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Biochemistry

Volumn 40, Issue 33, 2001, Pages 9846-9859

Backbone dynamics in dihydrofolate reductase complexes: Role of loop flexibility in the catalytic mechanism

(5) Osborne, M J a,b Schnell, J a Benkovic, S J c Dyson, H J a Wright, P E a

a SCRIPPS RESEARCH INSTITUTE (United States)

b NATIONAL RESEARCH COUNCIL CANADA (Canada)

c PENNSYLVANIA STATE UNIVERSITY (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACKBONE DYNAMICS;

CATALYSIS; ENZYMES; ESCHERICHIA COLI; GEOMETRY; HYDROGEN; POLYPEPTIDES;

BIOCHEMISTRY;

ADENOSINE; DIHYDROFOLATE REDUCTASE; FOLIC ACID; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

ANISOTROPY; ARTICLE; BINDING SITE; CATALYSIS; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME MECHANISM; ESCHERICHIA COLI; GEOMETRY; HYDROGEN BOND; MICHAELIS MENTEN KINETICS; MOLECULAR DYNAMICS; MOLECULAR MODEL; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; NUCLEAR OVERHAUSER EFFECT; PRIORITY JOURNAL;

BINDING SITES; CATALYSIS; DIFFUSION; ESCHERICHIA COLI; FOLIC ACID; HYDROGEN BONDING; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; METHIONINE; MODELS, CHEMICAL; MODELS, MOLECULAR; MODELS, STATISTICAL; MUTAGENESIS, SITE-DIRECTED; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; TETRAHYDROFOLATE DEHYDROGENASE;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 0035928796 PISSN: 00062960 EISSN: None Source Type: Journal
DOI: 10.1021/bi010621k Document Type: Article

Times cited : (234)

References (59)

1
- 0029782456
- (1996) Nat. Sruct. Biol. , vol.3 , pp. 821-833
- Cannon, W.R.¹ Singleton, S.F.² Benkovic, S.J.³

2
- 0040362704
- (2000) Biochemistry , vol.39 , pp. 6267-6274
- Bruice, T.C.¹ Benkovic, S.J.²

3
- 0032500555
- (1998) J. Biol. Chem. , vol.273 , pp. 26257-26260
- Cannon, W.R.¹ Benkovic, S.J.²

4
- 0029000872
- (1995) Biochemistry , vol.34 , pp. 8309-8319
- Williams, J.C.¹ McDermott, A.E.²

5
- 0029102089
- (1995) Biochemistry , vol.34 , pp. 11037-11048
- Epstein, D.M.¹ Benkovic, S.J.² Wright, P.E.³

6
- 0028049327
- (1994) Biochemistry , vol.33 , pp. 439-442
- Falzone, C.J.¹ Wright, P.E.² Benkovic, S.J.³

7
- 0028921302
- (1995) Nat. Struct. Biol. , vol.2 , pp. 274-280
- Nicholson, L.K.¹ Yamazaki, T.² Torchia, D.A.³ Grzesiek, S.⁴ Bax, A.⁵ Stahl, S.J.⁶ Kaufman, J.D.⁷ Wingfield, P.T.⁸ Lam, P.Y.S.⁹ Jadhav, P.K.¹⁰ Hodge, C.N.¹¹ Domaille, P.J.¹² Chang, C.-H.¹³

8
- 0025331920
- (1990) Biochemistry , vol.29 , pp. 6619-6625
- Lolis, E.¹ Petsko, G.A.²

9
- 0030877587
- (1997) Protein Sci. , vol.6 , pp. 1375-1386
- Rader, S.D.¹ Agard, D.A.²

10
- 0031015737
- (1997) Biochemistry , vol.36 , pp. 586-603
- Sawaya, M.R.¹ Kraut, J.²

11
- 0029908925
- (1996) Biochemistry , vol.35 , pp. 15129-15133
- Young, L.¹ Post, C.B.²

12
- 0030944408
- (1997) J. Am. Chem. Soc. , vol.119 , pp. 2386-2395
- Cannon, W.R.¹ Garrison, B.J.² Benkovic, S.J.³

13
- 0032482925
- (1998) Proc. Natl. Acad. Sci. U.S.A. , vol.95 , pp. 9280-9283
- Zhou, H.X.¹ Wlodek, S.T.² McCammon, J.A.³

