Capillary electrophoresis of natural products: Current applications and recent advances

Planta Medica

Volumn 75, Issue 7, 2009, Pages 735-745

  Unger, Matthias ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

Capillary electrophoresis; Capillary electrophoresis mass spectrometry; Capillary zone electrophoresis; Field amplified sample injection; Micellar electrokinetic chromatography; Microemulsion electrokinetic chromatography; Sweeping

Indexed keywords

3,4 DICAFFEOYLQUINIC ACID; 6 METHOXYKAEMPFEROL 3 O GLUCOSIDE; 6 PRENYLNARINGENIN; 8 PRENYLNARINGENIN; ALKALOID DERIVATIVE; ANTHRAQUINONE DERIVATIVE; CHLOROGENIC ACID; COUMARIN DERIVATIVE; DITERPENE; ECDYSONE; FLAVONE DERIVATIVE; HISPIDULIN; HUMULON; HYPERFORIN; HYPERICIN; ISOCHLOROGENIC ACID; ISOFLAVONE DERIVATIVE; ISOQUERCITRIN; KAEMPFEROL 3 O GLUCOSIDE; LACTONE DERIVATIVE; NATURAL PRODUCT; PATULETIN 3 O GLUCOSIDE; POLYPHENOL DERIVATIVE; PROCYANIDIN DERIVATIVE; QUERCETIN 3 O GLUCURONIC ACID; SAPONIN DERIVATIVE; SESQUITERPENE LACTONE DERIVATIVE; TERPENE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG; XANTHONE DERIVATIVE; BIOLOGICAL PRODUCT;

ANALYTIC METHOD; CAPILLARY ELECTROCHROMATOGRAPHY; CAPILLARY ELECTROPHORESIS; CAPILLARY ZONE ELECTROPHORESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INSTRUMENT; MASS SPECTROMETRY; METABOLITE; MICELLAR ELECTROKINETIC CHROMATOGRAPHY; SEPARATION TECHNIQUE; SHORT SURVEY; CHEMISTRY; METHODOLOGY; REVIEW;

BIOLOGICAL PRODUCTS; ELECTROPHORESIS, CAPILLARY;

EID: 68349119328     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0029-1185453     Document Type: Short Survey

References (138)

1. Mikkers FEP, Everaerts FM, Verheggen ThPEM. High-performance zone electrophoresis. J Chromatogr 1979; 169: 11-20
2. Jorgenson JW, Lukacs KD. Zone electrophoresis in open-tubular glass capillaries. Anal Chem 1981; 53: 1298-1302
3. Jorgenson JW, Lukacs KD. Free-zone electrophoresis in glass capillaries. Clin Chem 1981; 27: 1551-1553
4. Altria KD, Elder D. Overview of the status and applications of capillary electrophoresis to the analysis of small molecules. J Chromatogr A 2004; 1023: 1-14 (Pubitemid 37494807)
5. Cheung RH, Marriot PJ, Small DM. CE methods applied to the analysis of micronutrients in foods. Electrophoresis 2007; 28: 3390-3413 (Pubitemid 47604700)
6. Huck CW, Stecher G, Scherz H, Bonn G. Analysis of drugs, natural and bioactive compounds containing phenolic groups by capillary electrophoresis coupled to mass spectrometry. Electrophoresis 2005; 26: 1319-1333 (Pubitemid 40645450)
7. Kostal V, Katzenmeyer J, Arriaga EA. Capillary electrophoresis in bio-analysis. Anal Chem 2008; 80: 4533-4550
8. Huo Y, Kok WT. Recent applications in CEC. Electrophoresis 2008; 29: 80-93
9. Kraly J, Fazal MA, Schoenherr RM, Bonn R, Harwood MM, Turner E, Jones M, Dovichi NJ. Bioanalytical applications of capillary electrophoresis. Anal Chem 2006; 78: 4097-4110
10. Issaq HJ. Capillary electrophoresis of natural products. Electrophoresis 1997; 18: 2438-2452
11. Issaq HJ. Capillary electrophoresis of natural products-II. Electrophoresis 1999; 20: 3190-3202
12. Suntornsuk L. Capillary electrophoresis of phytochemical substances. J Pharm Biomed Anal 2002; 27: 679-698
13. Bednár P, Papousková B, Müller L, Barták P, Stávek J, Pavlousek P, Lemr K. Utilization of capillary electrophoresis/mass spectrometry (CE/MSn) for the study of anthocyanin dyes. J Sep Sci 2005; 28: 1291-1299 (Pubitemid 41195338)
14. Petersson EV, Puerta A, Bergquist J, Turner C. Analysis of anthocyanins in red onion using capillary electrophoresis-time of flight-mass spectrometry. Electrophoresis 2008; 29: 2723-2730 (Pubitemid 351911900)
