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Volumn 204, Issue 2, 2009, Pages 282-294

Prepulse inhibition and genetic mouse models of schizophrenia

Author keywords

Mouse models; Prepulse inhibition; Schizophrenia; Startle

Indexed keywords

4 AMINOBUTYRIC ACID; ATYPICAL ANTIPSYCHOTIC AGENT; BENZODIAZEPINE DERIVATIVE; CLOZAPINE; DISRUPTED IN SCHIZOPHRENIA 1 PROTEIN; DOPAMINE; DOPAMINE 2 RECEPTOR BLOCKING AGENT; DOPAMINE TRANSPORTER; GENE PRODUCT; GLUTAMIC ACID; GLYCINE; METABOTROPIC RECEPTOR; MUTANT PROTEIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NEU DIFFERENTIATION FACTOR; NEUROLEPTIC AGENT; PROTEIN HOMER; QUETIAPINE; RACLOPRIDE; SEROTONIN UPTAKE INHIBITOR; UNCLASSIFIED DRUG; VOLINANSERIN;

EID: 69249214145     PISSN: 01664328     EISSN: 18727549     Source Type: Journal    
DOI: 10.1016/j.bbr.2009.04.021     Document Type: Article
Times cited : (174)

References (219)
  • 1
    • 0037401922 scopus 로고    scopus 로고
    • Low dose ketamine increases prepulse inhibition in healthy men
    • Abel K.M., Allin M.P., Hemsley D.R., and Geyer M.A. Low dose ketamine increases prepulse inhibition in healthy men. Neuropharmacology 44 (2003) 729-737
    • (2003) Neuropharmacology , vol.44 , pp. 729-737
    • Abel, K.M.1    Allin, M.P.2    Hemsley, D.R.3    Geyer, M.A.4
  • 2
    • 33746733526 scopus 로고    scopus 로고
    • Behavioral and biochemical characterization of a mutant mouse strain lacking d-amino acid oxidase activity and its implications for schizophrenia
    • Almond S.L., Fradley R.L., Armstrong E.J., Heavens R.B., Rutter A.R., Newman R.J., et al. Behavioral and biochemical characterization of a mutant mouse strain lacking d-amino acid oxidase activity and its implications for schizophrenia. Mol Cell Neurosci 32 (2006) 324-334
    • (2006) Mol Cell Neurosci , vol.32 , pp. 324-334
    • Almond, S.L.1    Fradley, R.L.2    Armstrong, E.J.3    Heavens, R.B.4    Rutter, A.R.5    Newman, R.J.6
  • 3
    • 0034548876 scopus 로고    scopus 로고
    • Dendritic and axonal targeting of type 5 metabotropic glutamate receptor is regulated by homer1 proteins and neuronal excitation
    • Ango F., Pin J.P., Tu J.C., Xiao B., Worley P.F., Bockaert J., et al. Dendritic and axonal targeting of type 5 metabotropic glutamate receptor is regulated by homer1 proteins and neuronal excitation. J Neurosci 20 (2000) 8710-8716
    • (2000) J Neurosci , vol.20 , pp. 8710-8716
    • Ango, F.1    Pin, J.P.2    Tu, J.C.3    Xiao, B.4    Worley, P.F.5    Bockaert, J.6
  • 4
    • 0036703884 scopus 로고    scopus 로고
    • Severe impairment of nmda receptor function in mice carrying targeted point mutations in the glycine binding site results in drug-resistant nonhabituating hyperactivity
    • Ballard T.M., Pauly-Evers M., Higgins G.A., Ouagazzal A.-M., Mutel V., Borroni E., et al. Severe impairment of nmda receptor function in mice carrying targeted point mutations in the glycine binding site results in drug-resistant nonhabituating hyperactivity. J Neurosci 22 (2002) 6713-6723
    • (2002) J Neurosci , vol.22 , pp. 6713-6723
    • Ballard, T.M.1    Pauly-Evers, M.2    Higgins, G.A.3    Ouagazzal, A.-M.4    Mutel, V.5    Borroni, E.6
  • 5
    • 0842264904 scopus 로고    scopus 로고
    • The selective serotonin-2a receptor antagonist m100907 reverses behavioral deficits in dopamine transporter knockout mice
    • Barr A.M., Lehmann-Masten V., Paulus M., Gainetdinov R.R., Caron M.G., and Geyer M.A. The selective serotonin-2a receptor antagonist m100907 reverses behavioral deficits in dopamine transporter knockout mice. Neuropsychopharmacology 29 (2004) 221-228
    • (2004) Neuropsychopharmacology , vol.29 , pp. 221-228
    • Barr, A.M.1    Lehmann-Masten, V.2    Paulus, M.3    Gainetdinov, R.R.4    Caron, M.G.5    Geyer, M.A.6
  • 6
    • 0030947083 scopus 로고    scopus 로고
    • Parvalbumin-immunoreactive neurons are reduced in the prefrontal cortex of schizophrenics
    • Beasley C.L., and Reynolds G.P. Parvalbumin-immunoreactive neurons are reduced in the prefrontal cortex of schizophrenics. Schizophr Res 24 (1997) 349-355
    • (1997) Schizophr Res , vol.24 , pp. 349-355
    • Beasley, C.L.1    Reynolds, G.P.2
  • 7
    • 0036792159 scopus 로고    scopus 로고
    • Selective deficits in prefrontal cortical gabaergic neurons in schizophrenia defined by the presence of calcium-binding proteins
    • Beasley C.L., Zhang Z.J., Patten I., and Reynolds G.P. Selective deficits in prefrontal cortical gabaergic neurons in schizophrenia defined by the presence of calcium-binding proteins. Biol Psychiatry 52 (2002) 708-715
    • (2002) Biol Psychiatry , vol.52 , pp. 708-715
    • Beasley, C.L.1    Zhang, Z.J.2    Patten, I.3    Reynolds, G.P.4
  • 8
    • 0034098525 scopus 로고    scopus 로고
    • Emerging principles of altered neural circuitry in schizophrenia
    • Benes F.M. Emerging principles of altered neural circuitry in schizophrenia. Brain Res Brain Res Rev 31 (2000) 251-269
    • (2000) Brain Res Brain Res Rev , vol.31 , pp. 251-269
    • Benes, F.M.1
  • 9
    • 0035007327 scopus 로고    scopus 로고
    • Gabaergic interneurons: implications for understanding schizophrenia and bipolar disorder
    • Benes F.M., and Berretta S. Gabaergic interneurons: implications for understanding schizophrenia and bipolar disorder. Neuropsychopharmacology 25 (2001) 1-27
    • (2001) Neuropsychopharmacology , vol.25 , pp. 1-27
    • Benes, F.M.1    Berretta, S.2
  • 10
    • 0032527572 scopus 로고    scopus 로고
    • A reduction of nonpyramidal cells in sector ca2 of schizophrenics and manic depressives
    • Benes F.M., Kwok E.W., Vincent S.L., and Todtenkopf M.S. A reduction of nonpyramidal cells in sector ca2 of schizophrenics and manic depressives. Biol Psychiatry 44 (1998) 88-97
    • (1998) Biol Psychiatry , vol.44 , pp. 88-97
    • Benes, F.M.1    Kwok, E.W.2    Vincent, S.L.3    Todtenkopf, M.S.4
  • 11
    • 0030331175 scopus 로고    scopus 로고
    • Up-regulation of gabaa receptor binding on neurons of the prefrontal cortex in schizophrenic subjects
    • Benes F.M., Vincent S.L., Marie A., and Khan Y. Up-regulation of gabaa receptor binding on neurons of the prefrontal cortex in schizophrenic subjects. Neuroscience 75 (1996) 1021-1031
    • (1996) Neuroscience , vol.75 , pp. 1021-1031
    • Benes, F.M.1    Vincent, S.L.2    Marie, A.3    Khan, Y.4
  • 12
    • 33745958262 scopus 로고    scopus 로고
    • Increased prepulse inhibition of the acoustic startle response is associated with better strategy formation and execution times in healthy males
    • Bitsios P., Giakoumaki S.G., Theou K., and Frangou S. Increased prepulse inhibition of the acoustic startle response is associated with better strategy formation and execution times in healthy males. Neuropsychologia 44 (2006) 2494-2499
    • (2006) Neuropsychologia , vol.44 , pp. 2494-2499
    • Bitsios, P.1    Giakoumaki, S.G.2    Theou, K.3    Frangou, S.4
  • 13
    • 0034927864 scopus 로고    scopus 로고
    • Schizophrenia and affective disorders-cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: clinical and p300 findings in a family
    • Blackwood D.H., Fordyce A., Walker M.T., St Clair D.M., Porteous D.J., and Muir W.J. Schizophrenia and affective disorders-cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: clinical and p300 findings in a family. Am J Hum Genet 69 (2001) 428-433
    • (2001) Am J Hum Genet , vol.69 , pp. 428-433
    • Blackwood, D.H.1    Fordyce, A.2    Walker, M.T.3    St Clair, D.M.4    Porteous, D.J.5    Muir, W.J.6
  • 14
    • 34248175418 scopus 로고    scopus 로고
    • Heterozygous neuregulin 1 mice are more sensitive to the behavioural effects of delta9-tetrahydrocannabinol
    • Boucher A.A., Arnold J.C., Duffy L., Schofield P.R., Micheau J., and Karl T. Heterozygous neuregulin 1 mice are more sensitive to the behavioural effects of delta9-tetrahydrocannabinol. Psychopharmacology (Berl) 192 (2007) 325-336
    • (2007) Psychopharmacology (Berl) , vol.192 , pp. 325-336
    • Boucher, A.A.1    Arnold, J.C.2    Duffy, L.3    Schofield, P.R.4    Micheau, J.5    Karl, T.6
  • 15
    • 0013952056 scopus 로고
    • Psychedelic experiences in acute psychoses
    • Bowers Jr. M.B., and Freedman D.X. Psychedelic experiences in acute psychoses. Arch Gen Psychiatry 15 (1966) 240-248
    • (1966) Arch Gen Psychiatry , vol.15 , pp. 240-248
    • Bowers Jr., M.B.1    Freedman, D.X.2
  • 17
    • 33746902947 scopus 로고    scopus 로고
    • Genetic inactivation of the nmda receptor nr2a subunit has anxiolytic- and antidepressant-like effects in mice
    • Boyce-Rustay J.M., and Holmes A. Genetic inactivation of the nmda receptor nr2a subunit has anxiolytic- and antidepressant-like effects in mice. Neuropsychopharmacology 31 (2006) 2405-2414
    • (2006) Neuropsychopharmacology , vol.31 , pp. 2405-2414
    • Boyce-Rustay, J.M.1    Holmes, A.2
  • 18
    • 33845870419 scopus 로고    scopus 로고
    • Deconstructing schizophrenia: an overview of the use of endophenotypes in order to understand a complex disorder
    • Braff D.L., Freedman R., Schork N.J., and Gottesman I.I. Deconstructing schizophrenia: an overview of the use of endophenotypes in order to understand a complex disorder. Schizophr Bull 33 (2007) 21-32
    • (2007) Schizophr Bull , vol.33 , pp. 21-32
    • Braff, D.L.1    Freedman, R.2    Schork, N.J.3    Gottesman, I.I.4
  • 19
    • 0034891977 scopus 로고    scopus 로고
    • Human studies of prepulse inhibition of startle: normal subjects, patient groups, and pharmacological studies
    • Braff D.L., Geyer M.A., and Swerdlow N.R. Human studies of prepulse inhibition of startle: normal subjects, patient groups, and pharmacological studies. Psychopharmacology (Berl) 156 (2001) 234-258
    • (2001) Psychopharmacology (Berl) , vol.156 , pp. 234-258
    • Braff, D.L.1    Geyer, M.A.2    Swerdlow, N.R.3
  • 20
    • 34247615035 scopus 로고    scopus 로고
    • Prepulse inhibition and p50 suppression are both deficient but not correlated in schizophrenia patients
    • Braff D.L., Light G.A., and Swerdlow N.R. Prepulse inhibition and p50 suppression are both deficient but not correlated in schizophrenia patients. Biol Psychiatry 61 (2007) 1204-1207
    • (2007) Biol Psychiatry , vol.61 , pp. 1204-1207
    • Braff, D.L.1    Light, G.A.2    Swerdlow, N.R.3
  • 21
    • 0347419233 scopus 로고    scopus 로고
    • Disruption of prepulse inhibition in mice lacking mglur1
    • Brody S.A., Conquet F., and Geyer M.A. Disruption of prepulse inhibition in mice lacking mglur1. Eur J Neurosci 18 (2003) 3361-3366
    • (2003) Eur J Neurosci , vol.18 , pp. 3361-3366
    • Brody, S.A.1    Conquet, F.2    Geyer, M.A.3
  • 22
    • 1642328941 scopus 로고    scopus 로고
    • Effect of antipsychotic treatment on the prepulse inhibition deficit of mglur5 knockout mice
    • Brody S.A., Conquet F., and Geyer M.A. Effect of antipsychotic treatment on the prepulse inhibition deficit of mglur5 knockout mice. Psychopharmacology (Berl) 172 (2004) 187-195
    • (2004) Psychopharmacology (Berl) , vol.172 , pp. 187-195
    • Brody, S.A.1    Conquet, F.2    Geyer, M.A.3
  • 23
    • 0842264953 scopus 로고    scopus 로고
    • Assessment of a prepulse inhibition deficit in a mutant mouse lacking mglu5 receptors
    • Brody S.A., Dulawa S.C., Conquet F., and Geyer M.A. Assessment of a prepulse inhibition deficit in a mutant mouse lacking mglu5 receptors. Mol Psychiatry 9 (2004) 35-41
    • (2004) Mol Psychiatry , vol.9 , pp. 35-41
    • Brody, S.A.1    Dulawa, S.C.2    Conquet, F.3    Geyer, M.A.4
  • 24
    • 3242752882 scopus 로고    scopus 로고
    • Interactions of the mglur5 gene with breeding and maternal factors on startle and prepulse inhibition in mice
    • Brody S.A., and Geyer M.A. Interactions of the mglur5 gene with breeding and maternal factors on startle and prepulse inhibition in mice. Neurotox Res 6 (2004) 79-90
