Characterization of HIV-1-specific cytotoxic T lymphocytes expressing the mucosal lymphocyte integrin CD103 in rectal and duodenal lymphoid tissue of HIV-1-infected subjects

Virology

Volumn 270, Issue 2, 2000, Pages 317-327

  Shacklett, Barbara L ^a   Beadle, Thomas J ^a   Pacheco, Paulo A ^b   Grendell, James H ^b   Haslett, Patrick A J ^a   King, Abigail S ^c   Ogg, Graham S ^c   Basuk, Paul M ^b   Nixon, Douglas F ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

^b Department of Obstetrics Gynecology   (United States)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CD103 ANTIGEN; INTEGRIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; UNCLASSIFIED DRUG;

ANTIGEN EXPRESSION; ANTIGEN SPECIFICITY; ARTICLE; CELL SPECIFICITY; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INTESTINE LYMPHATIC TISSUE; LYMPHOCYTE PROLIFERATION; MAJOR HISTOCOMPATIBILITY COMPLEX RESTRICTION; MUCOSAL IMMUNITY; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL; TISSUE DISTRIBUTION;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; RNA VIRUSES;

EID: 0034630946     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.2000.0299     Document Type: Article

References (53)

1. Amerongen H. M., Weltzin R., Farnet C. M., Michetti P., Haseltine W. A., Neutra M. R. Transepithelial transport of HIV-1 by intestinal M cells: A mechanism for transmission of AIDS. J. Acquired Immune Defic. Syndr. 4:1991;760-765.
2. Belyakov I. M., Derby M. A., Ahlers J. D., Kelsall B. L., Earl P., Moss B., Strober W., Berzofsky J. A. Mucosal immunization with HIV-1 peptide vaccine induces mucosal and systemic cytotoxic T lymphocytes and protective immunity in mice against intrarectal recombinant HIV-vaccinia challenge. Proc. Natl. Acad. Sci. USA. 95:1998;1709-1714.
3. Bennett S. R., Carbone F. R., Karamalis F., Flavell R. A., Miller J. F., Heath W. R. Help for cytotoxic-T-cell responses is mediated by CD40 signalling. Nature. 393:1998;478-480.
4. Bomsel M. Transcytosis of infectious human immunodeficiency virus across a tight human epithelial cell line barrier. Nat. Med. 3:1997;42-47.
5. Brandtzaeg P., Farstad I. N., Haraldsen G. Regional specialization in the mucosal immune system: Primed cells do not always home along the same track. Immunol. Today. 20:1999;267-277.
6. Cepek K. L., Shaw S. K., Parker C. M., Russell G. J., Morrow J. S., Rimm D. L., Brenner M. B. Adhesion between epithelial cells and T lymphocytes mediated by E-cadherin and the alpha E beta 7 integrin. Nature. 372:1994;190-193.
7. Chui D. W., Owen R. L. AIDS and the gut. J. Gastroenterol. Hepatol. 9:1994;291-303.
8. Coligan J., Kruisbeek A., Margulies D., Shevach E., Strober W. Current Protocols in Immunology. 1999;Wiley Interscience, New York.
9. Couedel-Courteille A., Le Grand R., Tulliez M., Guillet J., Venet A. Direct ex vivo simian immunodeficiency virus (SIV)-specific cytotoxic activity detected from small intestine intraepithelial lymphocytes of SIV-infected macaques at an advanced stage of infection. J. Virol. 71:1997;1052-1057.
10. Doherty P. C., Topham D. J., Tripp R. A., Cardin R. D., Brooks J. W., Stevenson P. G. Effector CD4+ and CD8+ T-cell mechanisms in the control of respiratory virus infections. Immunol. Rev. 159:1997;105-117.
11. Fackler O. T., Schafer M., Schmidt W., Zippel T., Heise W., Schneider T., Zeitz M., Riecken E. O., Mueller-Lantzsch N., Ullrich R. HIV-1 p24 but not proviral load is increased in the intestinal mucosa compared with the peripheral blood in HIV-infected patients. AIDS. 12:1998;139-146.
12. Fantini J., Yahi N., Chermann J. C. Human immunodeficiency virus can infect the apical and basolateral surfaces of human colonic epithelial cells. Proc. Natl. Acad. Sci. USA. 88:1991;9297-9301.
13. Frankel S. S., Wenig B. M., Burke A. P., Mannan P., Thompson L. D., Abbondanzo S. L., Nelson A. M., Pope M., Steinman R. M. Replication of HIV-1 in dendritic cell-derived syncytia at the mucosal surface of the adenoid. Science. 272:1996;115-117.
14. Heise C., Miller C. J., Lackner A., Dandekar S. Primary acute simian immunodeficiency virus infection of intestinal lymphoid tissue is associated with gastrointestinal dysfunction. J. Infect. Dis. 169:1994;1116-1120.
15. Howie D., Spencer J., DeLord D., Pitzalis C., Wathen N. C., Dogan A., Akbar A., MacDonald T. T. Extrathymic T cell differentiation in the human intestine early in life. J. Immunol. 161:1998;5862-5872.