15. Seguera-Carretero A, Puertas-Mejía MA, Cortacero-Ramírez S, Beltrán R, Alonso-Villaverde C, Joven J, Dinelli G, Fernández- Gutiérrez A. Selective extraction, separation, and identification of anthocyanins from Hibiscus sabdariffa L. using solid phase extraction-capillary electrophoresis-mass spectrometry (time-of-flight/ion trap). Electrophoresis 2008; 29: 2852-2861
16. Unger M, Stöckigt D, Belder D, Stöckigt J. General approach for the analysis of various alkaloid classes using capillary electrophoresis and capillary electrophoresis-mass spectrometry. J Chromatogr A 1997; 767: 263-276 (Pubitemid 27199266)
17. Sturm S, Stuppner H. Analysis of isoquinoline alkaloids in medical plants by capillary electrophoresis-mass spectrometry. Electrophoresis 1998; 19: 3026-3032 (Pubitemid 28559937)
18. Unger M. Capillary zone electrophoresis of alkaloids - influence of structure on electrophoretic mobility. J Chromatogr A 1998; 807: 81-87 (Pubitemid 28258978)
19. Lechtenberg M, Quandt B, Nahrstedt A. Quantitative determination of curcuminoids in Curcuma rhizomes and rapid differentation of Curcuma domestica Val. and Curcuma xanthorrhiza Roxb. by capillary electrophoresis. Phytochem Anal 2004; 15: 152-158
20. Honda S, Iwase S, Makino A, Fujiwara S. Simultaneous determination of reducing monosaccharides by capillary zone electrophoresis as the borate complexes of N-2-pyridylglycamines. Anal Biochem 1989; 176: 72-77 (Pubitemid 19047030)
21. Schwaiger H, Oefner PJ, Huber C, Grill E, Bonn GK. Capillary zone electrophoresis and micellar electrokinetic chromatography of 4-aminobenzonitrile carbohydrate derivates. Electrophoresis 1994; 15: 941-952 (Pubitemid 24259510)
22. Zong YY, Che CT. Determination of strychnine and brucine by capillary zone electrophoresis. Planta Med 1995; 61: 456-458
23. Eeva M, Salo JP, Oksman-Caldentey KM. Determination of the main tropane alkaloids from transformed Hyoscyamus muticus plants by capillary zone electrophoresis. J Pharm Biomed Anal 1998; 16: 717-722
24. Unger M, Laug S, Holzgrabe U. Capillary zone electrophoresis as a tool for the quality control of goldenseal extracts. Electrophoresis 2005; 26: 2430-2436 (Pubitemid 40932750)
25. Koyama J, Morita I, Fujiyoshi H, Kobayashi N. Simultaneous determination of anthraquinones, their 8-beta-D-glucosides, and sennosides of Rhei Rhizoma by capillary electrophoresis. Chem Pharm Bull 2005; 53: 573-575 (Pubitemid 40740630)
26. Tian K, Zhang H, Chen X, Hu Z. Determination of five anthraquinones in medicinal plants by capillary zone electrophoresis with beta-cyclodextrin addition. J Chromatogr A 2006; 1123: 134-137
27. Sáenz-López R, Fernández-Zurbano P, Tena MT. Development and validation of a capillary zone electrophoresis method for the quantitative determination of anthocyanins in wine. J Chromatogr A 2003; 990: 247-258 (Pubitemid 36293881)
28. Ichiyanagi T, Kashiwada Y, Ikeshiro Y, Hatano Y, Shida Y, Horie Y, Matsugo S, Konishi T. Complete assignment of bilberry (Vaccinium myrtillus L.) anthocyanins separated by capillary zone electrophoresis. Chem Pharm Bull 2004; 51: 226-229
29. Vopli N, Maccari F, Linhardt RJ. Capillary electrophoresis of complex natural polysaccharides. Electrophoresis 2008; 29: 3095-3106
30. Arce L, Rios A, Valcárcel M. Determination of anti-carcinogenic polyphenols present in green tea using capillary electrophoresis coupled to a flow injection system. J Chromatogr A 1998; 827: 113-120 (Pubitemid 28543252)
31. Günaydin K, Erim FB. Determination of khellin and visnagin in Ammi visnaga fruits by capillary electrophoresis. J Chromatogr A 2002; 954: 291-294
