Nuclear-receptor ligands and ligand-binding domains

Annual Review of Biochemistry

Volumn 68, Issue , 1999, Pages 559-581

  Weatherman, Ross V ^a   Fletterick, Robert J ^a,b   Scanlan, Thomas S ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Hormone agonists antagonists; Intracellular receptors; Intracellular signaling; Steroid thyroid hormone receptors; Transcriptional regulation

Indexed keywords

ALITRETINOIN; CELL NUCLEUS RECEPTOR; ESTROGEN RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PROGESTERONE RECEPTOR; THYROID HORMONE RECEPTOR;

HORMONE PROTEIN COMPLEX; HORMONE TRANSPORT; INTRACELLULAR TRANSPORT; LIGAND BINDING; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; RECEPTOR AFFINITY; REVIEW; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION; TRANSCRIPTION REGULATION;

LIGANDS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0032867623     PISSN: 00664154     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.biochem.68.1.559     Document Type: Review

References (110)

1. Mangelsdorf DJ, Thummel C, Beato M, Herrlich P, Schutz G, et al. 1995. Cell 83:835-39
2. Chemerda J, Chamberlin E, Wilson E, Tishler M. 1951. J. Am. Chem. Soc. 73:4052
3. Rosenkranz G, Pataki J, Djerassi C. 1951. J. Am. Chem. Soc. 73:4055
4. Woodward R, Sandheimer F, Taub D. 1951. J. Am. Chem. Soc. 73:4057
5. Evans RM. 1988. Science 240:889-95
6. Robertson D, Willy P, Heyman R, Mangelsdorf D. 1997. In Nuclear Orphan Receptors: Scientific Progress and Therapeutic Opportunities, ed. J Bristol, pp. 251-60. New York: Academic
7. Enmark E, Gustafsson J-Å. 1996. Mol. Endocrinol. 10:1293-307
8. Chambon P. 1996. FASEB J. 10:940-54
9. Gustafsson J-Å. 1997. Nat. Med. 3:493-94
10. Lazar MA. 1993. Endocr. Rev. 14:184-93
11. Patch K, Webb P, Kuiper GGJM, Nilsson S, Gustafsson J-Å, et al. 1997. Science 277:1508-10
12. Dawson MI, Chao WR, Pine P, Jong L, Hobbs PD, et al. 1995. Cancer Res. 55:4446-51
13. Charpentier B, Bernardon JM, Eustache J, Millois C, Martin B, et al. 1995. J. Med. Chem. 38:4993-5006
14. Taneja R, Roy B, Plassat JL, Zusi CF, Ostrowski J, et al. 1996. Proc. Natl. Acad. Sci. USA 93:6197-202
15. Chiellini G, Apriletti JW, Yoshihara HA, Baxter JD, Ribeiro RCJ, et al. 1998. Chem. Biol. 5:299-306
16. Tsai MJ, O' Malley BW. 1994. Annu. Rev. Biochem. 63:451-86
17. Ribeiro RCJ, Kushner PJ, Baxter JD. 1995. Annu. Rev. Med. 46:443-53
18. Moras D, Gronemeyer H. 1998. Curr. Opin. Cell Biol. 10:384-91
19. Katzenellenbogen JA, Katzenellenbogen BS. 1996. Chem. Biol. 3:529-36
20. Pratt WB, Toft DO. 1997. Endocr. Rev. 18:06-60
21. Wolffe AP. 1997. Nature 387:16-17
22. Pazin MJ, Kadonaga JT. 1997. Cell 89:325-28
23. Torchia J, Glass C, Rosenfeld MG. 1998. Curr. Opin. Cell Biol. 10:373-83
24. Lees JA, Fawell SE, Parker MG. 1989. Nuc. Acid Res. 17:5477-88
25. Tora L, White J, Brou C, Tasset D, Webster N, et al. 1989. Cell 59:477-87
26. Danielsen M, Northrop JP, Jonklass J, Ringold GM. 1987. Mol. Endocrinol. 1:816-22
27. Zilliacus J, Wright APH, Carlstedt-Duke J, Gustafsson J-Å. 1995. Mol. Endocrinol. 9:389-400
28. Härd T, Kellenbach E, Buelens R, Maler BA, Dahlman K, et al. 1990. Science 249:157-60
29. Luisi BF, Xu WX, Otwinowski Z, Freedman LB, Yamamoto KR, et al. 1991. Nature 352:458-61
30. Kumar V, ChambonP. 1988. Cell 55:145-56
31. Lefstin JA, Yamamoto KR. 1998. Nature 392:885-88
