Pharmacological evidences for DFK167-sensitive presenilin-independent γ-secretase-like activity

Journal of Neurochemistry

Volumn 110, Issue 1, 2009, Pages 275-283

  Sevalle, Jean ^a   Ayral, Erwan ^b   Hernandez, Jean François ^b   Martinez, Jean ^b   Checler, Frédéric ^a  

^a INSTITUT DE PHARMACOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^b UNIVERSITÉ DE MONTPELLIER   (France)

Author keywords

secretase; Alzheimer's Disease; DFK167; Fibroblasts; Nicastrin; Presenilins

Indexed keywords

AMYLOID PRECURSOR PROTEIN; DFK 167; GAMMA SECRETASE; GAMMA SECRETASE INHIBITOR; LY 68458; N [N (3,5 DIFLUOROPHENACETYL)ALANYL]PHENYLGLYCINE TERT BUTYL ESTER; PHENYLGLYCINE; PRESENILIN 1; PRESENILIN 2; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SUBSTRATE; FLUOROMETRY; HUMAN; HUMAN CELL; NERVE CELL CULTURE; PRIORITY JOURNAL;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; BRAIN; CELL LINE; CELLS, CULTURED; DIPEPTIDES; ENZYME INHIBITORS; FIBROBLASTS; HUMANS; MICE; PEPTIDE FRAGMENTS; PRESENILINS; SENILE PLAQUES;

MURINAE;

EID: 67449110951     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2009.06131.x     Document Type: Article

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