Synthesis of oxalamide and triazine derivatives as a novel class of hybrid 4-aminoquinoline with potent antiplasmodial activity

Bioorganic and Medicinal Chemistry

Volumn 17, Issue 17, 2009, Pages 6451-6462

  Sunduru, Naresh ^a   Sharma, Moni ^a   Srivastava, Kumkum ^a   Rajakumar, S ^a   Puri, S K ^a   Saxena, J K ^a   Chauhan, Prem M S ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

4 Aminoquinoline; Antimalarial; Oxalamide; Triazine

Indexed keywords

4 AMINOQUINOLINE DERIVATIVE; AMIDE; ANTIMALARIAL AGENT; CHLOROQUINE; N1 [3 (7 CHLOROQUINOLIN 4 YLAMINO)PROPYL] N2 [2 (DIMETHYLAMINO)ETHYL]OXALAMIDE; N2 [3 (7 CHLOROQUIN 4 YLAMINO)PROPYL] N4 (3 MORPHOLINOPROPYL) 6 (PIPERIDIN 1 YL) 1,3,5 TRIAZINE 2,4 DIAMINE; TRIAZINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIMALARIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG POTENCY; DRUG SCREENING; DRUG SELECTIVITY; DRUG SYNTHESIS; HYBRID; IC 50; IN VITRO STUDY; MALARIA; MALE; MOUSE; NONHUMAN; PARASITEMIA; PLASMODIUM FALCIPARUM; PLASMODIUM YOELII; STRUCTURE ACTIVITY RELATION;

AMIDES; AMINOQUINOLINES; ANIMALS; ANTIMALARIALS; CERCOPITHECUS AETHIOPS; HEMEPROTEINS; MALE; MICE; PLASMODIUM FALCIPARUM; PLASMODIUM YOELII; TRIAZINES; VERO CELLS;

PLASMODIUM FALCIPARUM; PLASMODIUM YOELII;

EID: 68649086911     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2009.05.075     Document Type: Article

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