Seger, R.24
Strina, D.25
Ugazio, A.26
Valiaho, J.27
Vihinen, M.28
Vogler, L.B.29
Ochs, H.30
Vezzoni, P.31
Friedrich, W.32
Schwarz, K.33
more..
-
81
-
-
0032577548
-
Partial V(D)J recombination activity leads to omenn syndrome
-
DOI 10.1016/S0092-8674(00)81448-8
-
Villa A, Santagata S. Bozzi F et al. Partial V(D)J recombination activity leads to Omenn syndrome. Cell 1998; 93:885-896. (Pubitemid 28257593)
-
(1998)
Cell
, vol.93
, Issue.5
, pp. 885-896
-
-
Villa, A.1
Santagata, S.2
Bozzi, F.3
Giliani, S.4
Frattini, A.5
Imberti, L.6
Gatta, L.B.7
Ochs, H.D.8
Schwarz, K.9
Notarangelo, L.D.10
Vezzoni, P.11
Spanopoulou, E.12
-
82
-
-
37649026007
-
The plant homeodomain finger of RAG2 recognizes histone H3 methylated at both lysine-4 and arginine-2
-
Ramon-Maiques S. Kuo AJ. Carney D et al. The plant homeodomain finger of RAG2 recognizes histone H3 methylated at both lysine-4 and arginine-2. Proc Natl Acad Sci USA 2007; 104:18993-18998.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 18993-18998
-
-
Ramon-Maiques, S.1
Kuo, A.J.2
Carney, D.3
-
83
-
-
23844471918
-
A direct interaction between the RAG2 C terminus and the core histones is required for efficient V(D)J recombination
-
DOI 10.1016/j.immuni.2005.07.004, PII S1074761305002360
-
West KL, Singha NC. De Ioannes P et al. A direct interaction between the RAG2 C terminus and the core histones is required for efficient V(D)J recombination. Immunity 2005; 23:203-212. (Pubitemid 41169289)
-
(2005)
Immunity
, vol.23
, Issue.2
, pp. 203-212
-
-
West, K.L.1
Singha, N.C.2
De Ioannes, P.3
Lacomis, L.4
Erdjument-Bromage, H.5
Tempst, P.6
Cortes, P.7
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