32. Yue ME, Jiang TF, Liu X, Shi YP. Separation and determination of coumarins from Cacalia tangutica by capillary zone electrophoresis. Biomed Chromatogr 2005; 19: 250-254
33. Seitz U, Oefner PJ, Nathakarnkitkool S, Popp M, Bonn GK. Capillary electrophoretic analysis of flavonoids. Electrophoresis 1992; 13: 35-38
34. Quaglia MG, Bossù E, Donati E, Mazzanti G, Brandt A. Determination of silymarine in the extract from the dried silybum marianum fruits by high performance liquid chromatography and capillary electrophoresis. J Pharm Biomed Anal 1999; 19: 435-442 (Pubitemid 29073501)
35. Marchart E, Krenn L, Kopp B. Quantification of the flavonoid glycosides in Passiflora incarnata by capillary electrophoresis. Planta Med 2003; 69: 452-456
36. Bringmann G, Kajahn I, Neusüss C, Pelzing M, Laug S, Unger M, Holzgrabe U. Analysis of the glucosinolate pattern of Arabidopsis thaliana seeds by capillary zone electrophoresis coupled to electrospray ionization-mass spectrometry. Electrophoresis 2005; 26: 1513-1522
37. Trute A, Nahrstedt A. Identification and quantitative analysis of phenolic compounds from the dry extract of Hedera helix. Planta Med 1997; 63: 177-179 (Pubitemid 27196090)
38. Kreimeyer J, Petereit F, Nahrstedt A. Separations of flavan-3-ols and dimeric proanthocyanidins by capillary electrophoresis. Planta Med 1998; 64: 63-67 (Pubitemid 28060001)
39. Sáenz-López R, Fernández-Zurbano P, Tena MT. Analysis of aged red wine pigments by capillary zone electrophoresis. J Chromatogr A 2004; 1052: 191-197 (Pubitemid 39311953)
40. Emara S, Mohamed KM, Masujima T, Yamasaki K. Separation of naturally occurring triterpenoidal saponins by capillary zone electrophoresis. Biomed Chromatogr 2001; 15: 252-256 (Pubitemid 32655141)
41. Wu X, Gong S, Bo T, Liao Y, Liu H. Determination of dissociation constants of pharmacologically active xanthones by capillary zone electrophoresis with diode array detection. J Chromatogr A 2004; 1061: 217-223 (Pubitemid 39586750)
42. Li P, Li SP, Wang YT. Optimization of CZE for analysis of phytochemical bioactive compounds. Electrophoresis 2006; 27: 4808-4819 (Pubitemid 44932704)
43. Walbroehl Y, Jorgenson JW. On-column UVabsorption detector for open tubular capillary zone electrophoresis. J Chromatogr 1984; 315: 135-143
44. Bjornsdottir I, Tjornelund J, Jansen SH. Nonaqueous capillary electrophoresis - its applicability in the analysis of food, pharmaceuticals and biological fluids. Electrophoresis 1998; 19: 2179-2186 (Pubitemid 28451772)
45. Porras SP, Kenndler E. Are the asserted advantages of organic solvents in capillary electrophoresis real? A critical discussion. Electrophoresis 2005; 26: 3203-3220 (Pubitemid 43024482)
46. Wang T, Wei H, Li SF. Nonaqueous capillary zone electrophoresis for separation of free fatty acids with indirect fluorescence detection. Electrophoresis 1998; 19: 2187-2192 (Pubitemid 28451773)
47. Scriba GK. Non-aqueous capillary electrophoresis-mass spectrometry. J Chromatogr A 2007; 1159: 28-41
48. Barthe L, Ribet JP, Pélissou M, Degude MJ, Fahy J, Duflos A. Optimization of the separation of Vinca alkaloids by nonaqueous capillary electrophoresis. J Chromatogr A 2002; 968: 241-250
49. Li Y, He X, Qi S, Gao W, Chen X, Hu Z. Separation and determination of strychnine and brucine in Strychnos nux-vomica L. and its preparation by nonaqueous capillary electrophoresis. J Pharm Biomed Anal 2006; 41: 400-407
50. Liu Q, Liu Y, Li Y, Yao S. Nonaqueous capillary electrophoresis coupled with laser-induced native fluorescence detection for the analysis of berberine, palmatine, and jatrorrhizine in Chinese herbal medicines. J Sep Sci 2006; 29: 1268-1274 (Pubitemid 43950874)