    • (2004) Neurotox Res , vol.6 , pp. 79-90
    • Brody, S.A.1    Geyer, M.A.2
  • 25
    • 18144397834 scopus 로고    scopus 로고
    • A developmental influence of the N-methyl-d-aspartate receptor nr3a subunit on prepulse inhibition of startle
    • Brody S.A., Nakanishi N., Tu S., Lipton S.A., and Geyer M.A. A developmental influence of the N-methyl-d-aspartate receptor nr3a subunit on prepulse inhibition of startle. Biol Psychiatry 57 (2005) 1147-1152
    • (2005) Biol Psychiatry , vol.57 , pp. 1147-1152
    • Brody, S.A.1    Nakanishi, N.2    Tu, S.3    Lipton, S.A.4    Geyer, M.A.5
  • 26
    • 33847718214 scopus 로고    scopus 로고
    • The egf receptor family: spearheading a merger of signaling and therapeutics
    • Bublil E.M., and Yarden Y. The egf receptor family: spearheading a merger of signaling and therapeutics. Curr Opin Cell Biol 19 (2007) 124-134
    • (2007) Curr Opin Cell Biol , vol.19 , pp. 124-134
    • Bublil, E.M.1    Yarden, Y.2
  • 28
    • 0027490265 scopus 로고
    • Impaired startle prepulse inhibition and habituation in patients with schizotypal personality disorder
    • Cadenhead K.S., Geyer M.A., and Braff D.L. Impaired startle prepulse inhibition and habituation in patients with schizotypal personality disorder. Am J Psychiatry 150 (1993) 1862-1867
    • (1993) Am J Psychiatry , vol.150 , pp. 1862-1867
    • Cadenhead, K.S.1    Geyer, M.A.2    Braff, D.L.3
  • 29
    • 0033806859 scopus 로고    scopus 로고
    • Modulation of the startle response and startle laterality in relatives of schizophrenic patients and in subjects with schizotypal personality disorder: evidence of inhibitory deficits
    • Cadenhead K.S., Swerdlow N.R., Shafer K.M., Diaz M., and Braff D.L. Modulation of the startle response and startle laterality in relatives of schizophrenic patients and in subjects with schizotypal personality disorder: evidence of inhibitory deficits. Am J Psychiatry 157 (2000) 1660-1668
    • (2000) Am J Psychiatry , vol.157 , pp. 1660-1668
    • Cadenhead, K.S.1    Swerdlow, N.R.2    Shafer, K.M.3    Diaz, M.4    Braff, D.L.5
  • 30
    • 20844463251 scopus 로고    scopus 로고
    • Variation in disc1 affects hippocampal structure and function and increases risk for schizophrenia
    • Callicott J.H., Straub R.E., Pezawas L., Egan M.F., Mattay V.S., Hariri A.R., et al. Variation in disc1 affects hippocampal structure and function and increases risk for schizophrenia. Proc Natl Acad Sci USA 102 (2005) 8627-8632
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 8627-8632
    • Callicott, J.H.1    Straub, R.E.2    Pezawas, L.3    Egan, M.F.4    Mattay, V.S.5    Hariri, A.R.6
  • 31
    • 27744554247 scopus 로고    scopus 로고
    • Association of disc1/trax haplotypes with schizophrenia, reduced prefrontal gray matter, and impaired short- and long-term memory
    • Cannon T.D., Hennah W., van Erp T.G., Thompson P.M., Lonnqvist J., Huttunen M., et al. Association of disc1/trax haplotypes with schizophrenia, reduced prefrontal gray matter, and impaired short- and long-term memory. Arch Gen Psychiatry 62 (2005) 1205-1213
    • (2005) Arch Gen Psychiatry , vol.62 , pp. 1205-1213
    • Cannon, T.D.1    Hennah, W.2    van Erp, T.G.3    Thompson, P.M.4    Lonnqvist, J.5    Huttunen, M.6
  • 32
    • 0034060459 scopus 로고    scopus 로고
    • Twin studies of schizophrenia: from bow-and-arrow concordances to star wars mx and functional genomics
    • Cardno A.G., and Gottesman I.I. Twin studies of schizophrenia: from bow-and-arrow concordances to star wars mx and functional genomics. Am J Med Genet 97 (2000) 12-17
    • (2000) Am J Med Genet , vol.97 , pp. 12-17
    • Cardno, A.G.1    Gottesman, I.I.2
  • 33
    • 20944446077 scopus 로고    scopus 로고
    • Moderation of the effect of adolescent-onset cannabis use on adult psychosis by a functional polymorphism in the catechol-o-methyltransferase gene: longitudinal evidence of a gene x environment interaction
    • Caspi A., Moffitt T.E., Cannon M., McClay J., Murray R., Harrington H., et al. Moderation of the effect of adolescent-onset cannabis use on adult psychosis by a functional polymorphism in the catechol-o-methyltransferase gene: longitudinal evidence of a gene x environment interaction. Biol Psychiatry 57 (2005) 1117-1127
    • (2005) Biol Psychiatry , vol.57 , pp. 1117-1127
    • Caspi, A.1    Moffitt, T.E.2    Cannon, M.3    McClay, J.4    Murray, R.5    Harrington, H.6
  • 34
    • 8644282797 scopus 로고    scopus 로고
    • An orally bioavailable, functionally selective inverse agonist at the benzodiazepine site of gabaa α5 receptors with cognition enhancing properties
    • Chambers M.S., Atack J.R., Carling R.W., Collinson N., Cook S.M., Dawson G.R., et al. An orally bioavailable, functionally selective inverse agonist at the benzodiazepine site of gabaa α5 receptors with cognition enhancing properties. J Med Chem 47 (2004) 5829-5832
    • (2004) J Med Chem , vol.47 , pp. 5829-5832
    • Chambers, M.S.1    Atack, J.R.2    Carling, R.W.3    Collinson, N.4    Cook, S.M.5    Dawson, G.R.6
  • 35
    • 6344265879 scopus 로고    scopus 로고
    • Functional analysis of genetic variation in catechol-o-methyltransferase (comt): effects on mrna, protein, and enzyme activity in postmortem human brain
    • Chen J., Lipska B.K., Halim N., Ma Q.D., Matsumoto M., Melhem S., et al. Functional analysis of genetic variation in catechol-o-methyltransferase (comt): effects on mrna, protein, and enzyme activity in postmortem human brain. Am J Hum Genet 75 (2004) 807-821
    • (2004) Am J Hum Genet , vol.75 , pp. 807-821
    • Chen, J.1    Lipska, B.K.2    Halim, N.3    Ma, Q.D.4    Matsumoto, M.5    Melhem, S.6
  • 36
    • 49049113745 scopus 로고    scopus 로고
    • Type iii neuregulin-1 is required for normal sensorimotor gating, memory-related behaviors, and corticostriatal circuit components
    • Chen Y-JJ, Johnson M.A., Lieberman M.D., Goodchild R.E., Schobel S., Lewandowski N., et al. Type iii neuregulin-1 is required for normal sensorimotor gating, memory-related behaviors, and corticostriatal circuit components. J Neurosci 28 (2008) 6872-6883
    • (2008) J Neurosci , vol.28 , pp. 6872-6883
    • Chen Y-JJ1    Johnson, M.A.2    Lieberman, M.D.3    Goodchild, R.E.4    Schobel, S.5    Lewandowski, N.6
  • 37
    • 16244405559 scopus 로고    scopus 로고
    • Gaba transporter deficiency causes tremor, ataxia, nervousness, and increased gaba-induced tonic conductance in cerebellum
    • Chiu C.S., Brickley S., Jensen K., Southwell A., McKinney S., Cull-Candy S., et al. Gaba transporter deficiency causes tremor, ataxia, nervousness, and increased gaba-induced tonic conductance in cerebellum. J Neurosci 25 (2005) 3234-3245
    • (2005) J Neurosci , vol.25 , pp. 3234-3245
    • Chiu, C.S.1    Brickley, S.2    Jensen, K.3    Southwell, A.4    McKinney, S.5    Cull-Candy, S.6
  • 38
    • 0033964384 scopus 로고    scopus 로고
    • Homer-1c/vesl-1l modulates the cell surface targeting of metabotropic glutamate receptor type 1alpha: evidence for an anchoring function
    • Ciruela F., Soloviev M.M., Chan W.Y., and McIlhinney R.A. Homer-1c/vesl-1l modulates the cell surface targeting of metabotropic glutamate receptor type 1alpha: evidence for an anchoring function. Mol Cell Neurosci 15 (2000) 36-50
    • (2000) Mol Cell Neurosci , vol.15 , pp. 36-50
    • Ciruela, F.1    Soloviev, M.M.2    Chan, W.Y.3    McIlhinney, R.A.4
  • 41
    • 0017255979 scopus 로고
    • Dopamine receptor binding predicts clinical and pharmacological potencies of antischizophrenic drugs
    • Creese I., Burt D.R., and Snyder S.H. Dopamine receptor binding predicts clinical and pharmacological potencies of antischizophrenic drugs. Science 192 (1976) 481-483
    • (1976) Science , vol.192 , pp. 481-483
    • Creese, I.1    Burt, D.R.2    Snyder, S.H.3
  • 43
    • 38149016841 scopus 로고    scopus 로고
    • Haloperidol differentially modulates prepulse inhibition and p50 suppression in healthy humans stratified for low and high gating levels
    • Csomor P.A., Stadler R.R., Feldon J., Yee B.K., Geyer M.A., and Vollenweider F.X. Haloperidol differentially modulates prepulse inhibition and p50 suppression in healthy humans stratified for low and high gating levels. Neuropsychopharmacology 33 (2008) 497-512
    • (2008) Neuropsychopharmacology , vol.33 , pp. 497-512
    • Csomor, P.A.1    Stadler, R.R.2    Feldon, J.3    Yee, B.K.4    Geyer, M.A.5    Vollenweider, F.X.6
  • 45
    • 51749109072 scopus 로고    scopus 로고
    • Contributions of dopamine d1, d2, and d3 receptor subtypes to the disruptive effects of cocaine on prepulse inhibition in mice
    • Doherty J.M., Masten V.L., Powell S.B., Ralph R.J., Klamer D., Low M.J., et al. Contributions of dopamine d1, d2, and d3 receptor subtypes to the disruptive effects of cocaine on prepulse inhibition in mice. Neuropsychopharmacology 33 (2008) 2648-2656
    • (2008) Neuropsychopharmacology , vol.33 , pp. 2648-2656
    • Doherty, J.M.1    Masten, V.L.2    Powell, S.B.3    Ralph, R.J.4    Klamer, D.5    Low, M.J.6
  • 46
    • 50849106421 scopus 로고    scopus 로고
    • Behavioral profile of a heterozygous mutant mouse model for egf-like domain neuregulin 1
    • Duffy L., Cappas E., Scimone A., Schofield P.R., and Karl T. Behavioral profile of a heterozygous mutant mouse model for egf-like domain neuregulin 1. Behav Neurosci 122 (2008) 748-759
    • (2008) Behav Neurosci , vol.122 , pp. 748-759
    • Duffy, L.1    Cappas, E.2    Scimone, A.3    Schofield, P.R.4    Karl, T.5
  • 47
    • 0034052762 scopus 로고    scopus 로고
    • Knockout mice reveal opposite roles for serotonin 1a and 1b receptors in prepulse inhibition
    • Dulawa S.C., Gross C., Stark K.L., Hen R., and Geyer M.A. Knockout mice reveal opposite roles for serotonin 1a and 1b receptors in prepulse inhibition. Neuropsychopharmacology 22 (2000) 650-659
    • (2000) Neuropsychopharmacology , vol.22 , pp. 650-659
    • Dulawa, S.C.1    Gross, C.2    Stark, K.L.3    Hen, R.4    Geyer, M.A.5
  • 48
    • 30544437565 scopus 로고    scopus 로고
    • Effects of haloperidol, clozapine, and quetiapine on sensorimotor gating in a genetic model of reduced nmda receptor function
    • Duncan G.E., Moy S.S., Lieberman J.A., and Koller B.H. Effects of haloperidol, clozapine, and quetiapine on sensorimotor gating in a genetic model of reduced nmda receptor function. Psychopharmacology (Berl) 184 (2006) 190-200
    • (2006) Psychopharmacology (Berl) , vol.184 , pp. 190-200
    • Duncan, G.E.1    Moy, S.S.2    Lieberman, J.A.3    Koller, B.H.4
  • 49
    • 33846240932 scopus 로고    scopus 로고
    • Typical and atypical antipsychotic drug effects on locomotor hyperactivity and deficits in sensorimotor gating in a genetic model of nmda receptor hypofunction
    • Duncan G.E., Moy S.S., Lieberman J.A., and Koller B.H. Typical and atypical antipsychotic drug effects on locomotor hyperactivity and deficits in sensorimotor gating in a genetic model of nmda receptor hypofunction. Pharmacol Biochem Behav 85 (2006) 481-491
    • (2006) Pharmacol Biochem Behav , vol.85 , pp. 481-491
    • Duncan, G.E.1    Moy, S.S.2    Lieberman, J.A.3    Koller, B.H.4
  • 50
    • 0037126171 scopus 로고    scopus 로고
    • Nurr1-null heterozygous mice have reduced mesolimbic and mesocortical dopamine levels and increased stress-induced locomotor activity
    • Eells J.B., Lipska B.K., Yeung S.K., Misler J.A., and Nikodem V.M. Nurr1-null heterozygous mice have reduced mesolimbic and mesocortical dopamine levels and increased stress-induced locomotor activity. Behav Brain Res 136 (2002) 267-275
    • (2002) Behav Brain Res , vol.136 , pp. 267-275
    • Eells, J.B.1    Lipska, B.K.2    Yeung, S.K.3    Misler, J.A.4    Nikodem, V.M.5
  • 51
