Variation in DISC1 affects hippocampal structure and function and increases risk for schizophrenia

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 24, 2005, Pages 8627-8632

  Callicott, Joseph H ^a,b   Straub, Richard E ^a   Pezawas, Lukas ^a   Egan, Michael F ^a   Mattay, Venkata S ^a   Hariri, Ahmad R ^a   Verchinski, Beth A ^a   Meyer Lindenberg, Andreas ^a   Balkissoon, Rishi ^a   Kolachana, Bhaskar ^a   Goldberg, Terry E ^a   Weinberger, Daniel R ^a,b  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^b MSC 1364 ^*  (United States)

Author keywords

Association; Hippocampus; Morphometry

Indexed keywords

ADULT; ALLELE; ARTICLE; BRAIN FUNCTION; COGNITION; CONTROLLED STUDY; DISC1 GENE; FAMILY STUDY; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; GENE; GENETIC EPIDEMIOLOGY; GENETIC RISK; GENETIC VARIABILITY; GRAY MATTER; HAPLOTYPE; HIPPOCAMPUS; HUMAN; MAJOR CLINICAL STUDY; MALE; NEUROANATOMY; NEUROPSYCHIATRY; PHENOTYPE; PRIORITY JOURNAL; SCHIZOPHRENIA; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; AFRICAN AMERICANS; ALLELES; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; HAPLOTYPES; HIPPOCAMPUS; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; NERVE TISSUE PROTEINS; POLYMORPHISM, SINGLE NUCLEOTIDE; PSYCHOMOTOR PERFORMANCE; RISK FACTORS; SCHIZOPHRENIA;

EID: 20844463251     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0500515102     Document Type: Article

References (49)