16. Hu P. F., Hultin L. E., Hultin P., Hausner M. A., Hirji K., Jewett A., Bonavida B., Detels R., Giorgi J. V. Natural killer cell immunodeficiency in HIV disease is manifest by profoundly decreased numbers of CD16+CD56+ cells and expansion of a population of CD16dimCD56- cells with low lytic activity. J. Acquired Immune Defic. Syndr. Hum. Retrovirol. 10:1995;331-340.
17. Hussain L. A., Kelly C. G., Hecht E. M., Fellowes R., Jourdan M., Lehner T. The expression of Fc receptors for immunoglobulin G in human rectal epithelium. AIDS. 5:1991;1089-1094.
18. Jarry A., Cortez A., Rene E., Muzeau F., Brousse N. Infected cells and immune cells in the gastrointestinal tract of AIDS patients. An immunohistochemical study of 127 cases. Histopathology. 16:1990;133-140.
19. Kalams S. A., Walker B. D. The critical need for CD4 help in maintaining effective cytotoxic T lymphocyte responses. J. Exp. Med. 188:1998;2199-2204.
20. Klavinskis L. S., Bergmeier L. A., Gao L., Mitchell E., Ward R. G., Layton G., Brookes R., Meyers N. J., Lehner T. Mucosal or targeted lymph node immunization of macaques with a particulate SIVp27 protein elicits virus-specific CTL in the genito-rectal mucosa and draining lymph nodes. J. Immunol. 157:1996;2521-2527.
21. Kotler D. P., Reka S., Borcich A., Cronin W. J. Detection, localization, and quantitation of HIV-associated antigens in intestinal biopsies from patients with HIV. Am. J. Pathol. 139:1991;823-830.
22. Lapenta C., Boirivant M., Marini M., Santini S. M., Logozzi M., Viora M., Belardelli F., Fais S. Human intestinal lamina propria lymphocytes are naturally permissive to HIV-1 infection. Eur. J. Immunol. 29:1999;1202-1208.
23. Larsson M., Jin X., Ramratnam B., Ogg G. S., Engelmayer J., Demoitie M. A., McMichael A. J., Cox W. I., Steinman R. M., Nixon D., Bhardwaj N. A recombinant vaccinia virus based ELISPOT assay detects high frequencies of Pol-specific CD8 T cells in HIV-1-positive individuals. AIDS. 13:1999;767-777.
24. Lefrancois L. Extrathymic differentiation of intraepithelial lymphocytes: Generation of a separate and unequal T-cell repertoire? Immunol. Today. 12:1991;436-438.
25. Lefrancois L., Parker C. M., Olson S., Muller W., Wagner N., Puddington L. The role of beta7 integrins in CD8 T cell trafficking during an antiviral immune response. J. Exp. Med. 189:1999;1631-1638.
26. Lewis D. E., Puck J. M., Babcock G. F., Rich R. R. Disproportionate expansion of a minor T cell subset in patients with lymphadenopathy syndrome and acquired immunodeficiency syndrome. J. Infect. Dis. 151:1985;555-559.
27. London S. D., Cebra-Thomas J. A., Rubin D. H., Cebra J. J. CD8 lymphocyte subpopulations in Peyer's patches induced by reovirus serotype 1 infection. J. Immunol. 144:1990;3187-3194.
28. Lundqvist C., Baranov V., Hammarstrom S., Athlin L., Hammarstrom M. Intra-epithelial lymphocytes. Evidence for regional specialization and extrathymic T cell maturation in the human gut epithelium. Int. Immunol. 7:1995;1473-1487.
29. Lynch S., Kelleher D., McManus R., O'Farrelly C. RAG1 and RAG2 expression in human intestinal epithelium: Evidence of extrathymic T cell differentiation. Eur. J. Immunol. 25:1995;1143-1147.
30. Margolick J. B., Scott E. R., Odaka N., Saah A. J. Flow cytometric analysis of gamma delta T cells and natural killer cells in HIV-1 infection. Clin. Immunol. Immunopathol. 58:1991;126-138.
31. Markowitz M., Vesanen M., Tenner-Racz K., Cao Y., Binley J. M., Talal A., Hurley A., Jin X., Chaudhry M. R., Yaman M., Frankel S., Heath-Chiozzi M., Leonard J. M., Moore J. P., Racz P., Nixon D. F., Ho D. D. The effect of commencing combination antiretroviral therapy soon after human immunodeficiency virus type 1 infection on viral replication and antiviral immune responses. J. Infect. Dis. 179:1999;527-537.
32. Matloubian M., Concepcion R. J., Ahmed R. CD4+ T cells are required to sustain CD8+ cytotoxic T-cell responses during chronic viral infection. J. Virol. 68:1994;8056-8063.
33. Mattapallil J. J., Smit-McBride Z., McChesney M., Dandekar S. Intestinal intraepithelial lymphocytes are primed for gamma interferon and MIP-1beta expression and display antiviral cytotoxic activity despite severe CD4(+) T-cell depletion in primary simian immunodeficiency virus infection. J. Virol. 72:1998;6421-6429.
