Plasma and mucosal fluid from hiv type 1-infected patients but not from HIV type 1-exposed uninfected subjects prevent HIV type 1-exposed DC from infecting other target cells

AIDS Research and Human Retroviruses

Volumn 23, Issue 1, 2007, Pages 101-106

  Söderlund, Johan ^a   Hirbod, Taha ^a   Smed Sörensen, Anna ^a   Johansson, Ulrika ^a   Kimani, Joshua ^b   Plummer, Francis ^c   Spetz, Anna Lena ^a   Andersson, Jan ^a   Kaul, Rupert ^b   Broliden, Kristina ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b UNIVERSITY OF NAIROBI   (Kenya)

^c UNIVERSITY OF MANITOBA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CD209 ANTIGEN; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MONOCYTE CHEMOTACTIC PROTEIN; RANTES;

ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; DENDRITIC CELL; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMORAL IMMUNITY; IN VITRO STUDY; KENYA; PRIORITY JOURNAL; SERODIAGNOSIS; TARGET CELL; VIRUS INFECTION; VIRUS NEUTRALIZATION;

CELLS, CULTURED; CERVIX UTERI; COCULTURE TECHNIQUES; COHORT STUDIES; DENDRITIC CELLS; DNA, VIRAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HIV INFECTIONS; HIV SERONEGATIVITY; HIV-1; HUMANS; IMMUNITY, MUCOSAL; LEUKOCYTES, MONONUCLEAR; NEUTRALIZATION TESTS; PROSTITUTION; VAGINA;

EID: 33846818809     PISSN: 08892229     EISSN: None     Source Type: Journal    
DOI: 10.1089/aid.2005.0104     Document Type: Article

References (21)

1. Devito C, Hinkula J, Kaul R, et al.: Mucosal and plasma IgA from HIV-exposed seronegative individuals neutralize a primary HIV-1 isolate. AIDS 2000;14:1917-1920.
2. + lymphocyte responses in the cervix of HIV-1-resistant prostitutes in Nairobi. J Immunol 2000;164:1602-1611.
3. Pope M and Haase AT: Transmission, acute HIV-1 infection and the quest for strategies to prevent infection. Nat Med 2003;9:847-852.
4. Ayehunie S, Garcia-Zepeda EA, Hoxie JA, et al.: Human immunodeficiency virus-1 entry into purified blood dendritic cells through CC and CXC chemokine coreceptors. Blood 1997;90:1379-1386.
5. Geijtenbeek TB, Kwon DS, Torensma R, et al.: DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells. Cell 2000;100:587-597.
6. Turville SG, Cameron PU, Handley A, et al.: Diversity of receptors binding HIV on DC subsets. Nat Immunol 2002;3:975-983.
7. Frank I, Kacani L, Stoiber H, et al.: Human immunodeficiency virus type 1 derived from cocultures of immature dendritic cells with autologous T cells carries T-cell-specific molecules on its surface and is highly infectious. J Virol 1999;73:3449-3454.
8. Veazey RS and Lackner AA: HIV swiftly guts the immune system. Nat Med 2005;11:469-470.
9. + T cells. Nature 2005;434:1148-1151.
10. Shi Y, Albert J, Francis G, Holmes H, and Fenyo EM: A new cell line-based neutralization assay for primary HIV type 1 isolates. AIDS Res Hum Retroviruses 2002;18(13):957-967.
11. Moore JP, Cao Y, Qing L, et al.: Primary isolates of human immunodeficiency virus type 1 are relatively resistant to neutralization by monoclonal antibodies to gp120, and their neutralization is not predicted by studies with monomeric gp120. J Virol 1995;69:101-109.
12. Romani N, Reider D, and Heuer M: Generation of mature dendritic cells from human blood. An improved method with special regard to clinical applicability. J Immunol Methods 1996;196(2):137-151.
13. Lore K, Sonnerborg A, Spetz AL, Andersson U, and Andersson J: Immunocytochemical detection of cytokines and chemokines in Langerhans cells and in vitro derived dendritic cells. J Immunol Methods 1998;214(1-2):97- 111.
14. Hu Q, Frank I, Williams V, et al.: Blockade of attachment and fusion receptors inhibits HIV-1 infection of human cervical tissue. J Exp Med 2004;199:1065-1075.
15. Frankel SS, Steinman RM, Michael NL, et al.: Neutralizing monoclonal antibodies block human immunodeficiency virus type 1 infection of dendritic cells and transmission to T cells. J Virol 1998;72:9788-9794.
16. Kutteh WH, Prince SJ, Hammond KR, Kutteh CC, and Mestecky J: Variations in immunoglobulins and IgA subclasses of human uterine cervical secretions around the time of ovulation. Clin Exp Immunol 1996;104:538-542.
17. Lopalco L, Barassi C, Pastori C, et al.: CCR5-reactive antibodies in seronegative partners of HIV-seropositive individuals downmodulate surface CCR5 in vivo and neutralize the infectivity of R5 strains of HIV-I in vitro. J Immunol 2000;164:3426-3433.
18. Trabattoni D, Caputo SL, Maffeis G, et al.: Human alpha defensin in HIV-exposed but uninfected individuals. J Acquir Immune Defic Syndr 2004;35:455-463.
19. Iqbal SM, Ball TB, Kimani J, et al.: Elevated T cell counts and RANTES expression in the genital mucosa of HIV-1-resistant Kenyan commercial sex workers. J Infect Dis 2005;192:728-738.
20. Holl V, Peressin M, Schmidt S, et al.: Efficient inhibition of HIV-1 replication in human immature monocyte-derived dendritic cells by purified anti-HIV-1 IgG without induction of maturation. Blood 2006;107:4466-4474.
21. Brandtzaeg P, Baekkevold ES, Farstad IN, et al.: Regional specialization in the mucosal immune system: What happens in the microcompartments? Immunol Today 1999;20:141-150.