51. Li Y, Qi S, Chen X, Hu Z. Separation and determination of the anthraquinones in Xanthophytum attopvensis Pierre by nonaqueous capillary electrophoresis. Talanta 2005; 65: 15-20
52. Li C, Chen A, Chen X, Ma X, Chen X, Hu Z. Non-aqueous capillary electrophoresis for separation and simultaneous determination of fraxin, esculin and esculetin in Cortex fraxini and its medicinal preparations. Biomed Chromatogr 2005; 19: 696-702
53. Qi S, Li Y, Wu S, Chen X, Hu Z. Novel nonaqueous capillary electrophoresis separation and determination of bioactive flavone derivates in Chinese herbs. J Sep Sci 2005; 28: 2180-2186 (Pubitemid 41700700)
54. Demianová Z, Sirén H, Kuldvee R, Riekkola ML. Nonaqueous capillary electrophoresis separation of polyphenolic compounds in wine using coated capillaries at high pH in methanol. Electrophoresis 2003; 24: 4264-4271 (Pubitemid 38094471)
55. Che AJ, Zhang JY, Li CH, Chen XF, Hu ZD, Chen XG. Separation and determination of active components in Radix Salviae miltiorrhizae and its medicinal preparations by nonaqueous capillary electrophoresis. J Sep Sci 2004; 27: 569-575
56. Qi S, Ding L, Tian K, Chen X, Hu Z. Novel and simple nonaqueous capillary electrophoresis separation and determination of bioactive triterpenes in Chinese herbs. J Pharm Biomed Anal 2006; 40: 35-41 (Pubitemid 43061213)
57. Jensen AG, Hansen SH. Separation of hypericins and hyperforins in extracts of Hypericum perforatum L. using non-aqueous capillary electrophoresis with reversed electroosmotic flow. J Pharm Biomed Anal 2002; 27: 167-176
58. Geiser L, Veuthey JL. Nonaqueous capillary electrophoresis in pharmaceutical analysis. Electrophoresis 2007; 28: 45-57 (Pubitemid 46178949)
59. Terabe S, Otsuka K, Ichikawa K, Tsuchiya A, Ando T. Electrokinetic separations with micellar solutions and open-tubular capillaries. Anal Chem 1984; 56: 111-113
60. Ganzera M, Egger C, Zidorn C, Stuppner H. Quantitative analysis of flavonoids and phenolic acids in Arnica montana L. by micellar electrokinetic capillary chromatography. Anal Chim Acta 2008; 614: 196-200
61. Kuo CH, Sun SW. Separation of bisbenzylisoquinoline alkaloids by micellar electrokinetic chromatography. Phytochem Anal 2002; 13: 63-68 (Pubitemid 34285517)
62. Yu L, Xu Y, Feng H, Li SF. Separation and determination of toxic pyrrolizidine alkaloids in traditional Chinese herbal medicines by micellar electrokinetic chromatography with organic modifier. Electrophoresis 2005; 26: 3397-3404 (Pubitemid 43024502)
63. Mateus L, Cherkaoui S, Christen P, Oksman-Caldentey KM. Simultaneous determination of scopolamine, hyoscyamine and littorine in plants and different hairy root clones of Hyoscyamus muticus by micellar electrokinetic chromatography. Phytochemistry 2000; 54: 517-523
64. Kuzuya H, Tamai I, Beppu H, Shimpo K, Chibara T. Determination of aloenin, barbaloin and isobarbaloin in aloe species by micellar electrokinetic chromatography. J Chromatogr B 2001; 752: 91-97 (Pubitemid 32141197)
65. Shang X, Yuan Z. Determination of hydroxyanthraquinoids in Rhubarb by cyclodextrin-modified micellar electrokinetic chromatography using a mixed micellar system of sodium dodecyl sulfate and sodium cholate. J Pharm Biomed Anal 2003; 31: 75-81 (Pubitemid 36120621)
66. Debusschère L, Demesmay C, Rocca JL, Lachatre G, Lofti H. Separation of cardiac glycosides by micellar electrokinetic chromatography and microemulsion electrokinetic chromatography. J Chromatogr A 1997; 779: 227-233 (Pubitemid 27402008)
67. Weiss DJ, Austria EJ, Anderton CR, Hompesch R, Jander A. Analysis of green tea extract supplements by micellar electrokinetic chromatography. J Chromatogr A 2006; 1117: 103-108 (Pubitemid 44275129)
