Binding-induced folding of a natively unstructured transcription factor

PLoS Computational Biology

Volumn 4, Issue 4, 2008, Pages

  Turjanski, Adrian Gustavo ^a   Gutkind, J Silvio ^a   Best, Robert B ^b,c   Hummer, Gerhard ^b  

^a NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

TOPOLOGY; TRANSCRIPTION;

BINDING MECHANISMS; CENTRAL COMPONENT; COACTIVATORS; FOLDING MECHANISM; FOLDINGS; GENES EXPRESSION; HUMAN TRANSCRIPTION FACTORS; REGULATORY NETWORK; TARGET BINDING; TRANSITION PATHS;

TRANSCRIPTION FACTORS;

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; TRANSCRIPTION FACTOR; CREBBP PROTEIN, HUMAN;

ARTICLE; BINDING KINETICS; MOLECULAR RECOGNITION; NUCLEAR MAGNETIC RESONANCE; PHASE TRANSITION; PREDICTION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN ISOLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEIN TARGETING; SIMULATION; STRUCTURE ANALYSIS; X RAY CRYSTALLOGRAPHY; AMINO ACID SEQUENCE; BINDING SITE; CHEMICAL MODEL; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER SIMULATION; HUMAN; METHODOLOGY; MOLECULAR GENETICS; PROTEIN TERTIARY STRUCTURE; SEQUENCE ANALYSIS; ULTRASTRUCTURE;

AMINO ACID SEQUENCE; BINDING SITES; COMPUTER SIMULATION; CREB-BINDING PROTEIN; HUMANS; MODELS, CHEMICAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; SEQUENCE ANALYSIS, PROTEIN; TRANSCRIPTION FACTORS;

EID: 42949161558     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1000060     Document Type: Article

References (71)