-
1
-
-
49449088451
-
Diabetes data & trends
-
CDC Center for Disease Control and Prevention, United States, Available at:, Accessed February 9, 2008
-
(CDC) Center for Disease Control and Prevention. Diabetes data & trends. Number (in millions) of persons with diagnosed diabetes, United States, 1980-2005. Available at: http://www.cdc.gov/diabetes/statistics/prev/national/ figpersons.htm. Accessed February 9, 2008.
-
(1980)
Number (in millions) of persons with diagnosed diabetes
-
-
-
2
-
-
49449087876
-
-
CDC Center for Disease Control and Prevention, Available at:, Accessed February 9, 2008
-
(CDC) Center for Disease Control and Prevention. Diabetes data & trends. Overweight and obesity. U.S. Obesity Trends 1985-2006. Available at: http://www.cdc.gov/nccdphp/dnpa/obesity/trend/maps/. Accessed February 9, 2008.
-
Diabetes data & trends. Overweight and obesity. U.S. Obesity Trends 1985-2006
-
-
-
3
-
-
2342466734
-
Global prevalence of diabetes: Estimates for the year 2000 and projections for 2030
-
Wild S, Roglic G, Green A, Sicree R, King H. Global prevalence of diabetes: Estimates for the year 2000 and projections for 2030. Diabetes Care 2004;27:1047-1053.
-
(2004)
Diabetes Care
, vol.27
, pp. 1047-1053
-
-
Wild, S.1
Roglic, G.2
Green, A.3
Sicree, R.4
King, H.5
-
4
-
-
0035753516
-
The relationship between periodontal diseases and diabetes: An overview
-
Soskolne WA, Klinger A. The relationship between periodontal diseases and diabetes: An overview. Ann Periodontol 2001;6:91-98.
-
(2001)
Ann Periodontol
, vol.6
, pp. 91-98
-
-
Soskolne, W.A.1
Klinger, A.2
-
5
-
-
49449083437
-
-
CDC Center for Disease Control and Prevention, United States, General information. Available at:, Accessed February 9, 2008
-
(CDC) Center for Disease Control and Prevention. National diabetes fact sheet. United States, 2005 General information. Available at: http://apps.nccd.cdc.gov/DDTSTRS/template/ndfs_2005.pdf. Accessed February 9, 2008.
-
(2005)
-
-
-
6
-
-
6444241336
-
Epidemiology of childhood type 2 diabetes in the developing world
-
Singh R, Shaw J, Zimmet P. Epidemiology of childhood type 2 diabetes in the developing world. Pediatr Diabetes 2004;5:154-168.
-
(2004)
Pediatr Diabetes
, vol.5
, pp. 154-168
-
-
Singh, R.1
Shaw, J.2
Zimmet, P.3
-
7
-
-
7444228518
-
Elevated C-reactive protein levels do not correspond to autoimmunity in type 1 diabetes
-
Treszl A, Szereday L, Doria A, King GL, Orban T. Elevated C-reactive protein levels do not correspond to autoimmunity in type 1 diabetes. Diabetes Care 2004;27:2769-2770.
-
(2004)
Diabetes Care
, vol.27
, pp. 2769-2770
-
-
Treszl, A.1
Szereday, L.2
Doria, A.3
King, G.L.4
Orban, T.5
-
8
-
-
35748942911
-
Evidence of increased inflammation and microcirculatory abnormalities in patients with type 1 diabetes and their role in microvascular complications
-
Devaraj S, Cheung AT, Jialal I, et al. Evidence of increased inflammation and microcirculatory abnormalities in patients with type 1 diabetes and their role in microvascular complications. Diabetes 2007;56:2790-2796.
-
(2007)
Diabetes
, vol.56
, pp. 2790-2796
-
-
Devaraj, S.1
Cheung, A.T.2
Jialal, I.3
-
9
-
-
0036066485
-
High white blood cell count is associated with a worsening of insulin sensitivity and predicts the development of type 2 diabetes
-
Vozarova B, Weyer C, Lindsay RS, Pratley RE, Bogardus C, Tataranni PA. High white blood cell count is associated with a worsening of insulin sensitivity and predicts the development of type 2 diabetes. Diabetes 2002;51:455-461.
-
(2002)
Diabetes
, vol.51
, pp. 455-461
-
-
Vozarova, B.1
Weyer, C.2
Lindsay, R.S.3
Pratley, R.E.4
Bogardus, C.5
Tataranni, P.A.6
-
10
-
-
0035908632
-
C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus
-
Pradhan AD, Manson JE, Rifai N, Buring JE, Ridker PM. C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus. JAMA 2001;286:327-334.
