-
1
-
-
12444279265
-
On the origin of cancer cells
-
Warburg, O. (1956) On the origin of cancer cells. Science 123, 309-314.
-
(1956)
Science
, vol.123
, pp. 309-314
-
-
Warburg, O.1
-
2
-
-
33847367741
-
Energy metabolism in tumor cells
-
Moreno-Sánchez, R., Rodríguez-Enríquez, S., Marín-Hernández, A., and Saavedra, E. (2007) Energy metabolism in tumor cells. FEBS J. 274, 1393-1418.
-
(2007)
FEBS J.
, vol.274
, pp. 1393-1418
-
-
Moreno-Sánchez, R.1
Rodríguez-Enríquez, S.2
Marín-Hernández, A.3
Saavedra, E.4
-
3
-
-
0030884030
-
Overexpression of glucose transporter 1 and increased FDG uptake in pancreatic carcinoma
-
Reske, S. N., Grillenberger, K. G., Glatting, G., Port, M., Hildebrandt, M., Gansauge, F., and Beger, H. G. (1997) Overexpression of glucose transporter 1 and increased FDG uptake in pancreatic carcinoma. J. Nucl. Med. 38, 1344-1348.
-
(1997)
J. Nucl. Med.
, vol.38
, pp. 1344-1348
-
-
Reske, S.N.1
Grillenberger, K.G.2
Glatting, G.3
Port, M.4
Hildebrandt, M.5
Gansauge, F.6
Beger, H.G.7
-
4
-
-
0036077547
-
Glucose transporters: Expression, regulation and cancer
-
Medina, R. A., and Owen, G. I. (2002) Glucose transporters: expression, regulation and cancer. Biol. Res. 35, 9-26.
-
(2002)
Biol. Res.
, vol.35
, pp. 9-26
-
-
Medina, R.A.1
Owen, G.I.2
-
5
-
-
0032875964
-
Expression of facilitative glucose transporters in gastric tumors
-
Noguchi, Y., Marat, D., Saito, A., Yoshikawa, T., Doi, C., Fukuzawa, K., Tsubaraya, A., Satoh, S., and Ito, T. (1999) Expression of facilitative glucose transporters in gastric tumors. Hepatogastroenterology 46, 2683-2689.
-
(1999)
Hepatogastroenterology
, vol.46
, pp. 2683-2689
-
-
Noguchi, Y.1
Marat, D.2
Saito, A.3
Yoshikawa, T.4
Doi, C.5
Fukuzawa, K.6
Tsubaraya, A.7
Satoh, S.8
Ito, T.9
-
6
-
-
4644360172
-
Differential regulation of glucose transporter expression by estrogen and progesterone in Ishikawa endometrial cancer cells
-
Medina, R. A., Meneses, A. M., Vera, J. C., Guzmán, C., Nualart, F., Rodríguez, F.De los Angeles García, M., Kato, S., Espinoza, N., Monso, C., Carvajal, A., Pinto, M., and Owen, G. I. (2004) Differential regulation of glucose transporter expression by estrogen and progesterone in Ishikawa endometrial cancer cells. J. Endocrinol. 182, 467-478.
-
(2004)
J. Endocrinol.
, Issue.182
, pp. 467-478
-
-
Medina, R.A.1
Meneses, A.M.2
Vera, J.C.3
Guzmán, C.4
Nualart, F.5
Rodríguez, F.6
De Los Angeles García, M.7
Kato, S.8
Espinoza, N.9
Monso, C.10
Carvajal, A.11
Pinto, M.12
Owen, G.I.13
-
7
-
-
48349138947
-
Expression analysis of facilitative glucose transporters (GLUTs) in human tyroid carcinoma call lines and primary tumors
-
Ciampi, R., Vivaldi, A., Romeo, C., Del Guerra, A., Salvadori, P., Cosci, B., Pinchera, A., and Elisei, R. (2008) Expression analysis of facilitative glucose transporters (GLUTs) in human tyroid carcinoma call lines and primary tumors. Mol. Cell. Endocrinol. 291, 57-62.
-
(2008)
Mol. Cell. Endocrinol.
, vol.291
, pp. 57-62
-
-
Ciampi, R.1
Vivaldi, A.2
Romeo, C.3
Del Guerra, A.4
Salvadori, P.5
Cosci, B.6
Pinchera, A.7
Elisei, R.8
-
8
-
-
36849066369
-
Regulation of GLUT3 and glucose uptake by the cAMP signaling pathway in the breast cancer cell line ZR-75
-
Meneses, A. M., Medina, R. A., Kato, S., Pinto, M., Jaque, M. P., Lizama, I., de L. García, M., Nualart, F., and Owen, G. I. (2008) Regulation of GLUT3 and glucose uptake by the cAMP signaling pathway in the breast cancer cell line ZR-75. J. Cell Physiol. 214, 110-116.
-
(2008)
J. Cell Physiol.
, vol.214
, pp. 110-116
-
-
Meneses, A.M.1
Medina, R.A.2
Kato, S.3
Pinto, M.4
Jaque, M.P.5
Lizama, I.6
De García, L.M.7
Nualart, F.8
Owen, G.I.9
-
9
-
-
38749126716
-
Significance of the glycolytic pathway and glycolysis related-genes in tumorigenesis of human colorectal cancers
-
Yeh, C. S., Wang, J. Y., Chung, F. Y., Lee, S. C., Huang, M. Y., Kuo, C. W., Yang, M. L., and Lin, S. R. (2008) Significance of the glycolytic pathway and glycolysis related-genes in tumorigenesis of human colorectal cancers. Oncol. Rep. 19, 81-91.
-
(2008)
Oncol. Rep.
, vol.19
, pp. 81-91
-
-
Yeh, C.S.1
Wang, J.Y.2
Chung, F.Y.3
Lee, S.C.4
Huang, M.Y.5
Kuo, C.W.6
Yang, M.L.7
Lin, S.R.8
-
10
-
-
33646266734
-
Determining and understanding the control of glycolysis in fast-growth tumor cells. Flux control by an over-expressed but strongly product-inhibited hexokinase
-
Marín-Hernández, A., Rodríguez-Enríquez, S., Vital-González, P. A., Flores-Rodríguez, F. L., Macias-Silva, M., Sosa-Garrocho, M., and Moreno-Sanchez, R. (2006) Determining and understanding the control of glycolysis in fast-growth tumor cells. Flux control by an over-expressed but strongly product-inhibited hexokinase. FEBS J. 273, 1975-1988.
-
(2006)
FEBS J.
, vol.273
, pp. 1975-1988
-
-
Marín-Hernández, A.1
Rodríguez-Enríquez, S.2
Vital-González, P.A.3
Flores-Rodríguez, F.L.4
MacIas-Silva, M.5
Sosa-Garrocho, M.6
Moreno-Sanchez, R.7
-
11
-
-
0017838819
-
Isoenzymes of hexokinase in the developing, normal and neoplastic human brain
-
Bennett, M. J., Timperley, W. R., Taylor, C. B., and Hill, A. S. (1978) Isoenzymes of hexokinase in the developing, normal and neoplastic human brain. Eur. J. Cancer 14, 189-193.
-
(1978)
Eur. J. Cancer
, vol.14
, pp. 189-193
-
-
Bennett, M.J.1
Timperley, W.R.2
Taylor, C.B.3
Hill, A.S.4
-
12
-
-
38949116279
-
Expression of glucose transporters and hexokinase II in cholangiocellular carcinoma compared using [18F]-2-fluoro-2-deoxy-D-glucose positron emission tomography
-
Paudyal, B., Oriuchi, N., Paudyal, P., Higuchi, T., Nakajima, T., and Endo, K. (2008) Expression of glucose transporters and hexokinase II in cholangiocellular carcinoma compared using [18F]-2-fluoro-2-deoxy-D-glucose positron emission tomography. Cancer Sci. 99, 260-266.
-
(2008)
Cancer Sci.
, vol.99
, pp. 260-266
-
-
Paudyal, B.1
Oriuchi, N.2
Paudyal, P.3
Higuchi, T.4
Nakajima, T.5
Endo, K.6
-
13
-
-
56749164865
-
2-[(18)F]-2-Deoxy-D-Glucose (FDG) uptake in human tumor cells is related to the expresson of GLUT-1 and hexokinase II
-
Ong, L. C., Jin, Y., Song, I. C., Yu, S., Zhang, K., and Chow, P. K. (2008) 2-[(18)F]-2-Deoxy-D-Glucose (FDG) uptake in human tumor cells is related to the expresson of GLUT-1 and hexokinase II. Acta Radiol. 49, 1145-1153.
-
(2008)
Acta Radiol.
, Issue.49
, pp. 1145-1153
-
-
Ong, L.C.1
Jin, Y.2
Song, I.C.3
Yu, S.4
Zhang, K.5
Chow, P.K.6
-
14
-
-
0021873592
-
Alterations in the activity and isozymic profile of human phosphofructokinase durig malignant transformation in vivo and in vitro: Transformation-and progression-linked discriminants of malignancy
-
Vora, S., Halper, J. P., and Knowles, D. M. (1985) Alterations in the activity and isozymic profile of human phosphofructokinase durig malignant transformation in vivo and in vitro: Transformation-and progression-linked discriminants of malignancy. Cancer Res. 45, 2993-3001.
-
(1985)
Cancer Res.
, vol.45
, pp. 2993-3001
-
-
Vora, S.1
Halper, J.P.2
Knowles, D.M.3
-
15
-
-
0025858924
-
Immunochemical and immunohistochemical studies on three aldolase isozymes in human lung cancer
-
Ojika, T., Imaizumi, M., Abe, T., and Kato, K. (1991) Immunochemical and immunohistochemical studies on three aldolase isozymes in human lung cancer. Cancer 67, 2153-2158.
-
(1991)
Cancer
, vol.67
, pp. 2153-2158
-
-
Ojika, T.1
Imaizumi, M.2
Abe, T.3
Kato, K.4
-
16
-
-
17844380283
-
Overexpression of alpha enolase in hepatitis C virus-related hepatocellular carcinoma: Association with tumor progression as determined by proteomic analysis
-
Takashima, M., Kuramitsu, Y., Yokoyama, Y., Iizuka, N., Fujimoto, M., Nishisaka, T., Okita, K., Oka, M., and Nakamura, K. (2005) Overexpression of alpha enolase in hepatitis C virus-related hepatocellular carcinoma: association with tumor progression as determined by proteomic analysis. Proteonomics 5, 1686-1692.
-
(2005)
Proteonomics
, vol.5
, pp. 1686-1692
-
-
Takashima, M.1
Kuramitsu, Y.2
Yokoyama, Y.3
Iizuka, N.4
Fujimoto, M.5
Nishisaka, T.6
Okita, K.7
Oka, M.8
Nakamura, K.9
-
17
-
-
33750285970
-
Identification of alpha-enolase as an autoantigen in lung cancer: Iits overexpression is associated with clinical outcomes
-
Chang, G. C., Liu, K. J., Hsieh, C. L., Hu, T. S., S.Charoenfuprasert, Liu, H. K., Luh, K. T., L.H.Hsu, C.W.Wu, Ting, C. C., Chen, C. Y., Chen, K. C., Yang, T. Y., Chou, T. Y., Wang, W. H., Whang-Peng, J., and Shih, N. Y. (2006) Identification of alpha-enolase as an autoantigen in lung cancer: its overexpression is associated with clinical outcomes. Clin. Cancer Res. 12, 5746-5754.
