메뉴 건너뛰기




Volumn 79, Issue 8 SUPPL., 2008, Pages 1527-1534

The role of inflammatory cytokines in diabetes and its complications

Author keywords

Complications; Diabetes; Hyperglycemia; Inflammation; Insulin resistance; Periodontal disease

Indexed keywords

AUTACOID; CYTOKINE;

EID: 49449117005     PISSN: 00223492     EISSN: None     Source Type: Journal    
DOI: 10.1902/jop.2008.080246     Document Type: Conference Paper
Times cited : (538)

References (39)
  • 1
    • 49449088451 scopus 로고
    • Diabetes data & trends
    • CDC Center for Disease Control and Prevention, United States, Available at:, Accessed February 9, 2008
    • (CDC) Center for Disease Control and Prevention. Diabetes data & trends. Number (in millions) of persons with diagnosed diabetes, United States, 1980-2005. Available at: http://www.cdc.gov/diabetes/statistics/prev/national/ figpersons.htm. Accessed February 9, 2008.
    • (1980) Number (in millions) of persons with diagnosed diabetes
  • 2
    • 49449087876 scopus 로고    scopus 로고
    • CDC Center for Disease Control and Prevention, Available at:, Accessed February 9, 2008
    • (CDC) Center for Disease Control and Prevention. Diabetes data & trends. Overweight and obesity. U.S. Obesity Trends 1985-2006. Available at: http://www.cdc.gov/nccdphp/dnpa/obesity/trend/maps/. Accessed February 9, 2008.
    • Diabetes data & trends. Overweight and obesity. U.S. Obesity Trends 1985-2006
  • 3
    • 2342466734 scopus 로고    scopus 로고
    • Global prevalence of diabetes: Estimates for the year 2000 and projections for 2030
    • Wild S, Roglic G, Green A, Sicree R, King H. Global prevalence of diabetes: Estimates for the year 2000 and projections for 2030. Diabetes Care 2004;27:1047-1053.
    • (2004) Diabetes Care , vol.27 , pp. 1047-1053
    • Wild, S.1    Roglic, G.2    Green, A.3    Sicree, R.4    King, H.5
  • 4
    • 0035753516 scopus 로고    scopus 로고
    • The relationship between periodontal diseases and diabetes: An overview
    • Soskolne WA, Klinger A. The relationship between periodontal diseases and diabetes: An overview. Ann Periodontol 2001;6:91-98.
    • (2001) Ann Periodontol , vol.6 , pp. 91-98
    • Soskolne, W.A.1    Klinger, A.2
  • 5
    • 49449083437 scopus 로고    scopus 로고
    • CDC Center for Disease Control and Prevention, United States, General information. Available at:, Accessed February 9, 2008
    • (CDC) Center for Disease Control and Prevention. National diabetes fact sheet. United States, 2005 General information. Available at: http://apps.nccd.cdc.gov/DDTSTRS/template/ndfs_2005.pdf. Accessed February 9, 2008.
    • (2005)
  • 6
    • 6444241336 scopus 로고    scopus 로고
    • Epidemiology of childhood type 2 diabetes in the developing world
    • Singh R, Shaw J, Zimmet P. Epidemiology of childhood type 2 diabetes in the developing world. Pediatr Diabetes 2004;5:154-168.
    • (2004) Pediatr Diabetes , vol.5 , pp. 154-168
    • Singh, R.1    Shaw, J.2    Zimmet, P.3
  • 7
    • 7444228518 scopus 로고    scopus 로고
    • Elevated C-reactive protein levels do not correspond to autoimmunity in type 1 diabetes
    • Treszl A, Szereday L, Doria A, King GL, Orban T. Elevated C-reactive protein levels do not correspond to autoimmunity in type 1 diabetes. Diabetes Care 2004;27:2769-2770.
    • (2004) Diabetes Care , vol.27 , pp. 2769-2770
    • Treszl, A.1    Szereday, L.2    Doria, A.3    King, G.L.4    Orban, T.5
  • 8
    • 35748942911 scopus 로고    scopus 로고
    • Evidence of increased inflammation and microcirculatory abnormalities in patients with type 1 diabetes and their role in microvascular complications
    • Devaraj S, Cheung AT, Jialal I, et al. Evidence of increased inflammation and microcirculatory abnormalities in patients with type 1 diabetes and their role in microvascular complications. Diabetes 2007;56:2790-2796.
    • (2007) Diabetes , vol.56 , pp. 2790-2796
    • Devaraj, S.1    Cheung, A.T.2    Jialal, I.3
