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Volumn 183, Issue 1, 2009, Pages 533-542

In vivo lipopolysaccharide exposure of human blood leukocytes induces cross-tolerance to multiple TLR ligands

Author keywords

[No Author keywords available]

Indexed keywords

ESCHERICHIA COLI LIPOPOLYSACCHARIDE; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 3; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 5; TOLL LIKE RECEPTOR 7; TUMOR NECROSIS FACTOR; CYTOKINE; LIGAND; TLR2 PROTEIN, HUMAN; TLR3 PROTEIN, HUMAN; TLR5 PROTEIN, HUMAN; TLR7 PROTEIN, HUMAN; TOLL LIKE RECEPTOR 3;

EID: 68949103827     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0802189     Document Type: Article
Times cited : (86)

References (89)
  • 1
    • 0017260895 scopus 로고
    • Granulocyte function in experimental human endotoxemia
    • Territo, M. C., and D. W. Golde. 1976. Granulocyte function in experimental human endotoxemia. Blood 47: 539-544.
    • (1976) Blood , vol.47 , pp. 539-544
    • Territo, M.C.1    Golde, D.W.2
  • 2
    • 0033805417 scopus 로고    scopus 로고
    • Reduced ex vivo chemokine production by polymorphonuclear cells after in vivo exposure of normal humans to endotoxin
    • Schultz, M. J., D. P. Olszyna, E. De Jonge, A. Verbon, S. J. van Deventer, and T. van der Poll. 2000. Reduced ex vivo chemokine production by polymorphonuclear cells after in vivo exposure of normal humans to endotoxin. J. Infect. Dis. 182: 1264-1267.
    • (2000) J. Infect. Dis. , vol.182 , pp. 1264-1267
    • Schultz, M.J.1    Olszyna, D.P.2    De Jonge, E.3    Verbon, A.4    Van Deventer, S.J.5    Van Der Poll, T.6
  • 3
    • 0033963967 scopus 로고    scopus 로고
    • Reduced Th1, but not Th2, cytokine production by lymphocytes after in vivo exposure of healthy subjects to endotoxin
    • Lauw, F. N., T. Ten Hove, P. E. Dekkers, E. De Jonge, S. J. van Deventer, and T. van der Poll. 2000. Reduced Th1, but not Th2, cytokine production by lymphocytes after in vivo exposure of healthy subjects to endotoxin. Infect. Immun. 68: 1014-1018.
    • (2000) Infect. Immun. , vol.68 , pp. 1014-1018
    • Lauw, F.N.1    Ten Hove, T.2    Dekkers, P.E.3    De Jonge, E.4    Van Deventer, S.J.5    Van Der Poll, T.6
  • 5
    • 0029807850 scopus 로고    scopus 로고
    • Changes in endotoxin-induced cytokine production by whole blood after in vivo exposure of normal humans to endotoxin
    • van der Poll, T., S. M. Coyle, L. L. Moldawer, and S. F. Lowry. 1996. Changes in endotoxin-induced cytokine production by whole blood after in vivo exposure of normal humans to endotoxin. J. Infect. Dis. 174: 1356-1360.
    • (1996) J. Infect. Dis. , vol.174 , pp. 1356-1360
    • Van Der Poll, T.1    Coyle, S.M.2    Moldawer, L.L.3    Lowry, S.F.4
  • 6
    • 0036159842 scopus 로고    scopus 로고
    • Endotoxin tolerance: A review
    • West, M. A., and W. Heagy. 2002. Endotoxin tolerance: A review. Crit. Care Med. 30: S64-S73.
    • (2002) Crit. Care Med. , vol.30
    • West, M.A.1    Heagy, W.2
  • 8
  • 9
    • 0027531739 scopus 로고
    • Tolerance to endotoxin-induced expression of the interleukin-1 β gene in blood neutrophils of humans with the sepsis syndrome
    • McCall, C. E., L. M. Grosso-Wilmoth, K. LaRue, R. N. Guzman, and S. L. Cousart. 1993. Tolerance to endotoxin-induced expression of the interleukin-1 β gene in blood neutrophils of humans with the sepsis syndrome. J. Clin. Invest. 91: 853-861.
    • (1993) J. Clin. Invest. , vol.91 , pp. 853-861
    • McCall, C.E.1    Grosso-Wilmoth, L.M.2    LaRue, K.3    Guzman, R.N.4    Cousart, S.L.5
  • 10
    • 67650401419 scopus 로고    scopus 로고
    • Immunosuppression associated with interleukin-1R-associated-kinase-M upregulation predicts mortality in Gram-negative sepsis (melioidosis)
    • Wiersinga, W. J., C. van 't Veer, P. S. van den Pangaart, A. M. Dondorp, N. P. Day, S. J. Peacock, and T. van der Poll. 2009. Immunosuppression associated with interleukin-1R-associated-kinase-M upregulation predicts mortality in Gram-negative sepsis (melioidosis). Crit. Care Med. 37: 569-576.