    • 33745242524 scopus 로고    scopus 로고
    • Early postnatal isolation reduces dopamine levels, elevates dopamine turnover and specifically disrupts prepulse inhibition in nurr1-null heterozygous mice
    • Eells J.B., Misler J.A., and Nikodem V.M. Early postnatal isolation reduces dopamine levels, elevates dopamine turnover and specifically disrupts prepulse inhibition in nurr1-null heterozygous mice. Neuroscience 140 (2006) 1117-1126
    • (2006) Neuroscience , vol.140 , pp. 1117-1126
    • Eells, J.B.1    Misler, J.A.2    Nikodem, V.M.3
  • 52
    • 33746870022 scopus 로고    scopus 로고
    • Performance deficit of alpha7 nicotinic receptor knockout mice in a delayed matching-to-place task suggests a mild impairment of working/episodic-like memory
    • Fernandes C., Hoyle E., Dempster E., Schalkwyk L.C., and Collier D.A. Performance deficit of alpha7 nicotinic receptor knockout mice in a delayed matching-to-place task suggests a mild impairment of working/episodic-like memory. Genes Brain Behav 5 (2006) 433-440
    • (2006) Genes Brain Behav , vol.5 , pp. 433-440
    • Fernandes, C.1    Hoyle, E.2    Dempster, E.3    Schalkwyk, L.C.4    Collier, D.A.5
  • 53
    • 0035029307 scopus 로고    scopus 로고
    • The scaffold protein, homer1b/c, regulates axon pathfinding in the central nervous system in vivo
    • Foa L., Rajan I., Haas K., Wu G.Y., Brakeman P., Worley P., et al. The scaffold protein, homer1b/c, regulates axon pathfinding in the central nervous system in vivo. Nat Neurosci 4 (2001) 499-506
    • (2001) Nat Neurosci , vol.4 , pp. 499-506
    • Foa, L.1    Rajan, I.2    Haas, K.3    Wu, G.Y.4    Brakeman, P.5    Worley, P.6
  • 54
    • 0032750752 scopus 로고    scopus 로고
    • Striatal dopamine metabolism in monoamine oxidase b-deficient mice: a brain dialysis study
    • Fornai F., Chen K., Giorgi F.S., Gesi M., Alessandri M.G., and Shih J.C. Striatal dopamine metabolism in monoamine oxidase b-deficient mice: a brain dialysis study. J Neurochem 73 (1999) 2434-2440
    • (1999) J Neurochem , vol.73 , pp. 2434-2440
    • Fornai, F.1    Chen, K.2    Giorgi, F.S.3    Gesi, M.4    Alessandri, M.G.5    Shih, J.C.6
  • 56
    • 0033104360 scopus 로고    scopus 로고
    • Alternative phenotypes for the complex genetics of schizophrenia
    • Freedman R., Adler L.E., and Leonard S. Alternative phenotypes for the complex genetics of schizophrenia. Biol Psychiatry 45 (1999) 551-558
    • (1999) Biol Psychiatry , vol.45 , pp. 551-558
    • Freedman, R.1    Adler, L.E.2    Leonard, S.3
  • 58
    • 0033555898 scopus 로고    scopus 로고
    • Role of serotonin in the paradoxical calming effect of psychostimulants on hyperactivity
    • Gainetdinov R.R., Wetsel W.C., Jones S.R., Levin E.D., Jaber M., and Caron M.G. Role of serotonin in the paradoxical calming effect of psychostimulants on hyperactivity. Science 283 (1999) 397-401
    • (1999) Science , vol.283 , pp. 397-401
    • Gainetdinov, R.R.1    Wetsel, W.C.2    Jones, S.R.3    Levin, E.D.4    Jaber, M.5    Caron, M.G.6
  • 59
    • 0038433234 scopus 로고    scopus 로고
    • Association of the g1947a comt (val(108/158)met) gene polymorphism with prefrontal p300 during information processing
    • Gallinat J., Bajbouj M., Sander T., Schlattmann P., Xu K., Ferro E.F., et al. Association of the g1947a comt (val(108/158)met) gene polymorphism with prefrontal p300 during information processing. Biol Psychiatry 54 (2003) 40-48
    • (2003) Biol Psychiatry , vol.54 , pp. 40-48
    • Gallinat, J.1    Bajbouj, M.2    Sander, T.3    Schlattmann, P.4    Xu, K.5    Ferro, E.F.6
  • 61
    • 36849091898 scopus 로고    scopus 로고
    • Hippocampal [alpha]5 subunit-containing gabaa receptors are involved in the development of the latent inhibition effect
    • Gerdjikov T.V., Rudolph U., Keist R., Möhler H., Feldon J., and Yee B.K. Hippocampal [alpha]5 subunit-containing gabaa receptors are involved in the development of the latent inhibition effect. Neurobiol Learn Mem 89 (2008) 87-94
    • (2008) Neurobiol Learn Mem , vol.89 , pp. 87-94
    • Gerdjikov, T.V.1    Rudolph, U.2    Keist, R.3    Möhler, H.4    Feldon, J.5    Yee, B.K.6
  • 62
    • 0034112445 scopus 로고    scopus 로고
    • Heregulin, but not erbb2 or erbb3, heterozygous mutant mice exhibit hyperactivity in multiple behavioral tasks
    • Gerlai R., Pisacane P., and Erickson S. Heregulin, but not erbb2 or erbb3, heterozygous mutant mice exhibit hyperactivity in multiple behavioral tasks. Behav Brain Res 109 (2000) 219-227
    • (2000) Behav Brain Res , vol.109 , pp. 219-227
    • Gerlai, R.1    Pisacane, P.2    Erickson, S.3
  • 63
    • 0345690103 scopus 로고    scopus 로고
    • Animal behavior models of the mechanisms underlying antipsychotic atypicality
    • Geyer M.A., and Ellenbroek B. Animal behavior models of the mechanisms underlying antipsychotic atypicality. Prog Neuropsychopharmacol Biol Psychiatry 27 (2003) 1071-1079
    • (2003) Prog Neuropsychopharmacol Biol Psychiatry , vol.27 , pp. 1071-1079
    • Geyer, M.A.1    Ellenbroek, B.2
  • 64
    • 0034917841 scopus 로고    scopus 로고
    • Pharmacological studies of prepulse inhibition models of sensorimotor gating deficits in schizophrenia: a decade in review
    • Geyer M.A., Krebs-Thomson K., Braff D.L., and Swerdlow N.R. Pharmacological studies of prepulse inhibition models of sensorimotor gating deficits in schizophrenia: a decade in review. Psychopharmacology (Berl) 156 (2001) 117-154
    • (2001) Psychopharmacology (Berl) , vol.156 , pp. 117-154
    • Geyer, M.A.1    Krebs-Thomson, K.2    Braff, D.L.3    Swerdlow, N.R.4
  • 65
    • 0010411289 scopus 로고    scopus 로고
    • The role of preclinical models in the development of psychotropic drugs
    • Davis K.L., Charney D., Coyle J.T., and Nemeroff C.B. (Eds), Lippincott, Williams & Wilkins
    • Geyer M.A., and Markou A. The role of preclinical models in the development of psychotropic drugs. In: Davis K.L., Charney D., Coyle J.T., and Nemeroff C.B. (Eds). Neuropsychopharmacology: the fifth generation of progress (2002), Lippincott, Williams & Wilkins 445-455
    • (2002) Neuropsychopharmacology: the fifth generation of progress , pp. 445-455
    • Geyer, M.A.1    Markou, A.2
  • 66
    • 0036929065 scopus 로고    scopus 로고
    • Mouse genetic models for prepulse inhibition: an early review
    • Geyer M.A., McIlwain K.L., and Paylor R. Mouse genetic models for prepulse inhibition: an early review. Mol Psychiatry 7 (2002) 1039-1053
    • (2002) Mol Psychiatry , vol.7 , pp. 1039-1053
    • Geyer, M.A.1    McIlwain, K.L.2    Paylor, R.3
  • 67
    • 2942599183 scopus 로고    scopus 로고
    • Animal models relevant to schizophrenia disorders
    • Charney D., Coyle J., Davis K., and Nemeroff C.B. (Eds), Lippincott, Williams & Wilkins
    • Geyer M.A., and Moghaddam B. Animal models relevant to schizophrenia disorders. In: Charney D., Coyle J., Davis K., and Nemeroff C.B. (Eds). Neuropsychopharmacology: the fifth generation of progress (2002), Lippincott, Williams & Wilkins 689-701
    • (2002) Neuropsychopharmacology: the fifth generation of progress , pp. 689-701
    • Geyer, M.A.1    Moghaddam, B.2
  • 68
    • 33645895263 scopus 로고    scopus 로고
    • The level of prepulse inhibition in healthy individuals may index cortical modulation of early information processing
    • Giakoumaki S.G., Bitsios P., and Frangou S. The level of prepulse inhibition in healthy individuals may index cortical modulation of early information processing. Brain Res 1078 (2006) 168-170
    • (2006) Brain Res , vol.1078 , pp. 168-170
    • Giakoumaki, S.G.1    Bitsios, P.2    Frangou, S.3
  • 69
    • 57349086379 scopus 로고    scopus 로고
    • Improvement of prepulse inhibition and executive function by the COMT inhibitor tolcapone depends on COMT val158met polymorphism
    • Giakoumaki S.G., Roussos P., and Bitsios P. Improvement of prepulse inhibition and executive function by the COMT inhibitor tolcapone depends on COMT val158met polymorphism. Neuropsychopharmacology 33 (2008) 3058-3068
    • (2008) Neuropsychopharmacology , vol.33 , pp. 3058-3068
    • Giakoumaki, S.G.1    Roussos, P.2    Bitsios, P.3
  • 70
    • 0030071106 scopus 로고    scopus 로고
    • Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter
    • Giros B., Jaber M., Jones S.R., Wightman R.M., and Caron M.G. Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter. Nature 379 (1996) 606-612
    • (1996) Nature , vol.379 , pp. 606-612
    • Giros, B.1    Jaber, M.2    Jones, S.R.3    Wightman, R.M.4    Caron, M.G.5
  • 71
    • 0033557737 scopus 로고    scopus 로고
    • A placebo-controlled crossover trial of d-cycloserine added to clozapine in patients with schizophrenia
    • Goff D.C., Henderson D.C., Evins A.E., and Amico E. A placebo-controlled crossover trial of d-cycloserine added to clozapine in patients with schizophrenia. Biol Psychiatry 45 (1999) 512-514
    • (1999) Biol Psychiatry , vol.45 , pp. 512-514
    • Goff, D.C.1    Henderson, D.C.2    Evins, A.E.3    Amico, E.4
  • 72
    • 0032902238 scopus 로고    scopus 로고
    • A placebo-controlled trial of d-cycloserine added to conventional neuroleptics in patients with schizophrenia
    • Goff D.C., Tsai G., Levitt J., Amico E., Manoach D., Schoenfeld D.A., et al. A placebo-controlled trial of d-cycloserine added to conventional neuroleptics in patients with schizophrenia. Arch Gen Psychiatry 56 (1999) 21-27
    • (1999) Arch Gen Psychiatry , vol.56 , pp. 21-27
    • Goff, D.C.1    Tsai, G.2    Levitt, J.3    Amico, E.4    Manoach, D.5    Schoenfeld, D.A.6
  • 73
    • 0029116094 scopus 로고
    • Dose-finding trial of d-cycloserine added to neuroleptics for negative symptoms in schizophrenia
    • Goff D.C., Tsai G., Manoach D.S., and Coyle J.T. Dose-finding trial of d-cycloserine added to neuroleptics for negative symptoms in schizophrenia. Am J Psychiatry 152 (1995) 1213-1215
    • (1995) Am J Psychiatry , vol.152 , pp. 1213-1215
    • Goff, D.C.1    Tsai, G.2    Manoach, D.S.3    Coyle, J.T.4
  • 74
    • 0032544012 scopus 로고    scopus 로고
    • Catechol-o-methyltransferase-deficient mice exhibit sexually dimorphic changes in catecholamine levels and behavior
    • Gogos J.A., Morgan M., Luine V., Santha M., Ogawa S., Pfaff D., et al. Catechol-o-methyltransferase-deficient mice exhibit sexually dimorphic changes in catecholamine levels and behavior. Proc Natl Acad Sci USA 95 (1998) 9991-9996
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 9991-9996
    • Gogos, J.A.1    Morgan, M.2    Luine, V.3    Santha, M.4    Ogawa, S.5    Pfaff, D.6
  • 75
    • 0032948179 scopus 로고    scopus 로고
    • The gene encoding proline dehydrogenase modulates sensorimotor gating in mice
    • Gogos J.A., Santha M., Takacs Z., Beck K.D., Luine V., Lucas L.R., et al. The gene encoding proline dehydrogenase modulates sensorimotor gating in mice. Nat Genet 21 (1999) 434-439
    • (1999) Nat Genet , vol.21 , pp. 434-439
    • Gogos, J.A.1    Santha, M.2    Takacs, Z.3    Beck, K.D.4    Luine, V.5    Lucas, L.R.6
  • 76
    • 33750469669 scopus 로고    scopus 로고
    • Association study of comt gene val158met polymorphism with auditory p300 and performance on neurocognitive tests in patients with schizophrenia and their relatives
    • Golimbet V., Gritsenko I., Alfimova M., Lebedeva I., Lezheiko T., Abramova L., et al. Association study of comt gene val158met polymorphism with auditory p300 and performance on neurocognitive tests in patients with schizophrenia and their relatives. World J Biol Psychiatry 7 (2006) 238-245
    • (2006) World J Biol Psychiatry , vol.7 , pp. 238-245
    • Golimbet, V.1    Gritsenko, I.2    Alfimova, M.3    Lebedeva, I.4    Lezheiko, T.5    Abramova, L.6
  • 77
    • 3042640878 scopus 로고    scopus 로고
    • Behavioral characteristics of a nervous system-specific erbb4 knock-out mouse
