메뉴 건너뛰기




Volumn 11, Issue 7, 2009, Pages 1669-1682

Molecular mechanisms responsible for the atheroprotective effects of laminar shear stress

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; ENDOTHELIN 1; GLUTAREDOXIN; GLUTATHIONE; GLUTATHIONE DISULFIDE; GLUTATHIONE PEROXIDASE 1; KRUPPEL LIKE FACTOR 2; LIPOPROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 7; MONOCYTE CHEMOTACTIC PROTEIN 1; NITRIC OXIDE; OXIDIZED LOW DENSITY LIPOPROTEIN; PROSTACYCLIN; PROTEIN 14 3 3; PROTEIN KINASE B; TRANSCRIPTION FACTOR; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

EID: 66749149330     PISSN: 15230864     EISSN: None     Source Type: Journal    
DOI: 10.1089/ars.2009.2487     Document Type: Review
Times cited : (109)

References (146)
  • 2
    • 0028940192 scopus 로고
    • Down-regulation of vascular adhesion molecule-1 by fluid shear stress in cultured mouse endothelial cells
    • Ando J, Tsuboi H, Korenaga R, Takada Y, Toyama S-N, Miyasaka M, and Kamiya A. Down-regulation of vascular adhesion molecule-1 by fluid shear stress in cultured mouse endothelial cells. Ann NY Acad Sci 748: 148-156, 1995.
    • (1995) Ann NY Acad Sci , vol.748 , pp. 148-156
    • Ando, J.1    Tsuboi, H.2    Korenaga, R.3    Takada, Y.4    Toyama, S.-N.5    Miyasaka, M.6    Kamiya, A.7
  • 3
    • 0028112586 scopus 로고
    • Shear stress inhibits adhesion of cultured mouse endothelial cells to lymphocytes by downregulating VCAM-1 expression
    • Ando J, Tsuboi H, Korenaga R, Takada Y, Toyama S-N, Miyasaka M, and Kamiya A. Shear stress inhibits adhesion of cultured mouse endothelial cells to lymphocytes by downregulating VCAM-1 expression. Am J Physiol 267: C679-687, 1994.
    • (1994) Am J Physiol , vol.267
    • Ando, J.1    Tsuboi, H.2    Korenaga, R.3    Takada, Y.4    Toyama, S.-N.5    Miyasaka, M.6    Kamiya, A.7
  • 4
    • 0034814130 scopus 로고    scopus 로고
    • Mechanism of temporal gradients in shear-induced ERK1/2 activation and proliferation in endothelial cells
    • Bao X, Lu C, and Frangos JA. Mechanism of temporal gradients in shear-induced ERK1/2 activation and proliferation in endothelial cells. Am J Physiol Heart Circ Physiol 281: H22-29, 2001.
    • (2001) Am J Physiol Heart Circ Physiol , vol.281
    • Bao, X.1    Lu, C.2    Frangos, J.A.3
  • 5
    • 0032943155 scopus 로고    scopus 로고
    • Temporal gradient in shear but not steady shear stress induces PDGF-A and MCP-1 expression in endothelial cells: Role of NO, NF kappa B, and egr-1
    • Bao X, Lu C, and Frangos JA. Temporal gradient in shear but not steady shear stress induces PDGF-A and MCP-1 expression in endothelial cells: role of NO, NF kappa B, and egr-1. Arterioscler Thromb Vasc Biol 19: 996-1003, 1999.
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 996-1003
    • Bao, X.1    Lu, C.2    Frangos, J.A.3
  • 6
    • 0032696285 scopus 로고    scopus 로고
    • A flow-activated chloride-selective membrane current in vascular endothelial cells
    • Barakat AI, Leaver EV, Pappone PA, and Davies PF. A flow-activated chloride-selective membrane current in vascular endothelial cells. Circ Res 85: 820-828, 1999.
    • (1999) Circ Res , vol.85 , pp. 820-828
    • Barakat, A.I.1    Leaver, E.V.2    Pappone, P.A.3    Davies, P.F.4
  • 7
    • 0025075164 scopus 로고
    • Hemodynamics and low density lipoprotein metabolism. Rates of low density lipo-protein incorporation and degradation along medial and lateral walls of the rabbit aorto-iliac bifurcation
    • Berceli SA, Warty VS, Sheppeck RA, Mandarino WA, Tanksale SK, and Borovetz HS. Hemodynamics and low density lipoprotein metabolism. Rates of low density lipo-protein incorporation and degradation along medial and lateral walls of the rabbit aorto-iliac bifurcation. Arteriosclerosis 10: 686-694, 1990.
