Substituted quinolinyl chalcones and quinolinyl pyrimidines as a new class of anti-infective agents

European Journal of Medicinal Chemistry

Volumn 44, Issue 5, 2009, Pages 2081-2091

  Sharma, Moni ^a   Chaturvedi, Vinita ^a   Manju, Y K ^a   Bhatnagar, Shalini ^a   Srivastava, Kumkum ^a   Puri, S K ^a   Chauhan, Prem M S ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

Chalcones; Malaria; Pyrimidines; Tuberculosis

Indexed keywords

1 [4 (7 CHLOROQUINOLIN 4 YLAMINO)PHENYL] 3 (2,3 DIMETHOXYPHENYL)PROP 2 EN 1 ONE; 1 [4 (7 CHLOROQUINOLIN 4 YLAMINO)PHENYL] 3 (2,3,4 TRIMETHOXYPHENYL)PROP 2 EN 1 ONE; 1 [4 (7 CHLOROQUINOLIN 4 YLAMINO)PHENYL] 3 (2,5 DIMETHOXYPHENYL)PROP 2 EN 1 ONE; 1 [4 (7 CHLOROQUINOLIN 4 YLAMINO)PHENYL] 3 (3,4,5 TRIMETHOXYPHENYL)PROP 2 EN 1 ONE; 1 [4 (7 CHLOROQUINOLIN 4 YLAMINO)PHENYL] 3 (4 ISOPROPYLPHENYL)PROP 2 EN 1 ONE; 1 [4 (7 CHLOROQUINOLIN 4 YLAMINO)PHENYL] 3 (4 METHOXYPHENYL)PROP 2 EN 1 ONE; 1 [4 (7 CHLOROQUINOLIN 4 YLAMINO)PHENYL] 3 (FURAN 2 YL)PROP 2 EN 1 ONE; 1 [4 (7 CHLOROQUINOLIN 4 YLAMINO)PHENYL] 3 (PYRIDIN 3 YL)PROP 2 EN 1 ONE; 1 [4 (7 CHLOROQUINOLIN 4 YLAMINO)PHENYL] 3 [4 (METHYLTHIO)PHENYL]PROP 2 EN 1 ONE; 1 [4 (7 CHLOROQUINOLIN 4 YLAMINO)PHENYL] 3 PHENYLPROP 2 EN 1 ONE; 1 [4 (7 CHLOROQUINOLIN 4 YLOXY)PHENYL] 3 (2,3 DIMETHOXYPHENYL)PROP 2 EN 1 ONE; 1 [4 (7 CHLOROQUINOLIN 4 YLOXY)PHENYL] 3 (2,3,4 TRIMETHOXYPHENYL)PROP 2 EN 1 ONE; 1 [4 (7 CHLOROQUINOLIN 4 YLOXY)PHENYL] 3 (2,5 DIMETHOXYPHENYL)PROP 2 EN 1 ONE; 1 [4 (7 CHLOROQUINOLIN 4 YLOXY)PHENYL] 3 (3,4,5 TRIMETHOXYPHENYL)PROP 2 EN 1 ONE; 1 [4 (7 CHLOROQUINOLIN 4 YLOXY)PHENYL] 3 (4 METHOXYPHENYL)PROP 2 EN 1 ONE; 1 [4 (7 CHLOROQUINOLIN 4 YLOXY)PHENYL] 3 (FURAN 2 YL)PROP 2 EN 1 ONE; 1 [4 (7 CHLOROQUINOLIN 4 YLOXY)PHENYL] 3 (PYRIDIN 3 YL)PROP 2 EN 1 ONE; 1 [4 (7 CHLOROQUINOLIN 4 YLOXY)PHENYL] 3 [4 (METHYLTHIO)PHENYL]PROP 2 EN 1 ONE; 1 [4 (7 CHLOROQUINOLIN 4 YLOXY)PHENYL] 3 PHENYLPROP 2 EN 1 ONE; 3 (2 CHLOROPHENYL) 1 [4 (7 CHLOROQUINOLIN 4 YLAMINO)PHENYL]PROP 2 EN 1 ONE; 3 (2 CHLOROPHENYL) 1 [4 (7 CHLOROQUINOLIN 4 YLOXY)PHENYL]PROP 2 EN 1 ONE; 3 (3 BROMOPHENYL) 1 [4 (7 CHLOROQUINOLIN 4 YLAMINO)PHENYL]PROP 2 EN 1 ONE; 3 (4 CHLOROPHENYL) 1 [4 (7 CHLOROQUINOLIN 4 YLAMINO)PHENYL]PROP 2 EN 1 ONE; 3 (4 CHLOROPHENYL) 1 [4 (7 CHLOROQUINOLIN 4 YLOXY)PHENYL]PROP 2 EN 1 ONE; ANTIINFECTIVE AGENT; CHALCONE DERIVATIVE; CHLOROQUINE; PYRAZINAMIDE; PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANIMAL CELL; ARTICLE; DRUG ACTIVITY; DRUG SCREENING; DRUG SYNTHESIS; IN VITRO STUDY; MINIMUM INHIBITORY CONCENTRATION; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PHYSICAL CHEMISTRY; PLASMODIUM FALCIPARUM; STRUCTURE ACTIVITY RELATION; VERO CELL;

ANIMALS; ANTI-INFECTIVE AGENTS; CHALCONES; MICROBIAL SENSITIVITY TESTS; MYCOBACTERIUM TUBERCULOSIS; PARASITIC SENSITIVITY TESTS; PLASMODIUM FALCIPARUM; PYRIMIDINES; QUINOLINES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 62549125426     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2008.10.011     Document Type: Article

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