1. Weinberger, D. R. (1999) Biol. Psychiatry 45, 395-402.
2. Nelson, M. D., Saykin, A. J., Flashman, L. A. & Riordan, H. J. (1998) Arch. Gen. Psychiatry 55, 433-440.
3. Bertolino, A., Nawroz, S., Mattay, V. S., Barnett, A. S., Duyn, J. H., Moonen, C. T., Frank, J. A., Tedeschi, G. & Weinberger, D. R. (1996) Am. J. Psychiatry 153, 1554-1563.
4. Freedman, R., Waldo, M., Bickford-Wimer, P. & Nagamoto, H. (1991) Schizophr. Res. 4, 233-243.
5. Goldberg, T. E., Torrey, E. F., Gold, J. M., Ragland, J. D., Bigelow, L. B. & Weinberger, D. R. (1993) Psychol. Med. 23, 71-85.
6. Heckers, S., Rauch, S. L., Goff, D., Savage, C. R., Schacter, D. L., Fischman, A. J. & Alpert, N. M. (1998) Nat. Neurosci, 1, 318-323.
7. Sawa, A. & Snyder, S. H. (2002) Science 296, 692-695.
8. Black-wood, D. H., Fordyce, A., Walker, M. T., St. Clair, D. M., Porteous, D. J. & Muir, W. J. (2001) Am. J. Hum. Genet. 69, 428-433.
9. St. Clair, D., Blackwood, D., Muir, W., Carothers, A., Walker, M., Spowart, G., Gosden, C. & Evans, H. J. (1990) Lancet 336, 13-16.
10. Millar, J. K., Wilson-Annan, J. C., Anderson, S., Christie, S., Taylor, M. S., Semple, C. A., Devon, R. S., Clair, D. M., Muir, W. J., Blackwood, D. H. & Porteous, D. J. (2000) Hum. Mol. Genet. 9, 1415-1423.
11. Devon, R. S., Anderson, S., Teague, P. W., Burgess, P., Kipari, T. M., Semple, C. A., Millar, J. K., Muir, W. J., Murray, V., Pelosi, A. J., et al. (2001) Psychiatr. Genet. 11, 71-78.
12. Hennah, W., Varilo, T., Kestila, M., Paunio, T., Arajarvi, R., Haukka, J., Parker, A., Martin, R., Levitzky, S., Partonen, T., et al. (2003) Hum. Mol. Genet. 12, 3151-3159.
13. Ekelund, J., Hennah, W., Hiekkalinna, T., Parker, A., Meyer, J., Lonnqvist, J. & Peltonen, L. (2004) Mol. Psychiatry 9, 1037-1041.
14. Hodgkinson, C. A., Goldman, D., Jaeger, J., Persaud, S., Kane, J. M., Lipsky, R. H. & Malhotra, A. K. (2004) Am. J. Hum. Genet. 75, 862-872.
15. Weiss, K. M. & Terwilliger, J. D. (2000) Nat. Genet. 26, 151-157.
16. Weinberger, D. R., Egan, M. F., Bertolino, A., Callicott, J. H., Mattay, V. S., Lipska, B. K., Berman, K. F. & Goldberg, T. E. (2001) Biol. Psychiatry 50, 825-844.
17. Taylor, M. S., Devon, R. S., Millar, J. K. & Porteous, D. J. (2003) Genomics 81, 67-77.
18. Morris, J. A., Kandpal, G., Ma, L. & Austin, C. P. (2003) Hum. Mol. Genet. 12, 1591-1608.
19. Austin, C. P., Ky, B., Ma, L., Morris, J. A. & Shughrue, P. J. (2004) Neuroscience 124, 3-10.
20. Ma, L., Liu, Y., Ky, B., Shughrue, P. J., Austin, C. P. & Morris, J. A. (2002) Genomics 80, 662-672.
21. Austin, C. P., Ma, L., Ky. B., Morris, J. A. & Shughrue, P. J. (2003) NeuroReport 14, 951-954.
22. Miyoshi, K., Honda, A., Baba, K., Taniguchi, M., Oono, K., Fujita, T., Kuroda, S., Katayama, T. & Tohyama, M. (2003) Mol. Psychiatry 8, 685-694.
23. Ozeki, Y., Tomoda, T., Kleiderlein, J., Kamiya, A., Bord, L., Fujii, K., Okawa, M., Yamada, N., Hatten, M. E., Snyder, S. H., Ross, C. A. & Sawa, A. (2003) Proc. Natl. Acad. Sci. USA 100, 289-294.
24. Egan, M. F., Goldberg, T. E., Gscheidle, T., Weirich, M., Bigelow, L. B. & Weinberger, D. R. (2000) Am. J. Psychiatry 157, 1309-1316.
25. Cloninger, C. R., Kaufmann, C. A., Faraone, S. V., Malaspina, D., Svrakic, D. M., Harkavy-Friedman, J., Suarez, B. K., Matise, T. C., Shore, D., Lee, H., et al. (1998) Am. J. Med. Genet. 81, 275-281.
26. Livak, K. J. (1999) Genet. Anal. 14, 143-149.
27. Clayton, D. (1999) Am. J. Hum. Genet. 65, 1170-1177.
28. Abecasis, G. R., Cherny, W. O., Cookson, W. O. & Cardon, L. R. (2002) Nat. Gener. 30, 97-101.
29. Spielman, R. S. & Ewens, W. J. (1998) Am. J. Hum. Genet. 62, 450-458.
30. Abecasis, G. R. & Cookson, W. O. (2000) Bioinformatics 16, 182-183.
31. Good, C. D., Johnsrude, L. S., Ashburner, J., Henson, R. N., Friston, K. J. & Frackowiak, R. S. (2001) NeuroImage 14, 21-36.
32. Pezawas, L., Verchinski, B. A., Mattay, V. S., Callicott, J. H., Kolachana, B. S., Straub, R. E., Egan, M. F., Meyer-Lindenberg, A. & Weinberger, D. R. (2004) J. Neurosci. 24, 10099-10102.
33. Buchel, C., Wise, R. J., Mummery, C. J., Poline, J. B. & Friston, K. J. (1996) NeuroImage 4, 60-66.
34. Maldjian, J. A., Laurienti, P. J., Kraft, R. A. & Burdette, J. H. (2003) NeuroImage 19, 1233-1239,
35. Callicott, J. H., Mattay, V. S., Bertolino, A., Finn, K., Coppola, R., Frank, J. A., Goldberg, T. E. & Weinberger, D. R. (1999) Cereb. Cortex 9, 20-26.
36. Hariri, A. R., Goldberg, T. E., Mattay, V. S., Kolachana, B. S., Callicott, J. H., Egan, M. F. & Weinberger, D. R. (2003) J. Neurosci. 23, 6690-6694.
37. Hariri, A. R., Mattay, V. S., Tessitore, A., Kolachana, B., Fera, F., Goldman, D., Egan, M. F. & Weinberger, D. R. (2002) Science 297, 400-403.
38. Callicott, J. H., Egan, M. F., Mattay, V. S., Bertolino, A., Bone, A. D., Verchinksi, B. & Weinberger, D. R. (2003) Am. J. Psychiatry 160, 709-719.
39. Callicott, J. H., Mattay, V. S., Verchinski, B. A., Marenco, S., Egan, M. F. & Weinberger, D. R. (2003) Am. J. Psychiatry 160, 2209-2215.
40. Egan, M. F., Goldberg, T. E., Gscheidle, T., Weirich, M., Rawlings, R., Hyde, T. M., Bigelow, L. & Weinberger, D. R. (2001) Biol. Psychiatry 50, 98-107.
41. Jastak, S. & Wilkinson, G. (1984) Wide Range Achievement Test-Revised (Jastak Associates, Wilmington, DE).
42. Egan, M. F., Callicott, J. H., Kojima, M., Goldberg, T. E., Kolachana, B. S., Bertolino, A., Zaitsev, E., Gold, B., Goldman, D., Dean, M., Lu, B. & Weinberger, D. R. (2003) Cell 112, 257-269.
43. Bookheimer, S. Y., Strojwas, M. H., Cohen, M. S., Saunders, A. M., Pericak-Vance, M. A., Mazziotta, J. C. & Small, G. W. (2000) N. Engl. J. Med. 343, 450-456.
44. Kremen, W. S., Faraone, S. V., Seidman, L. J., Pepple, J. R. & Tsuang, M. T. (1998) Psychiatry Res. 79, 227-240.
45. Miller, L. A., Lai, R. & Munoz, D. G. (1998) Neuropsychologia 36, 1247-1256.
46. Bilder, R. M., Bogerts, B., Ashtari, M., Wu, H., Alvir, J. M., Jody, D., Reiter, G., Bell, L. & Lieberman, J. A. (1995) Schizophr. Res. 17, 47-58.
47. Glabus, M. F., Horwitz, B., Holt, J. L., Kohn, P. D., Gerton, B. K., Callicott, J. H., Meyer-Lindenberg, A. & Berman, K. F. (2003) Cereb. Cortex 13, 1352-1361.
48. Egan, M. F., Goldberg, T. E., Kolachana, B. S., Callicott, J. H., Mazzanti, C. M., Straub, R. E., Goldman, D. & Weinberger, D. R. (2001) Proc. Natl. Acad. Sci. USA 98, 6917-6922.
49. Gasperoni, T. L., Ekelund, J., Huttunen, M., Palmer, C. G., Tuulio-Henriksson, A., Lonnqvist, J., Kaprio, J., Peltonen, L. & Cannon, T. D. (2003) Am. J. Med. Genet. 116, 8-16.