    • (2009) Crit. Care Med. , vol.37 , pp. 569-576
    • Wiersinga, W.J.1    Van 't Veer, C.2    Van Den Pangaart, P.S.3    Dondorp, A.M.4    Day, N.P.5    Peacock, S.J.6    Van Der Poll, T.7
  • 11
    • 0034913320 scopus 로고    scopus 로고
    • Immunodepression in sepsis and SIRS assessed by ex vivo cytokine production is not a generalized phenomenon: A review
    • Cavaillon, J. M., M. Adib-Conquy, I. Cloez-Tayarani, and C. Fitting. 2001. Immunodepression in sepsis and SIRS assessed by ex vivo cytokine production is not a generalized phenomenon: a review. J. Endotoxin Res. 7: 85-93.
    • (2001) J. Endotoxin Res. , vol.7 , pp. 85-93
    • Cavaillon, J.M.1    Adib-Conquy, M.2    Cloez-Tayarani, I.3    Fitting, C.4
  • 12
    • 0031601755 scopus 로고    scopus 로고
    • Proinflammatory cytokine gene expression in whole blood from patients undergoing coronary artery bypass surgery and its modulation by pentoxifylline
    • Kleinschmidt, S., G. A. Wanner, D. Bussmann, J. P. Kremer, T. Ziegenfuss, M. D. Menger, and M. Bauer. 1998. Proinflammatory cytokine gene expression in whole blood from patients undergoing coronary artery bypass surgery and its modulation by pentoxifylline. Shock 9: 12-20. (Pubitemid 128463869)
    • (1998) Shock , vol.9 , Issue.1 , pp. 12-20
    • Kleinschmidt, S.1    Wanner, G.A.2    Bussmann, D.3    Kremer, J.P.4    Ziegenfuss, T.5    Menger, M.D.6    Bauer, M.7
  • 13
    • 0032931385 scopus 로고    scopus 로고
    • The extent of traumatic damage determines a graded depression of the endotoxin responsiveness of peripheral blood mononuclear cells from patients with blunt injuries
    • Majetschak, M., R. Flach, E. Kreuzfelder, V. Jennissen, T. Heukamp, F. Neudeck, K. P. Schmit-Neuerburg, U. Obertacke, and F. U. Schade. 1999. The extent of traumatic damage determines a graded depression of the endotoxin responsiveness of peripheral blood mononuclear cells from patients with blunt injuries. Crit. Care Med. 27: 313-318. (Pubitemid 29113540)
    • (1999) Critical Care Medicine , vol.27 , Issue.2 , pp. 313-318
    • Majetschak, M.1    Flach, R.2    Kreuzfelder, E.3    Jennissen, V.4    Heukamp, T.5    Neudeck, F.6    Schmit-Neuerburg, K.P.7    Obertacke, U.8    Schade, F.U.9
  • 16
    • 3142724031 scopus 로고    scopus 로고
    • Toll-like receptor signalling
    • Akira, S., and K. Takeda. 2004. Toll-like receptor signalling. Nat. Rev. Immunol. 4: 499-511.
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 499-511
    • Akira, S.1    Takeda, K.2
  • 17
    • 36049033394 scopus 로고    scopus 로고
    • Signaling to NF-κB by Toll-like receptors
    • Kawai, T., and S. Akira. 2007. Signaling to NF-κB by Toll-like receptors. Trends Mol. Med. 13: 460-469.
    • (2007) Trends Mol. Med. , vol.13 , pp. 460-469
    • Kawai, T.1    Akira, S.2
  • 18
    • 20644450804 scopus 로고    scopus 로고
    • Negative regulation of Toll-like receptor-mediated immune responses
    • Liew, F. Y., D. Xu, E. K. Brint, and L. A. O'Neill. 2005. Negative regulation of Toll-like receptor-mediated immune responses. Nat. Rev. Immunol. 5: 446-458.
    • (2005) Nat. Rev. Immunol. , vol.5 , pp. 446-458
    • Liew, F.Y.1    Xu, D.2    Brint, E.K.3    O'Neill, L.A.4
  • 19
    • 33748871187 scopus 로고    scopus 로고
    • The human adaptor SARM negatively regulates adaptor protein TRIF-dependent Toll-like receptor signaling
    • Carty, M., R. Goodbody, M. Schroder, J. Stack, P. N. Moynagh, and A. G. Bowie. 2006. The human adaptor SARM negatively regulates adaptor protein TRIF-dependent Toll-like receptor signaling. Nat. Immunol. 7: 1074-1081.
