Enzymes with lid-gated active sites must operate by an induced fit mechanism instead of conformational selection

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 37, 2008, Pages 13829-13834

  Sullivan, Sarah M ^a   Holyoak, Todd ^a  

^a UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

Author keywords

Enzyme dynamics; Phosphoenolpyruvate carboxykinase; Population shift

Indexed keywords

ENZYME; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP);

ARTICLE; CATALYSIS; ENERGY; ENZYME ACTIVE SITE; ENZYME CONFORMATION; PRIORITY JOURNAL;

ANIMALS; BINDING SITES; CATALYSIS; GUANOSINE TRIPHOSPHATE; MANGANESE; MODELS, MOLECULAR; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RATS; SUBSTRATE SPECIFICITY; THERMODYNAMICS;

EID: 52949089027     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0805364105     Document Type: Article

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