Conformational selection or induced fit: A flux description of reaction mechanism

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 33, 2009, Pages 13737-13741

  Hammes, Gordon G ^a   Chang, Yu Chu ^a   Oas, Terrence G ^a  

^a DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Binding; Coupled equilibria; Folding; Kinetics; Mechanism

Indexed keywords

DIHYDROFOLATE REDUCTASE; FLAVINE MONONUCLEOTIDE; FLAVODOXIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

ARTICLE; ENZYME SUBSTRATE; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN STABILITY; PROTEIN TRANSPORT; PROTON NUCLEAR MAGNETIC RESONANCE; THERMOSTABILITY;

ALGORITHMS; CHEMISTRY; DESULFOVIBRIO DESULFURICANS; FLAVINS; KINETICS; LIGANDS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, CHEMICAL; MODELS, THEORETICAL; MOLECULAR CONFORMATION; NADP; PROTEIN CONFORMATION; PROTEIN FOLDING; TETRAHYDROFOLATE DEHYDROGENASE;

EID: 69549120472     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0907195106     Document Type: Article

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