68. Gotti R, Furlanetto S, Pinzauti S, Carvrini V. Analysis of catechins in Theobroma cacao beans by cyclodextrin-modified micellar electrokinetic chromatography. J Chromatogr A 2006; 1112: 345-352
69. Wang SF, Ju Y, Chen XG, Hu ZD. Separation and determination of coumarins in the root bark of three citrus plants by micellar electrokinetic capillary chromatography. Planta Med 2003; 69: 483-486 (Pubitemid 36774198)
70. Wang S, Dai J, Chen X, Hu Z. Identification and determination of ecdysones and flavonoids in Serratula strangulata by micellar electrokinetic capillary chromatography. Planta Med 2002; 68: 1029-1033
71. Zhang Y, Chen J, Ma XM, Shi YP. Simultaneous determination of flavonoids in Ixeridium gracile by micellar electrokinetic chromatography. J Pharm Biomed Anal 2007; 45: 742-746
72. Pietta P, Bruno A, Mauri P, Rava A. Separation of flavonol-2-O-glycosides from Calendula officinalis and Sambucus nigra by high-performance liquid and micellar electrokinetic capillary chromatography. J Chromatogr 1992; 593: 165-170
73. Song Y, Li P, Wang D, Cheng YY. Micellar electrokinetic chromatography for the quantitative analysis of flavonoids in the radix of Astragalus membranaceus var. mongholicus. Planta Med 2008; 74: 84-89
74. Karcher A, El Rassi Z. Capillary electrophoresis of glucosinolates and their degradation products. Electrophoresis 1999; 20: 3181-3189
75. Michaelsen S, Moller P, Sorensen H. Factors influencing the separation and quantitation of intact glucosinolates and desulphoglucosinolates by micellar electrokinetic capillary chromatography. J Chromatogr 1992; 608: 363-374
76. Baggett BR, Cooper JD, Hogan ET, Carper J, Paiva NL, Smith JT. Profiling isoflavonoids found in legume root extracts using capillary electrophoresis. Electrophoresis 2002; 23: 1642-1651 (Pubitemid 34727606)
77. Zhang Y, Chen J, Zhao L, Shi YP. Separation and determination of isoflavones in red clover by micellar electrokinetic capillary chromatography. Biomed Chromatogr 2007; 21: 987-992 (Pubitemid 47272334)
78. Cifuentes A, Bartolomé B, Gómez-Cardovés C. Fast determination of procyanidins and other phenolic compounds in food samples by micellar electrokinetic chromatography using acidic buffers. Electrophoresis 2001; 22: 1561-1567 (Pubitemid 32452104)
79. Herrero-Martínez JM, Ràflos C, Rosés M, Bosch E, Lozano C, Torres JL. Micellar electrokinetic chromatography estimation of size and composition of procyanidins after thiolysis with cysteine. Electrophoresis 2003; 24: 1404-1410 (Pubitemid 38088922)
80. Glöckl I, Veit M, Blaschke G. Determination of ginsenosides from Panax ginseng using micellar electrokinetic chromatography. Planta Med 2002; 68: 158-161
81. Petriska I, Polásek M, Sladkovský R. Assay of terpene alcohols in pharmacopoeial essential oils by micellar electrokinetic capillary chromatography (MEKC). Pharmazie 2006; 61: 989-993 (Pubitemid 46031890)
82. Dubber MJ, Kanfer I. Application of reverse-flow micellar electrokinetic chromatography for the simultaneous determination of flavonols and terpene trilactones in Ginkgo biloba dosage forms. J Chromatogr A 2006; 1122: 266-274 (Pubitemid 44041378)
83. Huie CW. Recent applications of microemulsion electrokinetic chromatography. Electrophoresis 2006; 27: 60-75
84. Pomponio R, Gotti R, Luppi B, Cavrini V. Microemulsion electrokinetic chromatography for the analysis of green tea catechins: effect of the cosurfactant on the separation selectivity. Electrophoresis 2003; 24: 1658-1667 (Pubitemid 38088951)
85. Huang HY, Lien WC, Chiu CW. Comparison of microemulsion electrokinetic chromatography and micellar electrokinetic chromatography methods for the analysis of phenolic compounds. J Sep Sci 2005; 28: 973-981 (Pubitemid 40909102)