-
(2006)
Clin. Cancer Res.
, vol.12
, pp. 5746-5754
-
-
Chang, G.C.1
Liu, K.J.2
Hsieh, C.L.3
Hu, T.S.4
Charoenfuprasert, S.5
Liu, H.K.6
Luh, K.T.7
Hsu, L.H.8
Wu, C.W.9
Ting, C.C.10
Chen, C.Y.11
Chen, K.C.12
Yang, T.Y.13
Chou, T.Y.14
Wang, W.H.15
Whang-Peng, J.16
Shih, N.Y.17
-
18
-
-
34247860855
-
Expression of glycolytic enzymes is increased in pancreatic cancerous tissues as evidence by proteonomic profiling by two-dimensional electrophoresis
-
Mikuriya, K., Kuramitsu, Y., Ryozawa, S., Fujimoto, M., Mori, S., Oka, M., Hamano, K., Okita, K., Sakaida, I., and Nakamura, K. (2007) Expression of glycolytic enzymes is increased in pancreatic cancerous tissues as evidence by proteonomic profiling by two-dimensional electrophoresis. Int. J. Oncol. 30, 849-855.
-
(2007)
Int. J. Oncol.
, vol.30
, pp. 849-855
-
-
Mikuriya, K.1
Kuramitsu, Y.2
Ryozawa, S.3
Fujimoto, M.4
Mori, S.5
Oka, M.6
Hamano, K.7
Okita, K.8
Sakaida, I.9
Nakamura, K.10
-
19
-
-
0036262039
-
Low mitochondrial respiratory chain content correlates with tumor aggressiveness in renal cell carcinoma
-
Simmonet, H., Alazard, N., Pfeiffer, K., Gallou, C., C.Béroud, Demont, J., Bouvier, R., Schagger, H., and Godinot, C. (2002) Low mitochondrial respiratory chain content correlates with tumor aggressiveness in renal cell carcinoma. Carcinogenesis 23, 759-768.
-
(2002)
Carcinogenesis
, vol.23
, pp. 759-768
-
-
Simmonet, H.1
Alazard, N.2
Pfeiffer, K.3
Gallou, C.4
Béroud, C.5
Demont, J.6
Bouvier, R.7
Schagger, H.8
Godinot, C.9
-
20
-
-
33750202160
-
Association of decreased mitochondrial DNA content with ovarian cancer progression
-
Wang, Y., Liu, V. W., Xue, W. C., Cheung, A. N., and Ngan, H. Y. (2006) Association of decreased mitochondrial DNA content with ovarian cancer progression. Br. J. Cancer 95, 1087-1091.
-
(2006)
Br. J. Cancer
, vol.95
, pp. 1087-1091
-
-
Wang, Y.1
Liu, V.W.2
Xue, W.C.3
Cheung, A.N.4
Ngan, H.Y.5
-
21
-
-
34547509586
-
Transformation of human mesenchymal stem cells increases their dependency on oxidative phosphorylation for energy production
-
Funes, J., Quintero, M., Henderson, S., Martinez, D., Qureshi, U., Westwood, C., Clements, M. O., Bourboulia, D., Pedley, R. B., Moncada, S., and Boshoff, C. (2007) Transformation of human mesenchymal stem cells increases their dependency on oxidative phosphorylation for energy production. Proc. Natl. Acad. Sci. USA 104, 6223-6228.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 6223-6228
-
-
Funes, J.1
Quintero, M.2
Henderson, S.3
Martinez, D.4
Qureshi, U.5
Westwood, C.6
Clements, M.O.7
Bourboulia, D.8
Pedley, R.B.9
Moncada, S.10
Boshoff, C.11
-
22
-
-
33746891176
-
Mitochondrial DNA mutations in human cancer
-
Chatterjee, A., Mambo, E., and Sidransky, D. (2006) Mitochondrial DNA mutations in human cancer. Oncogene 25, 4663-4674.
-
(2006)
Oncogene
, vol.25
, pp. 4663-4674
-
-
Chatterjee, A.1
Mambo, E.2
Sidransky, D.3
-
23
-
-
19944433653
-
Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase
-
Selak, M. A., Armour, S. M., MacKenzie, E. D., Boulahbel, H., Watson, D. G., Mansfield, K. D., Pan, Y., Simon, M. C., Thompson, C. B., and Gottlieb, E. (2005) Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase. Cancer Cell. 7, 77-85.
-
(2005)
Cancer Cell.
, vol.7
, pp. 77-85
-
-
Selak, M.A.1
Armour, S.M.2
MacKenzie, E.D.3
Boulahbel, H.4
Watson, D.G.5
Mansfield, K.D.6
Pan, Y.7
Simon, M.C.8
Thompson, C.B.9
Gottlieb, E.10
-
24
-
-
26444570010
-
Accumulation of Krebs cycle intermediates and overexpression of HIF1alpha in tumours which result from germline FH and SDH mutations
-
Pollard, P. J., Briere, J. J., Alam, N. A., Barwell, J., Barclay, E., Wortham, N. C., Hunt, T., Mitchell, M., Olpin, S., Moat, S. J., Hargreaves, I. P., Heales, S. J., Chung, Y. L., Griffiths, J. R., Dalgleish, A., MacGrath, J. A., Gleeson, M. J., Hodgson, S. V., Puolsom, R., Rustin, P., and Tomlinson, I. P. (2005) Accumulation of Krebs cycle intermediates and overexpression of HIF1alpha in tumours which result from germline FH and SDH mutations. Hum. Mol. Genet. 14, 2231-2239.
-
(2005)
Hum. Mol. Genet.
, vol.14
, pp. 2231-2239
-
-
Pollard, P.J.1
Briere, J.J.2
Alam, N.A.3
Barwell, J.4
Barclay, E.5
Wortham, N.C.6
Hunt, T.7
Mitchell, M.8
Olpin, S.9
Moat, S.J.10
Hargreaves, I.P.11
Heales, S.J.12
Chung, Y.L.13
Griffiths, J.R.14
Dalgleish, A.15
MacGrath, J.A.16
Gleeson, M.J.17
Hodgson, S.V.18
Puolsom, R.19
Rustin, P.20
Tomlinson, I.P.21
more..
-
25
-
-
0035003072
-
Mitochondrial DNA in human malignancy
-
Penta, J. S., Johnson, F. M., Wachsman, J. T., and Copeland, W.C. (2001) Mitochondrial DNA in human malignancy. Mutat. Res. 488, 119-133.
-
(2001)
Mutat. Res.
, vol.488
, pp. 119-133
-
-
Penta, J.S.1
Johnson, F.M.2
Wachsman, J.T.3
Copeland, W.C.4
-
26
-
-
12244257553
-
Understanding the tumor-metabolic phenotype in the genomic era
-
Stubbs, M., Bashford, C. L., and Griffiths, J. R. (2003) Understanding the tumor-metabolic phenotype in the genomic era. Curr. Mol. Med. 3, 49-59.
-
(2003)
Curr. Mol. Med.
, vol.3
, pp. 49-59
-
-
Stubbs, M.1
Bashford, C.L.2
Griffiths, J.R.3
-
27
-
-
0021327015
-
Enzyme activities in normal, dysplastic, and cancerous human breast tissues
-
Balinsky, D., Platz, C. E., and Lewis, J. W. (1984) Enzyme activities in normal, dysplastic, and cancerous human breast tissues. J. Natl. Cancer. Inst. 72, 217-224.
-
(1984)
J. Natl. Cancer. Inst.
, vol.72
, pp. 217-224
-
-
Balinsky, D.1
Platz, C.E.2
Lewis, J.W.3
-
29
-
-
7944226627
-
Genes of glycolysis are ubiquitously overexpressed in 24 cancer classes
-
Altenberg, B., and Greulich, K. O. (2004) Genes of glycolysis are ubiquitously overexpressed in 24 cancer classes. Genomics 84, 1014-1020.
-
(2004)
Genomics
, vol.84
, pp. 1014-1020
-
-
Altenberg, B.1
Greulich, K.O.2
-
30
-
-
18644366801
-
Hypoxia-inducible factor-1a and the glycolytic phenotype in tumors
-
Robey, I. F., Lien, A. D., Welsh, S. J., Baggett, B. K., and Gillie, R. J. (2005) Hypoxia-inducible factor-1a and the glycolytic phenotype in tumors. Neoplasia 7, 324-330.
-
(2005)
Neoplasia
, vol.7
, pp. 324-330
-
-
Robey, I.F.1
Lien, A.D.2
Welsh, S.J.3
Baggett, B.K.4
Gillie, R.J.5
-
31
-
-
0034676331
-
Up-regulation of hypoxia-inducible factors HIF-1alpha and HIF-2alpha under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function
-
Krieg, M., Haas, R., Brauch, H., Acker, T., Flamme, I., and Plate, K. H. (2000) Up-regulation of hypoxia-inducible factors HIF-1alpha and HIF-2alpha under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function. Oncogene 19, 5435-5443.
-
(2000)
Oncogene
, vol.19
, pp. 5435-5443
-
-
Krieg, M.1
Haas, R.2
Brauch, H.3
Acker, T.4
Flamme, I.5
Plate, K.H.6
-
32
-
-
33644622570
-
HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption
-
Papandreou, I., Cairns, R. A., Fontana, L., Lim, A. L., and Denko, N. C. (2006) HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption. Cell. Metab. 3, 187-197.
-
(2006)
Cell. Metab.
, vol.3
, pp. 187-197
-
-
Papandreou, I.1
Cairns, R.A.2
Fontana, L.3
Lim, A.L.4
Denko, N.C.5
-
33
-
-
33644614520
-
HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia
-
Kim, J. W., Tchernyshyov, I., Semenza, G. L., and Dang, C. V. (2006) HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia. Cell. Metab,3, 177-185.
-
(2006)
Cell. Metab
, vol.3
, pp. 177-185
-
-
Kim, J.W.1
Tchernyshyov, I.2
Semenza, G.L.3
Dang, C.V.4
-
34
-
-
53049087909
-
Pyruvate dehydrogenase complex activity controls metabolic and malignant phenotype in cancer cells
-
McFate, T., Mohyeldin, A., Lu, H., Thakar, J., J.Henriques, Halim, N. D., Wu, H., Schell, M. J., Tsang, T. M., Teahan, O., Zhou, S., Califano, J. A., Jeoung, N. H., Harris, R. A., and Verma, A. (2008) Pyruvate dehydrogenase complex activity controls metabolic and malignant phenotype in cancer cells. J. Biol. Chem. 283, 22700-22708.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 22700-22708
-
-
McFate, T.1
Mohyeldin, A.2
Lu, H.3
Thakar, J.4
Henriques, J.5
Halim, N.D.6
Wu, H.7
Schell, M.J.8
Tsang, T.M.9
Teahan, O.10
Zhou, S.11
Califano, J.A.12
Jeoung, N.H.13
Harris, R.A.14
Verma, A.15
-
35
-
-
33846002728
-
+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth
-
+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth. Cancer Cell. 11, 37-51.
-
(2007)
Cancer Cell.