    • Golub M.S., Germann S.L., and Lloyd K.C. Behavioral characteristics of a nervous system-specific erbb4 knock-out mouse. Behav Brain Res 153 (2004) 159-170
    • (2004) Behav Brain Res , vol.153 , pp. 159-170
    • Golub, M.S.1    Germann, S.L.2    Lloyd, K.C.3
  • 78
    • 44149125060 scopus 로고    scopus 로고
    • Genes, brain development and psychiatric phenotypes in velo-cardio-facial syndrome
    • Gothelf D., Schaer M., and Eliez S. Genes, brain development and psychiatric phenotypes in velo-cardio-facial syndrome. Dev Disabil Res Rev 14 (2008) 59-68
    • (2008) Dev Disabil Res Rev , vol.14 , pp. 59-68
    • Gothelf, D.1    Schaer, M.2    Eliez, S.3
  • 80
    • 33644753148 scopus 로고    scopus 로고
    • Psychiatric endophenotypes and the development of valid animal models
    • Gould T.D., and Gottesman I.I. Psychiatric endophenotypes and the development of valid animal models. Genes Brain Behav 5 (2006) 113-119
    • (2006) Genes Brain Behav , vol.5 , pp. 113-119
    • Gould, T.D.1    Gottesman, I.I.2
  • 82
    • 61949104116 scopus 로고    scopus 로고
    • Clozapine reversess chizophrenia-related behaviours in the metabotropic glutamate receptor 5 knockout mouse: association with N-methyl-D-aspartic acid receptor up-regulation
    • Gray L., van den Buuse M., Scarr E., Dean B., and Hannan A.J. Clozapine reversess chizophrenia-related behaviours in the metabotropic glutamate receptor 5 knockout mouse: association with N-methyl-D-aspartic acid receptor up-regulation. Int J Neuropsychopharmacol 12 (2009) 45-60
    • (2009) Int J Neuropsychopharmacol , vol.12 , pp. 45-60
    • Gray, L.1    van den Buuse, M.2    Scarr, E.3    Dean, B.4    Hannan, A.J.5
  • 83
    • 57749193526 scopus 로고    scopus 로고
    • Perception measurement in clinical trials of schizophrenia: promising paradigms from cntrics
    • Green M.F., Butler P.D., Chen Y., Geyer M.A., Silverstein S., Wynn J.K., et al. Perception measurement in clinical trials of schizophrenia: promising paradigms from cntrics. Schizophr Bull 35 (2009) 163-181
    • (2009) Schizophr Bull , vol.35 , pp. 163-181
    • Green, M.F.1    Butler, P.D.2    Chen, Y.3    Geyer, M.A.4    Silverstein, S.5    Wynn, J.K.6
  • 84
    • 35948991435 scopus 로고    scopus 로고
    • Initial heritability analyses of endophenotypic measures for schizophrenia: the consortium on the genetics of schizophrenia
    • Greenwood T.A., Braff D.L., Light G.A., Cadenhead K.S., Calkins M.E., Dobie D.J., et al. Initial heritability analyses of endophenotypic measures for schizophrenia: the consortium on the genetics of schizophrenia. Arch Gen Psychiatry 64 (2007) 1242-1250
    • (2007) Arch Gen Psychiatry , vol.64 , pp. 1242-1250
    • Greenwood, T.A.1    Braff, D.L.2    Light, G.A.3    Cadenhead, K.S.4    Calkins, M.E.5    Dobie, D.J.6
  • 85
    • 33745684066 scopus 로고    scopus 로고
    • Neuregulin 1 and schizophrenia: genetics, gene expression, and neurobiology
    • Harrison P.J., and Law A.J. Neuregulin 1 and schizophrenia: genetics, gene expression, and neurobiology. Biol Psychiatry 60 (2006) 132-140
    • (2006) Biol Psychiatry , vol.60 , pp. 132-140
    • Harrison, P.J.1    Law, A.J.2
  • 86
    • 0037308528 scopus 로고    scopus 로고
    • Genes for schizophrenia? Recent findings and their pathophysiological implications
    • Harrison P.J., and Owen M.J. Genes for schizophrenia? Recent findings and their pathophysiological implications. Lancet 361 (2003) 417-419
    • (2003) Lancet , vol.361 , pp. 417-419
    • Harrison, P.J.1    Owen, M.J.2
  • 87
    • 12344327212 scopus 로고    scopus 로고
    • Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence
    • image 45
    • Harrison P.J., and Weinberger D.R. Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence. Mol Psychiatry 10 (2005) 40-68 image 45
    • (2005) Mol Psychiatry , vol.10 , pp. 40-68
    • Harrison, P.J.1    Weinberger, D.R.2
  • 88
    • 34347341560 scopus 로고    scopus 로고
    • Deficits in parvalbumin and calbindin immunoreactive cells in the hippocampus of isolation reared rats
    • Harte M.K., Powell S.B., Swerdlow N.R., Geyer M.A., and Reynolds G.P. Deficits in parvalbumin and calbindin immunoreactive cells in the hippocampus of isolation reared rats. J Neural Transm 114 (2007) 893-898
    • (2007) J Neural Transm , vol.114 , pp. 893-898
    • Harte, M.K.1    Powell, S.B.2    Swerdlow, N.R.3    Geyer, M.A.4    Reynolds, G.P.5
  • 89
    • 13244268304 scopus 로고    scopus 로고
    • Hippocampal [alpha]5 subunit-containing gabaa receptors modulate the expression of prepulse inhibition
    • Hauser J., Rudolph U., Keist R., Mohler H., Feldon J., and Yee B.K. Hippocampal [alpha]5 subunit-containing gabaa receptors modulate the expression of prepulse inhibition. Mol Psychiatry 10 (2004) 201-207
    • (2004) Mol Psychiatry , vol.10 , pp. 201-207
    • Hauser, J.1    Rudolph, U.2    Keist, R.3    Mohler, H.4    Feldon, J.5    Yee, B.K.6
  • 90
    • 4243654962 scopus 로고    scopus 로고
    • Sensorimotor gating deficits and hypofrontality in schizophrenia
    • Hazlett E.A., and Buchsbaum M.S. Sensorimotor gating deficits and hypofrontality in schizophrenia. Front Biosci 6 (2001) D1069-D1072
    • (2001) Front Biosci , vol.6
    • Hazlett, E.A.1    Buchsbaum, M.S.2
  • 91
    • 0031941351 scopus 로고    scopus 로고
    • Prefrontal cortex glucose metabolism and startle eyeblink modification abnormalities in unmedicated schizophrenia patients
    • Hazlett E.A., Buchsbaum M.S., Haznedar M.M., Singer M.B., Germans M.K., Schnur D.B., et al. Prefrontal cortex glucose metabolism and startle eyeblink modification abnormalities in unmedicated schizophrenia patients. Psychophysiology 35 (1998) 186-198
    • (1998) Psychophysiology , vol.35 , pp. 186-198
    • Hazlett, E.A.1    Buchsbaum, M.S.2    Haznedar, M.M.3    Singer, M.B.4    Germans, M.K.5    Schnur, D.B.6
  • 92
    • 4344614806 scopus 로고    scopus 로고
    • Prepulse inhibition deficits in gad65 knockout mice and the effect of antipsychotic treatment
    • Heldt S.A., Green A., and Ressler K.J. Prepulse inhibition deficits in gad65 knockout mice and the effect of antipsychotic treatment. Neuropsychopharmacology 29 (2004) 1610-1619
    • (2004) Neuropsychopharmacology , vol.29 , pp. 1610-1619
    • Heldt, S.A.1    Green, A.2    Ressler, K.J.3
  • 93
    • 32844455739 scopus 로고    scopus 로고
    • A haplotype within the disc1 gene is associated with visual memory functions in families with a high density of schizophrenia
    • Hennah W., Tuulio-Henriksson A., Paunio T., Ekelund J., Varilo T., Partonen T., et al. A haplotype within the disc1 gene is associated with visual memory functions in families with a high density of schizophrenia. Mol Psychiatry 10 (2005) 1097-1103
    • (2005) Mol Psychiatry , vol.10 , pp. 1097-1103
    • Hennah, W.1    Tuulio-Henriksson, A.2    Paunio, T.3    Ekelund, J.4    Varilo, T.5    Partonen, T.6
  • 94
    • 35448988145 scopus 로고    scopus 로고
    • Dominant-negative disc1 transgenic mice display schizophrenia-associated phenotypes detected by measures translatable to humans
    • Hikida T., Jaaro-Peled H., Seshadri S., Oishi K., Hookway C., Kong S., et al. Dominant-negative disc1 transgenic mice display schizophrenia-associated phenotypes detected by measures translatable to humans. Proc Natl Acad Sci USA 104 (2007) 14501-14506
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 14501-14506
    • Hikida, T.1    Jaaro-Peled, H.2    Seshadri, S.3    Oishi, K.4    Hookway, C.5    Kong, S.6
  • 95
    • 48749100440 scopus 로고    scopus 로고
    • Short-term selective breeding for high and low prepulse inhibition of the acoustic startle response; pharmacological characterization and qtl mapping in the selected lines
    • Hitzemann R., Malmanger B., Belknap J., Darakjian P., and McWeeney S. Short-term selective breeding for high and low prepulse inhibition of the acoustic startle response; pharmacological characterization and qtl mapping in the selected lines. Pharmacol Biochem Behav 90 (2008) 525-533
    • (2008) Pharmacol Biochem Behav , vol.90 , pp. 525-533
    • Hitzemann, R.1    Malmanger, B.2    Belknap, J.3    Darakjian, P.4    McWeeney, S.5
  • 96
    • 0018991381 scopus 로고
    • Reflex modification in the domain of startle. I. Some empirical findings and their implications for how the nervous system processes sensory input
    • Hoffman H.S., and Ison J.R. Reflex modification in the domain of startle. I. Some empirical findings and their implications for how the nervous system processes sensory input. Psychol Rev 87 (1980) 175-189
    • (1980) Psychol Rev , vol.87 , pp. 175-189
    • Hoffman, H.S.1    Ison, J.R.2
  • 98
    • 8744278883 scopus 로고    scopus 로고
    • Glutamate as a therapeutic target in psychiatric disorders
    • Javitt D.C. Glutamate as a therapeutic target in psychiatric disorders. Mol Psychiatry 9 (2004) 984-997
    • (2004) Mol Psychiatry , vol.9 , pp. 984-997
    • Javitt, D.C.1
  • 99
    • 0033558578 scopus 로고    scopus 로고
    • A.E. Bennett research award. Reversal of phencyclidine-induced effects by glycine and glycine transport inhibitors
    • Javitt D.C., Balla A., Sershen H., and Lajtha A. A.E. Bennett research award. Reversal of phencyclidine-induced effects by glycine and glycine transport inhibitors. Biol Psychiatry 45 (1999) 668-679
    • (1999) Biol Psychiatry , vol.45 , pp. 668-679
    • Javitt, D.C.1    Balla, A.2    Sershen, H.3    Lajtha, A.4
  • 100
    • 0034015991 scopus 로고    scopus 로고
    • Inhibition of striatal dopamine release by glycine and glycyldodecylamide
    • Javitt D.C., Sershen H., Hashim A., and Lajtha A. Inhibition of striatal dopamine release by glycine and glycyldodecylamide. Brain Res Bull 52 (2000) 213-216
    • (2000) Brain Res Bull , vol.52 , pp. 213-216
    • Javitt, D.C.1    Sershen, H.2    Hashim, A.3    Lajtha, A.4
  • 101
    • 0025952455 scopus 로고
    • Recent advances in the phencyclidine model of schizophrenia
    • Javitt D.C., and Zukin S.R. Recent advances in the phencyclidine model of schizophrenia. Am J Psychiatry 148 (1991) 1301-1308
    • (1991) Am J Psychiatry , vol.148 , pp. 1301-1308
    • Javitt, D.C.1    Zukin, S.R.2
  • 102
    • 0023091647 scopus 로고
    • Glycine potentiates the nmda response in cultured mouse brain neurons
    • Johnson J.W., and Ascher P. Glycine potentiates the nmda response in cultured mouse brain neurons. Nature 325 (1987) 529-531
    • (1987) Nature , vol.325 , pp. 529-531
    • Johnson, J.W.1    Ascher, P.2
  • 104
    • 0036849530 scopus 로고    scopus 로고
    • Provisional mapping of quantitative trait loci modulating the acoustic startle response and prepulse inhibition of acoustic startle
    • Joober R., Zarate J.M., Rouleau G.A., Skamene E., and Boksa P. Provisional mapping of quantitative trait loci modulating the acoustic startle response and prepulse inhibition of acoustic startle. Neuropsychopharmacology 27 (2002) 765-781
    • (2002) Neuropsychopharmacology , vol.27 , pp. 765-781
    • Joober, R.1    Zarate, J.M.2    Rouleau, G.A.3    Skamene, E.4    Boksa, P.5
  • 105
    • 33750634178 scopus 로고    scopus 로고
    • Altered expression of hippocampal dentate granule neuron genes in a mouse model of human 22q11 deletion syndrome
    • Jurata L.W., Gallagher P., Lemire A.L., Charles V., Brockman J.A., Illingworth E.L., et al. Altered expression of hippocampal dentate granule neuron genes in a mouse model of human 22q11 deletion syndrome. Schizophr Res 88 (2006) 251-259
    • (2006) Schizophr Res , vol.88 , pp. 251-259
    • Jurata, L.W.1    Gallagher, P.2    Lemire, A.L.3    Charles, V.4    Brockman, J.A.5    Illingworth, E.L.6
  • 106
    • 44249119348 scopus 로고    scopus 로고
    • Glycine and d: -serine, but not d: -cycloserine, attenuate prepulse inhibition deficits induced by nmda receptor antagonist mk-801