    • (2006) Nat. Immunol. , vol.7 , pp. 1074-1081
    • Carty, M.1    Goodbody, R.2    Schroder, M.3    Stack, J.4    Moynagh, P.N.5    Bowie, A.G.6
  • 20
    • 0037183979 scopus 로고    scopus 로고
    • Induction of bacterial lipoprotein tolerance is associated with suppression of Toll-like receptor 2 expression
    • Wang, J. H., M. Doyle, B. J. Manning, Q. Di Wu, S. Blankson, and H. P. Redmond. 2002. Induction of bacterial lipoprotein tolerance is associated with suppression of Toll-like receptor 2 expression. J. Biol. Chem. 277: 36068-36075.
    • (2002) J. Biol. Chem. , vol.277 , pp. 36068-36075
    • Wang, J.H.1    Doyle, M.2    Manning, B.J.3    Di Wu, Q.4    Blankson, S.5    Redmond, H.P.6
  • 23
    • 0034671772 scopus 로고    scopus 로고
    • Synergy and cross-tolerance between Toll-like receptor (TLR) 2- and TLR4-mediated signaling pathways
    • Sato, S., F. Nomura, T. Kawai, O. Takeuchi, P. F. Muhlradt, K. Takeda, and S. Akira. 2000. Synergy and cross-tolerance between toll-like receptor (TLR) 2- and TLR4-mediated signaling pathways. J. Immunol. 165: 7096-7101. (Pubitemid 32001184)
    • (2000) Journal of Immunology , vol.165 , Issue.12 , pp. 7096-7101
    • Sato, S.1    Nomura, F.2    Kawai, T.3    Takeuchi, O.4    Muhlradt, P.F.5    Takeda, K.6    Akira, S.7
  • 24
    • 0036319517 scopus 로고    scopus 로고
    • A variety of microbial components induce tolerance to lipopolysaccharide by differentially affecting MyD88-dependent and -independent pathways
    • Sato, S., O. Takeuchi, T. Fujita, H. Tomizawa, K. Takeda, and S. Akira. 2002. A variety of microbial components induce tolerance to lipopolysaccharide by differentially affecting MyD88-dependent and -independent pathways. Int. Immunol. 14: 783-791. (Pubitemid 34814639)
    • (2002) International Immunology , vol.14 , Issue.7 , pp. 783-791
    • Sato, S.1    Takeuchi, O.2    Fujita, T.3    Tomizawa, H.4    Takeda, K.5    Akira, S.6
  • 25
    • 0035871626 scopus 로고    scopus 로고
    • Induction of cross-tolerance by lipopolysaccharide and highly purified lipoteichoic acid via different Toll-like receptors independent of paracrine mediators
    • Lehner, M. D., S. Morath, K. S. Michelsen, R. R. Schumann, and T. Hartung. 2001. Induction of cross-tolerance by lipopolysaccharide and highly purified lipoteichoic acid via different Toll-like receptors independent of paracrine mediators. J. Immunol. 166: 5161-5167.
    • (2001) J. Immunol. , vol.166 , pp. 5161-5167
    • Lehner, M.D.1    Morath, S.2    Michelsen, K.S.3    Schumann, R.R.4    Hartung, T.5
  • 26
    • 0037151080 scopus 로고    scopus 로고
    • Gram-negative flagellin-induced self-tolerance is associated with a block in interleukin-1 receptor-associated kinase release from toll-like receptor 5
    • Mizel, S. B., and J. A. Snipes. 2002. Gram-negative flagellin-induced self-tolerance is associated with a block in interleukin-1 receptor-associated kinase release from toll-like receptor 5. J. Biol. Chem. 277: 22414-22420.
    • (2002) J. Biol. Chem. , vol.277 , pp. 22414-22420
    • Mizel, S.B.1    Snipes, J.A.2
  • 27
    • 0037438350 scopus 로고    scopus 로고
    • CpG DNA induces self and cross-hyporesponsiveness of RAW264.7 cells in response to CpG DNA and lipopolysaccharide: Alterations in IL-1 receptor-associated kinase expression
    • Yeo, S. J., J. G. Yoon, S. C. Hong, and A. K. Yi. 2003. CpG DNA induces self and cross-hyporesponsiveness of RAW264.7 cells in response to CpG DNA and lipopolysaccharide: alterations in IL-1 receptor-associated kinase expression. J. Immunol. 170: 1052-1061.