, vol.11
, pp. 37-51
-
-
Bonnet, S.1
Archer, S.L.2
Allalunis-Turner, J.3
Haromy, A.4
Beaulieu, C.5
Thompson, R.6
Lee, C.T.7
Lopaschuk, G.D.8
Puttagunta, L.9
Bonnet, S.10
Harry, G.11
Hashimoto, K.12
Porter, C.J.13
Andrade, M.A.14
Thebaud, B.15
Michelakis, E.D.16
-
36
-
-
0034698178
-
Deregulation of glucose transporter 1 and glycolytic gene expression by c-Myc
-
Osthus, R. C., Shim, H., Kim, S., Li, Q., Reddy, R., Mukherjee, M., Xu, Y., Wonsey, D., Lee, L. A., and Dang, C. V. (2000) Deregulation of glucose transporter 1 and glycolytic gene expression by c-Myc. J. Biol. Chem. 29, 21797-21800.
-
(2000)
J. Biol. Chem.
, vol.29
, pp. 21797-21800
-
-
Osthus, R.C.1
Shim, H.2
Kim, S.3
Li, Q.4
Reddy, R.5
Mukherjee, M.6
Xu, Y.7
Wonsey, D.8
Lee, L.A.9
Dang, C.V.10
-
37
-
-
35649014840
-
Hypoxia-inducible factor 1 and dysregulated c-Myc cooperatively induce vascular endothelial growth factor and metabolic switches hexokinase 2 and pyruvate dehydrogenase kinase 1
-
Kim, J. W., Gao, P., Liu, Y. C., Semenza, G. L., and Dang, C. V. (2007) Hypoxia-inducible factor 1 and dysregulated c-Myc cooperatively induce vascular endothelial growth factor and metabolic switches hexokinase 2 and pyruvate dehydrogenase kinase 1. Mol. Cell. Biol. 27, 7381-7391.
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 7381-7391
-
-
Kim, J.W.1
Gao, P.2
Liu, Y.C.3
Semenza, G.L.4
Dang, C.V.5
-
38
-
-
34247136256
-
Metabolic enzymes regulated by the Myc oncogene are possible targets for chemotherapy or chemoprevention
-
Rimpi, S., and Nilsson, J. A. (2007) Metabolic enzymes regulated by the Myc oncogene are possible targets for chemotherapy or chemoprevention. Biochem. Soc. Trans. 35, 305-310.
-
(2007)
Biochem. Soc. Trans.
, vol.35
, pp. 305-310
-
-
Rimpi, S.1
Nilsson, J.A.2
-
39
-
-
21744442902
-
Myc stimulates nuclearly encoded mitochondrial genes and mitochondrial biogenesis
-
Li, F., Wang, Y., Keller, K. I., Potter, J. J., Wonsey, D. R., O'Donnell, K. A., Kim, J. W., Yustein, J. T., Lee, L. A., and Dang, C. V. (2005) Myc stimulates nuclearly encoded mitochondrial genes and mitochondrial biogenesis. Mol. Cell. Biol. 25, 6225-6234.
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 6225-6234
-
-
Li, F.1
Wang, Y.2
Keller, K.I.3
Potter, J.J.4
Wonsey, D.R.5
O'donnell, K.A.6
Kim, J.W.7
Yustein, J.T.8
Lee, L.A.9
Dang, C.V.10
-
40
-
-
0344009714
-
C-Myc overexpression sensitizes colon cancer cells to camptothecin-induced apoptosis
-
Arango, D., Mariadson, J. M., Wilson, A. J., Yang, W., Corner, G. A., Nicholas, C., Aranes, M. J., and Augenlicht, L. H. (2003) c-Myc overexpression sensitizes colon cancer cells to camptothecin-induced apoptosis. Br. J. Cancer 89, 1757-1765.
-
(2003)
Br. J. Cancer
, vol.89
, pp. 1757-1765
-
-
Arango, D.1
Mariadson, J.M.2
Wilson, A.J.3
Yang, W.4
Corner, G.A.5
Nicholas, C.6
Aranes, M.J.7
Augenlicht, L.H.8
-
41
-
-
0037424347
-
Astroglial c-Myc overexpression predisposes mice to primary malignant gliomas
-
Jensen, N. A., Pedersen, K. M., Lihme, F., Rask, L., Nielsen, J. V., Rasmussen, T. E., and Mitchelmore, C. (2003) Astroglial c-Myc overexpression predisposes mice to primary malignant gliomas. J. Biol. Chem. 278, 8300-8308.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 8300-8308
-
-
Jensen, N.A.1
Pedersen, K.M.2
Lihme, F.3
Rask, L.4
Nielsen, J.V.5
Rasmussen, T.E.6
Mitchelmore, C.7
-
42
-
-
0033551374
-
MYC oncogenes and human neoplastic diseases
-
Nesbit, C. E., Tersak, J. M., and Prochownik, E. V. (1999) MYC oncogenes and human neoplastic diseases. Oncogene 18, 3004-3016.
-
(1999)
Oncogene
, vol.18
, pp. 3004-3016
-
-
Nesbit, C.E.1
Tersak, J.M.2
Prochownik, E.V.3
-
43
-
-
73249139900
-
Regulation of the Warburg effect in earlypassage breast cancer cells
-
Robey, I. F., Stephen, R. M., Brown, K. S., Baggett, B. K., Gatenby, R. A., and Gillies, R. J. (2008) Regulation of the Warburg effect in earlypassage breast cancer cells. Mol. Cell. Biol. 27, 7381-7393.
-
(2008)
Mol. Cell. Biol.
, vol.27
, pp. 7381-7393
-
-
Robey, I.F.1
Stephen, R.M.2
Brown, K.S.3
Baggett, B.K.4
Gatenby, R.A.5
Gillies, R.J.6
-
44
-
-
0017306757
-
The regulatory principles of glycolysis in erythrocytes in vivo and in vitro. A minimal comprehensive model describing steady states, quasi-steady states and time-dependent processes
-
Rapoport, T. A., Heinrich, R., and Rapoport, S. M. (1976) The regulatory principles of glycolysis in erythrocytes in vivo and in vitro. A minimal comprehensive model describing steady states, quasi-steady states and time-dependent processes. Biochem. J. 154, 449-469.
-
(1976)
Biochem. J.
, vol.154
, pp. 449-469
-
-
Rapoport, T.A.1
Heinrich, R.2
Rapoport, S.M.3
-
45
-
-
0022499217
-
Kinetics of metabolic pathways
-
Torres, N. V., Mateo, F., Meléndez-Hevia, E., and Kacser, H. (1986) Kinetics of metabolic pathways. Biochem. J. 234, 169-174.
-
(1986)
Biochem. J.
, vol.234
, pp. 169-174
-
-
Torres, N.V.1
Mateo, F.2
Meléndez-Hevia, E.3
Kacser, H.4
-
46
-
-
0024327322
-
Study of flux and transition time control coefficient profiles in a metabolic system in vitro and the effect of an external stimulator
-
Torres, N. V., Souto, R., and Meléndez-Hevia, E. (1989) Study of flux and transition time control coefficient profiles in a metabolic system in vitro and the effect of an external stimulator. Biochem. J. 260, 763-769.
-
(1989)
Biochem. J.
, vol.260
, pp. 763-769
-
-
Torres, N.V.1
Souto, R.2
Meléndez-Hevia, E.3
-
47
-
-
0027970353
-
Control of glucose utilization in working perfused rat heart
-
Kashiwaya, Y. K., Sato, K., Tsuchiya, N., Thomas, S., Fell, D. A., Veech, R. L., and Passonneau, J. V. (1994) Control of glucose utilization in working perfused rat heart. J. Biol. Chem. 269, 25502-25514.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 25502-25514
-
-
Kashiwaya, Y.K.1
Sato, K.2
Tsuchiya, N.3
Thomas, S.4
Fell, D.A.5
Veech, R.L.6
Passonneau, J.V.7
-
48
-
-
0029926785
-
Expression of the fructose transporter GLUT5 in human breast cancer
-
Zamora-León, S. P., Golde, D. W., Concha, I. I., Rivas, C. I., Delgado-López, F., Baselga, J., Nualart, F., and Vera, J. C. (1996) Expression of the fructose transporter GLUT5 in human breast cancer. Proc. Natl. Acad. Sci. USA 93, 1847-1852.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 1847-1852
-
-
Zamora-León, S.P.1
Golde, D.W.2
Concha, I.I.3
Rivas, C.I.4
Delgado-López, F.5
Baselga, J.6
Nualart, F.7
Vera, J.C.8
-
49
-
-
0035130377
-
Glut1 expression in T1 and T2 stage colorectal carcinomas: Its relationship to clinicopathological features
-
Sakashita, M., Aoyama, N., Minami, R., Maekawa, S., Kuroda, K., Shirasaka, D., Ichihara, T., Kuroda, Y., Maeda, S., and Kasuga, M. (2001) Glut1 expression in T1 and T2 stage colorectal carcinomas: its relationship to clinicopathological features. Eur. J. Cancer 37, 204-209.
-
(2001)
Eur. J. Cancer
, vol.37
, pp. 204-209
-
-
Sakashita, M.1
Aoyama, N.2
Minami, R.3
Maekawa, S.4
Kuroda, K.5
Shirasaka, D.6
Ichihara, T.7
Kuroda, Y.8
Maeda, S.9
Kasuga, M.10
-
50
-
-
0242332098
-
GLUT1 messenger RNA and protein induction relates to the malignant transformation of cervical cancer
-
Rudlowski, C., Becker, A. J., Schroder, W., Rath, W., Buttner, R., and Moser, M. (2003) GLUT1 messenger RNA and protein induction relates to the malignant transformation of cervical cancer. Am. J. Clin. Pathol. 120, 691-698.
-
(2003)
Am. J. Clin. Pathol.
, vol.120
, pp. 691-698
-
-
Rudlowski, C.1
Becker, A.J.2
Schroder, W.3
Rath, W.4
Buttner, R.5
Moser, M.6
-
51
-
-
0037056002
-
Mitochondrial bound type II hexokinase
-
Pedersen, P. L., Mathupala, S., Rempel, A., Geschwind, J. F., and Ko, Y. H. (2002) Mitochondrial bound type II hexokinase. Biochim. Biophys. Acta 1555, 14-20.
-
(2002)
Biochim. Biophys. Acta
, vol.1555
, pp. 14-20
-
-
Pedersen, P.L.1
Mathupala, S.2
Rempel, A.3
Geschwind, J.F.4
Ko, Y.H.5
-
52
-
-
0038714272
-
Isozymes of mammalian hexokinase: Structure, subcellular localization and metabolic function
-
Wilson, J. E. (2003) Isozymes of mammalian hexokinase: structure, subcellular localization and metabolic function. J. Exp. Biol. 206, 2049-2057.
-
(2003)
J. Exp. Biol.
, vol.206
, pp. 2049-2057
-
-
Wilson, J.E.1
-
53
-
-
0037099685
-
Novel therapy for liver cancer: Direct intraarterial injection of a potent inhibitor of ATP production
-
Geschwind, J. F., Ko, Y. H., Torbenson, M. S., Magee, C., and Pedersen, P. L. (2002) Novel therapy for liver cancer: direct intraarterial injection of a potent inhibitor of ATP production. Cancer Res. 62, 3909-3913.