    • Kanahara N., Shimizu E., Ohgake S., Fujita Y., Kohno M., Hashimoto T., et al. Glycine and d: -serine, but not d: -cycloserine, attenuate prepulse inhibition deficits induced by nmda receptor antagonist mk-801. Psychopharmacology (Berl) 198 (2008) 363-374
    • (2008) Psychopharmacology (Berl) , vol.198 , pp. 363-374
    • Kanahara, N.1    Shimizu, E.2    Ohgake, S.3    Fujita, Y.4    Kohno, M.5    Hashimoto, T.6
  • 108
    • 34748906661 scopus 로고    scopus 로고
    • Altered motor activity, exploration and anxiety in heterozygous neuregulin 1 mutant mice: implications for understanding schizophrenia
    • Karl T., Duffy L., Scimone A., Harvey R.P., and Schofield P.R. Altered motor activity, exploration and anxiety in heterozygous neuregulin 1 mutant mice: implications for understanding schizophrenia. Genes Brain Behav 6 (2007) 677-687
    • (2007) Genes Brain Behav , vol.6 , pp. 677-687
    • Karl, T.1    Duffy, L.2    Scimone, A.3    Harvey, R.P.4    Schofield, P.R.5
  • 110
    • 33644871334 scopus 로고    scopus 로고
    • Disc1 is mutated in the 129s6/svev strain and modulates working memory in mice
    • Koike H., Arguello P.A., Kvajo M., Karayiorgou M., and Gogos J.A. Disc1 is mutated in the 129s6/svev strain and modulates working memory in mice. Proc Natl Acad Sci 103 (2006) 3693-3697
    • (2006) Proc Natl Acad Sci , vol.103 , pp. 3693-3697
    • Koike, H.1    Arguello, P.A.2    Kvajo, M.3    Karayiorgou, M.4    Gogos, J.A.5
  • 111
    • 0022369108 scopus 로고
    • Catecholamine metabolism: basic aspects and clinical significance
    • Kopin I.J. Catecholamine metabolism: basic aspects and clinical significance. Pharmacol Rev 37 (1985) 333-364
    • (1985) Pharmacol Rev , vol.37 , pp. 333-364
    • Kopin, I.J.1
  • 112
    • 33751103938 scopus 로고    scopus 로고
    • The roles of 5-ht1a and 5-ht2 receptors in the effects of 5-meo-dmt on locomotor activity and prepulse inhibition in rats
    • Krebs-Thomson K., Ruiz E.M., Masten V., Buell M., and Geyer M.A. The roles of 5-ht1a and 5-ht2 receptors in the effects of 5-meo-dmt on locomotor activity and prepulse inhibition in rats. Psychopharmacology (Berl) 189 (2006) 319-329
    • (2006) Psychopharmacology (Berl) , vol.189 , pp. 319-329
    • Krebs-Thomson, K.1    Ruiz, E.M.2    Masten, V.3    Buell, M.4    Geyer, M.A.5
  • 113
    • 0028323167 scopus 로고
    • Subanesthetic effects of the noncompetitive nmda antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses
    • Krystal J.H., Karper L.P., Seibyl J.P., Freeman G.K., Delaney R., Bremner J.D., et al. Subanesthetic effects of the noncompetitive nmda antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses. Arch Gen Psychiatry 51 (1994) 199-214
    • (1994) Arch Gen Psychiatry , vol.51 , pp. 199-214
    • Krystal, J.H.1    Karper, L.P.2    Seibyl, J.P.3    Freeman, G.K.4    Delaney, R.5    Bremner, J.D.6
  • 114
    • 50149119926 scopus 로고    scopus 로고
    • Cortical grey matter volume and sensorimotor gating in schizophrenia
    • Kumari V., Fannon D., Geyer M.A., Premkumar P., Antonova E., Simmons A., et al. Cortical grey matter volume and sensorimotor gating in schizophrenia. Cortex 44 (2008) 1206-1214
    • (2008) Cortex , vol.44 , pp. 1206-1214
    • Kumari, V.1    Fannon, D.2    Geyer, M.A.3    Premkumar, P.4    Antonova, E.5    Simmons, A.6
  • 115
    • 0242669399 scopus 로고    scopus 로고
    • Neural correlates of tactile prepulse inhibition: a functional mri study in normal and schizophrenic subjects
    • Kumari V., Gray J.A., Geyer M.A., Ffytche D., Soni W., Mitterschiffthaler M.T., et al. Neural correlates of tactile prepulse inhibition: a functional mri study in normal and schizophrenic subjects. Psychiatry Res 122 (2003) 99-113
    • (2003) Psychiatry Res , vol.122 , pp. 99-113
    • Kumari, V.1    Gray, J.A.2    Geyer, M.A.3    Ffytche, D.4    Soni, W.5    Mitterschiffthaler, M.T.6
  • 116
    • 44349132300 scopus 로고    scopus 로고
    • A mutation in mouse disc1 that models a schizophrenia risk allele leads to specific alterations in neuronal architecture and cognition
    • Kvajo M., McKellar H., Arguello P.A., Drew L.J., Moore H., MacDermott A.B., et al. A mutation in mouse disc1 that models a schizophrenia risk allele leads to specific alterations in neuronal architecture and cognition. Proc Natl Acad Sci USA 105 (2008) 7076-7081
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 7076-7081
    • Kvajo, M.1    McKellar, H.2    Arguello, P.A.3    Drew, L.J.4    Moore, H.5    MacDermott, A.B.6
  • 117
    • 0030004521 scopus 로고    scopus 로고
    • Human catechol-o-methyltransferase pharmacogenetics: description of a functional polymorphism and its potential application to neuropsychiatric disorders
    • Lachman H.M., Papolos D.F., Saito T., Yu Y.M., Szumlanski C.L., and Weinshilboum R.M. Human catechol-o-methyltransferase pharmacogenetics: description of a functional polymorphism and its potential application to neuropsychiatric disorders. Pharmacogenetics 6 (1996) 243-250
    • (1996) Pharmacogenetics , vol.6 , pp. 243-250
    • Lachman, H.M.1    Papolos, D.F.2    Saito, T.3    Yu, Y.M.4    Szumlanski, C.L.5    Weinshilboum, R.M.6
  • 118
    • 0344430085 scopus 로고    scopus 로고
    • Prepulse inhibition deficits of the startle reflex in neonatal ventral hippocampal-lesioned rats: reversal by glycine and a glycine transporter inhibitor
    • Le Pen G., Kew J., Alberati D., Borroni E., Heitz M.P., and Moreau J.L. Prepulse inhibition deficits of the startle reflex in neonatal ventral hippocampal-lesioned rats: reversal by glycine and a glycine transporter inhibitor. Biol Psychiatry 54 (2003) 1162-1170
    • (2003) Biol Psychiatry , vol.54 , pp. 1162-1170
    • Le Pen, G.1    Kew, J.2    Alberati, D.3    Borroni, E.4    Heitz, M.P.5    Moreau, J.L.6
  • 119
    • 0036897309 scopus 로고    scopus 로고
    • Association of promoter variants in the alpha7 nicotinic acetylcholine receptor subunit gene with an inhibitory deficit found in schizophrenia
    • Leonard S., Gault J., Hopkins J., Logel J., Vianzon R., Short M., et al. Association of promoter variants in the alpha7 nicotinic acetylcholine receptor subunit gene with an inhibitory deficit found in schizophrenia. Arch Gen Psychiatry 59 (2002) 1085-1096
    • (2002) Arch Gen Psychiatry , vol.59 , pp. 1085-1096
    • Leonard, S.1    Gault, J.2    Hopkins, J.3    Logel, J.4    Vianzon, R.5    Short, M.6
  • 120
    • 3142726152 scopus 로고    scopus 로고
    • Selective alterations in prefrontal cortical gaba neurotransmission in schizophrenia: a novel target for the treatment of working memory dysfunction
    • Lewis D.A., Volk D.W., and Hashimoto T. Selective alterations in prefrontal cortical gaba neurotransmission in schizophrenia: a novel target for the treatment of working memory dysfunction. Psychopharmacology (Berl) 174 (2004) 143-150
    • (2004) Psychopharmacology (Berl) , vol.174 , pp. 143-150
    • Lewis, D.A.1    Volk, D.W.2    Hashimoto, T.3
  • 121
    • 36749042144 scopus 로고    scopus 로고
    • Specific developmental disruption of disrupted-in-schizophrenia-1 function results in schizophrenia-related phenotypes in mice
    • Li W., Zhou Y., Jentsch J.D., Brown R.A., Tian X., Ehninger D., et al. Specific developmental disruption of disrupted-in-schizophrenia-1 function results in schizophrenia-related phenotypes in mice. Proc Natl Acad Sci USA 104 (2007) 18280-18285
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 18280-18285
    • Li, W.1    Zhou, Y.2    Jentsch, J.D.3    Brown, R.A.4    Tian, X.5    Ehninger, D.6
  • 122
    • 17744372866 scopus 로고    scopus 로고
    • Modulators of the glycine site on nmda receptors, d-serine and alx 5407, display similar beneficial effects to clozapine in mouse models of schizophrenia
    • Lipina T., Labrie V., Weiner I., and Roder J. Modulators of the glycine site on nmda receptors, d-serine and alx 5407, display similar beneficial effects to clozapine in mouse models of schizophrenia. Psychopharmacology (Berl) 179 (2005) 54-67
    • (2005) Psychopharmacology (Berl) , vol.179 , pp. 54-67
    • Lipina, T.1    Labrie, V.2    Weiner, I.3    Roder, J.4
  • 123
    • 33947230697 scopus 로고    scopus 로고
    • The ampakine cx546 restores the prepulse inhibition and latent inhibition deficits in mglur5-deficient mice
    • Lipina T., Weiss K., and Roder J. The ampakine cx546 restores the prepulse inhibition and latent inhibition deficits in mglur5-deficient mice. Neuropsychopharmacology 32 (2007) 745-756
    • (2007) Neuropsychopharmacology , vol.32 , pp. 745-756
    • Lipina, T.1    Weiss, K.2    Roder, J.3
  • 125
    • 30744478436 scopus 로고    scopus 로고
    • Distinct roles for different homer1 isoforms in behaviors and associated prefrontal cortex function
    • Lominac K.D., Oleson E.B., Pava M., Klugmann M., Schwarz M.K., Seeburg P.H., et al. Distinct roles for different homer1 isoforms in behaviors and associated prefrontal cortex function. J Neurosci 25 (2005) 11586-11594
    • (2005) J Neurosci , vol.25 , pp. 11586-11594
    • Lominac, K.D.1    Oleson, E.B.2    Pava, M.3    Klugmann, M.4    Schwarz, M.K.5    Seeburg, P.H.6
  • 126
    • 34247553861 scopus 로고    scopus 로고
    • What is a schizophrenic mouse?
    • Low N.C., and Hardy J. What is a schizophrenic mouse?. Neuron 54 (2007) 348-349
    • (2007) Neuron , vol.54 , pp. 348-349
    • Low, N.C.1    Hardy, J.2
  • 127
    • 34548478801 scopus 로고    scopus 로고
    • Effect of catechol o-methyltransferase val(158)met polymorphism on the p50 gating endophenotype in schizophrenia
    • Lu B.Y., Martin K.E., Edgar J.C., Smith A.K., Lewis S.F., Escamilla M.A., et al. Effect of catechol o-methyltransferase val(158)met polymorphism on the p50 gating endophenotype in schizophrenia. Biol Psychiatry 62 (2007) 822-825
    • (2007) Biol Psychiatry , vol.62 , pp. 822-825
    • Lu, B.Y.1    Martin, K.E.2    Edgar, J.C.3    Smith, A.K.4    Lewis, S.F.5    Escamilla, M.A.6
  • 128
    • 0037770351 scopus 로고    scopus 로고
    • Deficits in prepulse inhibition and habituation in never-medicated, first-episode schizophrenia
    • Ludewig K., Geyer M.A., and Vollenweider F.X. Deficits in prepulse inhibition and habituation in never-medicated, first-episode schizophrenia. Biol Psychiatry 54 (2003) 121-128
    • (2003) Biol Psychiatry , vol.54 , pp. 121-128
    • Ludewig, K.1    Geyer, M.A.2    Vollenweider, F.X.3
  • 130
    • 0036838560 scopus 로고    scopus 로고
    • Effects of antipsychotics on prepulse inhibition of the startle response in drug-naive schizophrenic patients
    • Mackeprang T., Kristiansen K.T., and Glenthoj B.Y. Effects of antipsychotics on prepulse inhibition of the startle response in drug-naive schizophrenic patients. Biol Psychiatry 52 (2002) 863-873
    • (2002) Biol Psychiatry , vol.52 , pp. 863-873
    • Mackeprang, T.1    Kristiansen, K.T.2    Glenthoj, B.Y.3
  • 131
    • 33846873634 scopus 로고    scopus 로고
    • Role of disc1 in neural development and schizophrenia
    • Mackie S., Millar J.K., and Porteous D.J. Role of disc1 in neural development and schizophrenia. Curr Opin Neurobiol 17 (2007) 95-102
    • (2007) Curr Opin Neurobiol , vol.17 , pp. 95-102
    • Mackie, S.1    Millar, J.K.2    Porteous, D.J.3
  • 132
    • 0030861444 scopus 로고    scopus 로고
    • Clozapine blunts N-methyl-d-aspartate antagonist-induced psychosis: a study with ketamine
    • Malhotra A.K., Adler C.M., Kennison S.D., Elman I., Pickar D., and Breier A. Clozapine blunts N-methyl-d-aspartate antagonist-induced psychosis: a study with ketamine. Biol Psychiatry 42 (1997) 664-668
    • (1997) Biol Psychiatry , vol.42 , pp. 664-668
    • Malhotra, A.K.1    Adler, C.M.2    Kennison, S.D.3    Elman, I.4    Pickar, D.5    Breier, A.6
  • 133
