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Volumn 13, Issue 15, 2005, Pages 4645-4650
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Synthesis of 2,4,6-trisubstituted pyrimidines as antimalarial agents
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Author keywords
Antimalarial; Dihydrofolate reductase; Pyrimidine
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Indexed keywords
(4 PHENYL) 6 PYRIDIN 4 YL 2 PYRROLIDIN 1 YLPYRIMIDINE;
2 PIPERIDIN 1 YL 4 PYRIDIN 4 YL 6 (2,4,5 TRIMETHOXYPHENYL)PYRIMIDINE;
2 PIPERIDIN 1 YL 4 PYRIDIN 4 YL 6 (3,4,5 TRIMETHOXYPHENYL)PYRIMIDINE;
2 PIPERIDIN 1 YL 4 PYRIDIN 4 YL 6 (4 TOLYLPYRIMIDINE) (3,4,5 TRIMETHOXYPHENYL)PYRIMIDINE;
4 (2,5 DIMETHOXYPHENYL) 2 PIPERIDIN 1 YL 6 PYRIDIN 4 YLPYRIMIDINE;
4 (2,5 DIMETHOXYPHENYL) 6 PYRIDIN 4 YL 2 PYRROLIDIN 1 YLPYRIMIDINE;
4 (3,4 DIMETHYLPHENYL) 2 PIPERIDIN 1 YL 6 PYRIDIN 4 YLPYRIMIDINE;
4 (3,4 DIMETHYLPHENYL) 6 PYRIDIN 4 YL 2 PYRROLIDIN 1 YLPYRIMIDINE;
4 (4 CHLOROPHENYL) 2 PIPERIDIN 1 YL 6 PYRIDIN 4 YLPYRIMIDINE;
4 (4 CHLOROPHENYL) 6 PYRIDIN 4 YL 2 PYRROLIDIN 1 YLPYRIMIDINE;
4 (4 METHOXYPHENYL) 2 PIPERIDIN 1 YL 6 PYRIDIN 4 YLPYRIMIDINE;
4 (4 METHOXYPHENYL) 6 PYRIDIN 4 YL 2 PYRROLIDIN 1 YLPYRIMIDINE;
4 (4 METHYLSULFANYLPHENYL) 2 PIPERIDIN 1 YL 6 PYRIDIN 4 YLPYRIMIDINE;
4 (4 METHYLSULFANYLPHENYL) 6 PYRIDIN 4 YL 2 PYRROLIDIN 1 YLPYRIMIDINE;
4 PHENYL 2 PIPERIDIN 1 YL 6 PYRIDIN 4 YLPYRIMIDINE;
4 PYRIDIN 4 YL 2 PYRROLIDIN 1 YL 6 (2,4,5 TRIMETHOXYPHENYL)PYRIMIDINE;
4 PYRIDIN 4 YL 2 PYRROLIDIN 1 YL 6 (3,4,5 TRIMETHOXYPHENYL)PYRIMIDINE;
4 PYRIDIN 4 YL 2 PYRROLIDIN 1 YL 6 (4 TOLYLPYRIMIDINE);
ANTIMALARIAL AGENT;
PYRIMETHAMINE;
PYRIMIDINE DERIVATIVE;
UNCLASSIFIED DRUG;
ANTIMALARIAL ACTIVITY;
ARTICLE;
CONTROLLED STUDY;
DRUG ACTIVITY;
DRUG SCREENING;
DRUG SYNTHESIS;
IN VITRO STUDY;
MINIMUM INHIBITORY CONCENTRATION;
NONHUMAN;
PLASMODIUM FALCIPARUM;
SUBSTITUTION REACTION;
ANIMALS;
ANTIMALARIALS;
MOLECULAR STRUCTURE;
PLASMODIUM FALCIPARUM;
PYRIMIDINES;
STRUCTURE-ACTIVITY RELATIONSHIP;
PLASMODIUM FALCIPARUM;
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EID: 20544450535
PISSN: 09680896
EISSN: None
Source Type: Journal
DOI: 10.1016/j.bmc.2005.04.061 Document Type: Article |
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Times cited : (147)
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References (27)
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