32. Gottlicher M, Heck S, HerrlichP. 1998.J. Mol. Med. 76:480-89
33. Pfahl M. 1993. Endocr. Rev. 14:651-58
34. Webb P, Lopez GN, Uht RM, Kushner PJ. 1995. Mol. Endocrinol. 9:443-56
35. Yang-Yen HF, Chambard JC, Sun YL, Smeal T, Schmidt TJ, et al. 1990. Cell 62:1205-15
36. Starr DB, Matsui W, Thomas JR, Yamamoto KR. 1996. Genes Dev. 10:1271-83
37. Liden J, Delaunay F, Rafter I, Gustafsson J-Å, Okret S. 1997. J. Biol. Chem. 272:21467-72
38. Heck S, Kullmann M, Gast A, Ponta H, Rahmsdorf HJ, et al. 1994. EMBO J. 13:4087-95
39. Jackson TA, Richer JK, Bain DL, Takimoto GS, Tung L, et al. 1997. Mol. Endocrinol. 11:693-705
40. Montano MM, Muller V, Trobaugh A, Katzenellenbogen BS. 1995. Mol. Endocrinol. 9:814-25
41. Forman BM, Tontonoz P, Chen J, Brun RP. Spiegelman BM, et al. 1995. Cell 83:803-12
42. Kliewer SA, Lenhard JM, Willson TM, Patel I, Morris DC, et al. 1995. Cell 83:813-19
43. Janowski BA, Willy PJ, Devi TR, Falck JR, Mangelsdorf DJ. 1996. Nature 383:728-31
44. Ribeiro RCJ, Cavalieri RR, Lomri N, Rahmaoui CM, Baxter JD, et al. 1996. J. Biol. Chem. 271:17147-51
45. Kralli A, Bohen SP, Yamamoto KR. 1995. Proc. Natl. Acad. Sci. USA 92:4701-5
46. Bogan AA, Cohen FE, Scanlan TS. 1998. Nat. Struct. Biol. 5:679-81
47. Jorgenson EC. 1978. In Thyroid Hormones, ed. CH Li, pp. 108-204. New York: Academic
48. MacGregor JI, Jordan VC. 1998. Pharmacol. Rev. 50:151-96
49. Rosen J, Day A, Jones TK, Jones ETT, Nadzan AM, et al. 1995. J. Med. Chem. 38:4855-74
50. Brzozowski AM, Pike ACW, Dauter Z, Hubbard RE, Bonn T, et al. 1997. Nature 389:753-58
51. Gustafsson J-Å. 1998. Curr. Opin. Chem. Biol. 2:508-11
52. Katzenellenbogen JA, O'Malley BW, Katzenellenbogen BS. 1996. Mol. Endocrinol. 10:119-31
53. Xu JM, Nawaz Z, Tsai SY, Tsai MJ, O'Malley BW. 1996. Proc. Natl. Acad. Sci. USA 93:12195-99
54. Smith CL, Nawaz Z, O'Malley BW. 1997. Mol. Endocrinol. 11:657-66
55. Lavinsky RM, Jepsen K, Heinzel T, Torchia J, Mullen TM, et al. 1998. Proc. Natl. Acad. Sci. USA 95:2920-25
56. Weigel NL. 1996. Biochem. J. 319:657-67
57. Wagner RL, Apriletti JW, MCGrath ME, West BL, Baxter JD, et al. 1995. Nature 378:690-97
58. Renaud JP, Rochel N, Ruff M, Vivat V, Chambon P, et al. 1995. Nature 378:681-89
59. Tanenbaum DM, Wang Y, Williams SP, Sigler PB. 1998. Proc. Natl. Acad. Sci. USA 95:5998-6003
60. Williams SP, Sigler PB. 1998. Nature 393:392-96
61. Nolte R, Wisely G, Westin S, Cobb J, Lambert M, et al. 1998. Nature 395:137-43
62. Bourguet W, Ruff M, Chambon P, Gronemeyer H, Moras D. 1995. Nature 375:377-82
63. Lin BC, Hong SH, Krig S, Yoh SM, Privalsky ML. 1997. Mol. Cell. Biol. 17:6131-38
64. Leid M. 1994. J. Biol. Chem. 269:14175-81
65. Leng XH, Blanco J, Tsai SY, Ozato K, O'Malley BW, et al. 1995. Mol. Cell. Biol. 15:255-63
66. Beekman JM, Allan GF, Tsai SY, Tsai MJ, O'Malley BW. 1993. Mol. Endocrinol. 7:1266-74
67. Allan GF, Leng XH, Tsai SY, Weigel NL, Edwards DP, et al. 1992. J. Biol. Chem. 267:19513-20
68. Zhang XK, Salbert G, Lee MO, Pfahl M. 1994. Mol. Cell. Biol. 14:4311-23
69. Klaholz BP, Renaud JP, Mitschler A, Zusi C, Chambon P, et al. 1998. Nat. Struct. Biol. 5:199-202
70. Levenson AS, Jordan VC. 1998. Cancer Res. 58:1872-75
71. Lanz RB, Rusconi S. 1994. Endocrinology 135:2183-95
72. Jenster G, Vanderkorput H, Vanvroonhoven C, Vanderkwast TH, Trapman J, et al. 1991. Mol. Endocrinol. 5:1396-404