    • (2003) J. Immunol. , vol.170 , pp. 1052-1061
    • Yeo, S.J.1    Yoon, J.G.2    Hong, S.C.3    Yi, A.K.4
  • 28
    • 25444515154 scopus 로고    scopus 로고
    • Differential effects of CpG-DNA in Toll-like receptor-2/-4/-9 tolerance and cross-tolerance
    • Dalpke, A. H., M. D. Lehner, T. Hartung, and K. Heeg. 2005. Differential effects of CpG-DNA in Toll-like receptor-2/-4/-9 tolerance and cross-tolerance. Immunology 116: 203-212.
    • (2005) Immunology , vol.116 , pp. 203-212
    • Dalpke, A.H.1    Lehner, M.D.2    Hartung, T.3    Heeg, K.4
  • 29
    • 33746431489 scopus 로고    scopus 로고
    • Bacterial lipoprotein-induced self-tolerance and cross-tolerance to LPS are associated with reduced IRAK-1 expression and MyD88-IRAK complex formation
    • Li, C. H., J. H. Wang, and H. P. Redmond. 2006. Bacterial lipoprotein-induced self-tolerance and cross-tolerance to LPS are associated with reduced IRAK-1 expression and MyD88-IRAK complex formation. J. Leukocyte Biol. 79: 867-875.
    • (2006) J. Leukocyte Biol. , vol.79 , pp. 867-875
    • Li, C.H.1    Wang, J.H.2    Redmond, H.P.3
  • 30
    • 0037097519 scopus 로고    scopus 로고
    • Lipopolysaccharide- and lipoteichoic acid-induced tolerance and cross-tolerance: Distinct alterations in IL-1 receptor-associated kinase
    • Jacinto, R., T. Hartung, C. McCall, and L. Li. 2002. Lipopolysaccharide- and lipoteichoic acid-induced tolerance and cross-tolerance: distinct alterations in IL-1 receptor-associated kinase. J. Immunol. 168: 6136-6141.
    • (2002) J. Immunol. , vol.168 , pp. 6136-6141
    • Jacinto, R.1    Hartung, T.2    McCall, C.3    Li, L.4
  • 31
    • 0037218547 scopus 로고    scopus 로고
    • Induction of in vitro reprogramming by Toll-like receptor (TLR)2 and TLR4 agonists in murine macrophages: Effects of TLR "homotolerance" versus "heterotolerance" on NF-κB signaling pathway components
    • Dobrovolskaia, M. A., A. E. Medvedev, K. E. Thomas, N. Cuesta, V. Toshchakov, T. Ren, M. J. Cody, S. M. Michalek, N. R. Rice, and S. N. Vogel. 2003. Induction of in vitro reprogramming by Toll-like receptor (TLR)2 and TLR4 agonists in murine macrophages: effects of TLR "homotolerance" versus "heterotolerance" on NF-κB signaling pathway components. J. Immunol. 170: 508-519.
    • (2003) J. Immunol. , vol.170 , pp. 508-519
    • Dobrovolskaia, M.A.1    Medvedev, A.E.2    Thomas, K.E.3    Cuesta, N.4    Toshchakov, V.5    Ren, T.6    Cody, M.J.7    Michalek, S.M.8    Rice, N.R.9    Vogel, S.N.10
  • 35
    • 0035808774 scopus 로고    scopus 로고
    • Structure-function relationship of cytokine induction by lipoteichoic acid from Staphylococcus aureus
    • Morath, S., A. Geyer, and T. Hartung. 2001. Structure-function relationship of cytokine induction by lipoteichoic acid from Staphylococcus aureus. J. Exp. Med. 193: 393-397.
    • (2001) J. Exp. Med. , vol.193 , pp. 393-397
    • Morath, S.1    Geyer, A.2    Hartung, T.3
  • 39
    • 0033932493 scopus 로고    scopus 로고
    • Peptidoglycan and lipoteichoic acid from Staphylococcus aureus induce tumor necrosis factor α, interleukin 6 (IL-6), and IL-10 production in both T cells and monocytes in a human whole blood model
    • Wang, J. E., P. F. Jorgensen, M. Almlof, C. Thiemermann, S. J. Foster, A. O. Aasen, and R. Solberg. 2000. Peptidoglycan and lipoteichoic acid from Staphylococcus aureus induce tumor necrosis factor α, interleukin 6 (IL-6), and IL-10 production in both T cells and monocytes in a human whole blood model. Infect. Immun. 68: 3965-3970.