-
(2002)
Cancer Res.
, vol.62
, pp. 3909-3913
-
-
Geschwind, J.F.1
Ko, Y.H.2
Torbenson, M.S.3
Magee, C.4
Pedersen, P.L.5
-
54
-
-
12544256565
-
Inhibition of glycolysis in cancer cells: A novel strategy to overcome drug resistance associated with mitochondrial respiratory defect and hypoxia
-
Xu, R., Pelicano, H., Zhou, Y., Carew, J. S., Feng, L., Bhalla, K. N., Keating, M. J., and Huang, P. (2005) Inhibition of glycolysis in cancer cells: A novel strategy to overcome drug resistance associated with mitochondrial respiratory defect and hypoxia. Cancer Res. 65, 613-621.
-
(2005)
Cancer Res.
, vol.65
, pp. 613-621
-
-
Xu, R.1
Pelicano, H.2
Zhou, Y.3
Carew, J.S.4
Feng, L.5
Bhalla, K.N.6
Keating, M.J.7
Huang, P.8
-
55
-
-
59849092584
-
Inhibition of energy-producing pathways of HepG2 cells by 3-bromopyruvate1
-
A.PPereira da Silva, El-Bacha, T., Kyaw, N., Sousa dos Santos, R., Seixas da-Silva, W., Almeida, F. C. L., Da Poian, A. T., and Galina, A. (2009) Inhibition of energy-producing pathways of HepG2 cells by 3-bromopyruvate1. Biochem. J. 417, 717-726.
-
(2009)
Biochem. J.
, Issue.417
, pp. 717-726
-
-
Pereira Da Silva, A.P.1
El-Bacha, T.2
Kyaw, N.3
Sousa Dos Santos, R.4
Seixas Da-Silva, W.5
Almeida, F.C.L.6
Da Poian, A.T.7
Galina, A.8
-
56
-
-
65549093967
-
Targeting of cancer energy metabolism
-
Rodríguez-Enríquez, S., Marín-Hernández, A., Gallardo-Pérez, J. C., Carreño-Fuentes, L., and Moreno-Sánchez, R. (2009) Targeting of cancer energy metabolism. Mol. Nutr. Food Res. 53, 29-48.
-
(2009)
Mol. Nutr. Food Res.
, vol.53
, pp. 29-48
-
-
Rodríguez-Enríquez, S.1
Marín-Hernández, A.2
Gallardo-Pérez, J.C.3
Carreño-Fuentes, L.4
Moreno-Sánchez, R.5
-
57
-
-
0040697067
-
Analysis of phosphofructokinase subunits and isozymes in ascites tumor cells and its original tissue, murine mammary gland
-
Sánchez-Martínez, C., and Aragón, J. J. (1997) Analysis of phosphofructokinase subunits and isozymes in ascites tumor cells and its original tissue, murine mammary gland. FEBS Lett. 133, 86-90.
-
(1997)
FEBS Lett.
, vol.133
, pp. 86-90
-
-
Sánchez-Martínez, C.1
Aragón, J.J.2
-
58
-
-
0023918653
-
Analysis of the phosphofructokinase subunits and isoenzymes in human tissues
-
Dunaway, G. A., Kasten, T. P., Sebo, T., and Trapp, R. (1988) Analysis of the phosphofructokinase subunits and isoenzymes in human tissues. Biochem. J. 251, 677-683.
-
(1988)
Biochem. J.
, vol.251
, pp. 677-683
-
-
Dunaway, G.A.1
Kasten, T.P.2
Sebo, T.3
Trapp, R.4
-
59
-
-
0342656636
-
Phosphofructokinase c isozyme from ascites tumor cells: Cloning, expression, and properties
-
Sánchez-Martínez, C., Estévez, A. M., and Aragón, J. J. (2000) Phosphofructokinase c isozyme from ascites tumor cells: cloning, expression, and properties. Biochem. Biophys. Res. Commun. 271, 635-640.
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.271
, pp. 635-640
-
-
Sánchez-Martínez, C.1
Estévez, A.M.2
Aragón, J.J.3
-
60
-
-
0021971417
-
Isozymic composition and regulatory properties of phosphofructokinase from well-differentiated and anaplastic medullary thyroid carcinomas of the rat
-
Oskam, R., Rijksen, G., Staal, G. E. J., and Vora, S. (1985) Isozymic composition and regulatory properties of phosphofructokinase from well-differentiated and anaplastic medullary thyroid carcinomas of the rat. Cancer Res. 45, 135-142.
-
(1985)
Cancer Res.
, vol.45
, pp. 135-142
-
-
Oskam, R.1
Rijksen, G.2
Staal, G.E.J.3
Vora, S.4
-
61
-
-
0023233164
-
Subunit composition, regulatory properties, and phosphorylation of phosphofructokinase from human gliomas
-
Staal, G. E. J., Kalff, A., Heesbeen, E. C., van Veelen, C. W. M., and Rijksen, G. (1987) Subunit composition, regulatory properties, and phosphorylation of phosphofructokinase from human gliomas. Cancer Res. 47, 5047-5051.
-
(1987)
Cancer Res.
, vol.47
, pp. 5047-5051
-
-
Staal, G.E.J.1
Kalff, A.2
Heesbeen, E.C.3
Van Veelen, C.W.M.4
Rijksen, G.5
-
62
-
-
23944498840
-
Lactate dehydrogenase 5 (LDH5) relates to up-regulated hypoxia inducible factor pathway and metastasis
-
Koukourakis, M. I., Giatromanolaki, A., Simopoulos, C., Polychronidis, A., and Sivridis, E. E. (2005) Lactate dehydrogenase 5 (LDH5) relates to up-regulated hypoxia inducible factor pathway and metastasis. Clin. Exp. Metastasis. 22, 25-30.
-
(2005)
Clin. Exp. Metastasis.
, vol.22
, pp. 25-30
-
-
Koukourakis, M.I.1
Giatromanolaki, A.2
Simopoulos, C.3
Polychronidis, A.4
Sivridis, E.E.5
-
63
-
-
33744783432
-
Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance
-
Fantin, V. R., St-Pierre, J., and Leder, P. (2006) Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance. Cancer Cell. 9, 425-434.
-
(2006)
Cancer Cell.
, vol.9
, pp. 425-434
-
-
Fantin, V.R.1
St-Pierre, J.2
Leder, P.3
-
64
-
-
0030921103
-
C-Myc transactivation of LDHA: Implications for tumor metabolism and growth
-
Shim, H., Dolde, C., Lewis, B. C., Wu, C. S., Dang, G., Jungmann, R. A., Dalla-Favera, R., and Dang, C. V. (1997) c-Myc transactivation of LDHA: implications for tumor metabolism and growth. Proc. Natl. Acad. Sci. USA 94, 6658-6663.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 6658-6663
-
-
Shim, H.1
Dolde, C.2
Lewis, B.C.3
Wu, C.S.4
Dang, G.5
Jungmann, R.A.6
Dalla-Favera, R.7
Dang, C.V.8
-
65
-
-
57449097020
-
Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice
-
Sonveaux, P., Végran, F., Schroeder, T., Wergin, M. C., Verrax, J., Rabbani, Z. N., De Saedeleer, C. J., Kennedy, K. M., Diepart, C., Jordan, B. F., Kelley, M. J., Gallez, B., Wahl, M. L., Feron, O., and Dewhirst, M. W. (2008) Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice. J. Clin. Invest. 118, 3930-3942.
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 3930-3942
-
-
Sonveaux, P.1
Végran, F.2
Schroeder, T.3
Wergin, M.C.4
Verrax, J.5
Rabbani, Z.N.6
De Saedeleer, C.J.7
Kennedy, K.M.8
Diepart, C.9
Jordan, B.F.10
Kelley, M.J.11
Gallez, B.12
Wahl, M.L.13
Feron, O.14
Dewhirst, M.W.15
-
66
-
-
0017841405
-
Tumor mitochondria and the bioenergetics of cancer cells
-
Pedersen, P. L. (1978) Tumor mitochondria and the bioenergetics of cancer cells. Prog. Exp. Tumor Res. 22, 190-274.
-
(1978)
Prog. Exp. Tumor Res.
, vol.22
, pp. 190-274
-
-
Pedersen, P.L.1
-
67
-
-
33644606491
-
Tracker dyes to probe mitochondrial autophagy (mitophagy) in rat hepatocytes
-
Rodríguez-Enríquez, S., Kim, I., Currin, R. T., and Lemasters, J. J. (2006) Tracker dyes to probe mitochondrial autophagy (mitophagy) in rat hepatocytes. Autophagy 2, 39-46.
-
(2006)
Autophagy
, vol.2
, pp. 39-46
-
-
Rodríguez-Enríquez, S.1
Kim, I.2
Currin, R.T.3
Lemasters, J.J.4
-
68
-
-
34247614521
-
HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of c-Myc activity
-
Zhang, H., Gao, P., Fukuda, R., Kumar, G., Krishnamachary, B., Zeller, K. I., Dang, C. V., and Semenza, D. L. (2007) HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of c-Myc activity. Cancer Cell. 11, 407-420.
-
(2007)
Cancer Cell.
, vol.11
, pp. 407-420
-
-
Zhang, H.1
Gao, P.2
Fukuda, R.3
Kumar, G.4
Krishnamachary, B.5
Zeller, K.I.6
Dang, C.V.7
Semenza, D.L.8
-
69
-
-
34547218569
-
Reduced mitochondrial DNA copy number is correlated with tumor progression and prognosis in Chinese breast cancer patients
-
Yu, M., Zhou, Y., Shi, Y., Ning, L., Yang, Y., Wei, X., Zhang, N., Hao, X., and Niu, R. (2007) Reduced mitochondrial DNA copy number is correlated with tumor progression and prognosis in Chinese breast cancer patients. IUBMB Life 59, 450-457.
-
(2007)
IUBMB Life
, vol.59
, pp. 450-457
-
-
Yu, M.1
Zhou, Y.2
Shi, Y.3
Ning, L.4
Yang, Y.5
Wei, X.6
Zhang, N.7
Hao, X.8
Niu, R.9
-
70
-
-
0036155472
-
Bronchial carcinoid tumor with crystalloid cytoplasmic inclusions
-
Grogg, K. L., Padmalatha, C., and Leslie, K. O. (2002) Bronchial carcinoid tumor with crystalloid cytoplasmic inclusions. Arch. Pathol. Lab. Med. 126, 93-96.
-
(2002)
Arch. Pathol. Lab. Med.
, vol.126
, pp. 93-96
-
-
Grogg, K.L.1
Padmalatha, C.2
Leslie, K.O.3
-
71
-
-
0017062424
-
Alteration of mitochondrial function and lipid composition in Morris 7777 hepatoma
-
Morton, R., Cunningham, C., Jester, R., Waite, M., Miller, N., and Morris, H. P. (1976) Alteration of mitochondrial function and lipid composition in Morris 7777 hepatoma. Cancer Res. 36, 3246-3254.
-
(1976)
Cancer Res.