86. Vanhoenacker G, Rong H, De Keukeleire D, Baeyens W, Van DerWeken G, Sandra P. Simultaneous analysis of hop acids and prenylated flavanones by microemulsion electrokinetic chromatography with diode array detection. Biomed Chromatogr 2000; 14: 34-36 (Pubitemid 30088489)
87. Aiken JH, Huie CW. Use of a microemulsion system to incorporate a lipophilic chiral selector in electrokinetic capillary chromatography. Chromatographia 1993; 35: 448-503
88. Sun SW, Yeh PC. Analysis of rhubarb anthraquinones and bianthrones by microemulsion electrokinetic chromatography. J Pharm Biomed Anal 2005; 36: 995-1001
89. Zhang J, Xie J, Liu J, Tian J, Chen X, Hu Z. Microemulsion electrokinetic chromatography with laser-induced fluorescence detection for sensitive determination of ephedrine and pseudoephedrine. Electrophoresis 2004; 25: 74-79 (Pubitemid 38196127)
90. Wenhua G, Yaowen C, Yegao Y, Xingguo C, Zhide H. Separation and determination of two sesquiterpene lactones in Radix inulae and Liuwei Anxian San by microemulsion electrokinetic chromatography. Biomed Chromatogr 2004; 18: 826-832 (Pubitemid 40089854)
91. Bo T, Yang X, Li KA, Xu L, Liu H. Comparison of micellar electrokinetic chromatography and microemulsion electrokinetic chromatography for separation of pharmacologically active xanthones from Securidaca inappendiculata. J Sep Sci 2003; 26: 133-136 (Pubitemid 36253760)
92. Scherz H, Huck CW, Bonn GK. CEC and EKC of natural compounds. Electrophoresis 2007; 28: 1645-1657
93. Lai EP, Dabek-Zlotorzynska E. Separation of theophylline, caffeine and related drugs by normal-phase capillary electrochromatography. Electrophoresis 1999; 20: 2366-2372 (Pubitemid 29422694)
94. Li Y, Liu H, Ji X, Li J. Optimized separation of pharmacologically active anthraquinones in Rhubarb by capillary electrochromatography. Electrophoresis 2000; 21: 3109-3115
95. Ganzera M, Stöggl WM, Bonn GK, Khan IA, Stuppner H. Capillary electrochromatography of boswellic acids in Boswellia serrata Roxb. J Sep Sci 2003; 26: 1383-1388
96. Lurie IS, Meyers RP, Conver TS. Capillary electrochromatography of cannabinoids. Anal Chem 1998; 70: 3255-3260
97. Desiderio C, De Rossi A, Sinibaldi M. Analysis of flavanone-7-O- glycosides in citrus juices by short-end capillary electrochromatography. J Chromatogr A 2005; 1081: 99-104 (Pubitemid 40799237)
98. Starkey JA, Mechref Y, Byun CK, Steinmetz R, Fuqua JS, Pescovitz OH, Novotny MV. Determination of trace isoflavone phytoestrogens in biological materials by capillary electrochromatography. Anal Chem 2002; 71: 5998-6005 (Pubitemid 35423906)
99. Abidi SL. Capillary electrochromatography of sterols and related steryl esters derived from vegetable oils. J Chromatogr A 2004; 1059: 199-208
100. Cherkaoui S, Cahours X, Veuthey JL. Analysis of selected withanolides in plant extracts by capillary electrochromatography and microemulsion electrokinetic chromatography. Electrophoresis 2003; 24: 336-342 (Pubitemid 36267171)
101. Wätzig H, Degenhardt M, Kunkel A. Strategies for capillary electrophoresis: method development and validation for pharmaceutical and biological applications. Electrophoresis 1998; 19: 2695-2752 (Pubitemid 28559901)
102. Lloyd DK, Wätzig H. Sodium dodecyl sulfate solution is an effective between- run rinse for capillary electrophoresis of samples in biological matrices. J Chromatogr B 1995; 663: 400-405
103. Wu N, Clausen AM. Fundamental and practical aspects of ultrahigh pressure liquid chromatography for fast separations. J Sep Sci 2007; 30: 1167-1182 (Pubitemid 46900063)
104. Hemström P, Irgum K. Hydrophilic interaction chromatography. J Sep Sci 2006; 29: 1784-1821