    • (2000) Infect. Immun. , vol.68 , pp. 3965-3970
    • Wang, J.E.1    Jorgensen, P.F.2    Almlof, M.3    Thiemermann, C.4    Foster, S.J.5    Aasen, A.O.6    Solberg, R.7
  • 42
    • 0037080024 scopus 로고    scopus 로고
    • Tissue expression of human Toll-like receptors and differential regulation of Toll-like receptor mRNAs in leukocytes in response to microbes, their products, and cytokines
    • Zarember, K. A., and P. J. Godowski. 2002. Tissue expression of human Toll-like receptors and differential regulation of Toll-like receptor mRNAs in leukocytes in response to microbes, their products, and cytokines. J. Immunol. 168: 554-561.
    • (2002) J. Immunol. , vol.168 , pp. 554-561
    • Zarember, K.A.1    Godowski, P.J.2
  • 43
    • 0141705297 scopus 로고    scopus 로고
    • Toll-like receptors stimulate human neutrophil function
    • Hayashi, F., T. K. Means, and A. D. Luster. 2003. Toll-like receptors stimulate human neutrophil function. Blood 102: 2660-2669.
    • (2003) Blood , vol.102 , pp. 2660-2669
    • Hayashi, F.1    Means, T.K.2    Luster, A.D.3
  • 44
    • 0036570169 scopus 로고    scopus 로고
    • Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides
    • Hornung, V., S. Rothenfusser, S. Britsch, A. Krug, B. Jahrsdorfer, T. Giese, S. Endres, and G. Hartmann. 2002. Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides. J. Immunol. 168: 4531-4537.
    • (2002) J. Immunol. , vol.168 , pp. 4531-4537
    • Hornung, V.1    Rothenfusser, S.2    Britsch, S.3    Krug, A.4    Jahrsdorfer, B.5    Giese, T.6    Endres, S.7    Hartmann, G.8
  • 46
    • 0035903288 scopus 로고    scopus 로고
    • Subsets of human dendritic cell precursors express different Toll-like receptors and respond to different microbial antigens
    • Kadowaki, N., S. Ho, S. Antonenko, R. W. Malefyt, R. A. Kastelein, F. Bazan, and Y. J. Liu. 2001. Subsets of human dendritic cell precursors express different Toll-like receptors and respond to different microbial antigens. J. Exp. Med. 194: 863-869.
    • (2001) J. Exp. Med. , vol.194 , pp. 863-869
    • Kadowaki, N.1    Ho, S.2    Antonenko, S.3    Malefyt, R.W.4    Kastelein, R.A.5    Bazan, F.6    Liu, Y.J.7
  • 47
    • 10244270620 scopus 로고    scopus 로고
    • p38 MAPK activation controls the TLR3-mediated up-regulation of cytotoxicity and cytokine production in human NK cells
    • Pisegna, S., G. Pirozzi, M. Piccoli, L. Frati, A. Santoni, and G. Palmieri. 2004. p38 MAPK activation controls the TLR3-mediated up-regulation of cytotoxicity and cytokine production in human NK cells. Blood 104: 4157-4164.
    • (2004) Blood , vol.104 , pp. 4157-4164
    • Pisegna, S.1    Pirozzi, G.2    Piccoli, M.3    Frati, L.4    Santoni, A.5    Palmieri, G.6
  • 48
    • 30744437150 scopus 로고    scopus 로고
    • Activation of TLR-9 induces IL-8 secretion through peroxynitrite signaling in human neutrophils
    • Jozsef, L., T. Khreiss, D. El Kebir, and J. G. Filep. 2006. Activation of TLR-9 induces IL-8 secretion through peroxynitrite signaling in human neutrophils. J. Immunol. 176: 1195-1202.
    • (2006) J. Immunol. , vol.176 , pp. 1195-1202
    • Jozsef, L.1    Khreiss, T.2    El Kebir, D.3    Filep, J.G.4
  • 49
    • 0014643535 scopus 로고
    • Mechanisms of endotoxin tolerance: V. Specificity of the early and late phases of pyrogenic tolerance
    • Greisman, S. E., E. J. Young, and F. A. Carozza, Jr. 1969. Mechanisms of endotoxin tolerance: V. Specificity of the early and late phases of pyrogenic tolerance. J. Immunol. 103: 1223-1236.
    • (1969) J. Immunol. , vol.103 , pp. 1223-1236
    • Greisman, S.E.1    Young, E.J.2    Carozza Jr., F.A.3
  • 50
    • 0036099755 scopus 로고    scopus 로고
    • Endotoxin tolerance-current concepts in historical perspective
    • Cross, A. S. 2002. Endotoxin tolerance-current concepts in historical perspective. J. Endotoxin Res. 8: 83-98.