  • 9
    • 0036066485 scopus 로고    scopus 로고
    • High white blood cell count is associated with a worsening of insulin sensitivity and predicts the development of type 2 diabetes
    • Vozarova B, Weyer C, Lindsay RS, Pratley RE, Bogardus C, Tataranni PA. High white blood cell count is associated with a worsening of insulin sensitivity and predicts the development of type 2 diabetes. Diabetes 2002;51:455-461.
    • (2002) Diabetes , vol.51 , pp. 455-461
    • Vozarova, B.1    Weyer, C.2    Lindsay, R.S.3    Pratley, R.E.4    Bogardus, C.5    Tataranni, P.A.6
  • 10
    • 0035908632 scopus 로고    scopus 로고
    • C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus
    • Pradhan AD, Manson JE, Rifai N, Buring JE, Ridker PM. C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus. JAMA 2001;286:327-334.
    • (2001) JAMA , vol.286 , pp. 327-334
    • Pradhan, A.D.1    Manson, J.E.2    Rifai, N.3    Buring, J.E.4    Ridker, P.M.5
  • 11
    • 0037434058 scopus 로고    scopus 로고
    • C-reactive protein as a predictor for incident diabetes mellitus among middle-aged men: Results from the MONICA Augsburg cohort study, 1984-1998
    • Thorand B, Löwel H, Schneider A, et al. C-reactive protein as a predictor for incident diabetes mellitus among middle-aged men: Results from the MONICA Augsburg cohort study, 1984-1998. Arch Intern Med 2003;163:93-99.
    • (2003) Arch Intern Med , vol.163 , pp. 93-99
    • Thorand, B.1    Löwel, H.2    Schneider, A.3
  • 12
    • 0035381046 scopus 로고    scopus 로고
    • Obesity: A rational target for managing diabetes mellitus
    • Mooradian AD. Obesity: A rational target for managing diabetes mellitus. Growth Horm IGF Res 2001;11(Suppl. A):S79-S83.
    • (2001) Growth Horm IGF Res , vol.11 , Issue.SUPPL. A
    • Mooradian, A.D.1
  • 14
    • 33845866857 scopus 로고    scopus 로고
    • Inflammation and metabolic disorders
    • Hotamisligil GS. Inflammation and metabolic disorders. Nature 2006;444:860-867.
    • (2006) Nature , vol.444 , pp. 860-867
    • Hotamisligil, G.S.1
  • 15
    • 1642377274 scopus 로고    scopus 로고
    • Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes
    • Petersen KF, Dufour S, Befroy D, Garcia R, Shulman GI. Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes. N Engl J Med 2004;350:664-671.
    • (2004) N Engl J Med , vol.350 , pp. 664-671
    • Petersen, K.F.1    Dufour, S.2    Befroy, D.3    Garcia, R.4    Shulman, G.I.5
  • 16
    • 33747135785 scopus 로고    scopus 로고
    • C-reactive protein as a risk predictor: Do race/ethnicity and gender make a difference?
    • Albert MA, Ridker PM. C-reactive protein as a risk predictor: Do race/ethnicity and gender make a difference? Circulation 2006;114:e67-e74.
    • (2006) Circulation , vol.114
    • Albert, M.A.1    Ridker, P.M.2
  • 17
    • 0027459878 scopus 로고
    • Adipose expression of tumor necrosis factor-alpha: Direct role in obesity-linked insulin resistance
    • Hotamisligil GS, Shargill NS, Spiegelman BM. Adipose expression of tumor necrosis factor-alpha: Direct role in obesity-linked insulin resistance. Science 1993;259:87-91.
    • (1993) Science , vol.259 , pp. 87-91
    • Hotamisligil, G.S.1    Shargill, N.S.2    Spiegelman, B.M.3
  • 18
    • 0029906375 scopus 로고    scopus 로고
    • Effects of an engineered human anti-TNF-alpha antibody (CDP571) on insulin sensitivity and glycemic control in patients with NIDDM
    • Ofei F, Hurel S, Newkirk J, Sopwith M, Taylor R. Effects of an engineered human anti-TNF-alpha antibody (CDP571) on insulin sensitivity and glycemic control in patients with NIDDM. Diabetes 1996;45:881-885.
    • (1996) Diabetes , vol.45 , pp. 881-885
    • Ofei, F.1    Hurel, S.2    Newkirk, J.3    Sopwith, M.4    Taylor, R.5
  • 19
    • 0035979775 scopus 로고    scopus 로고
    • Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of Ikkbeta