-
(2001)
JAMA
, vol.286
, pp. 327-334
-
-
Pradhan, A.D.1
Manson, J.E.2
Rifai, N.3
Buring, J.E.4
Ridker, P.M.5
-
11
-
-
0037434058
-
C-reactive protein as a predictor for incident diabetes mellitus among middle-aged men: Results from the MONICA Augsburg cohort study, 1984-1998
-
Thorand B, Löwel H, Schneider A, et al. C-reactive protein as a predictor for incident diabetes mellitus among middle-aged men: Results from the MONICA Augsburg cohort study, 1984-1998. Arch Intern Med 2003;163:93-99.
-
(2003)
Arch Intern Med
, vol.163
, pp. 93-99
-
-
Thorand, B.1
Löwel, H.2
Schneider, A.3
-
12
-
-
0035381046
-
Obesity: A rational target for managing diabetes mellitus
-
Mooradian AD. Obesity: A rational target for managing diabetes mellitus. Growth Horm IGF Res 2001;11(Suppl. A):S79-S83.
-
(2001)
Growth Horm IGF Res
, vol.11
, Issue.SUPPL. A
-
-
Mooradian, A.D.1
-
14
-
-
33845866857
-
Inflammation and metabolic disorders
-
Hotamisligil GS. Inflammation and metabolic disorders. Nature 2006;444:860-867.
-
(2006)
Nature
, vol.444
, pp. 860-867
-
-
Hotamisligil, G.S.1
-
15
-
-
1642377274
-
Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes
-
Petersen KF, Dufour S, Befroy D, Garcia R, Shulman GI. Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes. N Engl J Med 2004;350:664-671.
-
(2004)
N Engl J Med
, vol.350
, pp. 664-671
-
-
Petersen, K.F.1
Dufour, S.2
Befroy, D.3
Garcia, R.4
Shulman, G.I.5
-
16
-
-
33747135785
-
C-reactive protein as a risk predictor: Do race/ethnicity and gender make a difference?
-
Albert MA, Ridker PM. C-reactive protein as a risk predictor: Do race/ethnicity and gender make a difference? Circulation 2006;114:e67-e74.
-
(2006)
Circulation
, vol.114
-
-
Albert, M.A.1
Ridker, P.M.2
-
17
-
-
0027459878
-
Adipose expression of tumor necrosis factor-alpha: Direct role in obesity-linked insulin resistance
-
Hotamisligil GS, Shargill NS, Spiegelman BM. Adipose expression of tumor necrosis factor-alpha: Direct role in obesity-linked insulin resistance. Science 1993;259:87-91.
-
(1993)
Science
, vol.259
, pp. 87-91
-
-
Hotamisligil, G.S.1
Shargill, N.S.2
Spiegelman, B.M.3
-
18
-
-
0029906375
-
Effects of an engineered human anti-TNF-alpha antibody (CDP571) on insulin sensitivity and glycemic control in patients with NIDDM
-
Ofei F, Hurel S, Newkirk J, Sopwith M, Taylor R. Effects of an engineered human anti-TNF-alpha antibody (CDP571) on insulin sensitivity and glycemic control in patients with NIDDM. Diabetes 1996;45:881-885.
-
(1996)
Diabetes
, vol.45
, pp. 881-885
-
-
Ofei, F.1
Hurel, S.2
Newkirk, J.3
Sopwith, M.4
Taylor, R.5
-
19
-
-
0035979775
-
Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of Ikkbeta
-
Yuan M, Konstantopoulos N, Lee J, et al. Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of Ikkbeta. Science 2001;293:1673-1677.
-
(2001)
Science
, vol.293
, pp. 1673-1677
-
-
Yuan, M.1
Konstantopoulos, N.2
Lee, J.3
-
20
-
-
38949119419
-
Salsalate improves glycemia and inflammatory parameters in obese young adults
-
Fleischman A, Shoelson SE, Bernier R, Goldfine AB. Salsalate improves glycemia and inflammatory parameters in obese young adults. Diabetes Care 2008;31:289-294.
-
(2008)
Diabetes Care
, vol.31
, pp. 289-294
-
-
Fleischman, A.1
Shoelson, S.E.2
Bernier, R.3
Goldfine, A.B.4
-
21
-
-
0036617308
-
Glycemic control of type 2 diabetes and severe periodontal disease in the US adult population
-
Tsai C, Hayes C, Taylor GW. Glycemic control of type 2 diabetes and severe periodontal disease in the US adult population. Community Dent Oral Epidemiol 2002;30:182-192.