    • (2002) J. Endotoxin Res. , vol.8 , pp. 83-98
    • Cross, A.S.1
  • 52
    • 0037320451 scopus 로고    scopus 로고
    • TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-β induction
    • Oshiumi, H., M. Matsumoto, K. Funami, T. Akazawa, and T. Seya. 2003. TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-β induction. Nat. Immunol. 4: 161-167.
    • (2003) Nat. Immunol. , vol.4 , pp. 161-167
    • Oshiumi, H.1    Matsumoto, M.2    Funami, K.3    Akazawa, T.4    Seya, T.5
  • 54
    • 0037114185 scopus 로고    scopus 로고
    • A novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-β promoter in the Toll-like receptor signaling
    • Yamamoto, M., S. Sato, K. Mori, K. Hoshino, O. Takeuchi, K. Takeda, and S. Akira. 2002. A novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-β promoter in the Toll-like receptor signaling. J. Immunol. 169: 6668-6672.
    • (2002) J. Immunol. , vol.169 , pp. 6668-6672
    • Yamamoto, M.1    Sato, S.2    Mori, K.3    Hoshino, K.4    Takeuchi, O.5    Takeda, K.6    Akira, S.7
  • 57
    • 34447505084 scopus 로고    scopus 로고
    • Toll-like receptors and type I interferons
    • Uematsu, S., and S. Akira. 2007. Toll-like receptors and type I interferons. J. Biol. Chem. 282: 15319-15323.
    • (2007) J. Biol. Chem. , vol.282 , pp. 15319-15323
    • Uematsu, S.1    Akira, S.2
  • 59
  • 60
  • 62
    • 40949103405 scopus 로고    scopus 로고
    • TRIM-ing down Tolls
    • Bowie, A. G. 2008. TRIM-ing down Tolls. Nat. Immunol. 9: 348-350.
    • (2008) Nat. Immunol. , vol.9 , pp. 348-350
    • Bowie, A.G.1
  • 64
    • 33846064294 scopus 로고    scopus 로고
    • Innate immune functions of plasmacytoid dendritic cells
    • Cao, W., and Y. J. Liu. 2007. Innate immune functions of plasmacytoid dendritic cells. Curr. Opin. Immunol. 19: 24-30.
    • (2007) Curr. Opin. Immunol. , vol.19 , pp. 24-30
    • Cao, W.1    Liu, Y.J.2
  • 65
    • 33644752743 scopus 로고    scopus 로고
    • Specialization, kinetics, and repertoire of type 1 interferon responses by human plasmacytoid predendritic cells
    • Ito, T., H. Kanzler, O. Duramad, W. Cao, and Y. J. Liu. 2006. Specialization, kinetics, and repertoire of type 1 interferon responses by human plasmacytoid predendritic cells. Blood 107: 2423-2431.
    • (2006) Blood , vol.107 , pp. 2423-2431
    • Ito, T.1    Kanzler, H.2    Duramad, O.3    Cao, W.4    Liu, Y.J.5
  • 66
    • 33644853807 scopus 로고    scopus 로고
    • A whole blood assay to assess peripheral blood dendritic cell function in response to Toll-like receptor stimulation
    • Ida, J. A., N. Shrestha, S. Desai, S. Pahwa, W. A. Hanekom, and P. A. Haslett. 2006. A whole blood assay to assess peripheral blood dendritic cell function in response to Toll-like receptor stimulation. J. Immunol. Methods 310: 86-99.
    • (2006) J. Immunol. Methods , vol.310 , pp. 86-99
    • Ida, J.A.1    Shrestha, N.2    Desai, S.3    Pahwa, S.4    Hanekom, W.A.5    Haslett, P.A.6
  • 67
    • 0037013830 scopus 로고    scopus 로고
    • Interferon-α and interleukin-12 are induced differentially by Toll-like receptor 7 ligands in human blood dendritic cell subsets
    • Ito, T., R. Amakawa, T. Kaisho, H. Hemmi, K. Tajima, K. Uehira, Y. Ozaki, H. Tomizawa, S. Akira, and S. Fukuhara. 2002. Interferon-α and interleukin-12 are induced differentially by Toll-like receptor 7 ligands in human blood dendritic cell subsets. J. Exp. Med. 195: 1507-1512.
    • (2002) J. Exp. Med. , vol.195 , pp. 1507-1512
    • Ito, T.1    Amakawa, R.2    Kaisho, T.3    Hemmi, H.4    Tajima, K.5    Uehira, K.6    Ozaki, Y.7    Tomizawa, H.8    Akira, S.9    Fukuhara, S.10
  • 68
    • 0035865228 scopus 로고    scopus 로고
    • - type 2 dendritic cell precursors and CD11c dendritic cells to produce type I IFN
    • - type 2 dendritic cell precursors and CD11c dendritic cells to produce type I IFN. J. Immunol. 166: 2291-2295.