, vol.36
, pp. 3246-3254
-
-
Morton, R.1
Cunningham, C.2
Jester, R.3
Waite, M.4
Miller, N.5
Morris, H.P.6
-
72
-
-
33745918951
-
TIGAR, a p53-inducible regulator of glycolysis and apoptosis
-
Besaad, K., Tsuruta, A., Selak, M. A., Vidal, M. N., Nakano, K., Bartrons, R., Gottlieb, E., and Vousden, K. H. (2006) TIGAR, a p53-inducible regulator of glycolysis and apoptosis. Cell 126, 8180-8187.
-
(2006)
Cell
, vol.126
, pp. 8180-8187
-
-
Besaad, K.1
Tsuruta, A.2
Selak, M.A.3
Vidal, M.N.4
Nakano, K.5
Bartrons, R.6
Gottlieb, E.7
Vousden, K.H.8
-
73
-
-
33745149291
-
P53 regulates mitochondrial respiration
-
Matoba, S., Kang, J. G., Patino, W. D., Wragg, A., Boehm, M., Gavrilova, O., Hurley, P. J., Bunz, F., and Hwang, P. M. (2006) p53 regulates mitochondrial respiration. Science 312, 1650-1653.
-
(2006)
Science
, vol.312
, pp. 1650-1653
-
-
Matoba, S.1
Kang, J.G.2
Patino, W.D.3
Wragg, A.4
Boehm, M.5
Gavrilova, O.6
Hurley, P.J.7
Bunz, F.8
Hwang, P.M.9
-
74
-
-
11244347171
-
Glycolytic enzymes can modulate life span
-
Kondoh, H., Lleonart, M. E., Gil, J., Wang, J., Degan, P., Peters, G., Martinez, D., Carnero, A., and Beach, D. (2005) Glycolytic enzymes can modulate life span. Cancer Res. 65, 177-185.
-
(2005)
Cancer Res.
, vol.65
, pp. 177-185
-
-
Kondoh, H.1
Lleonart, M.E.2
Gil, J.3
Wang, J.4
Degan, P.5
Peters, G.6
Martinez, D.7
Carnero, A.8
Beach, D.9
-
75
-
-
34547577319
-
P53 and its isoforms in cancer
-
Bourdon, J. C. (2007) p53 and its isoforms in cancer. Br. J. Cancer 97, 277-282.
-
(2007)
Br. J. Cancer
, vol.97
, pp. 277-282
-
-
Bourdon, J.C.1
-
76
-
-
44449147036
-
Tumor cell metabolism: Cancer's Achilles'Heel
-
Kroemer, G., and Pouyssegur, J. (2008) Tumor cell metabolism: Cancer's Achilles'Heel. Cancer Cell. 13, 472-482.
-
(2008)
Cancer Cell.
, vol.13
, pp. 472-482
-
-
Kroemer, G.1
Pouyssegur, J.2
-
77
-
-
33746466098
-
Mitochondrial mutations in cancer
-
Brandon, M., Baldi, P., and Wallace, D. C. (2006) Mitochondrial mutations in cancer. Oncogene 25, 4647-4662.
-
(2006)
Oncogene
, vol.25
, pp. 4647-4662
-
-
Brandon, M.1
Baldi, P.2
Wallace, D.C.3
-
78
-
-
28544446058
-
Mitochondrial tumour suppresors: A genetic and biochemical update
-
Gottlieb, E., and Tomlinson, I.P. M. (2005) Mitochondrial tumour suppresors: a genetic and biochemical update. Nat. Rev. Cancer 5, 857-866.
-
(2005)
Nat. Rev. Cancer
, vol.5
, pp. 857-866
-
-
Gottlieb, E.1
Tomlinson, I.P.M.2
-
79
-
-
34250665634
-
Zinc as an anti-tumor agent in prostate cancer and in other cancers
-
Franklin, R. B., and Costello, L. C. (2007) Zinc as an anti-tumor agent in prostate cancer and in other cancers. Arch. Biochem. Biophys. 463, 211-217.
-
(2007)
Arch. Biochem. Biophys.
, vol.463
, pp. 211-217
-
-
Franklin, R.B.1
Costello, L.C.2
-
80
-
-
34547662880
-
Effect of metabolic inhibitors on ATP and citrate content in PC3 prostate cancer cells
-
Matheson, B. K., Adams, J. L., Zou, J., Patel, R., and Franklin, R. B. (2007) Effect of metabolic inhibitors on ATP and citrate content in PC3 prostate cancer cells. Prostate 67, 1211-1218.
-
(2007)
Prostate
, vol.67
, pp. 1211-1218
-
-
Matheson, B.K.1
Adams, J.L.2
Zou, J.3
Patel, R.4
Franklin, R.B.5
-
81
-
-
50149097983
-
Hypoxia HIF1 and glucose metabolism in the solid tumour
-
Denko, N. C. (2008) Hypoxia, HIF1 and glucose metabolism in the solid tumour. Nat. Rev. Cancer 8, 705-713.
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 705-713
-
-
Denko, N.C.1
-
82
-
-
0018386209
-
Evidence that glutamine, not sugar, is the major energy source for cultured HeLa cells
-
Reitzer, L. J., Wice, B. M., and Kennell, D. (1979) Evidence that glutamine, not sugar, is the major energy source for cultured HeLa cells. J. Biol. Chem. 254, 2669-2676.
-
(1979)
J. Biol. Chem.
, vol.254
, pp. 2669-2676
-
-
Reitzer, L.J.1
Wice, B.M.2
Kennell, D.3
-
83
-
-
33746901971
-
Control of cellular proliferation by modulation of oxidative phosphorylation in human and rodent fast-growing tumor cells
-
Rodríguez-Enríquez, S., Vital-González, P. A., Flores-Rodríguez, F. L., Marín-Hernández, A., Ruiz-Azuara, L., and Moreno-Sánchez, R. (2006) Control of cellular proliferation by modulation of oxidative phosphorylation in human and rodent fast-growing tumor cells. Toxicol. Appl. Pharmacol. 215, 208-217.
-
(2006)
Toxicol. Appl. Pharmacol.
, vol.215
, pp. 208-217
-
-
Rodríguez-Enríquez, S.1
Vital-González, P.A.2
Flores-Rodríguez, F.L.3
Marín-Hernández, A.4
Ruiz-Azuara, L.5
Moreno-Sánchez, R.6
-
84
-
-
0037093411
-
Contribution by different fuels and metabolic pathways to the total ATP turnover of proliferating MCF-7 breast cancer cells
-
Guppy, M., Leedman, P., Zu, X., and Russell, V. (2002) Contribution by different fuels and metabolic pathways to the total ATP turnover of proliferating MCF-7 breast cancer cells. Biochem. J. 364, 309-315.
-
(2002)
Biochem. J.
, vol.364
, pp. 309-315
-
-
Guppy, M.1
Leedman, P.2
Zu, X.3
Russell, V.4
-
85
-
-
33745512245
-
Mitochondrial aconitase and citrate metabolism in malignant and nonmalignant human prostate tissues
-
Singh, K. K., Desouki, M. M., Franklin, R. B., and Costello, L. C. (2006) Mitochondrial aconitase and citrate metabolism in malignant and nonmalignant human prostate tissues. Mol. Cancer 5, 14.
-
(2006)
Mol. Cancer
, vol.5
, pp. 14
-
-
Singh, K.K.1
Desouki, M.M.2
Franklin, R.B.3
Costello, L.C.4
-
86
-
-
34249009033
-
Modulation of succinate transport in Hep G2 cell line by PKC. Biochim
-
Srisawang, P., Chatsudthipong, A., and Chatsudthipong, V. (2007) Modulation of succinate transport in Hep G2 cell line by PKC. Biochim. Biophys. Acta 1768, 1378-1388.
-
(2007)
Biophys. Acta
, vol.1768
, pp. 1378-1388
-
-
Srisawang, P.1
Chatsudthipong, A.2
Chatsudthipong, V.3
-
87
-
-
40949108885
-
Identification of transport pathways for citric acid cycle intermediates in the human colon carcinoma cell line Caco-2
-
Weerachayaphorn, J., and Pajor, A. M. (2008) Identification of transport pathways for citric acid cycle intermediates in the human colon carcinoma cell line, Caco-2. Biochim. Biophys. Acta 1778, 1051-1059.
-
(2008)
Biochim. Biophys. Acta
, vol.1778
, pp. 1051-1059
-
-
Weerachayaphorn, J.1
Pajor, A.M.2
-
88
-
-
37449024702
-
The biology of cancer: Metabolic reprogramming fuels cell growth and proliferation
-
DeBerardinis, R. J., Lum, J. J., Hatzivassiliou, G., and Thompson, C. B. (2008).The biology of cancer: metabolic reprogramming fuels cell growth and proliferation. Cell. Metabolism 7, 11-20.
-
(2008)
Cell. Metabolism
, vol.7
, pp. 11-20
-
-
Deberardinis, R.J.1
Lum, J.J.2
Hatzivassiliou, G.3
Thompson, C.B.4
-
89
-
-
0034283023
-
Vascular endothelial growth factor, interleukin 8, platelet-derived endothelial cell growth factor, and basic fibroblast growth factor promote angiogenesis and metastasis in human melanoma xenografts
-
Rofstad, E. R., and Halsor, E. F. (2000) Vascular endothelial growth factor, interleukin 8, platelet-derived endothelial cell growth factor, and basic fibroblast growth factor promote angiogenesis and metastasis in human melanoma xenografts. Cancer Res. 60, 4932-4938.
-
(2000)
Cancer Res.
, vol.60
, pp. 4932-4938
-
-
Rofstad, E.R.1
Halsor, E.F.2
-
90
-
-
34547121206
-
Hypoxia in cancer: Significance and impact on clinical outcome
-
Vaupel, P., and Mayer, A. (2007) Hypoxia in cancer: significance and impact on clinical outcome. Cancer Metastasis Rev. 26, 225-239.
-
(2007)
Cancer Metastasis Rev.
, vol.26
, pp. 225-239
-
-
Vaupel, P.1
Mayer, A.2
-
91
-
-
0028170474
-
2- and pH-gradients in multicellular spheroids and their relationship to cellular metabolism and radiation sensitivity of malignant human tumor cells
-
O2- and pH-gradients in multicellular spheroids and their relationship to cellular metabolism and radiation sensitivity of malignant human tumor cells. Biochim. Biophys. Acta 1227, 105-112.
-
(1994)
Biochim. Biophys. Acta
, vol.1227
, pp. 105-112
-
-
Gorlach, A.1
Acker, H.2
-
92
-
-
0032054171
-
Regional tumor oximetry: 19F NMR spectroscopy of hexafluorobenzene
-
Hunjan, S., Mason, R. P., Constantinescu, A., Peschke, P., Hahn, E. W., and Antich, P. P. (1998) Regional tumor oximetry: 19F NMR spectroscopy of hexafluorobenzene. Int. J. Radiat. Oncol. Biol. Phys. 41, 161-171.
-
(1998)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.41
, pp. 161-171
-
-
Hunjan, S.1
Mason, R.P.2
Constantinescu, A.3
Peschke, P.4
Hahn, E.W.5
Antich, P.P.6
-
93
-
-
28444437729
-
Absolute oxygen tension (pO(2)) in murine fatty and muscle tissue as determined by EPR
-
Matsumoto, A., Sowers, A. L., Koscielniak, J. W., Trigg, N. J., Kuppusamy, P., Mitchell, J. B., Subramanian, S., Krishna, M. C., and Matsumoto, K. (2005) Absolute oxygen tension (pO(2)) in murine fatty and muscle tissue as determined by EPR. Magn. Reson. Med. 57, 1530-1535.