    • 0030749913 scopus 로고    scopus 로고
    • Ketamine-induced exacerbation of psychotic symptoms and cognitive impairment in neuroleptic-free schizophrenics
    • Malhotra A.K., Pinals D.A., Adler C.M., Elman I., Clifton A., Pickar D., et al. Ketamine-induced exacerbation of psychotic symptoms and cognitive impairment in neuroleptic-free schizophrenics. Neuropsychopharmacology 17 (1997) 141-150
    • (1997) Neuropsychopharmacology , vol.17 , pp. 141-150
    • Malhotra, A.K.1    Pinals, D.A.2    Adler, C.M.3    Elman, I.4    Clifton, A.5    Pickar, D.6
  • 134
    • 3142761435 scopus 로고    scopus 로고
    • Alpha-7 nicotinic receptor agonists: potential new candidates for the treatment of schizophrenia
    • Martin L.F., Kem W.R., and Freedman R. Alpha-7 nicotinic receptor agonists: potential new candidates for the treatment of schizophrenia. Psychopharmacology (Berl) 174 (2004) 54-64
    • (2004) Psychopharmacology (Berl) , vol.174 , pp. 54-64
    • Martin, L.F.1    Kem, W.R.2    Freedman, R.3
  • 136
    • 0028179069 scopus 로고
    • N-methyl-d-aspartic acid receptor structure and function
    • McBain C.J., and Mayer M.L. N-methyl-d-aspartic acid receptor structure and function. Physiol Rev 74 (1994) 723-760
    • (1994) Physiol Rev , vol.74 , pp. 723-760
    • McBain, C.J.1    Mayer, M.L.2
  • 137
    • 45549107762 scopus 로고    scopus 로고
    • Phospholipase c-beta1 knockout mice exhibit endophenotypes modeling schizophrenia which are rescued by environmental enrichment and clozapine administration
    • McOmish C.E., Burrows E., Howard M., Scarr E., Kim D., Shin H.S., et al. Phospholipase c-beta1 knockout mice exhibit endophenotypes modeling schizophrenia which are rescued by environmental enrichment and clozapine administration. Mol Psychiatry 13 (2008) 661-672
    • (2008) Mol Psychiatry , vol.13 , pp. 661-672
    • McOmish, C.E.1    Burrows, E.2    Howard, M.3    Scarr, E.4    Kim, D.5    Shin, H.S.6
  • 138
    • 43949084738 scopus 로고    scopus 로고
    • Neuregulin 1 in neural development, synaptic plasticity and schizophrenia
    • Mei L., and Xiong W.C. Neuregulin 1 in neural development, synaptic plasticity and schizophrenia. Nat Rev Neurosci 9 (2008) 437-452
    • (2008) Nat Rev Neurosci , vol.9 , pp. 437-452
    • Mei, L.1    Xiong, W.C.2
  • 139
    • 13244258251 scopus 로고    scopus 로고
    • Prepulse inhibition of the acoustically evoked startle reflex in patients with an acute schizophrenic psychosis-a longitudinal study
    • Meincke U., Morth D., Voss T., Thelen B., Geyer M.A., and Gouzoulis-Mayfrank E. Prepulse inhibition of the acoustically evoked startle reflex in patients with an acute schizophrenic psychosis-a longitudinal study. Eur Arch Psychiatry Clin Neurosci 254 (2004) 415-421
    • (2004) Eur Arch Psychiatry Clin Neurosci , vol.254 , pp. 415-421
    • Meincke, U.1    Morth, D.2    Voss, T.3    Thelen, B.4    Geyer, M.A.5    Gouzoulis-Mayfrank, E.6
  • 140
    • 23244437953 scopus 로고    scopus 로고
    • Towards an immuno-precipitated neurodevelopmental animal model of schizophrenia
    • Meyer U., Feldon J., Schedlowski M., and Yee B.K. Towards an immuno-precipitated neurodevelopmental animal model of schizophrenia. Neurosci Biobehav Rev 29 (2005) 913-947
    • (2005) Neurosci Biobehav Rev , vol.29 , pp. 913-947
    • Meyer, U.1    Feldon, J.2    Schedlowski, M.3    Yee, B.K.4
  • 141
    • 34250183473 scopus 로고    scopus 로고
    • A receptors
    • A receptors. J Neurochem 102 (2007) 1-12
    • (2007) J Neurochem , vol.102 , pp. 1-12
    • Möhler, H.1
  • 142
    • 33646817432 scopus 로고    scopus 로고
    • Amphetamine-induced disruption of prepulse inhibition in mice with reduced nmda receptor function
    • Moy S.S., Perez A., Koller B.H., and Duncan G.E. Amphetamine-induced disruption of prepulse inhibition in mice with reduced nmda receptor function. Brain Res 1089 (2006) 186-194
    • (2006) Brain Res , vol.1089 , pp. 186-194
    • Moy, S.S.1    Perez, A.2    Koller, B.H.3    Duncan, G.E.4
  • 143
    • 33845329226 scopus 로고    scopus 로고
    • Susceptibility genes for schizophrenia: characterisation of mutant mouse models at the level of phenotypic behaviour
    • O'Tuathaigh C.M., Babovic D., O'Meara G., Clifford J.J., Croke D.T., and Waddington J.L. Susceptibility genes for schizophrenia: characterisation of mutant mouse models at the level of phenotypic behaviour. Neurosci Biobehav Rev 31 (2007) 60-78
    • (2007) Neurosci Biobehav Rev , vol.31 , pp. 60-78
    • O'Tuathaigh, C.M.1    Babovic, D.2    O'Meara, G.3    Clifford, J.J.4    Croke, D.T.5    Waddington, J.L.6
  • 144
    • 34249888202 scopus 로고    scopus 로고
    • Phenotypic characterization of spatial cognition and social behavior in mice with 'knockout' of the schizophrenia risk gene neuregulin 1
    • O'Tuathaigh C.M., Babovic D., O'Sullivan G.J., Clifford J.J., Tighe O., Croke D.T., et al. Phenotypic characterization of spatial cognition and social behavior in mice with 'knockout' of the schizophrenia risk gene neuregulin 1. Neuroscience 147 (2007) 18-27
    • (2007) Neuroscience , vol.147 , pp. 18-27
    • O'Tuathaigh, C.M.1    Babovic, D.2    O'Sullivan, G.J.3    Clifford, J.J.4    Tighe, O.5    Croke, D.T.6
  • 146
    • 0036839191 scopus 로고    scopus 로고
    • Modulating sensory gating in healthy volunteers: the effects of ketamine and haloperidol
    • Oranje B., Gispen-de Wied C.C., Verbaten M.N., and Kahn R.S. Modulating sensory gating in healthy volunteers: the effects of ketamine and haloperidol. Biol Psychiatry 52 (2002) 887-895
    • (2002) Biol Psychiatry , vol.52 , pp. 887-895
    • Oranje, B.1    Gispen-de Wied, C.C.2    Verbaten, M.N.3    Kahn, R.S.4
  • 147
    • 52049116298 scopus 로고    scopus 로고
    • Genetic dissection of the role of catechol-o-methyltransferase in cognition and stress reactivity in mice
    • Papaleo F., Crawley J.N., Song J., Lipska B.K., Pickel J., Weinberger D.R., et al. Genetic dissection of the role of catechol-o-methyltransferase in cognition and stress reactivity in mice. J Neurosci 28 (2008) 8709-8723
    • (2008) J Neurosci , vol.28 , pp. 8709-8723
    • Papaleo, F.1    Crawley, J.N.2    Song, J.3    Lipska, B.K.4    Pickel, J.5    Weinberger, D.R.6
  • 148
    • 27644478443 scopus 로고    scopus 로고
    • Transcriptional and behavioral interaction between 22q11.2 orthologs modulates schizophrenia-related phenotypes in mice
    • Paterlini M., Zakharenko S.S., Lai W.S., Qin J., Zhang H., Mukai J., et al. Transcriptional and behavioral interaction between 22q11.2 orthologs modulates schizophrenia-related phenotypes in mice. Nat Neurosci 8 (2005) 1586-1594
    • (2005) Nat Neurosci , vol.8 , pp. 1586-1594
    • Paterlini, M.1    Zakharenko, S.S.2    Lai, W.S.3    Qin, J.4    Zhang, H.5    Mukai, J.6
  • 149
    • 0030750286 scopus 로고    scopus 로고
    • Inbred strain differences in prepulse inhibition of the mouse startle response
    • Paylor R., and Crawley J.N. Inbred strain differences in prepulse inhibition of the mouse startle response. Psychopharmacology 132 (1997) 169-180
    • (1997) Psychopharmacology , vol.132 , pp. 169-180
    • Paylor, R.1    Crawley, J.N.2
  • 150
    • 0032216670 scopus 로고    scopus 로고
    • Alpha7 nicotinic receptor subunits are not necessary for hippocampal-dependent learning or sensorimotor gating: a behavioral characterization of acra7-deficient mice
    • Paylor R., Nguyen M., Crawley J.N., Patrick J., Beaudet A., and Orr-Urtreger A. Alpha7 nicotinic receptor subunits are not necessary for hippocampal-dependent learning or sensorimotor gating: a behavioral characterization of acra7-deficient mice. Learn Mem (Cold Spring Harbor, N.Y.) 5 (1998) 302-316
    • (1998) Learn Mem (Cold Spring Harbor, N.Y.) , vol.5 , pp. 302-316
    • Paylor, R.1    Nguyen, M.2    Crawley, J.N.3    Patrick, J.4    Beaudet, A.5    Orr-Urtreger, A.6
  • 151
    • 0028265092 scopus 로고
    • Information-processing deficits and thought disorder in schizophrenia
    • Perry W., and Braff D.L. Information-processing deficits and thought disorder in schizophrenia. Am J Psychiatry 151 (1994) 363-367
    • (1994) Am J Psychiatry , vol.151 , pp. 363-367
    • Perry, W.1    Braff, D.L.2
  • 152
    • 0033048833 scopus 로고    scopus 로고
    • Sensorimotor gating and thought disturbance measured in close temporal proximity in schizophrenic patients
    • Perry W., Geyer M.A., and Braff D.L. Sensorimotor gating and thought disturbance measured in close temporal proximity in schizophrenic patients. Arch Gen Psychiatry 56 (1999) 277-281
    • (1999) Arch Gen Psychiatry , vol.56 , pp. 277-281
    • Perry, W.1    Geyer, M.A.2    Braff, D.L.3
  • 153
    • 0035884094 scopus 로고    scopus 로고
    • Sensorimotor gating deficits in bipolar disorder patients with acute psychotic mania
    • Perry W., Minassian A., Feifel D., and Braff D.L. Sensorimotor gating deficits in bipolar disorder patients with acute psychotic mania. Biol Psychiatry 50 (2001) 418-424
    • (2001) Biol Psychiatry , vol.50 , pp. 418-424
    • Perry, W.1    Minassian, A.2    Feifel, D.3    Braff, D.L.4
  • 155
    • 38349114264 scopus 로고    scopus 로고
    • Inducible expression of mutant human disc1 in mice is associated with brain and behavioral abnormalities reminiscent of schizophrenia
    • Pletnikov M.V., Ayhan Y., Nikolskaia O., Xu Y., Ovanesov M.V., Huang H., et al. Inducible expression of mutant human disc1 in mice is associated with brain and behavioral abnormalities reminiscent of schizophrenia. Mol Psychiatry 13 (2007) 173-186
    • (2007) Mol Psychiatry , vol.13 , pp. 173-186
    • Pletnikov, M.V.1    Ayhan, Y.2    Nikolskaia, O.3    Xu, Y.4    Ovanesov, M.V.5    Huang, H.6
  • 156
    • 33745048992 scopus 로고    scopus 로고
    • Disrupted in schizophrenia 1: building brains and memories
    • Porteous D.J., and Millar J.K. Disrupted in schizophrenia 1: building brains and memories. Trends Mol Med 12 (2006) 255-261
    • (2006) Trends Mol Med , vol.12 , pp. 255-261
    • Porteous, D.J.1    Millar, J.K.2
  • 157
    • 33745712343 scopus 로고    scopus 로고
    • The genetics and biology of disc1-an emerging role in psychosis and cognition
    • Porteous D.J., Thomson P., Brandon N.J., and Millar J.K. The genetics and biology of disc1-an emerging role in psychosis and cognition. Biol Psychiatry 60 (2006) 123-131
    • (2006) Biol Psychiatry , vol.60 , pp. 123-131
    • Porteous, D.J.1    Thomson, P.2    Brandon, N.J.3    Millar, J.K.4
  • 158
    • 32844466873 scopus 로고    scopus 로고
    • A behavioural and functional neuroimaging investigation into the effects of nicotine on sensorimotor gating in healthy subjects and persons with schizophrenia
    • Postma P., Gray J.A., Sharma T., Geyer M., Mehrotra R., Das M., et al. A behavioural and functional neuroimaging investigation into the effects of nicotine on sensorimotor gating in healthy subjects and persons with schizophrenia. Psychopharmacology (Berl) 184 (2006) 589-599
    • (2006) Psychopharmacology (Berl) , vol.184 , pp. 589-599
    • Postma, P.1    Gray, J.A.2    Sharma, T.3    Geyer, M.4    Mehrotra, R.5    Das, M.6
  • 159
    • 69249217027 scopus 로고    scopus 로고
    • Powell SB, Risbrough VB, Lehmann-Masten V, Krebs-Thomson K, Hen R, Gingrich JA, Geyer MA. The indoleamine hallucinogens, psilocin and 5meodmt, increase prepulse inhibition in mice: role of 5-ht1a and 5-ht2a receptors. Society for Neuroscience, New Orleans, LA, 2003 Abstract Viewer/Itinerary Planner, 2003, Program No. 315.7.
    • Powell SB, Risbrough VB, Lehmann-Masten V, Krebs-Thomson K, Hen R, Gingrich JA, Geyer MA. The indoleamine hallucinogens, psilocin and 5meodmt, increase prepulse inhibition in mice: role of 5-ht1a and 5-ht2a receptors. Society for Neuroscience, New Orleans, LA, 2003 Abstract Viewer/Itinerary Planner, 2003, Program No. 315.7.