    • (2001) J. Immunol. , vol.166 , pp. 2291-2295
    • Kadowaki, N.1    Antonenko, S.2    Liu, Y.J.3
  • 70
    • 0034146271 scopus 로고    scopus 로고
    • Endotoxin inducible transcription is repressed in endotoxin tolerant cells
    • Yoza, B. K., J. Y. Hu, S. L. Cousart, and C. E. McCall. 2000. Endotoxin inducible transcription is repressed in endotoxin tolerant cells. Shock 13: 236-243.
    • (2000) Shock , vol.13 , pp. 236-243
    • Yoza, B.K.1    Hu, J.Y.2    Cousart, S.L.3    McCall, C.E.4
  • 71
    • 34250823515 scopus 로고    scopus 로고
    • Gene-specific control of inflammation by TLR-induced chromatin modifications
    • Foster, S. L., D. C. Hargreaves, and R. Medzhitov. 2007. Gene-specific control of inflammation by TLR-induced chromatin modifications. Nature 447: 972-978.
    • (2007) Nature , vol.447 , pp. 972-978
    • Foster, S.L.1    Hargreaves, D.C.2    Medzhitov, R.3
  • 72
    • 21244481640 scopus 로고    scopus 로고
    • Endotoxin tolerance disrupts chromatin remodeling and NF-κB transactivation at the IL-1β promoter
    • Chan, C., L. Li, C. E. McCall, and B. K. Yoza. 2005. Endotoxin tolerance disrupts chromatin remodeling and NF-κB transactivation at the IL-1β promoter. J. Immunol. 175: 461-468.
    • (2005) J. Immunol. , vol.175 , pp. 461-468
    • Chan, C.1    Li, L.2    McCall, C.E.3    Yoza, B.K.4
  • 74
    • 33845508583 scopus 로고    scopus 로고
    • Endotoxin tolerance attenuates LPS-induced TLR4 mobilization to lipid rafts: A condition reversed by PKC activation
    • Cuschieri, J., J. Billigren, and R. V. Maier. 2006. Endotoxin tolerance attenuates LPS-induced TLR4 mobilization to lipid rafts: a condition reversed by PKC activation. J. Leukocyte Biol. 80: 1289-1297.
    • (2006) J. Leukocyte Biol. , vol.80 , pp. 1289-1297
    • Cuschieri, J.1    Billigren, J.2    Maier, R.V.3
  • 75
    • 41249084567 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of MyD88 adapter-like (Mal) is critical for signal transduction and blocked in endotoxin tolerance
    • Piao, W., C. Song, H. Chen, L. M. Wahl, K. A. Fitzgerald, L. A. O'Neill, and A. E. Medvedev. 2008. Tyrosine phosphorylation of MyD88 adapter-like (Mal) is critical for signal transduction and blocked in endotoxin tolerance. J. Biol. Chem. 283: 3109-3119.
    • (2008) J. Biol. Chem. , vol.283 , pp. 3109-3119
    • Piao, W.1    Song, C.2    Chen, H.3    Wahl, L.M.4    Fitzgerald, K.A.5    O'Neill, L.A.6    Medvedev, A.E.7
  • 76
    • 0036838930 scopus 로고    scopus 로고
    • Dysregulation of LPS-induced Toll-like receptor 4-MyD88 complex formation and IL-1 receptor-associated kinase 1 activation in endotoxin-tolerant cells
    • Medvedev, A. E., A. Lentschat, L. M. Wahl, D. T. Golenbock, and S. N. Vogel. 2002. Dysregulation of LPS-induced Toll-like receptor 4-MyD88 complex formation and IL-1 receptor-associated kinase 1 activation in endotoxin-tolerant cells. J. Immunol. 169: 5209-5216.
    • (2002) J. Immunol. , vol.169 , pp. 5209-5216
    • Medvedev, A.E.1    Lentschat, A.2    Wahl, L.M.3    Golenbock, D.T.4    Vogel, S.N.5
  • 78
    • 0033857751 scopus 로고    scopus 로고
    • Lipopolysaccharide-triggered desensitization of TNF-α mRNA expression involves lack of phosphorylation of IκBα in a murine macrophage-like cell line, P388D1
    • Fujihara, M., S. Wakamoto, T. Ito, M. Muroi, T. Suzuki, H. Ikeda, and K. Ikebuchi. 2000. Lipopolysaccharide-triggered desensitization of TNF-α mRNA expression involves lack of phosphorylation of IκBα in a murine macrophage-like cell line, P388D1. J. Leukocyte Biol. 68: 267-276.