    • Yuan M, Konstantopoulos N, Lee J, et al. Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of Ikkbeta. Science 2001;293:1673-1677.
    • (2001) Science , vol.293 , pp. 1673-1677
    • Yuan, M.1    Konstantopoulos, N.2    Lee, J.3
  • 20
    • 38949119419 scopus 로고    scopus 로고
    • Salsalate improves glycemia and inflammatory parameters in obese young adults
    • Fleischman A, Shoelson SE, Bernier R, Goldfine AB. Salsalate improves glycemia and inflammatory parameters in obese young adults. Diabetes Care 2008;31:289-294.
    • (2008) Diabetes Care , vol.31 , pp. 289-294
    • Fleischman, A.1    Shoelson, S.E.2    Bernier, R.3    Goldfine, A.B.4
  • 21
    • 0036617308 scopus 로고    scopus 로고
    • Glycemic control of type 2 diabetes and severe periodontal disease in the US adult population
    • Tsai C, Hayes C, Taylor GW. Glycemic control of type 2 diabetes and severe periodontal disease in the US adult population. Community Dent Oral Epidemiol 2002;30:182-192.
    • (2002) Community Dent Oral Epidemiol , vol.30 , pp. 182-192
    • Tsai, C.1    Hayes, C.2    Taylor, G.W.3
  • 22
    • 14944340746 scopus 로고    scopus 로고
    • Oxidative stress and antioxidant treatment in diabetes
    • Scott JA, King GL. Oxidative stress and antioxidant treatment in diabetes. Ann N Y Acad Sci 2004;1031:204-213.
    • (2004) Ann N Y Acad Sci , vol.1031 , pp. 204-213
    • Scott, J.A.1    King, G.L.2
  • 23
    • 3042735579 scopus 로고    scopus 로고
    • Protein kinase C beta isoform inhibitors: A new treatment for diabetic cardiovascular diseases
    • He Z, King GL. Protein kinase C beta isoform inhibitors: A new treatment for diabetic cardiovascular diseases. Circulation 2004;110:7-9.
    • (2004) Circulation , vol.110 , pp. 7-9
    • He, Z.1    King, G.L.2
  • 24
    • 20844458389 scopus 로고    scopus 로고
    • Acute-phase markers of inflammation and glomerular structure in patients with type 2 diabetes
    • Dalla Vestra M, Mussap M, Gallina P, et al. Acute-phase markers of inflammation and glomerular structure in patients with type 2 diabetes. J Am Soc Nephrol 2005;16(Suppl. 1):S78-S82.
    • (2005) J Am Soc Nephrol , vol.16 , Issue.SUPPL. 1
    • Dalla Vestra, M.1    Mussap, M.2    Gallina, P.3
  • 25
    • 14644420204 scopus 로고    scopus 로고
    • Inflammatory markers and diabetic retinopathy in type 1 diabetes
    • Izuora KE, Chase HP, Jackson WE, et al. Inflammatory markers and diabetic retinopathy in type 1 diabetes. Diabetes Care 2005;28:714-715.
    • (2005) Diabetes Care , vol.28 , pp. 714-715
    • Izuora, K.E.1    Chase, H.P.2    Jackson, W.E.3
  • 26
    • 33644693852 scopus 로고    scopus 로고
    • Serum inflammatory markers in diabetic retinopathy
    • Meleth AD, Agron E, Chan CC, et al. Serum inflammatory markers in diabetic retinopathy. Invest Ophthalmol Vis Sci 2005;46:4295-4301.
    • (2005) Invest Ophthalmol Vis Sci , vol.46 , pp. 4295-4301
    • Meleth, A.D.1    Agron, E.2    Chan, C.C.3
  • 27
    • 34250702110 scopus 로고    scopus 로고
    • The role of protein kinase C activation and the vascular complications of diabetes
    • Das Evcimen N, King GL. The role of protein kinase C activation and the vascular complications of diabetes. Pharmacol Res 2007;55:498-510.
    • (2007) Pharmacol Res , vol.55 , pp. 498-510
    • Das Evcimen, N.1    King, G.L.2
  • 28
    • 33644802450 scopus 로고    scopus 로고
    • Can protein kinase C beta-selective inhibitor, ruboxistaurin, stop vascular complications in diabetic patients?
    • He Z, King GL. Can protein kinase C beta-selective inhibitor, ruboxistaurin, stop vascular complications in diabetic patients? Diabetes Care 2005;28:2803-2805.
    • (2005) Diabetes Care , vol.28 , pp. 2803-2805
    • He, Z.1    King, G.L.2
  • 29
    • 33845522286 scopus 로고    scopus 로고
    • Reduction of diabetes-induced oxidative stress, fibrotic cytokine expression, and renal dysfunction in protein kinase C beta-null mice