-
(2005)
Magn. Reson. Med.
, vol.57
, pp. 1530-1535
-
-
Matsumoto, A.1
Sowers, A.L.2
Koscielniak, J.W.3
Trigg, N.J.4
Kuppusamy, P.5
Mitchell, J.B.6
Subramanian, S.7
Krishna, M.C.8
Matsumoto, K.9
-
94
-
-
35448972596
-
Patterns and levels of hypoxia in head and neck squamous cell carcinomas and their relationship to pattern outcome
-
Evans, S. M., Du, K. L., Chalian, A. A., Mick, R., Zhang, P. J., Hahn, S. M., Quon, H., Lustig, R., Weinstein, G. S., and Koch, C. J. (2007) Patterns and levels of hypoxia in head and neck squamous cell carcinomas and their relationship to pattern outcome. Int. J. Radiat. Oncol. Biol. Phys. 69, 1024-1031.
-
(2007)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.69
, pp. 1024-1031
-
-
Evans, S.M.1
Du, K.L.2
Chalian, A.A.3
Mick, R.4
Zhang, P.J.5
Hahn, S.M.6
Quon, H.7
Lustig, R.8
Weinstein, G.S.9
Koch, C.J.10
-
96
-
-
0041633808
-
Effect of longitudinal oxygen gradients on effectiveness of manipulation of tumor oxygenation
-
Erickson, K., Braun, R. D., Yu, D., Lanzen, J., Wilson, D., Brizel, D. M., Secomb, T. W., Biaglow, J. E., and Dewhirst, M. W. (2003) Effect of longitudinal oxygen gradients on effectiveness of manipulation of tumor oxygenation. Cancer Res. 63, 4705-4712.
-
(2003)
Cancer Res.
, vol.63
, pp. 4705-4712
-
-
Erickson, K.1
Braun, R.D.2
Yu, D.3
Lanzen, J.4
Wilson, D.5
Brizel, D.M.6
Secomb, T.W.7
Biaglow, J.E.8
Dewhirst, M.W.9
-
97
-
-
0014389382
-
Intercapillary distance, oxygen tension and local recurrence in cervix cancer. Scand
-
Kolstad, P. (1968) Intercapillary distance, oxygen tension and local recurrence in cervix cancer. Scand. J. Clin. Lab. Invest. Suppl. 196, 145-157.
-
(1968)
J. Clin. Lab. Invest. Suppl.
, vol.196
, pp. 145-157
-
-
Kolstad, P.1
-
98
-
-
0024311944
-
Blood flow, metabolism, cellular microenvironment, and growth rate of human tumor xenografts
-
Kallinowski, F., Schlenger, K. H., Runkel, S., Kloes, M., Stohrer, M., Okunieff, P., and Vaupel, P. (1989) Blood flow, metabolism, cellular microenvironment, and growth rate of human tumor xenografts. Cancer Res. 49, 3759-3764.
-
(1989)
Cancer Res.
, vol.49
, pp. 3759-3764
-
-
Kallinowski, F.1
Schlenger, K.H.2
Runkel, S.3
Kloes, M.4
Stohrer, M.5
Okunieff, P.6
Vaupel, P.7
-
99
-
-
0029658470
-
Hexafluorobenzene: A sensitive 19F NMR indicator of tumor oxygenation
-
Mason, R. P., Rodbumrung, W., and Antich, P. P. (1996) Hexafluorobenzene: a sensitive 19F NMR indicator of tumor oxygenation. NMR Biomed. 9, 125-134.
-
(1996)
NMR Biomed.
, vol.9
, pp. 125-134
-
-
Mason, R.P.1
Rodbumrung, W.2
Antich, P.P.3
-
100
-
-
0034760535
-
Tumor oxygen dynamics with respect to growth and respiratory challenge: Investigation of the Dunning prostate R3327-HI tumor
-
Zhao, D., Constantinescu, A., Hahn, E. W., and Mason, R. P. (2001) Tumor oxygen dynamics with respect to growth and respiratory challenge: investigation of the Dunning prostate R3327-HI tumor. Radiat. Res. 156, 510-520.
-
(2001)
Radiat. Res.
, vol.156
, pp. 510-520
-
-
Zhao, D.1
Constantinescu, A.2
Hahn, E.W.3
Mason, R.P.4
-
101
-
-
34147187169
-
A highly sensitive biocompatible spin probe for imaging of oxygen concentration in tissues
-
Bratasz, A., Kulkarni, A. C., and Kuppusamy, P. (2007) A highly sensitive biocompatible spin probe for imaging of oxygen concentration in tissues. Biophys. J. 92, 2918-2925.
-
(2007)
Biophys. J.
, vol.92
, pp. 2918-2925
-
-
Bratasz, A.1
Kulkarni, A.C.2
Kuppusamy, P.3
-
102
-
-
0000959996
-
The respiration of ascites tumor cells at low oxygen concentrations
-
Froese, G. (1962) The respiration of ascites tumor cells at low oxygen concentrations. Biochim. Biophys. Acta 57, 509-519.
-
(1962)
Biochim. Biophys. Acta
, vol.57
, pp. 509-519
-
-
Froese, G.1
-
103
-
-
0032052209
-
Mitochondrial oxygen affinity, respiratory flux control and excess capacity of cytochrome c oxidase
-
Gnaiger, E., Lassnig, B., Kuznetsov, A., Rieger, G., and Margreiter, R. (1998) Mitochondrial oxygen affinity, respiratory flux control and excess capacity of cytochrome c oxidase. J. Exp. Biol. 201, 1129-1139.
-
(1998)
J. Exp. Biol.
, vol.201
, pp. 1129-1139
-
-
Gnaiger, E.1
Lassnig, B.2
Kuznetsov, A.3
Rieger, G.4
Margreiter, R.5
-
104
-
-
6044224891
-
Decreased affinity for oxygen of cytochrome-c oxidase in Leigh syndrome caused by SURF1 mutations
-
Pecina, P., Gnaiger, E., Zeman, J., Pronicka, E., and Houštěk, T. (2004) Decreased affinity for oxygen of cytochrome-c oxidase in Leigh syndrome caused by SURF1 mutations. Am. J. Physiol. Cell. Physiol. 287, C1384-C1388
-
(2004)
Am. J. Physiol. Cell. Physiol.
, vol.287
-
-
Pecina, P.1
Gnaiger, E.2
Zeman, J.3
Pronicka, E.4
Houštěk, T.5
-
105
-
-
31444433077
-
Nitric oxide inhibition of respiration involves both competitive (heme) and noncompetitive (copper) binding to cytochrome c oxidase
-
Mason, M. G., Nicholls, P., Wilson, M. T., and Cooper, C. E. (2006) Nitric oxide inhibition of respiration involves both competitive (heme) and noncompetitive (copper) binding to cytochrome c oxidase. Proc. Natl. Acad. Sci. USA. 103, 708-713.
-
(2006)
Proc. Natl. Acad. Sci. USA.
, vol.103
, pp. 708-713
-
-
Mason, M.G.1
Nicholls, P.2
Wilson, M.T.3
Cooper, C.E.4
-
106
-
-
0030045543
-
Isoenzyme-specific regulation of genes involved in energy metabolism by hypoxia: Similarities with the regulation of erythropoietin
-
Ebert, B. L., Gleade, J. M., O'Rourke, J. F., Bartlett, S. M., Poulton, J., and Ratcliffe, P. J. (1996) Isoenzyme-specific regulation of genes involved in energy metabolism by hypoxia: similarities with the regulation of erythropoietin. Biochem. J. 313, 809-814.
-
(1996)
Biochem. J.
, vol.313
, pp. 809-814
-
-
Ebert, B.L.1
Gleade, J.M.2
O'rourke, J.F.3
Bartlett, S.M.4
Poulton, J.5
Ratcliffe, P.J.6
-
107
-
-
0035107731
-
Hypoxia regulates glutamate metabolism and membrane transport in rat PC12 cells
-
Kobayashi, S., and Milhorn, D. E. (2001) Hypoxia regulates glutamate metabolism and membrane transport in rat PC12 cells. J. Neurochem. 76, 1935-1948.
-
(2001)
J. Neurochem.
, vol.76
, pp. 1935-1948
-
-
Kobayashi, S.1
Milhorn, D.E.2
-
108
-
-
0022870258
-
Quantification of ATP-producing and consuming processes of Ehrlich ascites tumour cells
-
Muller, M., Siems, W., Buttgereit, F., Dumdey, R., and Rapoport, S. M. (1986) Quantification of ATP-producing and consuming processes of Ehrlich ascites tumour cells. Eur. J. Biochem. 161, 701-705.
-
(1986)
Eur. J. Biochem.
, vol.161
, pp. 701-705
-
-
Muller, M.1
Siems, W.2
Buttgereit, F.3
Dumdey, R.4
Rapoport, S.M.5
-
109
-
-
0347694776
-
Cancer metabolism: Facts, fantasy, and fiction
-
Zu, X. L., and Guppy, M. (2004) Cancer metabolism: facts, fantasy, and fiction. Biochem. Biophys. Res. Commun. 313, 459-465.
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.313
, pp. 459-465
-
-
Zu, X.L.1
Guppy, M.2
-
110
-
-
0021750757
-
Contributions of glycolysis and oxidative phosphorylation to adenosine 50-triphosphate production in AS-30D hepatoma cells
-
Nakashima, R. A., Paggi, M. G., and Pedersen, P. L. (1984) Contributions of glycolysis and oxidative phosphorylation to adenosine 50-triphosphate production in AS-30D hepatoma cells. Cancer Res. 44, 5702-5706.
-
(1984)
Cancer Res.
, vol.44
, pp. 5702-5706
-
-
Nakashima, R.A.1
Paggi, M.G.2
Pedersen, P.L.3
-
112
-
-
44949104134
-
-
Metabolic control analysis: A tool for designing strategies to manipulate metabolic pathways, Art. No. 597913
-
Moreno-Sánchez, R., Saavedra, E., Rodríguez- Enríquez, S., and Olín- Sandoval, V. (2008) Metabolic control analysis: A tool for designing strategies to manipulate metabolic pathways,J. Biomed. Biotechnol. 2008, Art. No.597913.
-
(2008)
J. Biomed. Biotechnol. 2008
-
-
Moreno-Sánchez, R.1
Saavedra, E.2
Rodríguez-Enríquez, S.3
Olín- Sandoval, V.4
-
113
-
-
0342514653
-
Substrate oxidation and ATP supply in AS-30D hepatoma cells
-
Rodríguez-Enríquez, S., Torres-Márquez, M. E., and Moreno-Sánchez, R. (2000) Substrate oxidation and ATP supply in AS-30D hepatoma cells. Arch. Biochem. Biophys. 375, 21-30.
-
(2000)
Arch. Biochem. Biophys.
, vol.375
, pp. 21-30
-
-
Rodríguez-Enríquez, S.1
Torres-Márquez, M.E.2
Moreno-Sánchez, R.3
-
114
-
-
26944452745
-
Glucose metabolism heterogeneity in human and mouse malignant glioma cell lines
-
Griguer, C. E., Oliva, C. R., and Gillespie, G. Y. (2005) Glucose metabolism heterogeneity in human and mouse malignant glioma cell lines. J. Neurooncol. 74, 123-133.