    • (2000) J. Leukocyte Biol. , vol.68 , pp. 267-276
    • Fujihara, M.1    Wakamoto, S.2    Ito, T.3    Muroi, M.4    Suzuki, T.5    Ikeda, H.6    Ikebuchi, K.7
  • 79
    • 0034725584 scopus 로고    scopus 로고
    • Characterization of interleukin-1 receptor-associated kinase in normal and endotoxin-tolerant cells
    • Li, L., S. Cousart, J. Hu, and C. E. McCall. 2000. Characterization of interleukin-1 receptor-associated kinase in normal and endotoxin-tolerant cells. J. Biol. Chem. 275: 23340-23345.
    • (2000) J. Biol. Chem. , vol.275 , pp. 23340-23345
    • Li, L.1    Cousart, S.2    Hu, J.3    McCall, C.E.4
  • 80
    • 0034697145 scopus 로고    scopus 로고
    • mRNA and protein stability regulate the differential expression of pro- and anti-inflammatory genes in endotoxin-tolerant THP-1 cells
    • Learn, C. A., S. B. Mizel, and C. E. McCall. 2000. mRNA and protein stability regulate the differential expression of pro- and anti-inflammatory genes in endotoxin-tolerant THP-1 cells. J. Biol. Chem. 275: 12185-12193.
    • (2000) J. Biol. Chem. , vol.275 , pp. 12185-12193
    • Learn, C.A.1    Mizel, S.B.2    McCall, C.E.3
  • 81
    • 30044441094 scopus 로고    scopus 로고
    • Limiting inflammatory responses during activation of innate immunity
    • Han, J., and R. J. Ulevitch. 2005. Limiting inflammatory responses during activation of innate immunity. Nat. Immunol. 6: 1198-1205.
    • (2005) Nat. Immunol. , vol.6 , pp. 1198-1205
    • Han, J.1    Ulevitch, R.J.2
  • 82
    • 23744506255 scopus 로고    scopus 로고
    • Negative regulation of cytokine and TLR signalings by SOCS and others
    • Naka, T., M. Fujimoto, H. Tsutsui, and A. Yoshimura. 2005. Negative regulation of cytokine and TLR signalings by SOCS and others. Adv. Immunol. 87: 61-122.
    • (2005) Adv. Immunol. , vol.87 , pp. 61-122
    • Naka, T.1    Fujimoto, M.2    Tsutsui, H.3    Yoshimura, A.4
  • 84
    • 0034655280 scopus 로고    scopus 로고
    • IL-1 receptor-associated kinase modulates host responsiveness to endotoxin
    • Swantek, J. L., M. F. Tsen, M. H. Cobb, and J. A. Thomas. 2000. IL-1 receptor-associated kinase modulates host responsiveness to endotoxin. J. Immunol. 164: 4301-4306.
    • (2000) J. Immunol. , vol.164 , pp. 4301-4306
    • Swantek, J.L.1    Tsen, M.F.2    Cobb, M.H.3    Thomas, J.A.4
  • 88
    • 34249095729 scopus 로고    scopus 로고
    • Essential role of IRAK-4 protein and its kinase activity in Toll-like receptor-mediated immune responses but not in TCR signaling
    • Kawagoe, T., S. Sato, A. Jung, M. Yamamoto, K. Matsui, H. Kato, S. Uematsu, O. Takeuchi, and S. Akira. 2007. Essential role of IRAK-4 protein and its kinase activity in Toll-like receptor-mediated immune responses but not in TCR signaling. J. Exp. Med. 204: 1013-1024.
    • (2007) J. Exp. Med. , vol.204 , pp. 1013-1024
    • Kawagoe, T.1    Sato, S.2    Jung, A.3    Yamamoto, M.4    Matsui, K.5    Kato, H.6    Uematsu, S.7    Takeuchi, O.8    Akira, S.9
  • 89
    • 0242362818 scopus 로고    scopus 로고
    • Rapid up-regulation of IRAK-M expression following a second endotoxin challenge in human monocytes and in monocytes isolated from septic patients
    • Escoll, P., C. Del Fresno, L. Garcia, G. Valles, M. J. Lendinez, F. Arnalich, and E. Lopez-Collazo. 2003. Rapid up-regulation of IRAK-M expression following a second endotoxin challenge in human monocytes and in monocytes isolated from septic patients. Biochem. Biophys. Res. Commun. 311: 465-472.
    • (2003) Biochem. Biophys. Res. Commun. , vol.311 , pp. 465-472
    • Escoll, P.1    Del Fresno, C.2    Garcia, L.3    Valles, G.4    Lendinez, M.J.5    Arnalich, F.6    Lopez-Collazo, E.7


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