    • (1990) Arteriosclerosis , vol.10 , pp. 686-694
    • Berceli, S.A.1    Warty, V.S.2    Sheppeck, R.A.3    Mandarino, W.A.4    Tanksale, S.K.5    Borovetz, H.S.6
  • 9
    • 0042388672 scopus 로고    scopus 로고
    • Flow-dependent regulation of endothelial nitric oxide synthase: Role of protein kinases
    • Boo YC and Jo H. Flow-dependent regulation of endothelial nitric oxide synthase: Role of protein kinases. Am J Physiol Cell Physiol 285: C499-508, 2003.
    • (2003) Am J Physiol Cell Physiol , vol.285
    • Boo, Y.C.1    Jo, H.2
  • 10
    • 33745080255 scopus 로고    scopus 로고
    • Coordinated regulation of endothelial nitric oxide synthase activity by phosphorylation and subcellular localization
    • Boo YC, Kim HJ, Song H, Fulton D, Sessa W, and Jo H. Coordinated regulation of endothelial nitric oxide synthase activity by phosphorylation and subcellular localization. Free Radic Biol Med 41: 144-153, 2006.
    • (2006) Free Radic Biol Med , vol.41 , pp. 144-153
    • Boo, Y.C.1    Kim, H.J.2    Song, H.3    Fulton, D.4    Sessa, W.5    Jo, H.6
  • 11
    • 0036479305 scopus 로고    scopus 로고
    • Shear stress stimulates phosphorylation of endothelial nitric-oxide synthase at Ser1179 by Akt-independent mechanisms. Role of protein kinase A
    • Boo YC, Sorescu G, Boyd N, Shiojima I, Walsh K, Du J, and Jo H. Shear stress stimulates phosphorylation of endothelial nitric-oxide synthase at Ser1179 by Akt-independent mechanisms. Role of protein kinase A. J Biol Chem 277: 3388-3396, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 3388-3396
    • Boo, Y.C.1    Sorescu, G.2    Boyd, N.3    Shiojima, I.4    Walsh, K.5    Du, J.6    Jo, H.7
  • 12
    • 0026032652 scopus 로고
    • Shear stress-induced release of nitric oxide from endothelial cells grown on beads
    • Buga GM, Gold ME, Fukuto JM, and Ignarro LJ. Shear stress-induced release of nitric oxide from endothelial cells grown on beads. Hypertension 17: 187-193, 1991.
    • (1991) Hypertension , vol.17 , pp. 187-193
    • Buga, G.M.1    Gold, M.E.2    Fukuto, J.M.3    Ignarro, L.J.4
  • 13
    • 11144328101 scopus 로고    scopus 로고
    • Flow-conditioned HUVECs support clustered leukocyte adhesion by coexpressing ICAM-1 and E-selectin
    • Burns MP and DePaola N. Flow-conditioned HUVECs support clustered leukocyte adhesion by coexpressing ICAM-1 and E-selectin. Am J Physiol Heart Circ Physiol 288: H194-204, 2005.
    • (2005) Am J Physiol Heart Circ Physiol , vol.288
    • Burns, M.P.1    DePaola, N.2
  • 14
    • 0034996180 scopus 로고    scopus 로고
    • Shear stress induces a time- and position-dependent increase in endothelial cell membrane fluidity
    • Butler PJ, Norwich G, Weinbaum S, and Chien S. Shear stress induces a time- and position-dependent increase in endothelial cell membrane fluidity. Am J Physiol Cell Physiol 280: C962-969, 2001.
    • (2001) Am J Physiol Cell Physiol , vol.280
    • Butler, P.J.1    Norwich, G.2    Weinbaum, S.3    Chien, S.4
  • 15
    • 0034634281 scopus 로고    scopus 로고
    • Endothelial dysfunction in cardiovascular diseases: The role of oxidant stress
    • Cai H and Harrison DG. Endothelial dysfunction in cardiovascular diseases: The role of oxidant stress. Circ Res 87: 840-844, 2000.
    • (2000) Circ Res , vol.87 , pp. 840-844
    • Cai, H.1    Harrison, D.G.2
  • 16
    • 0028937885 scopus 로고
    • Effect of inhibition of nitric oxide synthesis on the uptake of LDL and fibrinogen by arterial walls and other organs of the rat
    • Cardona-Sanclemente LE, and Born GV. Effect of inhibition of nitric oxide synthesis on the uptake of LDL and fibrinogen by arterial walls and other organs of the rat. Br J Pharmacol 114: 1490-1494, 1995.