-
(2005)
J. Neurooncol.
, vol.74
, pp. 123-133
-
-
Griguer, C.E.1
Oliva, C.R.2
Gillespie, G.Y.3
-
115
-
-
34548490075
-
A ROS generator, antimycin A, inhibits the growth of HeLa cells via apoptosis
-
Park, Y. W., Kim, S. H., and Kim, S. Z. (2007) A ROS generator, antimycin A, inhibits the growth of HeLa cells via apoptosis. J. Cell Biochem. 102, 98-109.
-
(2007)
J. Cell Biochem.
, vol.102
, pp. 98-109
-
-
Park, Y.W.1
Kim, S.H.2
Kim, S.Z.3
-
116
-
-
0024308302
-
Reduction of intracellular pH as a possible mechanism for killing cells in acidic regions of solid tumors: Effects of carbonylcyanide-3- chlorophenylhydrazone
-
Newell, K. J., and Tannock, I. F. (1989) Reduction of intracellular pH as a possible mechanism for killing cells in acidic regions of solid tumors: effects of carbonylcyanide-3-chlorophenylhydrazone. Cancer Res. 49, 4477-4482.
-
(1989)
Cancer Res.
, vol.49
, pp. 4477-4482
-
-
Newell, K.J.1
Tannock, I.F.2
-
117
-
-
11444255268
-
On respiratory impairment in cancer cells
-
Weinhouse, S. (1956) On respiratory impairment in cancer cells. Science 124, 267-269.
-
(1956)
Science
, vol.124
, pp. 267-269
-
-
Weinhouse, S.1
-
118
-
-
44449149325
-
Energy metabolism transition in multi-cellular human tumor spheroids
-
Rodríguez-Enríquez, S., Gallardo-Pérez, J. C., Avilés-Salas, A., Marín- Hernández, A., Carreño-Fuentes, L., Maldonado-Lagunas, V., and Moreno- Sánchez, R. (2008) Energy metabolism transition in multi-cellular human tumor spheroids. J. Cell Physiol. 216, 189-197.
-
(2008)
J. Cell Physiol.
, vol.216
, pp. 189-197
-
-
Rodríguez-Enríquez, S.1
Gallardo-Pérez, J.C.2
Avilés-Salas, A.3
Marín- Hernández, A.4
Carreño-Fuentes, L.5
Maldonado-Lagunas, V.6
Moreno- Sánchez, R.7
-
119
-
-
0027264066
-
Enhancement of heme oxygenase expression and activity in A431 squamous carcinoma multicellular tumor spheroids
-
Murphy, B. J., Laderoute, V. R., Vreman, H. J., Grant, T. D., Gill, N. S., Stevenson, D. K., and Sutherland, R. M. (1993) Enhancement of heme oxygenase expression and activity in A431 squamous carcinoma multicellular tumor spheroids. Cancer Res. 53, 2700-2703.
-
(1993)
Cancer Res.
, vol.53
, pp. 2700-2703
-
-
Murphy, B.J.1
Laderoute, V.R.2
Vreman, H.J.3
Grant, T.D.4
Gill, N.S.5
Stevenson, D.K.6
Sutherland, R.M.7
-
120
-
-
0026163635
-
ATP-producing and consuming processes of Ehrlich mouse ascites tumor cells in proliferating and resting phases
-
Schmidt, H., Siems,W. G., Muller, M., Dumdey, R., and Rapoport, S. (1991) ATP-producing and consuming processes of Ehrlich mouse ascites tumor cells in proliferating and resting phases. Exp. Cell. Res. 194, 122-127.
-
(1991)
Exp. Cell. Res.
, vol.194
, pp. 122-127
-
-
Schmidt, H.1
Siems, W.G.2
Muller, M.3
Dumdey, R.4
Rapoport, S.5
-
121
-
-
0026542467
-
Balancing of energy-consuming processes of K 562 cells
-
Siems, W. G., Schmidt, H., Gruner, S., and Jakstadt, M. (2004) Balancing of energy-consuming processes of K 562 cells. Cell. Biochem. Funct. 10, 61-66.
-
(2004)
Cell. Biochem. Funct.
, vol.10
, pp. 61-66
-
-
Siems, W.G.1
Schmidt, H.2
Gruner, S.3
Jakstadt, M.4
-
122
-
-
4444245853
-
Mitochondrial proteome: Cancer-altered metabolism associated with cytochrome c oxidase subunit level variation
-
Krieg, R. C., Knuechel, R., Schiffmann, E., Liotta, L. A., Petricoin, E. F., III, and Herrmann, P. C. (2004) Mitochondrial proteome: cancer-altered metabolism associated with cytochrome c oxidase subunit level variation. Proteomics 4, 2789-2795.
-
(2004)
Proteomics
, vol.4
, pp. 2789-2795
-
-
Krieg, R.C.1
Knuechel, R.2
Schiffmann, E.3
Liotta, L.A.4
Petricoin Iii, E.F.5
Herrmann, P.C.6
-
123
-
-
0034652620
-
High lactate levels predict likelihood of metastases, tumor recurrence, and restricted patient survival in human cervical cancers
-
Walenta, S., Wetterling, M., Lehrke, M., Schwickert, G., Sundfor, K., Rofstad, E. K., and Mueller-Klieser, W. (2000) High lactate levels predict likelihood of metastases, tumor recurrence, and restricted patient survival in human cervical cancers. Cancer Res. 60, 916-921.
-
(2000)
Cancer Res.
, vol.60
, pp. 916-921
-
-
Walenta, S.1
Wetterling, M.2
Lehrke, M.3
Schwickert, G.4
Sundfor, K.5
Rofstad, E.K.6
Mueller-Klieser, W.7
-
124
-
-
12944262229
-
Molecular and cellular regulation of glucose transporter (GLUT) proteins in cancer
-
Macheda, M. L., Rogers, S., and Best, J. D. (2005) Molecular and cellular regulation of glucose transporter (GLUT) proteins in cancer. J. Cell. Physiol. 202, 654-662.
-
(2005)
J. Cell. Physiol.
, vol.202
, pp. 654-662
-
-
MacHeda, M.L.1
Rogers, S.2
Best, J.D.3
-
125
-
-
43849113286
-
Aberrant expression of the glycolytic enzymes aldolase B and type II hexokinase in hepatocellular carcinoma are predictive markers for advanced stage, early recurrence and poor prognosis
-
Peng, S. Y., Lai, P. L., Pan, H. W., Hsiao, L. P., and Hsu, H. C. (2008) Aberrant expression of the glycolytic enzymes aldolase B and type II hexokinase in hepatocellular carcinoma are predictive markers for advanced stage, early recurrence and poor prognosis. Oncol. Rep. 19, 1045-1053.
-
(2008)
Oncol. Rep.
, vol.19
, pp. 1045-1053
-
-
Peng, S.Y.1
Lai, P.L.2
Pan, H.W.3
Hsiao, L.P.4
Hsu, H.C.5
-
126
-
-
0019302275
-
The energy charge in wild-type and respiration-deficient Chinese hamster cell mutants
-
Soderberg, K., Nissinen, E., Bakay, B., and Scheffler, I. E. (1980) The energy charge in wild-type and respiration-deficient Chinese hamster cell mutants. J. Cell Physiol. 103, 169-172.
-
(1980)
J. Cell Physiol.
, vol.103
, pp. 169-172
-
-
Soderberg, K.1
Nissinen, E.2
Bakay, B.3
Scheffler, I.E.4
-
127
-
-
33746877057
-
Contribution of somatic mutations in the mitochondrial genome to the development of cancer and tolerance against anticancer drugs
-
Ohta, S. (2006) Contribution of somatic mutations in the mitochondrial genome to the development of cancer and tolerance against anticancer drugs. Oncogene 25, 4768-4776.
-
(2006)
Oncogene
, vol.25
, pp. 4768-4776
-
-
Ohta, S.1
-
128
-
-
0030446237
-
Extended multidrug resistance in haemopoietic cells
-
Marks, D. C., Su, G. M., Davey, R. A., and Davey, M. W. (1996) Extended multidrug resistance in haemopoietic cells. Br. J. Haematol. 95, 587-595.
-
(1996)
Br. J. Haematol.
, vol.95
, pp. 587-595
-
-
Marks, D.C.1
Su, G.M.2
Davey, R.A.3
Davey, M.W.4
-
129
-
-
0036793525
-
Characterization of a novel metabolic strategy used by drug-resistant tumor cells
-
Harper, M. E., Antoniou, A., Villalobos-Manuey, E., Russo, A., Trauger, R., Vendemelio, M., George, A., Bartholomew, R., Carlo, D., Shaikh, A., Kupperman, J., Newell, E. W., Bespalov, I. A., Wallace, S. S., Liu, Y., J.Rogers, R., Gibbs, G. L., Leahy, J. L., Camley, R. E., Melamede, R., and Newell, M. K. (2002) Characterization of a novel metabolic strategy used by drug-resistant tumor cells. FASEB J. 16, 1550-1557.
-
(2002)
FASEB J.
, vol.16
, pp. 1550-1557
-
-
Harper, M.E.1
Antoniou, A.2
Villalobos-Manuey, E.3
Russo, A.4
Trauger, R.5
Vendemelio, M.6
George, A.7
Bartholomew, R.8
Carlo, D.9
Shaikh, A.10
Kupperman, J.11
Newell, E.W.12
Bespalov, I.A.13
Wallace, S.S.14
Liu, Y.15
Rogers, J.R.16
Gibbs, G.L.17
Leahy, J.L.18
Camley, R.E.19
Melamede, R.20
Newell, M.K.21
more..
-
130
-
-
0030064081
-
MKT-077, a novel rhodacyanine dye in clinical trials, exhibits anticarcinoma activity in preclinical studies based on selective mitochondrial accumulation
-
Koya, K., Li, Y., Wang, H., Ukai, T., Tatsuta, N., Kawakami, M., Shishido, T., and Chen, L. B. (1996) MKT-077, a novel rhodacyanine dye in clinical trials, exhibits anticarcinoma activity in preclinical studies based on selective mitochondrial accumulation. Cancer Res. 56, 538-543.
-
(1996)
Cancer Res.
, vol.56
, pp. 538-543
-
-
Koya, K.1
Li, Y.2
Wang, H.3
Ukai, T.4
Tatsuta, N.5
Kawakami, M.6
Shishido, T.7
Chen, L.B.8
-
131
-
-
0028318531
-
Excess membrane cholesterol is not responsible for metabolic and bioenergetic changes in AS-30D hepatoma mitochondria
-
Dietzen, D. J., and Davis, E. J. (1994) Excess membrane cholesterol is not responsible for metabolic and bioenergetic changes in AS-30D hepatoma mitochondria. Arch. Biochem. Biophys. 309, 341-347.
-
(1994)
Arch. Biochem. Biophys.