-
(2002)
Community Dent Oral Epidemiol
, vol.30
, pp. 182-192
-
-
Tsai, C.1
Hayes, C.2
Taylor, G.W.3
-
22
-
-
14944340746
-
Oxidative stress and antioxidant treatment in diabetes
-
Scott JA, King GL. Oxidative stress and antioxidant treatment in diabetes. Ann N Y Acad Sci 2004;1031:204-213.
-
(2004)
Ann N Y Acad Sci
, vol.1031
, pp. 204-213
-
-
Scott, J.A.1
King, G.L.2
-
23
-
-
3042735579
-
Protein kinase C beta isoform inhibitors: A new treatment for diabetic cardiovascular diseases
-
He Z, King GL. Protein kinase C beta isoform inhibitors: A new treatment for diabetic cardiovascular diseases. Circulation 2004;110:7-9.
-
(2004)
Circulation
, vol.110
, pp. 7-9
-
-
He, Z.1
King, G.L.2
-
24
-
-
20844458389
-
Acute-phase markers of inflammation and glomerular structure in patients with type 2 diabetes
-
Dalla Vestra M, Mussap M, Gallina P, et al. Acute-phase markers of inflammation and glomerular structure in patients with type 2 diabetes. J Am Soc Nephrol 2005;16(Suppl. 1):S78-S82.
-
(2005)
J Am Soc Nephrol
, vol.16
, Issue.SUPPL. 1
-
-
Dalla Vestra, M.1
Mussap, M.2
Gallina, P.3
-
25
-
-
14644420204
-
Inflammatory markers and diabetic retinopathy in type 1 diabetes
-
Izuora KE, Chase HP, Jackson WE, et al. Inflammatory markers and diabetic retinopathy in type 1 diabetes. Diabetes Care 2005;28:714-715.
-
(2005)
Diabetes Care
, vol.28
, pp. 714-715
-
-
Izuora, K.E.1
Chase, H.P.2
Jackson, W.E.3
-
27
-
-
34250702110
-
The role of protein kinase C activation and the vascular complications of diabetes
-
Das Evcimen N, King GL. The role of protein kinase C activation and the vascular complications of diabetes. Pharmacol Res 2007;55:498-510.
-
(2007)
Pharmacol Res
, vol.55
, pp. 498-510
-
-
Das Evcimen, N.1
King, G.L.2
-
28
-
-
33644802450
-
Can protein kinase C beta-selective inhibitor, ruboxistaurin, stop vascular complications in diabetic patients?
-
He Z, King GL. Can protein kinase C beta-selective inhibitor, ruboxistaurin, stop vascular complications in diabetic patients? Diabetes Care 2005;28:2803-2805.
-
(2005)
Diabetes Care
, vol.28
, pp. 2803-2805
-
-
He, Z.1
King, G.L.2
-
29
-
-
33845522286
-
Reduction of diabetes-induced oxidative stress, fibrotic cytokine expression, and renal dysfunction in protein kinase C beta-null mice
-
Ohshiro Y, Ma RC, Yasuda Y, et al. Reduction of diabetes-induced oxidative stress, fibrotic cytokine expression, and renal dysfunction in protein kinase C beta-null mice. Diabetes 2006;55:3112-3120.
-
(2006)
Diabetes
, vol.55
, pp. 3112-3120
-
-
Ohshiro, Y.1
Ma, R.C.2
Yasuda, Y.3
-
30
-
-
0027942607
-
Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders
-
Aiello LP, Avery RL, Arrigg PG, et al. Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders. N Engl J Med 1994;331:1480-1487.
-
(1994)
N Engl J Med
, vol.331
, pp. 1480-1487
-
-
Aiello, L.P.1
Avery, R.L.2
Arrigg, P.G.3
-
31
-
-
8944246315
-
-
Jirousek MR, Gillig JR, Gonzalez CM, et al. (S)-13-[(dimethylamino) methyl]-10,11,14,15-tetrahydro-4, 9:16, 21-dimetheno-1H, 13H-dibenzo[e,k] pyrrolo[3, 4-h][1,4,13]oxadiazacyclohexadecene-1,3(2H)-d ione (LY333531) and related analogues: Isozyme selective inhibitors of protein kinase C beta. J Med Chem 1996;39:2664-2671.
