Single-molecule and transient kinetics investigation of the interaction of dihydrofolate reductase with NADPH and dihydrofolate

Proceedings of the National Academy of Sciences of the United States of America

Volumn 101, Issue 9, 2004, Pages 2764-2769

  Zhang, Zhiquan ^a   Rajagopalan, P T Ravi ^b   Selzer, Tzvia ^b   Benkovic, Stephen J ^b   Hammes, Gordon G ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ENZYME; DIHYDROFOLATE REDUCTASE; DIHYDROFOLIC ACID; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

ARTICLE; BIOSYNTHESIS; CATALYSIS; CHEMICAL REACTION; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME SUBSTRATE COMPLEX; ESCHERICHIA COLI; FLUORESCENCE; NONHUMAN; PRIORITY JOURNAL;

ESCHERICHIA COLI; FOLIC ACID; KINETICS; MODELS, BIOLOGICAL; NADP; TETRAHYDROFOLATE DEHYDROGENASE; TIME FACTORS;

ALEXA; BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 1542327706     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0400091101     Document Type: Article

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