, vol.309
, pp. 341-347
-
-
Dietzen, D.J.1
Davis, E.J.2
-
132
-
-
0034672530
-
Rho (0) tumor cells: A model for studying whether mitochondria are targets for rhodamine 123, doxorubicin and other drugs
-
Hu, Y., Moraes, C. T., Savaraj, N., Priebe, W., and Lampidis, T. J. (2000) Rho (0) tumor cells: a model for studying whether mitochondria are targets for rhodamine 123, doxorubicin and other drugs. Biochem. Pharmacol. 60, 1897-1905.
-
(2000)
Biochem. Pharmacol.
, Issue.60
, pp. 1897-1905
-
-
Hu, Y.1
Moraes, C.T.2
Savaraj, N.3
Priebe, W.4
Lampidis, T.J.5
-
133
-
-
2442631713
-
Vitamin analogues: A new class of inducers of apoptosis with selective anti-cancer effect
-
Neuzil, J., Tomasetti, M., Mellick, A. S., Alleva, R., Salvatore, B. A., Birringer, B., and Fariss, M. W. (2004) Vitamin analogues: a new class of inducers of apoptosis with selective anti-cancer effect. Curr. Cancer Drug Targets 4, 267-284.
-
(2004)
Curr. Cancer Drug Targets
, vol.4
, pp. 267-284
-
-
Neuzil, J.1
Tomasetti, M.2
Mellick, A.S.3
Alleva, R.4
Salvatore, B.A.5
Birringer, B.6
Fariss, M.W.7
-
134
-
-
0035131831
-
The rate-limiting step for tumor [18F] fluoro-2-deoxy-D-glucose (FDG) incorporation
-
Smith, T. A. (2001) The rate-limiting step for tumor [18F] fluoro-2-deoxy-D-glucose (FDG) incorporation. Nucl. Med. Biol. 28, 1-4.
-
(2001)
Nucl. Med. Biol.
, vol.28
, pp. 1-4
-
-
Smith, T.A.1
-
135
-
-
0036176751
-
Positron emission tomography scanning: Current and future applications
-
Czernin, J., and Phelps, M. E. (2002) Positron emission tomography scanning: current and future applications. Annu. Rev. Med. 53, 89-112.
-
(2002)
Annu. Rev. Med.
, vol.53
, pp. 89-112
-
-
Czernin, J.1
Phelps, M.E.2
-
136
-
-
2442631713
-
Vitamin e analogues: A new class of inducers of apoptosis with selective anti-cancer effects
-
Berberat, P., Friess, H., Kashiwagi, M., Beger, H. G., and B̈chler, M. W. (2004) Vitamin E analogues: a new class of inducers of apoptosis with selective anti-cancer effects. Curr. Cancer Drug Targets 4, 355-372.
-
(2004)
Curr. Cancer Drug Targets
, vol.4
, pp. 355-372
-
-
Berberat, P.1
Friess, H.2
Kashiwagi, M.3
Beger, H.G.4
B̈chler, M.W.5
-
137
-
-
33745882957
-
False positive and false negative FDG-PET scans in various thoracic diseases
-
Chang, J. M., Lee, H. L., Goo, J. M., Lee, J. J., Chung, J. K., and Im, J. G. (2006) False positive and false negative FDG-PET scans in various thoracic diseases. Korean J. Radiol. 7, 57-69.
-
(2006)
Korean J. Radiol.
, vol.7
, pp. 57-69
-
-
Chang, J.M.1
Lee, H.L.2
Goo, J.M.3
Lee, J.J.4
Chung, J.K.5
Im, J.G.6
-
138
-
-
0027976893
-
Microautoradiographic study for the differentiation of intratumoral macrophages, granulation tissues and cancer cells by the dynamics of fluorine-18-fluorodeoxyglucose uptake
-
Kubota, R., Kubota, K., Yamada, S., Ido, T., and Tamashi, N. (1994) Microautoradiographic study for the differentiation of intratumoral macrophages, granulation tissues and cancer cells by the dynamics of fluorine-18- fluorodeoxyglucose uptake. J. Nucl. Med. 35, 104-112. (Pubitemid 24018451)
-
(1994)
Journal of Nuclear Medicine
, vol.35
, Issue.1
, pp. 104-112
-
-
Kubota, R.1
Kubota, K.2
Yamada, S.3
Tada, M.4
Ido, T.5
Tamahashi, N.6
-
139
-
-
0031863737
-
Fluorine-18-FDG PET imaging is negative in bronchioloalveolar lung carcinoma
-
Higashi, K., Ueda, Y., Seki, H., Yuasa, K., Oguchi, M., Noguchi, T., Taniguchi, M., Tonami, H., Okimura, T., and Yamamoto, I. (1998) Fluorine-18-FDG PET imaging is negative in bronchioloalveolar lung carcinoma. J. Nucl. Med. 39, 1016-1020.
-
(1998)
J. Nucl. Med.
, vol.39
, pp. 1016-1020
-
-
Higashi, K.1
Ueda, Y.2
Seki, H.3
Yuasa, K.4
Oguchi, M.5
Noguchi, T.6
Taniguchi, M.7
Tonami, H.8
Okimura, T.9
Yamamoto, I.10
-
140
-
-
60549097432
-
High incidence of false positive PET scans in patients with aggressive non-Hodgkins lymphoma treated with rituximab-containing regimens
-
Han, H. S., Escalón, M. P., Hsiao, B., Sarefini, A., and Lossos, I. S. (2009) High incidence of false positive PET scans in patients with aggressive non-Hodgkins lymphoma treated with rituximab-containing regimens. Ann. Oncol. 2, 309-318.
-
(2009)
Ann. Oncol.
, vol.2
, pp. 309-318
-
-
Han, H.S.1
Escalón, M.P.2
Hsiao, B.3
Sarefini, A.4
Lossos, I.S.5
-
141
-
-
33748120494
-
PET and PET/CT using 18FDG in the diagnosis and management of cancer patients
-
Endo, K., Oriuchi, N., Higuchi, T., Lida, Y., Hanaoka, H., Miyakubo, M., Ishikita, T., and Koyama, K. (2006) PET and PET/CT using 18FDG in the diagnosis and management of cancer patients. Int. J. Clin. Oncol. 11, 286-296.
-
(2006)
Int. J. Clin. Oncol.
, vol.11
, pp. 286-296
-
-
Endo, K.1
Oriuchi, N.2
Higuchi, T.3
Lida, Y.4
Hanaoka, H.5
Miyakubo, M.6
Ishikita, T.7
Koyama, K.8
-
142
-
-
0028832293
-
Vivo assessment of glucose metabolism in hepatocellular carcinoma with FDG/PET
-
Torizuka, T., Tamaki, N., and Inokuma, T. (1995) In vivo assessment of glucose metabolism in hepatocellular carcinoma with FDG/PET. J. Nucl. Med. 36, 1811-1817.
-
(1995)
J. Nucl. Med.
, vol.36
, pp. 1811-1817
-
-
Torizuka, T.1
Tamaki, N.2
Inokuma, T.3
-
143
-
-
4143094738
-
Treatment of advanced differentiated thyroid carcinoma with high activity radioiodine therapy
-
Haq, M. S., McCready, R. M., and Harmer, C. L. (2004) Treatment of advanced differentiated thyroid carcinoma with high activity radioiodine therapy. Nucl. Med. Commun. 25, 799-805.
-
(2004)
Nucl. Med. Commun.
, vol.25
, pp. 799-805
-
-
Haq, M.S.1
McCready, R.M.2
Harmer, C.L.3
-
144
-
-
33845352355
-
2-polarography in metastatic head and neck cancer
-
Zimny, M., Gagel, B., Dimartino, E., Hamacker, K., Coenen, H. H., Westhofen, M., Eble, M., Buell, U., and Reinartz, P. (2006) FDG- a marker of tumour hypoxia? A comparison with [18F] fluoromisonidazole and pO2-polarography in metastatic head and neck cancer. Eur. J. Nucl. Med. Mol. Imaging 33, 1426-1431.
-
(2006)
Eur. J. Nucl. Med. Mol. Imaging
, vol.33
, pp. 1426-1431
-
-
Zimny, M.1
Gagel, B.2
Dimartino, E.3
Hamacker, K.4
Coenen, H.H.5
Westhofen, M.6
Eble, M.7
Buell, U.8
Reinartz, P.9
-
145
-
-
54949157918
-
Tumor hypoxia detected by positron emission tomography with 60Cu-ATSM as a predictor of response and survival in patients undergoing neoadjuvant chemoradiotherapy for rectal carcinoma: A pilot study
-
Dietz, D. W., Dehdashti, F., Grigsby, P. W., Myalyapa, R. S., Myerson, R. J., Picus, J., Ritter, J., Lewis, J. S., Welch, M. J., and Siegel, B. A. (2008) Tumor hypoxia detected by positron emission tomography with 60Cu-ATSM as a predictor of response and survival in patients undergoing neoadjuvant chemoradiotherapy for rectal carcinoma: a pilot study. Dis. Colon Rectum 51, 1641-1648.
-
(2008)
Dis. Colon Rectum
, vol.51
, pp. 1641-1648
-
-
Dietz, D.W.1
Dehdashti, F.2
Grigsby, P.W.3
Myalyapa, R.S.4
Myerson, R.J.5
Picus, J.6
Ritter, J.7
Lewis, J.S.8
Welch, M.J.9
Siegel, B.A.10
-
146
-
-
0028902219
-
Differential mechanism of retention of Cu-pyruvaldehyde-bis(N4- methylthiosemicarbazone) (Cu-PTSM) by brain and tumor: A novel radiopharmaceutical for positron emission tomography imaging
-
Fujibayashi, Y., Taniuchi, H., Wada, K., Yonekura, Y., Konishi, J., Yokoyama, A. (1995) Differential mechanism of retention of Cu-pyruvaldehyde- bis(N4-methylthiosemicarbazone) (Cu-PTSM) by brain and tumor: a novel radiopharmaceutical for positron emission tomography imaging. Ann. Nucl. Med. 9, 1-5.
-
(1995)
Ann. Nucl. Med.
, vol.9
, pp. 1-5
-
-
Fujibayashi, Y.1
Taniuchi, H.2
Wada, K.3
Yonekura, Y.4
Konishi, J.5
Yokoyama, A.6
-
147
-
-
28844468964
-
Nuclear medicine studies of the prostate, testes, and bladder
-
Jana, S., and Blaufox, M. D. (2006) Nuclear medicine studies of the prostate, testes, and bladder. Semin. Nucl. Med. 36, 51-72.
-
(2006)
Semin. Nucl. Med.
, vol.36
, pp. 51-72
-
-
Jana, S.1
Blaufox, M.D.2
-
148
-
-
33748260777
-
Fatty acid oxidation is a dominant bioenergetic pathway in prostate cancer
-
Liu, Y. (2006) Fatty acid oxidation is a dominant bioenergetic pathway in prostate cancer. Prostate Cancer Prostatic Dis. 9, 230-234.
-
(2006)
Prostate Cancer Prostatic Dis.
, vol.9
, pp. 230-234
-
-
Liu, Y.1
-
149
-
-
12844271620
-
Malignant gliomas in 2005: Where to go from here?
-
Fisher, P. G., and Buffler, P. A. (2005) Malignant gliomas in 2005: where to go from here? JAMA 293, 615-617.
-
(2005)
JAMA
, vol.293
, pp. 615-617
-
-
Fisher, P.G.1
Buffler, P.A.2
|