Separation and determination of toxic pyrrolizidine alkaloids in traditional Chinese herbal medicines by micellar electrokinetic chromatography with organic modifier

Electrophoresis

Volumn 26, Issue 17, 2005, Pages 3397-3404

  Yu, Lijun ^a   Xu, Yan ^a   Feng, Huatao ^a   Li, Sam Fong Yau ^a,b  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b Ayer Rajah Industrial Estate   (Singapore)

Author keywords

Chinese herbal medicine; Kuan donghua; Micellar electrokinetic chromatography; Pyrrolizidine alkaloids; Qian liguang

Indexed keywords

ELECTRODYNAMICS; LIQUID CHROMATOGRAPHY; MEDICINE; METABOLITES; PLANT EXTRACTS;

CALIBRATION CURVES; CHINESE HERBAL MEDICINES; KUAN DONGHUA; MICELLAR ELECTROKINETIC CHROMATOGRAPHY; ORGANIC MODIFIER; PYRROLIZIDINE ALKALOID; QIAN LIGUANG; SEPARATION CONDITION; SIMPLE++; TRADITIONAL CHINESE HERBAL MEDICINE;

ALKALOIDS;

BORIC ACID; CHINESE DRUG; DODECYL SULFATE SODIUM; KUAN DONGHUA; METHANOL; PYRROLIZIDINE ALKALOID; QUIAN LIGUANG; RETRORSINE; SENECIONINE; SENECIPHYLLINE; UNCLASSIFIED DRUG; BUFFER; HERBACEOUS AGENT; ORGANIC COMPOUND;

ARTICLE; DRUG DETERMINATION; DRUG ISOLATION; DRUG STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTERMETHOD COMPARISON; MICELLAR ELECTROKINETIC CHROMATOGRAPHY; QUALITY CONTROL; QUANTITATIVE ANALYSIS; REPRODUCIBILITY; SENSITIVITY ANALYSIS; STRUCTURE ANALYSIS; CALIBRATION; CHEMISTRY; ISOLATION AND PURIFICATION; METHODOLOGY; SENSITIVITY AND SPECIFICITY;

BUFFERS; CALIBRATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, MICELLAR ELECTROKINETIC CAPILLARY; DRUGS, CHINESE HERBAL; METHANOL; ORGANIC CHEMICALS; PYRROLIZIDINE ALKALOIDS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SODIUM DODECYL SULFATE;

EID: 27244455745     PISSN: 01730835     EISSN: None     Source Type: Journal    
DOI: 10.1002/elps.200500233     Document Type: Article

References (30)

1. Pyrrolizidine Alkaloids, World Health Organization, Geneva 1988.
2. Garland, T., Barr, A. C., Toxic Plants and Other Natural Toxicants, CAB International, New York 1998.
3. Fu, P. P., Yang, Y. C., Xia, Q. S., Chou, M. W., Cui, Y. Y., Lin, G., J. Food Drug Anal. 2002, 10, 198-211.
4. Lebada, R., Schreier, A., Scherz, S., Resch, C., Krenn, L., Kopp, B., Phytochem. Anal. 2000, 11, 366-369.
5. Su, J., Traditional Chinese Dictionary, New Faculty of Medicine, Shanghai Science and technology, Shanghai 1979.
6. Gocan, S., Cimpan, G., J. Liq. Chromatogr. 2004, 27, 1377-1411.
7. Stelljes, M. E., Kelley, R. B., Molyneux, R. J., Seiber, J. N., J. Nat. Prod. 1991, 54, 759-773.
8. Dobler, S., Haberer, W., Witte, L., Hartmann, T., J. Chem. Ecol. 2000, 26, 1281-1298.
9. Trigo, J. R., Leal, I. R., Matzenbacher, N. I., Lewinsohn, T. M., Biochem. Syst. Ecol. 2003, 31, 1011-1022.
10. Hosch, G., Wiedenfeld, H., Dingermann, T., Roder, E., Phytochem. Anal. 1996, 7, 284-288.
11. Ndjoko, K., Wolfender, J. L., Roder, E., Hostettmann, K., Planta Med. 1999, 65, 562-566.
12. Crews, C., Startin, J. R., Clarke, P. A., Food Addit. Contam. 1997, 14, 419-428.
13. Mroczek, T., Baj, S., Chrobok, A., Glowniak, K., Biomed. Chromatogr. 2004, 18, 745-751.
14. Hendriks, H., Huizing, H. J., Bruins, A. P., J. Chromatogr. 1988, 428, 352-356.
15. Feng, H. T., Li, F. Y. S., J. Chromatogr. A 2002, 973, 243-247.
16. Li, Y. Q., Qi, S. D., Chen, X. G., Hu, Z. D., Electrophoresis 2004, 25, 3003-3009.
17. Marsh, A., Clark, B. J., Altria, K. D., Electrophoresis 2004, 25, 1270-1278.
18. Li, Y. Q., Cui, S. Y., Cheng, Y. Q., Chen, X. G., Hu, Z. D., Anal. Chim. Acta 2004, 508, 17-22.
19. Yu, Y. Q., Ding, P. L., Chen, D. F., Anal. Chim. Acta 2004, 523, 15-20.
20. Kreft, S., Zel, J., Pukl, M., Umek, A., Strukelj, B., Phytochem. Anal. 2000, 11, 37-40.
21. Gong, S. X., Su, X. D., Bo, T., Zhang, X., Liu, H. W., Li, K. A., J. Sep. Sci. 2003, 26, 549-554.
22. Reddy, M. M., Suresh, V., Jayashanker, G., Rao, B. S., Sarin, R. K., Electrophoresis 2003, 24, 1437-1441.
23. Mateus, L., Cherkaoui, S., Christen, P., Oksman-Caldentey, K. M., Phytochemistry 2000, 54, 517-523.
24. Koyama, J., Toyokuni, I., Kino, A., Tagahara, K., Phytochem. Anal. 1999, 10, 175-180.
25. Lebada, R., Schreier, A., Scherz, S., Resch, C., Krenn, L., Kopp, B., Phytochem. Anal. 2000, 11, 366-369.
26. Kim, J. B., Terabe, S., J. Pharmaceut. Biomed. 2003, 30, 1625-1643.
27. Otsuka, K., Terabe, S., J. Chromatogr. A 2000, 875, 163-178.
28. Quirino, J. P., Terabe, S., Science 1998, 282, 465-468.
29. Weston, A., Brown, P. R., HPLC and CE Principles and Practice, Academic Press, San Diego, CA 1997, pp. 134-183.
30. Parvez, H., Caudy, P., Parvez, S., Roland-Gosselin, P., Capillary Electrophoresis in Biotechnology and Environmental Analysis, VSP BV, The Netherlands 1997, pp. 201-244.