The immunophenotypic and immunogenotypic B-cell differentiation arrest in bone marrow of RAG-deficient SCID patients corresponds to residual recombination activities of mutated RAG proteins

Blood

Volumn 100, Issue 6, 2002, Pages 2145-2152

  Noordzij, Jeroen G ^a,b,c   De Bruin Versteeg, Sandra ^a,b,c   Verkaik, Nicole S ^a,b,c   Vossen, Jaak M J J ^a,b,c   De Groot, Ronald ^a,b,c   Bernatowska, Ewa ^a,b,c   Langerak, Anton W ^a,b,c   Van Gent, Dik C ^a,b,c   Van Dongen, Jacques J M ^a,b,c  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c CHILDREN'S MEMORIAL HEALTH INSTITUTE   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN M; RAG1 PROTEIN; RAG2 PROTEIN;

ARTICLE; B LYMPHOCYTE DIFFERENTIATION; CLINICAL ARTICLE; COMBINED IMMUNODEFICIENCY; ENZYME ACTIVITY; FLOW CYTOMETRY; GENE MUTATION; GENE REARRANGEMENT; HUMAN; HUMAN CELL; IMMUNOPHENOTYPING; NATURAL KILLER CELL; OMENN SYNDROME; PRIORITY JOURNAL; REACTION ANALYSIS;

B-LYMPHOCYTES; BONE MARROW CELLS; CASE-CONTROL STUDIES; CELL DIFFERENTIATION; CHILD, PRESCHOOL; DNA-BINDING PROTEINS; FAMILY HEALTH; FEMALE; FLOW CYTOMETRY; GENE REARRANGEMENT; GENES, IMMUNOGLOBULIN; GENOTYPE; HOMEODOMAIN PROTEINS; HUMANS; IMMUNOPHENOTYPING; INFANT; MALE; MUTATION; NUCLEAR PROTEINS; SEVERE COMBINED IMMUNODEFICIENCY;

EID: 0037105535     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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