  • 160
    • 58149335563 scopus 로고    scopus 로고
    • Atypical antipsychotics clozapine and quetiapine attenuate prepulse inhibition deficits in dopamine transporter knockout mice
    • Powell S.B., Young J.W., Ong J.C., Caron M.G., and Geyer M.A. Atypical antipsychotics clozapine and quetiapine attenuate prepulse inhibition deficits in dopamine transporter knockout mice. Behav Pharmacol 19 (2008) 562-565
    • (2008) Behav Pharmacol , vol.19 , pp. 562-565
    • Powell, S.B.1    Young, J.W.2    Ong, J.C.3    Caron, M.G.4    Geyer, M.A.5
  • 161
    • 55449110753 scopus 로고    scopus 로고
    • Sensorimotor gating of schizophrenia patients depends on catechol o-methyltransferase val158met polymorphism
    • sbn088
    • Quednow B.B., Wagner M., Mossner R., Maier W., and Kuhn K.-U. Sensorimotor gating of schizophrenia patients depends on catechol o-methyltransferase val158met polymorphism. Schizophr Bull (2008) sbn088
    • (2008) Schizophr Bull
    • Quednow, B.B.1    Wagner, M.2    Mossner, R.3    Maier, W.4    Kuhn, K.-U.5
  • 162
    • 0037208934 scopus 로고    scopus 로고
    • Dopamine d1 rather than d2 receptor agonists disrupt prepulse inhibition of startle in mice
    • Ralph-Williams R.J., Lehmann-Masten V., and Geyer M.A. Dopamine d1 rather than d2 receptor agonists disrupt prepulse inhibition of startle in mice. Neuropsychopharmacology 28 (2003) 108-118
    • (2003) Neuropsychopharmacology , vol.28 , pp. 108-118
    • Ralph-Williams, R.J.1    Lehmann-Masten, V.2    Geyer, M.A.3
  • 163
    • 13244295493 scopus 로고    scopus 로고
    • Dopamine d1 and d2 agonist effects on prepulse inhibition and locomotion: comparison of Sprague-Dawley rats to swiss-webster, 129x1/svj, c57bl/6j, and dba/2j mice
    • Ralph R.J., and Caine S.B. Dopamine d1 and d2 agonist effects on prepulse inhibition and locomotion: comparison of Sprague-Dawley rats to swiss-webster, 129x1/svj, c57bl/6j, and dba/2j mice. J Pharmacol Exp Ther 312 (2005) 733-741
    • (2005) J Pharmacol Exp Ther , vol.312 , pp. 733-741
    • Ralph, R.J.1    Caine, S.B.2
  • 164
    • 0035143189 scopus 로고    scopus 로고
    • Prepulse inhibition deficits and perseverative motor patterns in dopamine transporter knock-out mice: differential effects of d1 and d2 receptor antagonists
    • Ralph R.J., Paulus M.P., Fumagalli F., Caron M.G., and Geyer M.A. Prepulse inhibition deficits and perseverative motor patterns in dopamine transporter knock-out mice: differential effects of d1 and d2 receptor antagonists. J Neurosci 21 (2001) 305-313
    • (2001) J Neurosci , vol.21 , pp. 305-313
    • Ralph, R.J.1    Paulus, M.P.2    Fumagalli, F.3    Caron, M.G.4    Geyer, M.A.5
  • 165
    • 0033137356 scopus 로고    scopus 로고
    • The dopamine d2, but not d3 or d4, receptor subtype is essential for the disruption of prepulse inhibition produced by amphetamine in mice
    • Ralph R.J., Varty G.B., Kelly M.A., Wang Y.M., Caron M.G., Rubinstein M., et al. The dopamine d2, but not d3 or d4, receptor subtype is essential for the disruption of prepulse inhibition produced by amphetamine in mice. J Neurosci 19 (1999) 4627-4633
    • (1999) J Neurosci , vol.19 , pp. 4627-4633
    • Ralph, R.J.1    Varty, G.B.2    Kelly, M.A.3    Wang, Y.M.4    Caron, M.G.5    Rubinstein, M.6
  • 166
    • 3242809106 scopus 로고    scopus 로고
    • Calcium binding protein markers of gaba deficits in schizophrenia-postmortem studies and animal models
    • Reynolds G.P., Abdul-Monim Z., Neill J.C., and Zhang Z.J. Calcium binding protein markers of gaba deficits in schizophrenia-postmortem studies and animal models. Neurotox Res 6 (2004) 57-61
    • (2004) Neurotox Res , vol.6 , pp. 57-61
    • Reynolds, G.P.1    Abdul-Monim, Z.2    Neill, J.C.3    Zhang, Z.J.4
  • 167
    • 0025208187 scopus 로고
    • Deficit and hemispheric asymmetry of gaba uptake sites in the hippocampus in schizophrenia
    • Reynolds G.P., Czudek C., and Andrews H.B. Deficit and hemispheric asymmetry of gaba uptake sites in the hippocampus in schizophrenia. Biol Psychiatry 27 (1990) 1038-1044
    • (1990) Biol Psychiatry , vol.27 , pp. 1038-1044
    • Reynolds, G.P.1    Czudek, C.2    Andrews, H.B.3
  • 168
    • 14944350075 scopus 로고    scopus 로고
    • Neuregulin-1 immunoglobulin-like domain mutant mice: clozapine sensitivity and impaired latent inhibition
    • Rimer M., Barrett D.W., Maldonado M.A., Vock V.M., and Gonzalez-Lima F. Neuregulin-1 immunoglobulin-like domain mutant mice: clozapine sensitivity and impaired latent inhibition. Neuroreport 16 (2005) 271-275
    • (2005) Neuroreport , vol.16 , pp. 271-275
    • Rimer, M.1    Barrett, D.W.2    Maldonado, M.A.3    Vock, V.M.4    Gonzalez-Lima, F.5
  • 169
    • 4644271084 scopus 로고    scopus 로고
    • Magic shotguns versus magic bullets: selectively non-selective drugs for mood disorders and schizophrenia
    • Roth B.L., Sheffler D.J., and Kroeze W.K. Magic shotguns versus magic bullets: selectively non-selective drugs for mood disorders and schizophrenia. Nat Rev Drug Discov 3 (2004) 353-359
    • (2004) Nat Rev Drug Discov , vol.3 , pp. 353-359
    • Roth, B.L.1    Sheffler, D.J.2    Kroeze, W.K.3
  • 170
    • 46849120124 scopus 로고    scopus 로고
    • Prepulse inhibition of the startle reflex depends on the catechol o-methyltransferase val158met gene polymorphism
    • Roussos P., Giakoumaki S.G., Rogdaki M., Pavlakis S., Frangou S., and Bitsios P. Prepulse inhibition of the startle reflex depends on the catechol o-methyltransferase val158met gene polymorphism. Psychol Med (2008) 1-8
    • (2008) Psychol Med , pp. 1-8
    • Roussos, P.1    Giakoumaki, S.G.2    Rogdaki, M.3    Pavlakis, S.4    Frangou, S.5    Bitsios, P.6
  • 171
    • 30844456191 scopus 로고    scopus 로고
    • Gaba-based therapeutic approaches: gabaa receptor subtype functions
    • Rudolph U., and Möhler H. Gaba-based therapeutic approaches: gabaa receptor subtype functions. Curr Opin Pharmacol 6 (2006) 18-23
    • (2006) Curr Opin Pharmacol , vol.6 , pp. 18-23
    • Rudolph, U.1    Möhler, H.2
  • 172
    • 43949141596 scopus 로고    scopus 로고
    • Alteration of bace1-dependent nrg1/erbb4 signaling and schizophrenia-like phenotypes in bace1-null mice
    • Savonenko A.V., Melnikova T., Laird F.M., Stewart K.A., Price D.L., and Wong P.C. Alteration of bace1-dependent nrg1/erbb4 signaling and schizophrenia-like phenotypes in bace1-null mice. Proc Natl Acad Sci 105 (2008) 5585-5590
    • (2008) Proc Natl Acad Sci , vol.105 , pp. 5585-5590
    • Savonenko, A.V.1    Melnikova, T.2    Laird, F.M.3    Stewart, K.A.4    Price, D.L.5    Wong, P.C.6
  • 173
    • 34548700217 scopus 로고    scopus 로고
    • Selective breeding of reduced sensorimotor gating in Wistar rats
    • Schwabe K., Freudenberg F., and Koch M. Selective breeding of reduced sensorimotor gating in Wistar rats. Behav Genet 37 (2007) 706-712
    • (2007) Behav Genet , vol.37 , pp. 706-712
    • Schwabe, K.1    Freudenberg, F.2    Koch, M.3
  • 174
    • 0016592484 scopus 로고
    • Antipsychotic drugs: direct correlation between clinical potency and presynaptic action on dopamine neurons
    • Seeman P., and Lee T. Antipsychotic drugs: direct correlation between clinical potency and presynaptic action on dopamine neurons. Science 188 (1975) 1217-1219
    • (1975) Science , vol.188 , pp. 1217-1219
    • Seeman, P.1    Lee, T.2
  • 175
    • 0019405560 scopus 로고
    • Stimulant-induced psychosis: an evaluation of animal models
    • Youdim M.B.H., Lovenberg W., Sharman D.F., and Lagnado J.R. (Eds), John Wiley & Sons, New York
    • Segal D.S., Geyer M.A., and Schuckit A. Stimulant-induced psychosis: an evaluation of animal models. In: Youdim M.B.H., Lovenberg W., Sharman D.F., and Lagnado J.R. (Eds). Essays in neurochemistry and neuropharmacology (1981), John Wiley & Sons, New York 95-130
    • (1981) Essays in neurochemistry and neuropharmacology , pp. 95-130
    • Segal, D.S.1    Geyer, M.A.2    Schuckit, A.3
  • 176
    • 0032054478 scopus 로고    scopus 로고
    • Dopamine axon varicosities in the prelimbic division of the rat prefrontal cortex exhibit sparse immunoreactivity for the dopamine transporter
    • Sesack S.R., Hawrylak V.A., Matus C., Guido M.A., and Levey A.I. Dopamine axon varicosities in the prelimbic division of the rat prefrontal cortex exhibit sparse immunoreactivity for the dopamine transporter. J Neurosci 18 (1998) 2697-2708
    • (1998) J Neurosci , vol.18 , pp. 2697-2708
    • Sesack, S.R.1    Hawrylak, V.A.2    Matus, C.3    Guido, M.A.4    Levey, A.I.5
  • 177
    • 58149174266 scopus 로고    scopus 로고
    • Schizophrenia-related neural and behavioral phenotypes in transgenic mice expressing truncated disc1
    • Shen S., Lang B., Nakamoto C., Zhang F., Pu J., Kuan S.-L., et al. Schizophrenia-related neural and behavioral phenotypes in transgenic mice expressing truncated disc1. J Neurosci 28 (2008) 10893-10904
    • (2008) J Neurosci , vol.28 , pp. 10893-10904
    • Shen, S.1    Lang, B.2    Nakamoto, C.3    Zhang, F.4    Pu, J.5    Kuan, S.-L.6
  • 178
    • 0037218688 scopus 로고    scopus 로고
    • Maternal influenza infection causes marked behavioral and pharmacological changes in the offspring
    • Shi L., Fatemi S.H., Sidwell R.W., and Patterson P.H. Maternal influenza infection causes marked behavioral and pharmacological changes in the offspring. J Neurosci 23 (2003) 297-302
    • (2003) J Neurosci , vol.23 , pp. 297-302
    • Shi, L.1    Fatemi, S.H.2    Sidwell, R.W.3    Patterson, P.H.4
  • 179
    • 46849120124 scopus 로고    scopus 로고
    • Prepulse inhibition of the startle reflex depends on the catechol O-methyltransferase Val158Met gene polymorphism
    • Roussos P., Giakoumaki S.G., Rogdaki M., Pavlakis S., Frangou S., and Bitsios P. Prepulse inhibition of the startle reflex depends on the catechol O-methyltransferase Val158Met gene polymorphism. Psychol Med 38 (2008) 1651-1658
    • (2008) Psychol Med , vol.38 , pp. 1651-1658
    • Roussos, P.1    Giakoumaki, S.G.2    Rogdaki, M.3    Pavlakis, S.4    Frangou, S.5    Bitsios, P.6
  • 180
    • 0028908937 scopus 로고
    • 8-oh-dpat disruption of prepulse inhibition in rats: reversal with (+)way 100,135 and localization of site of action
    • Sipes T.A., and Geyer M.A. 8-oh-dpat disruption of prepulse inhibition in rats: reversal with (+)way 100,135 and localization of site of action. Psychopharmacology (Berl) 117 (1995) 41-48
    • (1995) Psychopharmacology (Berl) , vol.117 , pp. 41-48
    • Sipes, T.A.1    Geyer, M.A.2
  • 181
    • 35148872226 scopus 로고    scopus 로고
    • Maternal immune activation alters fetal brain development through interleukin-6
    • Smith S.E.P., Li J., Garbett K., Mirnics K., and Patterson P.H. Maternal immune activation alters fetal brain development through interleukin-6. J Neurosci 27 (2007) 10695-10702
    • (2007) J Neurosci , vol.27 , pp. 10695-10702
    • Smith, S.E.P.1    Li, J.2    Garbett, K.3    Mirnics, K.4    Patterson, P.H.5
  • 182
  • 183
    • 4544246380 scopus 로고    scopus 로고
    • Pharmacological and genetic evidence indicates that combined inhibition of nr2a and nr2b subunit containing nmda receptors is required to disrupt prepulse inhibition
    • Spooren W., Mombereau C., Maco M., Gill R., Kemp J.A., Ozmen L., et al. Pharmacological and genetic evidence indicates that combined inhibition of nr2a and nr2b subunit containing nmda receptors is required to disrupt prepulse inhibition. Psychopharmacology (Berl) 175 (2004) 99-105
    • (2004) Psychopharmacology (Berl) , vol.175 , pp. 99-105
    • Spooren, W.1    Mombereau, C.2    Maco, M.3    Gill, R.4    Kemp, J.A.5    Ozmen, L.6
  • 184
    • 4644362935 scopus 로고    scopus 로고
    • Variation in catechol-o-methyltransferase val158 met genotype associated with schizotype but not cognition: a population study in 543 young men
    • Stefanis N.C., Van Os J., Avramopoulos D., Smyrnis N., Evdokimidis I., Hantoumi I., et al. Variation in catechol-o-methyltransferase val158 met genotype associated with schizotype but not cognition: a population study in 543 young men. Biol Psychiatry 56 (2004) 510-515
    • (2004) Biol Psychiatry , vol.56 , pp. 510-515
    • Stefanis, N.C.1    Van Os, J.2    Avramopoulos, D.3    Smyrnis, N.4    Evdokimidis, I.5    Hantoumi, I.6
  • 186
    • 11144356499 scopus 로고    scopus 로고
    • Selective, orally active γ-aminobutyric acida α5 receptor inverse agonists as cognition enhancers
    • Sternfeld F., Carling R.W., Jelley R.A., Ladduwahetty T., Merchant K.J., Moore K.W., et al. Selective, orally active γ-aminobutyric acida α5 receptor inverse agonists as cognition enhancers. J Med Chem 47 (2004) 2176-2179
    • (2004) J Med Chem , vol.47 , pp. 2176-2179
    • Sternfeld, F.1    Carling, R.W.2    Jelley, R.A.3    Ladduwahetty, T.4    Merchant, K.J.5    Moore, K.W.6
  • 187
    • 33745698334 scopus 로고    scopus 로고
    • Schizophrenia genes-famine to feast
    • Straub R.E., and Weinberger D.R. Schizophrenia genes-famine to feast. Biol Psychiatry 60 (2006) 81-83
    • (2006) Biol Psychiatry , vol.60 , pp. 81-83
    • Straub, R.E.1    Weinberger, D.R.2
  • 188
    • 0344305525 scopus 로고    scopus 로고
    • Schizophrenia as a complex trait: evidence from a meta-analysis of twin studies
    • Sullivan P.F., Kendler K.S., and Neale M.C. Schizophrenia as a complex trait: evidence from a meta-analysis of twin studies. Arch Gen Psychiatry 60 (2003) 1187-1192
    • (2003) Arch Gen Psychiatry , vol.60 , pp. 1187-1192
    • Sullivan, P.F.1    Kendler, K.S.2    Neale, M.C.3
  • 189
    • 0027503379 scopus 로고
    • A preliminary assessment of sensorimotor gating in patients with obsessive compulsive disorder
    • Swerdlow N.R., Benbow C.H., Zisook S., Geyer M.A., and Braff D.L. A preliminary assessment of sensorimotor gating in patients with obsessive compulsive disorder. Biol Psychiatry 33 (1993) 298-301