73. Zhang SM, Liang XY, Danielsen M. 1996. Mol. Endocrinol. 10:24-34
74. Vegeto E, Allan GF, Schrader WT, Tsai MJ, McDonnell DP, et al. 1992. Cell 69:703-13
75. Klotzbucher M, Schwerk C, Holewa B, KleinHitpass L. 1997. Mol. Endocrinol. 11:768-78
76. Aufliegner M, Helmer E, Casanova J, Raaka BM, Samuels HH. 1993. Mol. Cell. Biol. 13:5725-37
77. Durand B, Saunders M, Gaudon C, Roy B, Losson R, et al. 1994. EMBO J. 13:5370-82
78. Fawell SE, Lees JA, White R, Parker MG. 1990. Cell 60:953-62
79. Giguère V, Hollenberg SM, Rosenfeld MG, Evans RM. 1986. Cell 46:645-52
80. Lee MS, Kliewer SA, Provencal J, Wright PE, Evans RM. 1993. Science 260:1117-21
81. Schwabe JW, Neuhaus D, Rhodes D. 1990. Nature 348:458-61
82. Lundbäck T, Zilliacus J, Gustafsson J-Å, Carlstedt-Duke J, Härd T. 1994 Biochemistry 33:5955-65
83. Härd T, Dahlman K, Carlstedt-Duke J, Gustafsson J-Å, Rigler R. 1990. Biochemistry 29:5358-64
84. Diamond MI, Miner JN, Yoshinaga SK, Yamamoto KR. 1990. Science 249:1266-72
85. Westin S, Kurokawa R, Nolte R, Wisley G, McInerney E, et al. 1998. Nature 395:199-202
86. Rodriguez R, Weigel NL, O'Malley BW, Schrader WT. 1990. Mol. Endocrinol. 4:1782-90
87. Allan GF, Tsai SY, Tsai MJ, O'Malley BW. 1992. Proc. Natl. Acad. Sci. USA 89:11750-54
88. Wilson TE, Fahrner TJ, Milbrandt J. 1993. Mol. Cell. Biol. 13:5794-804
89. Horwitz KB, Jackson TA, Rain DL, Richer JK, Takimoto GS, et al. 1996. Mol. Endocrinol. 10:1167-77
90. Wurtz JM, Bourguet W, Renaud JP, Vivat V, Chambon P, et al. 1996. Nat. Struct. Biol. 3:87-94
91. Ledouarin B, Baur EV, Zechel C, Heery D, Heine M, et al. 1996. Philos. Trans. R. Soc. London Ser. B 351:569-78
92. Jeyakumar M, Tanen MR, Bagchi MK. 1997. Mol. Endocrinol. 11:755-67
93. Henttu PMA, Kalkhoven E, Parker MG. 1997. Mol. Cell. Biol. 17:1832-39
94. Thenot S, Henriquet C, Rochefort H, Cavailles V. 1997. J. Biol. Chem. 272:12062-68
95. Feng WJ, Ribeiro RCJ, Wagner RL, Nguyen H, Apriletti JW, et al. 1998. Science 280:1747-49
96. Darimont B, Wagner R, Apriletti J, Stallcup M, Kushner P, et al. 1998. Genes Dev. 12:3343-56
97. Horlein AJ, Naar AM, Heinzel T, Torchia J, Gloss B, et al. 1995. Nature 377:397-404
98. Chen JD, Evans RM. 1995. Nature 377:454-57
99. Zhang X, Jeyakumar M, Petukhov S, Bagchi MK. 1998. Mol. Endocrinol. 12:513-24
100. Li H, Leo C, Schroen DJ, Chen JD. 1997. Mol. Endocrinol. 11:2025-37
101. Grese TA, Pennington LD, Sluka JP, Adrian MD, Cole HW, et al. 1998. J. Med. Chem. 41:1272-83
102. Shiau AK, Barstad D, Loria PM, Cheng L, Kusher PJ, et al. 1998. Cell 95:927-37
103. Ribeiro RCJ, Apriletti JW, Wagner RL, Feng WJ, Kushner PJ, et al. 1998. J. Steroid Biochem. Mol. Biol. 65:133-41
104. Resche-Rigon M, Gronemeyer H. 1998. Curr. Opin. Chem. Biol. 2:501-7
105. Ostrowski J, Roalsvig T, Hammer L, Marinier A, Starrett JE, et al. 1998. J. Biol. Chem. 273:3490-95
106. Vayssiere BM, Dupont S, Choquart A, Petit F, Garcia T, et al. 1997. Mol. Endocrinol. 11:1245-55
107. Fanjul A, Dawson MI, Hobbs PD, Jong L, Cameron JF, et al. 1994. Nature 372:107-11
108. Reichardt HM, Kaestner KH, Tuckermann J, Kretz O, Wessely O, et al. 1998. Cell 93:531-41
109. Ferrin T, Huang C, Jarvis L, Langridge R. 1988. J. Mol. Graph. 6:13-27
110. Huang CC, Pettersen EF, Klein TE, Ferrin TE, Langridge R. 1991. J. Mol. Graph. 9:230-36