    • (1995) Br J Pharmacol , vol.114 , pp. 1490-1494
    • Cardona-Sanclemente, L.E.1    Born, G.V.2
  • 17
    • 0014673564 scopus 로고
    • Arterial wall shear and distribution of early atheroma in man
    • Caro CG, Fitz-Gerald JM, and Schroter RC. Arterial wall shear and distribution of early atheroma in man. Nature 223: 1159-1160, 1969.
    • (1969) Nature , vol.223 , pp. 1159-1160
    • Caro, C.G.1    Fitz-Gerald, J.M.2    Schroter, R.C.3
  • 18
    • 0033603352 scopus 로고    scopus 로고
    • Mechanotransduction in response to shear stress. Roles of receptor tyrosine kinases, integrins, and Shc
    • Chen KD, Li YS, Kim M, Li S, Yuan S, Chien S, and Shyy JY. Mechanotransduction in response to shear stress. Roles of receptor tyrosine kinases, integrins, and Shc. J Biol Chem 274: 18393-18400, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 18393-18400
    • Chen, K.D.1    Li, Y.S.2    Kim, M.3    Li, S.4    Yuan, S.5    Chien, S.6    Shyy, J.Y.7
  • 21
    • 0031888812 scopus 로고    scopus 로고
    • Shear stress induces transforming growth factor-beta 1 release by arterial endothelial cells
    • Cucina A, Sterpetti AV, Borrelli V, Pagliei S, Cavallaro A, and D'Angelo LS. Shear stress induces transforming growth factor-beta 1 release by arterial endothelial cells. Surgery 123: 212-217, 1998.
    • (1998) Surgery , vol.123 , pp. 212-217
    • Cucina, A.1    Sterpetti, A.V.2    Borrelli, V.3    Pagliei, S.4    Cavallaro, A.5    D'Angelo, L.S.6
  • 22
    • 0025896795 scopus 로고
    • Endothelial expression of a mononuclear leukocyte adhesion molecule during atherogenesis
    • Cybulsky MI and Gimbrone MA, Jr. Endothelial expression of a mononuclear leukocyte adhesion molecule during atherogenesis. Science 251: 788-791, 1991.
    • (1991) Science , vol.251 , pp. 788-791
    • Cybulsky, M.I.1    Gimbrone Jr., M.A.2
  • 23
    • 34848858001 scopus 로고    scopus 로고
    • Biomechanical forces in atherosclerosis-resistant vascular regions regulate endothelial redox balance via phosphoinositol 3-kinase/Akt-dependent activation of Nrf2
    • Dai G, Vaughn S, Zhang Y, Wang ET, Garcia-Cardena G, and Gimbrone MA, Jr. Biomechanical forces in atherosclerosis-resistant vascular regions regulate endothelial redox balance via phosphoinositol 3-kinase/Akt-dependent activation of Nrf2. Circ Res 101: 723-733, 2007.
    • (2007) Circ Res , vol.101 , pp. 723-733
    • Dai, G.1    Vaughn, S.2    Zhang, Y.3    Wang, E.T.4    Garcia-Cardena, G.5    Gimbrone Jr., M.A.6
  • 24
    • 0000771048 scopus 로고
    • Endothelial cells, hemodynamic forces, and the localization of atherosclerosis
    • Ryan US, ed, Boca Raton, Florida: CRC;
    • Davies PF. Endothelial cells, hemodynamic forces, and the localization of atherosclerosis. In: Ryan US, ed. Endothelial Cells. Boca Raton, Florida: CRC; 1988: 123-139.
    • (1988) Endothelial Cells , pp. 123-139
    • Davies, P.F.1
  • 25
    • 0033950512 scopus 로고    scopus 로고
    • Spatial hemodynamics, the endothelium, and focal atherogenesis: A cell cycle link? [editorial; comment]
    • Davies PF. Spatial hemodynamics, the endothelium, and focal atherogenesis: A cell cycle link? [editorial; comment]. Circ Res 86: 114-116, 2000.
    • (2000) Circ Res , vol.86 , pp. 114-116
    • Davies, P.F.1
  • 27
    • 0027177190 scopus 로고
    • Endothelial cell adhesion in real time. Measurements in vitro by tandem scanning confocal image analysis
    • Davies PF, Robotewskyj A, and Griem ML. Endothelial cell adhesion in real time. Measurements in vitro by tandem scanning confocal image analysis. J Clin Invest 91: 2640-2652, 1993.