34. Mowat A., Viney J. The anatomical basis of intestinal immunity. Immunol. Rev. 156:1997;145-166.
35. Mulder J., McKinney N., Christopherson C., Sninsky J., Greenfield L., Kwok S. Rapid and simple PCR assay for quantitation of human immunodeficiency virus type 1 RNA in plasma: Application to acute retroviral infection. J. Clin. Microbiol. 32:1994;292-300.
36. Murphey-Corb M., Wilson L. A., Trichel A. M., Roberts D. E., Xu K., Ohkawa S., Woodson B., Bohm R., Blanchard J. Selective induction of protective MHC class I-restricted CTL in the intestinal lamina propria of rhesus monkeys by transient SIV infection of the colonic mucosa. J. Immunol. 162:1999;540-549.
37. Ogg G. S., Jin X., Bonhoeffer S., Moss P., Nowak M. A., Monard S., Segal J. P., Cao Y., Rowland-Jones S. L., Hurley A., Markowitz M., Ho D. D., McMichael A. J., Nixon D. F. Decay kinetics of human immunodeficiency virus-specific effector cytotoxic T lymphocytes after combination antiretroviral therapy. J. Virol. 73:1999;797-800.
38. Pope M. Mucosal dendritic cells and immunodeficiency viruses. J. Infect. Dis. 179:1999.
39. Ridge J. P., Di Rosa F., Matzinger P. A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell. Nature. 393:1998;474-478.
40. Sadat-Sowti B., Debre P., Mollet L., Quint L., Hadida F., Leblond V., Bismuth G., Autran B. An inhibitor of cytotoxic functions produced by CD8+CD57+ T lymphocytes from patients suffering from AIDS and immunosuppressed bone marrow recipients. Eur. J. Immunol. 24:1994;2882-2888.
41. Saito H., Kanamori Y., Takemori T., Nariuchi H., Kubota E., Takahashi-Iwanaga H., Iwanaga T., Ishikawa H. Generation of intestinal T cells from progenitors residing in gut cryptopatches. Science. 280:1998;275-278.
42. Schieferdecker H. L., Ullrich R., Weiss-Breckwoldt A. N., Schwarting R., Stein H., Riecken E. O., Zeitz M. The HML-1 antigen of intestinal lymphocytes is an activation antigen. J. Immunol. 144:1990;2541-2549.
43. Schneider T., Jahn H. U., Schmidt W., Riecken E. O., Zeitz M., Ullrich R. Loss of CD4 T lymphocytes in patients infected with human immunodeficiency virus type 1 is more pronounced in the duodenal mucosa than in the peripheral blood. Gut. 37:1995;524-529.
44. Schneider T., Ullrich R., Bergs C., Schmidt W., Riecken E. O., Zeitz M. Abnormalities in subset distribution, activation, and differentiation of T cells isolated from large intestine biopsies in HIV infection. Clin. Exp. Immunol. 95:1994;430-435.
45. Schoenberger S. P., Toes R. E., van der Voort E. I., Offringa R., Melief C. J. T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions. Nature. 393:1998;480-483.
46. Smith P. D., Fox C. H., Masur H., Winter H. S., Alling D. W. Quantitative analysis of mononuclear cells expressing human immunodeficiency virus type 1 RNA in esophageal mucosa. J. Exp. Med. 180:1994;1541-1546.
47. Spiegel H. M. L., Ogg G. S., DeFalcon E., Sheehy M. E., Monard S., Haslett P. A., Gillespie G., Donahoe S. M., Pollack H., Borkowsky W., McMichael A. J., Nixon D. F. Human immunodeficiency virus type 1- and cytomegalovirus-specific cytotoxic T lymphocytes can persist at high frequency for prolonged periods in the absence of circulating peripheral CD4(+) T cells. J. Virol. 74:2000;1018-1022.
48. Sydora B. C., Jamieson B. D., Ahmed R., Kronenberg M. Intestinal intraepithelial lymphocytes respond to systemic lymphocytic choriomeningitis virus infection. Cell Immunol. 167:1996;161-169.
49. Taplin M. E., Frantz M. E., Canning C., Ritz J., Blumberg R. S., Balk S. P. Evidence against T-cell development in the adult human intestinal mucosa based upon lack of terminal deoxynucleotidyltransferase expression. Immunology. 87:1996;402-407.
50. Ullrich R., Schmidt W., Zippel T., Schneider T., Zeitz M., Riecken E. O. Mucosal HIV infection. Pathobiology. 66:1998;145-150.
51. Veazey R., DeMaria M., Chalifoux L., Shvetz D., Pauley D., Knight H., Rosenzweig M., Johnson R., Desrosiers R., Lackner A. Gastrointestinal tract as a major site of CD4+ T cell depletion and viral replication in SIV infection. Science. 280:1998;427-431.
52. + cells in human cytomegalovirus and other viral infections. Scand. J. Infect. Dis. Suppl. 99:1995;69-77.
53. Zeitz M., Schneider T., Ullrich R. Mucosal HIV infection: A paradigm for dysregulation of the mucosal immune system. Kagnoff M. Essentials of Mucosal Immunology. 1996;421 Academic Press, San Diego.