14
- 0020698476
- (1983) Annu. Rev. Biochem. , vol.53 , pp. 263-300
- Karplus, M.¹ McCammon, J.A.²

15
- 0343307107
- (1997) Biophys. Chem. , vol.65 , pp. 1-28
- Kurzynski, M.¹

16
- 0032978685
- (1999) Biophys. J. , vol.77 , pp. 85-98
- Lau, E.Y.¹ Bruice, T.C.²

17
- 0023668190
- (1987) Biochemistry , vol.26 , pp. 4085-4092
- Fierke, C.A.¹ Johnson, K.A.² Benkovic, S.J.³

18
- 0026757079
- (1992) Biochemistry , vol.31 , pp. 7826-7833
- Li, L.¹ Falzone, C.J.² Wright, P.E.³ Benkovic, S.J.⁴

19
- 0031443372
- (1997) Biochemistry , vol.36 , pp. 15792-15800
- Cameron, C.E.¹ Benkovic, S.J.²

20
- 0032485865
- (1998) Biochemistry , vol.37 , pp. 6336-6342
- Miller, G.P.¹ Benkovic, S.J.²

21
- 0032485627
- (1998) Biochemistry , vol.37 , pp. 6327-6335
- Miller, G.P.¹ Benkovic, S.J.²

22
- 0033955055
- (2000) J. Am. Chem. Soc. , vol.122 , pp. 225-231
- Radkiewicz, J.L.¹ Brooks III, C.L.²

23
- 0035072684
- (2001) J. Biomol. NMR , vol.19 , pp. 209-230
- Osborne, M.J.¹ Wright, P.E.²

24
- 0028438718
- (1994) J. Biomol. NMR , vol.4 , pp. 349-366
- Falzone, C.J.¹ Cavanagh, J.² Cowart, M.³ Palmer III, A.G.⁴ Matthews, C.R.⁵ Benkovic, S.J.⁶ Wright, P.E.⁷

25
- 0028022578
- (1994) FEBS Lett. , vol.350 , pp. 87-90
- Lee, W.¹ Revington, M.J.² Arrowsmith, C.³ Kay, L.E.⁴

26
- 0029367044
- (1995) J. Biomol. NMR , vol.6 , pp. 153-162
- Farrow, N.A.¹ Zhang, O.² Szabo, A.³ Torchia, D.A.⁴ Kay, L.E.⁵

27
- 0000486802
- (1992) Mol. Phys. , vol.75 , pp. 699-711
- Palmer, A.G.¹ Skelton, N.J.² Chazin, W.J.³ Wright, P.E.⁴ Rance, M.⁵

28
- 0021132710
- (1984) J. Am. Chem. Soc. , vol.106 , pp. 6104-6105
- Live, D.H.¹ Davis, D.G.² Agosta, W.C.³ Cowburn, D.⁴

29
- 0010285919
- (1986) J. Magn. Reson. , vol.67 , pp. 565-569
- Bax, A.¹ Subramanian, S.²

30
- 0001076476
- (1993) J. Magn. Reson. Ser. A , vol.105 , pp. 219-222
- Zhu, G.¹ Torchia, D.A.² Bax, A.³

31
- 0029400480
- (1995) J. Biomol. NMR , vol.6 , pp. 277-293
- Delaglio, F.¹ Grzesiek, S.² Vuister, G.W.³ Guang, Z.⁴ Pfeifer, J.⁵ Bax, A.⁶

32
- 0001733173
- (1994) J. Chem. Phys. , vol.29 , pp. 1012-1014
- Johnson, B.A.¹ Blevins, R.A.²

33
- 0342976767
- (1989) J. Magn. Reson. , vol.84 , pp. 425-430
- Marion, D.¹ Ikura, M.² Bax, A.³

34
- 12044256620
- (1991) J. Am. Chem. Soc. , vol.113 , pp. 4371-4380
- Palmer, A.G.¹ Rance, M.² Wright, P.E.³

35
- 0026637797
- (1992) Biochemistry , vol.31 , pp. 4394-4406
- Stone, M.J.¹ Fairbrother, W.J.² Palmer III, A.G.³ Reizer, J.⁴ Saier M.H., Jr.⁵ Wright, P.E.⁶

36
- 0003943480
- Clarendon Press, Oxford
- (1961) Principles of Nuclear Magnetism
- Abragam, A.¹