    • Ohshiro Y, Ma RC, Yasuda Y, et al. Reduction of diabetes-induced oxidative stress, fibrotic cytokine expression, and renal dysfunction in protein kinase C beta-null mice. Diabetes 2006;55:3112-3120.
    • (2006) Diabetes , vol.55 , pp. 3112-3120
    • Ohshiro, Y.1    Ma, R.C.2    Yasuda, Y.3
  • 30
    • 0027942607 scopus 로고
    • Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders
    • Aiello LP, Avery RL, Arrigg PG, et al. Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders. N Engl J Med 1994;331:1480-1487.
    • (1994) N Engl J Med , vol.331 , pp. 1480-1487
    • Aiello, L.P.1    Avery, R.L.2    Arrigg, P.G.3
  • 31
    • 8944246315 scopus 로고    scopus 로고
    • Jirousek MR, Gillig JR, Gonzalez CM, et al. (S)-13-[(dimethylamino) methyl]-10,11,14,15-tetrahydro-4, 9:16, 21-dimetheno-1H, 13H-dibenzo[e,k] pyrrolo[3, 4-h][1,4,13]oxadiazacyclohexadecene-1,3(2H)-d ione (LY333531) and related analogues: Isozyme selective inhibitors of protein kinase C beta. J Med Chem 1996;39:2664-2671.
    • Jirousek MR, Gillig JR, Gonzalez CM, et al. (S)-13-[(dimethylamino) methyl]-10,11,14,15-tetrahydro-4, 9:16, 21-dimetheno-1H, 13H-dibenzo[e,k] pyrrolo[3, 4-h][1,4,13]oxadiazacyclohexadecene-1,3(2H)-d ione (LY333531) and related analogues: Isozyme selective inhibitors of protein kinase C beta. J Med Chem 1996;39:2664-2671.
  • 32
    • 2642709170 scopus 로고    scopus 로고
    • Characterization of vascular endothelial growth factor's effect on the activation of protein kinase C, its isoforms, and endothelial cell growth
    • Xia P, Aiello LP, Ishii H, et al. Characterization of vascular endothelial growth factor's effect on the activation of protein kinase C, its isoforms, and endothelial cell growth. J Clin Invest 1996;98:2018-2026.
    • (1996) J Clin Invest , vol.98 , pp. 2018-2026
    • Xia, P.1    Aiello, L.P.2    Ishii, H.3
  • 33
    • 0034053336 scopus 로고    scopus 로고
    • Amelioration of accelerated diabetic mesangial expansion by treatment with a PKC beta inhibitor in diabetic db/db mice, a rodent model for type 2 diabetes
    • Koya D, Haneda M, Nakagawa H, et al. Amelioration of accelerated diabetic mesangial expansion by treatment with a PKC beta inhibitor in diabetic db/db mice, a rodent model for type 2 diabetes. FASEB J 2000;14:439-447.
    • (2000) FASEB J , vol.14 , pp. 439-447
    • Koya, D.1    Haneda, M.2    Nakagawa, H.3
  • 35
    • 33751520614 scopus 로고    scopus 로고
    • Effect of ruboxistaurin on visual loss in patients with diabetic retinopathy
    • Aiello LP, Davis MD, Girach A, et al. Effect of ruboxistaurin on visual loss in patients with diabetic retinopathy. Ophthalmology 2006;113:2221-2230.
    • (2006) Ophthalmology , vol.113 , pp. 2221-2230
    • Aiello, L.P.1    Davis, M.D.2    Girach, A.3
  • 36
    • 33947236725 scopus 로고    scopus 로고
    • Effect of ruboxistaurin in patients with diabetic macular edema: Thirty-month results of the randomized PKC-DMES clinical trial
    • PKC-DMES Study Group
    • PKC-DMES Study Group. Effect of ruboxistaurin in patients with diabetic macular edema: Thirty-month results of the randomized PKC-DMES clinical trial. Arch Ophthalmol 2007;125:318-324.
    • (2007) Arch Ophthalmol , vol.125 , pp. 318-324
  • 38
    • 28644450804 scopus 로고    scopus 로고
    • A proposed model linking inflammation to obesity, diabetes, and periodontal infections
    • Genco R, Grossi S, Ho A, Nishimura F, Murayama Y. A proposed model linking inflammation to obesity, diabetes, and periodontal infections. Journal of Periodontology 2005;76:2075-2084.
    • (2005) Journal of Periodontology , vol.76 , pp. 2075-2084
    • Genco, R.1    Grossi, S.2    Ho, A.3    Nishimura, F.4    Murayama, Y.5
  • 39
    • 34247582450 scopus 로고    scopus 로고
    • Obesity and periodontal disease
    • Ritchie C. Obesity and periodontal disease. Periodontology 2000 2007;44:154-163.
    • (2007) Periodontology 2000 , vol.44 , pp. 154-163
    • Ritchie, C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.