105. Dräger B. Analysis of tropane related alkaloids. J Chromatogr A 2002; 978: 1-35
106. Orlandini S, Giannini I, Pinzauti S, Furlanetto S. Multivariate optimisation and validation of a capillary electrophoresis method for the analysis of resveratrol in a nutraceutical. Talanta 2008; 74: 570-577
107. Olivares JA, Nguyen NT, Yonker CR, Smith RD. On-line mass spectrometric detection for capillary zone electrophoresis. Anal Chem 1987; 59: 1230-1232
108. Smith RD, Barinaga CJ, Udseth HR. Improved electrospray ionization interface for capillary zone electrophoresis-mass spectrometry. Anal Chem 1988; 60: 1948-1952
109. Banks JF. Recent advances in capillary electrophoresis/electrospray/ mass spectrometry. Electrophoresis 1997; 18: 2255-2266 (Pubitemid 28020586)
110. Hsieh FY, Cai J, Henion J. Determination of trace impurities of peptides and alkaloids by capillary electrophoresis-ion spray mass spectrometry. J Chromatogr A 1994; 679: 206-211 (Pubitemid 24283182)
111. Henion JD, Mordehai AV, Cai J. Quantitative capillary electrophoresis ion spray mass spectrometry on a benchtop ion trap for the determination of isoquinoline alkaloids. Anal Chem 1994; 66: 2103-2109 (Pubitemid 24238598)
112. Unger M, Stöckigt D, Belder D, Stöckigt J. Alkaloid determination in crude extracts from cortex quebracho and opium applying capillary electrophoresis and capillary electrophoresis-mass spectrometry coupling. Pharmazie 1997; 52: 691-695 (Pubitemid 28066260)
113. Stöckigt D, Unger M, Belder D, Stöckigt J. Analysis of Rauwolfia alkaloids employing capillary electrophoresis-mass spectrometry. Nat Prod Lett 1997; 9: 265-272
114. Sturm S, Seger C, Stuppner H. Analysis of Central European Corydalis species by nonaqueous capillary electrophoresis-electrospray ion trap mass spectrometry. J Chromatogr A 2007; 1159: 42-50
115. Bianco G, Schmitt-Kopplin P, De Benedetto G, Kettrup A, Cataldi TR. Determination of glycoalkaloids and relative aglycones by nonaqueous capillary electrophoresis coupled with electrospray ionization-ion trap mass spectrometry. Electrophoresis 2002; 23: 2904-2912
116. Unger M, Dreyer M, Specker S, Laug S, Pelzing M, Neusüss C, Holzgrabe U, Bringmann G. Analytical characterisation of crude extracts from an African Ancistrocladus species using high-performance liquid chromatography and capillary electrophoresis coupled to ion trap mass spectrometry. Phytochem Anal 2004; 15: 21-26
117. Wang S, Qu H, Cheng Y. NACE-ESI-MS combined with on-line concentration for high-sensitivity analysis of quinolizidine alkaloids. Electrophoresis 2007; 28: 1399-1406 (Pubitemid 46723212)
118. Arráez-Román D, Zurek G, Bässmann C, Segura-Carretero A, Fernández-Gutiérrez A. Characterisation of Atropa belladonna L. compounds by capillary electrophoresis-electrospray ionization-time of flight-mass spectrometry and capillary electrophoresis-electrospray ionization-ion trap-mass spectrometry. Electrophoresis 2008; 29: 2112-2116
119. Simó C, Barbas C, Cifuentes A. Capillary electrophoresis-mass spectrometry in food analysis. Electrophoresis 2005; 26: 1306-1318 (Pubitemid 40645449)
120. Vanhoenacker G, DeVilliers A, Lazou K, DeKeukeleire D, Sandra P. Comparison of high-performance liquid chromatography - mass spectroscopy and capillary electrophoresis - mass spectroscopy for the analysis of phenolic compounds in diethyl ether extracts of red wines. Chromatographia 2001; 54: 309-315 (Pubitemid 32911581)
121. Rodat A, Gavard P, Couderc F. Improving detection in capillary electrophoresis with laser induced fluorescence via a bubble cell capillary and laser power adjustment. Biomed Chromatogr 2009; 23: 42-47