-
Jirousek MR, Gillig JR, Gonzalez CM, et al. (S)-13-[(dimethylamino) methyl]-10,11,14,15-tetrahydro-4, 9:16, 21-dimetheno-1H, 13H-dibenzo[e,k] pyrrolo[3, 4-h][1,4,13]oxadiazacyclohexadecene-1,3(2H)-d ione (LY333531) and related analogues: Isozyme selective inhibitors of protein kinase C beta. J Med Chem 1996;39:2664-2671.
-
-
-
-
32
-
-
2642709170
-
Characterization of vascular endothelial growth factor's effect on the activation of protein kinase C, its isoforms, and endothelial cell growth
-
Xia P, Aiello LP, Ishii H, et al. Characterization of vascular endothelial growth factor's effect on the activation of protein kinase C, its isoforms, and endothelial cell growth. J Clin Invest 1996;98:2018-2026.
-
(1996)
J Clin Invest
, vol.98
, pp. 2018-2026
-
-
Xia, P.1
Aiello, L.P.2
Ishii, H.3
-
33
-
-
0034053336
-
Amelioration of accelerated diabetic mesangial expansion by treatment with a PKC beta inhibitor in diabetic db/db mice, a rodent model for type 2 diabetes
-
Koya D, Haneda M, Nakagawa H, et al. Amelioration of accelerated diabetic mesangial expansion by treatment with a PKC beta inhibitor in diabetic db/db mice, a rodent model for type 2 diabetes. FASEB J 2000;14:439-447.
-
(2000)
FASEB J
, vol.14
, pp. 439-447
-
-
Koya, D.1
Haneda, M.2
Nakagawa, H.3
-
34
-
-
28644442122
-
The effect of ruboxistaurin on nephropathy in type 2 diabetes
-
Tuttle KR, Bakris GL, Toto RD, McGill JB, Hu K, Anderson PW. The effect of ruboxistaurin on nephropathy in type 2 diabetes. Diabetes Care 2005;28:2686-2690.
-
(2005)
Diabetes Care
, vol.28
, pp. 2686-2690
-
-
Tuttle, K.R.1
Bakris, G.L.2
Toto, R.D.3
McGill, J.B.4
Hu, K.5
Anderson, P.W.6
-
35
-
-
33751520614
-
Effect of ruboxistaurin on visual loss in patients with diabetic retinopathy
-
Aiello LP, Davis MD, Girach A, et al. Effect of ruboxistaurin on visual loss in patients with diabetic retinopathy. Ophthalmology 2006;113:2221-2230.
-
(2006)
Ophthalmology
, vol.113
, pp. 2221-2230
-
-
Aiello, L.P.1
Davis, M.D.2
Girach, A.3
-
36
-
-
33947236725
-
Effect of ruboxistaurin in patients with diabetic macular edema: Thirty-month results of the randomized PKC-DMES clinical trial
-
PKC-DMES Study Group
-
PKC-DMES Study Group. Effect of ruboxistaurin in patients with diabetic macular edema: Thirty-month results of the randomized PKC-DMES clinical trial. Arch Ophthalmol 2007;125:318-324.
-
(2007)
Arch Ophthalmol
, vol.125
, pp. 318-324
-
-
-
37
-
-
0038176445
-
Obesity and periodontal disease in young, middle-aged, and older adults
-
Al-Zahrani MS, Bissada NF, Borawski EA. Obesity and periodontal disease in young, middle-aged, and older adults. Journal of Periodontology 2003;74:610-615.
-
(2003)
Journal of Periodontology
, vol.74
, pp. 610-615
-
-
Al-Zahrani, M.S.1
Bissada, N.F.2
Borawski, E.A.3
-
38
-
-
28644450804
-
A proposed model linking inflammation to obesity, diabetes, and periodontal infections
-
Genco R, Grossi S, Ho A, Nishimura F, Murayama Y. A proposed model linking inflammation to obesity, diabetes, and periodontal infections. Journal of Periodontology 2005;76:2075-2084.
-
(2005)
Journal of Periodontology
, vol.76
, pp. 2075-2084
-
-
Genco, R.1
Grossi, S.2
Ho, A.3
Nishimura, F.4
Murayama, Y.5
-
39
-
-
34247582450
-
Obesity and periodontal disease
-
Ritchie C. Obesity and periodontal disease. Periodontology 2000 2007;44:154-163.
-
(2007)
Periodontology 2000
, vol.44
, pp. 154-163
-
-
Ritchie, C.1
|