37
- 0029900275
- (1996) J. Am. Chem. Soc. , vol.118 , pp. 6986-6991
- Tjandra, N.¹ Szabo, A.² Bax, A.³

38
- 0031111153
- (1997) J. Biomol. NMR , vol.9 , pp. 287-298
- Lee, L.K.¹ Rance, M.² Chazin, W.J.³ Palmer, A.G.⁴

39
- 0029029566
- (1995) Science , vol.268 , pp. 886-889
- Brüschweiler, R.¹ Liao, X.² Wright, P.E.³

40
- 0032511359
- (1998) J. Am. Chem. Soc. , vol.120 , pp. 7905-7915
- Kroenke, C.D.¹ Loria, J.P.² Lee, L.P.³ Rance, M.⁴ Palmer III, A.G.⁵

41
- 0025046144
- (1990) J. Am. Chem. Soc. , vol.112 , pp. 4989-4991
- Clore, G.M.¹ Szabo, A.² Bax, A.³ Kay, L.E.⁴ Driscoll, P.C.⁵ Gronenborn, A.M.⁶

42
- 0030445011
- (1996) Biochemistry , vol.35 , pp. 16009-16023
- Mandel, A.M.¹ Akke, M.² Palmer III, A.G.³

43
- 0031616834
- (1998) J. Biomol. NMR , vol.11 , pp. 17-29
- Zhu, L.¹ Dyson, H.J.² Wright, P.E.³

44
- 0030932089
- (1997) J. Am. Chem. Soc. , vol.119 , pp. 2915-2920
- Wei, A.¹ Raymond, M.K.² Roberts, J.D.³

45
- 33646719091
- (1982) J. Am. Chem. Soc. , vol.104 , pp. 4546-4559
- Lipari, G.¹ Szabo, A.²

46
- 33845553743
- (1982) J. Am. Chem. Soc. , vol.104 , pp. 4559-4570
- Lipari, G.¹ Szabo, A.²

47
- 0026065644
- (1991) Biochemistry , vol.30 , pp. 2227-2239
- Bystroff, C.¹ Kraut, J.²

48
- 0034710950
- (2000) Proc. Natl. Acad. Sci. U.S.A. , vol.97 , pp. 12020-12025
- Pan, H.¹ Lee, J.C.² Hilser, V.J.³

49
- 0004320231
- Ph.D. Thesis, The Pennsylvania State University, State College
- (1997)
- Miller, G.P.¹

50
- 0025989451
- (1991) Biochemistry , vol.30 , pp. 7801-7809
- Ahrweiler, P.¹ Frieden, C.²

51
- 0035969953
- (2001) Biochemistry , vol.40 , pp. 867-875
- Miller, G.P.¹ Wahnon, D.C.² Benkovic, S.J.³

52
- 0033566242
- (1999) Nature , vol.400 , pp. 289-293
- Feher, V.A.¹ Cavanagh, J.²

53
- 0035937443
- (2001) Science , vol.291 , pp. 2429-2433
- Volkman, B.F.¹ Lipson, D.² Wemmer, D.E.³ Kern, D.⁴

54
- 0035901519
- (2001) Biochemistry , vol.40 , pp. 4590-4600
- Loh, A.P.¹ Pawley, N.² Nicholson, L.K.³ Oswald, R.E.⁴

55
- 0034283867
- (2000) Trends Biochem. Sci. , vol.25 , pp. 405-408
- Sutcliffe, M.J.¹ Scrutton, N.S.²

56
- 0033200247
- (1999) Struct. Fold. Des. , vol.7 , pp. 1047-1055
- Ishima, R.¹ Freedberg, D.I.² Wang, Y.X.³ Louis, J.M.⁴ Torchia, D.A.⁵

57
- 0034619511
- (2000) Biochemistry , vol.39 , pp. 13356-13364
- Huntley, J.J.A.¹ Scrofani, S.D.B.² Osborne, M.J.³ Wright, P.E.⁴ Dyson, H.J.⁵

58
- 0026319199
- (1991) Proteins , vol.11 , pp. 281-296
- Nicholls, A.¹ Sharp, K.A.² Honig, B.³

59
- 0029881007
- (1996) J. Mol. Graphics , vol.14 , pp. 51-55
- Koradi, R.¹ Billeter, M.² Wüthrich, K.³

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