122. Driedger DR, LeBlanc RJ, LeBlanc EL, Sporns P. A capillary electrophoresis laser-induced fluorescence method for analysis of potato glycoalkaloids based on a solution-phase immunoassay. 2. Performance evaluation. J Agric Food Chem 2000; 48: 4079-4082 (Pubitemid 30736362)
123. Zhang ZL, Liu X, Li DF, Lu YT. Determination of jasmonic acid in bark extracts from Hevea brasiliensis by capillary electrophoresis with laser-induced fluorescence detection. Anal Bioanal Chem 2005; 382: 1616-1619
124. Wang W, Tang J, Wang S, Zhou L, Hu Z. Method development for the determination of coumarin compounds by capillary electrophoresis with indirect laser-induced fluorescence detection. J Chromatogr A 2007; 1148: 108-114 (Pubitemid 46498862)
125. Geng CH, Wang WY, Lin M, Ye JN. Determination of flavonoids in Plumula nelumbini by micellar electrokinetic capillary electrophoresis with electrochemical detection. J Capill Electrophor Microchip Technol 2007; 10: 57-61
126. Yu LS, Xu XQ, Huang L, Ling JM, Chen GN. Separation and determination of flavonoids using microemulsion EKC with electrochemical detection. Electrophoresis 2008; 29: 726-733 (Pubitemid 351266762)
127. Simpson Jr SL, Quirino JP, Terabe S. On-line sample pre-concentration in capillary electrophoresis. Fundamentals and applications. J Chromatogr A 2008; 1184; 504-541 (Pubitemid 351296225)
128. Zhu J, Yu K, Chen X, Hu Z. Comparison of two sample pre-concentration strategies for the sensitivity enhancement of flavonoids found in Chinese herbal medicine in micellar electrokinetic chromatography with UV detection. J Chromatogr A 2007; 1166: 191-200 (Pubitemid 47361170)
129. Yu L, Xu X, Huang L, Lin J, Chen G. Microemulsion electrokinetic chromatography coupling with field amplified sample injection and electroosmotic flow suppressant for analysis of some quinolizidine alkaloids. J Chromatogr A 2008; 1198: 220-225
130. Unger M, Stöckigt J. Improved detection of alkaloids in crude extracts applying capillary electrophoresis with field amplified sample injection. J Chromatogr A 1997; 791: 323-331 (Pubitemid 28064801)
131. Petr J, Vitkocvá K, Ranc V, Znaleziona J, Maier V, Knob R, Sevcik J. Determination of some phenolic acids in Majorana hortensis by capillary electrophoresis with online electrokinetic pre-concentration. J Agric Food Chem 2008; 56: 3940-3944
132. Quirino JP, Otsuka K, Terabe S. On-line concentration of neutral analytes for micellar electrokinetic chromatography VI. Stacking using reverse migrating micelles and a water plug. J Chromatogr B 1998; 714: 29-38 (Pubitemid 29034596)
133. Quirino JP, Terabe S. Exceeding 5000-fold concentration of dilute analytes in micellar electrokinetic chromatography. Science 1998; 282: 465-468 (Pubitemid 28483671)
134. Huang HY, Hsieh SH. Analyses of tobacco alkaloids by cation-selective exhaustive injection sweeping microemulsion electrokinetic chromatography. J Chromatogr A 2007; 1164: 313-319
135. Huang HY, Huang IY, Liang HH, Lee S. Sample stacking for the analysis of catechins by microemulsion EKC. Electrophoresis 2007; 28: 1735-1743 (Pubitemid 46909728)
136. Huang HY, Lien WC, Huang IY. Anion-selective exhaustive injection-sweeping microemulsion electrokinetic chromatography. Electrophoresis 2006; 27: 3202-3209 (Pubitemid 44336006)
137. Hsieh MC, Lin CH. On-line identification of trans-resveratrol in red wine using a sweeping technique combined with capillary electrophoresis/77 K fluorescence spectroscopy. Electrophoresis 2004; 25: 677-682
138. Zhou M, Ma YJ, Ren XN, Zhou XY, Li L, Chen H. Determination of sinomenine in Sinomenium acutum by capillary electrophoresis with electrochemiluminescence detection. Anal Chim Acta 2007; 587: 104-109