Mechanisms underlying enhanced vasorelaxant response to protease-activated receptor 2-activating peptide in type 2 diabetic Goto-Kakizaki rat mesenteric artery

Peptides

Volumn 30, Issue 9, 2009, Pages 1729-1734

  Matsumoto, Takayuki ^a   Ishida, Keiko ^a   Taguchi, Kumiko ^a   Kobayashi, Tsuneo ^a   Kamata, Katsuo ^a  

^a HOSHI UNIVERSITY   (Japan)

Author keywords

Endothelium dependent relaxation; GK rat; Mesenteric artery; NO; PAR2; Type 2 diabetes

Indexed keywords

ACETYLCHOLINE; BLOOD CLOTTING FACTOR 10A; G PROTEIN COUPLED RECEPTOR; INDOMETACIN; N(G) NITROARGININE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; PROTEINASE; PROTEINASE ACTIVATED RECEPTOR 2; PROTEINASE ACTIVATED RECEPTOR 2 ACTIVATING PEPTIDE; SYNTHETIC PEPTIDE; TRYPSIN; TRYPTASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD VESSEL REACTIVITY; CONTROLLED STUDY; DIABETIC ANGIOPATHY; ENZYME ACTIVATION; GOTO KAKIZAKI RAT; MALE; MESENTERIC ARTERY; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; STRAIN DIFFERENCE; VASCULAR ENDOTHELIUM; VASODILATATION; WISTAR RAT;

ACETYLCHOLINE; ANIMALS; CYCLOOXYGENASE INHIBITORS; DIABETES MELLITUS, TYPE 2; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; INDOMETHACIN; MALE; MESENTERIC ARTERIES; NITRATES; NITRIC OXIDE; NITRITES; NITROARGININE; OLIGOPEPTIDES; PHENYLEPHRINE; RATS; RATS, INBRED STRAINS; RATS, WISTAR; RECEPTOR, PAR-2; VASOCONSTRICTION; VASODILATION;

RATTUS; RATTUS NORVEGICUS;

EID: 67849135872     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.peptides.2009.06.014     Document Type: Article

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