    • (1993) Biol Psychiatry , vol.33 , pp. 298-301
    • Swerdlow, N.R.1    Benbow, C.H.2    Zisook, S.3    Geyer, M.A.4    Braff, D.L.5
  • 190
    • 0034927844 scopus 로고    scopus 로고
    • Neural circuit regulation of prepulse inhibition of startle in the rat: current knowledge and future challenges
    • Swerdlow N.R., Geyer M.A., and Braff D.L. Neural circuit regulation of prepulse inhibition of startle in the rat: current knowledge and future challenges. Psychopharmacology (Berl) 156 (2001) 194-215
    • (2001) Psychopharmacology (Berl) , vol.156 , pp. 194-215
    • Swerdlow, N.R.1    Geyer, M.A.2    Braff, D.L.3
  • 191
    • 33244495280 scopus 로고    scopus 로고
    • Convergence and divergence in the neurochemical regulation of prepulse inhibition of startle and n40 suppression in rats
    • Swerdlow N.R., Geyer M.A., Shoemaker J.M., Light G.A., Braff D.L., Stevens K.E., et al. Convergence and divergence in the neurochemical regulation of prepulse inhibition of startle and n40 suppression in rats. Neuropsychopharmacology 31 (2006) 506-515
    • (2006) Neuropsychopharmacology , vol.31 , pp. 506-515
    • Swerdlow, N.R.1    Geyer, M.A.2    Shoemaker, J.M.3    Light, G.A.4    Braff, D.L.5    Stevens, K.E.6
  • 192
    • 0035886368 scopus 로고    scopus 로고
    • Tactile prepuff inhibition of startle in children with Tourette's syndrome: in search of an "Fmri-friendly" Startle paradigm
    • Swerdlow N.R., Karban B., Ploum Y., Sharp R., Geyer M.A., and Eastvold A. Tactile prepuff inhibition of startle in children with Tourette's syndrome: in search of an "Fmri-friendly" Startle paradigm. Biol Psychiatry 50 (2001) 578-585
    • (2001) Biol Psychiatry , vol.50 , pp. 578-585
    • Swerdlow, N.R.1    Karban, B.2    Ploum, Y.3    Sharp, R.4    Geyer, M.A.5    Eastvold, A.6
  • 193
    • 33845325470 scopus 로고    scopus 로고
    • Startle gating deficits in a large cohort of patients with schizophrenia: relationship to medications, symptoms, neurocognition, and level of function
    • Swerdlow N.R., Light G.A., Cadenhead K.S., Sprock J., Hsieh M.H., and Braff D.L. Startle gating deficits in a large cohort of patients with schizophrenia: relationship to medications, symptoms, neurocognition, and level of function. Arch Gen Psychiatry 63 (2006) 1325-1335
    • (2006) Arch Gen Psychiatry , vol.63 , pp. 1325-1335
    • Swerdlow, N.R.1    Light, G.A.2    Cadenhead, K.S.3    Sprock, J.4    Hsieh, M.H.5    Braff, D.L.6
  • 194
    • 0034212912 scopus 로고    scopus 로고
    • Toward understanding the biology of a complex phenotype: rat strain and substrain differences in the sensorimotor gating-disruptive effects of dopamine agonists
    • Swerdlow N.R., Martinez Z.A., Hanlon F.M., Platten A., Farid M., Auerbach P., et al. Toward understanding the biology of a complex phenotype: rat strain and substrain differences in the sensorimotor gating-disruptive effects of dopamine agonists. J Neurosci 20 (2000) 4325-4336
    • (2000) J Neurosci , vol.20 , pp. 4325-4336
    • Swerdlow, N.R.1    Martinez, Z.A.2    Hanlon, F.M.3    Platten, A.4    Farid, M.5    Auerbach, P.6
  • 196
    • 4344580377 scopus 로고    scopus 로고
    • Heritable differences in the dopaminergic regulation of sensorimotor gating. I. Apomorphine effects on startle gating in albino and hooded outbred rat strains and their f1 and n2 progeny
    • Swerdlow N.R., Shoemaker J.M., Platten A., Pitcher L., Goins J., and Auerbach P.P. Heritable differences in the dopaminergic regulation of sensorimotor gating. I. Apomorphine effects on startle gating in albino and hooded outbred rat strains and their f1 and n2 progeny. Psychopharmacology (Berl) 174 (2004) 441-451
    • (2004) Psychopharmacology (Berl) , vol.174 , pp. 441-451
    • Swerdlow, N.R.1    Shoemaker, J.M.2    Platten, A.3    Pitcher, L.4    Goins, J.5    Auerbach, P.P.6
  • 197
    • 46649110318 scopus 로고    scopus 로고
    • Realistic expectations of prepulse inhibition in translational models for schizophrenia research
    • Swerdlow N.R., Weber M., Qu Y., Light G.A., and Braff D.L. Realistic expectations of prepulse inhibition in translational models for schizophrenia research. Psychopharmacology (Berl) 199 (2008) 331-388
    • (2008) Psychopharmacology (Berl) , vol.199 , pp. 331-388
    • Swerdlow, N.R.1    Weber, M.2    Qu, Y.3    Light, G.A.4    Braff, D.L.5
  • 199
    • 0034906626 scopus 로고    scopus 로고
    • Roles of the glutamate receptor epsilon2 and delta2 subunits in the potentiation and prepulse inhibition of the acoustic startle reflex
    • Takeuchi T., Kiyama Y., Nakamura K., Tsujita M., Matsuda I., Mori H., et al. Roles of the glutamate receptor epsilon2 and delta2 subunits in the potentiation and prepulse inhibition of the acoustic startle reflex. Eur J Neurosci 14 (2001) 153-160
    • (2001) Eur J Neurosci , vol.14 , pp. 153-160
    • Takeuchi, T.1    Kiyama, Y.2    Nakamura, K.3    Tsujita, M.4    Matsuda, I.5    Mori, H.6
  • 200
    • 34548830450 scopus 로고    scopus 로고
    • Schizophrenia endophenotypes as treatment targets
    • Thaker G.K. Schizophrenia endophenotypes as treatment targets. Expert Opin Ther Targets 11 (2007) 1189-1206
    • (2007) Expert Opin Ther Targets , vol.11 , pp. 1189-1206
    • Thaker, G.K.1
  • 201
    • 40749090843 scopus 로고    scopus 로고
    • Prepulse inhibition (ppi) of tactile startle response in recombinant congenic strains of mice: Qtl mapping and comparison with acoustic ppi
    • Torkamanzehi A., Boksa P., and Joober R. Prepulse inhibition (ppi) of tactile startle response in recombinant congenic strains of mice: Qtl mapping and comparison with acoustic ppi. J Genet Genom 35 (2008) 139-151
    • (2008) J Genet Genom , vol.35 , pp. 139-151
    • Torkamanzehi, A.1    Boksa, P.2    Joober, R.3
  • 203
    • 0032403626 scopus 로고    scopus 로고
    • d-Serine added to antipsychotics for the treatment of schizophrenia
    • Tsai G., Yang P., Chung L.C., Lange N., and Coyle J.T. d-Serine added to antipsychotics for the treatment of schizophrenia. Biol Psychiatry 44 (1998) 1081-1089
    • (1998) Biol Psychiatry , vol.44 , pp. 1081-1089
    • Tsai, G.1    Yang, P.2    Chung, L.C.3    Lange, N.4    Coyle, J.T.5
  • 204
    • 33745703902 scopus 로고    scopus 로고
    • Catechol-o-methyltransferase, cognition, and psychosis: Val158met and beyond
    • Tunbridge E.M., Harrison P.J., and Weinberger D.R. Catechol-o-methyltransferase, cognition, and psychosis: Val158met and beyond. Biol Psychiatry 60 (2006) 141-151
    • (2006) Biol Psychiatry , vol.60 , pp. 141-151
    • Tunbridge, E.M.1    Harrison, P.J.2    Weinberger, D.R.3
  • 205
    • 33845870142 scopus 로고    scopus 로고
    • Neurophysiological endophenotypes of schizophrenia: the viability of selected candidate measures
    • Turetsky B.I., Calkins M.E., Light G.A., Olincy A., Radant A.D., and Swerdlow N.R. Neurophysiological endophenotypes of schizophrenia: the viability of selected candidate measures. Schizophr Bull 33 (2007) 69-94
    • (2007) Schizophr Bull , vol.33 , pp. 69-94
    • Turetsky, B.I.1    Calkins, M.E.2    Light, G.A.3    Olincy, A.4    Radant, A.D.5    Swerdlow, N.R.6
  • 206
    • 0032974130 scopus 로고    scopus 로고
    • d-Cycloserine increases positive symptoms in chronic schizophrenic patients when administered in addition to antipsychotics: a double-blind, parallel, placebo-controlled study
    • van Berckel B.N., Evenblij C.N., van Loon B.J., Maas M.F., van der Geld M.A., Wynne H.J., et al. d-Cycloserine increases positive symptoms in chronic schizophrenic patients when administered in addition to antipsychotics: a double-blind, parallel, placebo-controlled study. Neuropsychopharmacology 21 (1999) 203-210
    • (1999) Neuropsychopharmacology , vol.21 , pp. 203-210
    • van Berckel, B.N.1    Evenblij, C.N.2    van Loon, B.J.3    Maas, M.F.4    van der Geld, M.A.5    Wynne, H.J.6
  • 207
    • 0031808942 scopus 로고    scopus 로고
    • The effects of low dose ketamine on sensory gating, neuroendocrine secretion and behavior in healthy human subjects
    • van Berckel B.N., Oranje B., van Ree J.M., Verbaten M.N., and Kahn R.S. The effects of low dose ketamine on sensory gating, neuroendocrine secretion and behavior in healthy human subjects. Psychopharmacology (Berl) 137 (1998) 271-281
    • (1998) Psychopharmacology (Berl) , vol.137 , pp. 271-281
    • van Berckel, B.N.1    Oranje, B.2    van Ree, J.M.3    Verbaten, M.N.4    Kahn, R.S.5
  • 208
    • 57149142243 scopus 로고    scopus 로고
    • Heritable strain differences in sensitivity to the startle gating-disruptive effects of d2 but not d3 receptor stimulation
    • Weber M., Chang W.L., Breier M., Ko D., and Swerdlow N.R. Heritable strain differences in sensitivity to the startle gating-disruptive effects of d2 but not d3 receptor stimulation. Behav Pharmacol 19 (2008) 786-795
    • (2008) Behav Pharmacol , vol.19 , pp. 786-795
    • Weber, M.1    Chang, W.L.2    Breier, M.3    Ko, D.4    Swerdlow, N.R.5
  • 209
    • 0342313718 scopus 로고    scopus 로고
    • Homer: a link between neural activity and glutamate receptor function
    • Xiao B., Tu J.C., and Worley P.F. Homer: a link between neural activity and glutamate receptor function. Curr Opin Neurobiol 10 (2000) 370-374
    • (2000) Curr Opin Neurobiol , vol.10 , pp. 370-374
    • Xiao, B.1    Tu, J.C.2    Worley, P.F.3
  • 210
    • 33748808963 scopus 로고    scopus 로고
    • Norepinephrine transporter blockade can normalize the prepulse inhibition deficits found in dopamine transporter knockout mice
    • Yamashita M., Fukushima S., Shen H.W., Hall F.S., Uhl G.R., Numachi Y., et al. Norepinephrine transporter blockade can normalize the prepulse inhibition deficits found in dopamine transporter knockout mice. Neuropsychopharmacology 31 (2006) 2132-2139
    • (2006) Neuropsychopharmacology , vol.31 , pp. 2132-2139
    • Yamashita, M.1    Fukushima, S.2    Shen, H.W.3    Hall, F.S.4    Uhl, G.R.5    Numachi, Y.6
  • 211
    • 34548813860 scopus 로고    scopus 로고
    • Site-specific role of catechol-o-methyltransferase in dopamine overflow within prefrontal cortex and dorsal striatum
    • Yavich L., Forsberg M.M., Karayiorgou M., Gogos J.A., and Mannisto P.T. Site-specific role of catechol-o-methyltransferase in dopamine overflow within prefrontal cortex and dorsal striatum. J Neurosci 27 (2007) 10196-10209
    • (2007) J Neurosci , vol.27 , pp. 10196-10209
    • Yavich, L.1    Forsberg, M.M.2    Karayiorgou, M.3    Gogos, J.A.4    Mannisto, P.T.5
  • 212
    • 8144226853 scopus 로고    scopus 로고
    • GABA receptors containing the alpha5 subunit mediate the trace effect in aversive and appetitive conditioning and extinction of conditioned fear
    • Yee B.K., Hauser J., Dolgov V.V., Keist R., Möhler H., Rudolph U., et al. GABA receptors containing the alpha5 subunit mediate the trace effect in aversive and appetitive conditioning and extinction of conditioned fear. Eur J Neurosci 20 (2004) 1928-1936
    • (2004) Eur J Neurosci , vol.20 , pp. 1928-1936
    • Yee, B.K.1    Hauser, J.2    Dolgov, V.V.3    Keist, R.4    Möhler, H.5    Rudolph, U.6
  • 213
    • 28044453713 scopus 로고    scopus 로고
    • A schizophrenia-related sensorimotor deficit links alpha 3-containing gabaa receptors to a dopamine hyperfunction
    • Yee B.K., Keist R., von Boehmer L., Studer R., Benke D., Hagenbuch N., et al. A schizophrenia-related sensorimotor deficit links alpha 3-containing gabaa receptors to a dopamine hyperfunction. Proc Natl Acad Sci USA 102 (2005) 17154-17159
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 17154-17159
    • Yee, B.K.1    Keist, R.2    von Boehmer, L.3    Studer, R.4    Benke, D.5    Hagenbuch, N.6
  • 215
    • 64249168387 scopus 로고    scopus 로고
    • Using the MATRICS to guide development of a preclinical cognitive test battery for research in schizophrenia
    • Young J.W., Powell S.B., Risbrough V., Marston H.M., and Geyer M.A. Using the MATRICS to guide development of a preclinical cognitive test battery for research in schizophrenia. Pharmacol Ther 122 (2009) 150-202
    • (2009) Pharmacol Ther , vol.122 , pp. 150-202
    • Young, J.W.1    Powell, S.B.2    Risbrough, V.3    Marston, H.M.4    Geyer, M.A.5
  • 216
    • 0036298997 scopus 로고    scopus 로고
    • A selective reduction in the relative density of parvalbumin-immunoreactive neurons in the hippocampus in schizophrenia patients
    • Zhang Z., Sun J., and Reynolds G.P. A selective reduction in the relative density of parvalbumin-immunoreactive neurons in the hippocampus in schizophrenia patients. Chin Med J 115 (2002) 819-823
    • (2002) Chin Med J , vol.115 , pp. 819-823
    • Zhang, Z.1    Sun, J.2    Reynolds, G.P.3
  • 217
    • 40849096169 scopus 로고    scopus 로고
    • Does disrupted-in-schizophrenia (disc1) generate fusion transcripts?
    • Zhou X., Geyer M.A., and Kelsoe J.R. Does disrupted-in-schizophrenia (disc1) generate fusion transcripts?. Mol Psychiatry 13 (2008) 361-363
    • (2008) Mol Psychiatry , vol.13 , pp. 361-363
    • Zhou, X.1    Geyer, M.A.2    Kelsoe, J.R.3
  • 218
    • 16844371331 scopus 로고    scopus 로고
    • Reduced expression of the sp4 gene in mice causes deficits in sensorimotor gating and memory associated with hippocampal vacuolization
    • Zhou X., Long J.M., Geyer M.A., Masliah E., Kelsoe J.R., Wynshaw-Boris A., et al. Reduced expression of the sp4 gene in mice causes deficits in sensorimotor gating and memory associated with hippocampal vacuolization. Mol Psychiatry 10 (2004) 393-406
    • (2004) Mol Psychiatry , vol.10 , pp. 393-406
    • Zhou, X.1    Long, J.M.2    Geyer, M.A.3    Masliah, E.4    Kelsoe, J.R.5    Wynshaw-Boris, A.6


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