    • (1993) J Clin Invest , vol.91 , pp. 2640-2652
    • Davies, P.F.1    Robotewskyj, A.2    Griem, M.L.3
  • 28
    • 0035941411 scopus 로고    scopus 로고
    • Shear stress regulates endothelial nitric oxide synthase expression through c-Src by divergent signaling pathways
    • Davis ME, Cai H, Drummond GR, and Harrison DG. Shear stress regulates endothelial nitric oxide synthase expression through c-Src by divergent signaling pathways. Circ Res 89: 1073-1080, 2001.
    • (2001) Circ Res , vol.89 , pp. 1073-1080
    • Davis, M.E.1    Cai, H.2    Drummond, G.R.3    Harrison, D.G.4
  • 29
    • 0347683478 scopus 로고    scopus 로고
    • Shear stress regulates endothelial nitric-oxide synthase promoter activity through nuclear factor kappaB binding
    • Davis ME, Grumbach IM, Fukai T, Cutchins A, and Harrison DG. Shear stress regulates endothelial nitric-oxide synthase promoter activity through nuclear factor kappaB binding. J Biol Chem 279: 163-168, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 163-168
    • Davis, M.E.1    Grumbach, I.M.2    Fukai, T.3    Cutchins, A.4    Harrison, D.G.5
  • 30
    • 0029159779 scopus 로고
    • Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines
    • De Caterina R, Libby P, Peng HB, Thannickal VJ, Rajavashisth TB, Gimbrone MA Jr., Shin WS, and Liao JK. Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines. J Clin Invest 96: 60-68, 1995.
    • (1995) J Clin Invest , vol.96 , pp. 60-68
    • De Caterina, R.1    Libby, P.2    Peng, H.B.3    Thannickal, V.J.4    Rajavashisth, T.B.5    Gimbrone Jr., M.A.6    Shin, W.S.7    Liao, J.K.8
  • 31
    • 0032007564 scopus 로고    scopus 로고
    • Tumour necrosis factor alpha activates a p22phox-based NADH oxidase in vascular smooth muscle
    • De Keulenaer GW, Alexander RW, Ushio-Fukai M, Ishizaka N, and Griendling KK. Tumour necrosis factor alpha activates a p22phox-based NADH oxidase in vascular smooth muscle. Biochem J 329: 653-657, 1998.
    • (1998) Biochem J , vol.329 , pp. 653-657
    • De Keulenaer, G.W.1    Alexander, R.W.2    Ushio-Fukai, M.3    Ishizaka, N.4    Griendling, K.K.5
  • 32
    • 0036721376 scopus 로고    scopus 로고
    • Prolonged fluid shear stress induces a distinct set of endothelial cell genes, most specifically lung Kruppel-like factor (KLF2)
    • Dekker RJ, van Soest S, Fontijn RD, Salamanca S, de Groot PG, VanBavel E, Pannekoek H, and Horrevoets AJ. Prolonged fluid shear stress induces a distinct set of endothelial cell genes, most specifically lung Kruppel-like factor (KLF2). Blood 100: 1689-1698, 2002.
    • (2002) Blood , vol.100 , pp. 1689-1698
    • Dekker, R.J.1    van Soest, S.2    Fontijn, R.D.3    Salamanca, S.4    de Groot, P.G.5    VanBavel, E.6    Pannekoek, H.7    Horrevoets, A.J.8
  • 34
    • 0024522606 scopus 로고
    • Fluid flow stimulates tissue plasminogen activator secretion by cultured human endothelial cells
    • Diamond SL, Eskin SG, and McIntire LV. Fluid flow stimulates tissue plasminogen activator secretion by cultured human endothelial cells. Science 243: 1483-1485, 1989.
    • (1989) Science , vol.243 , pp. 1483-1485
    • Diamond, S.L.1    Eskin, S.G.2    McIntire, L.V.3
  • 35
    • 0033542476 scopus 로고    scopus 로고
    • Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation
    • Dimmeler S, Fleming I, Fisslthaler B, Hermann C, Busse R, and Zeiher AM. Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation. Nature 399: 601-605, 1999.
    • (1999) Nature , vol.399 , pp. 601-605
    • Dimmeler, S.1    Fleming, I.2    Fisslthaler, B.3    Hermann, C.4    Busse, R.5    Zeiher, A.M.6
  • 37
    • 0033051533 scopus 로고    scopus 로고
    • Upregulation of superoxide dismutase and nitric oxide synthase mediates the apoptosis-suppressive effects of shear stress on endothelial cells
    • Dimmeler S, Hermann C, Galle J, and Zeiher AM. Upregulation of superoxide dismutase and nitric oxide synthase mediates the apoptosis-suppressive effects of shear stress on endothelial cells. Arterioscler Thromb Vasc Biol 19: 656-664, 1999.
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 656-664
    • Dimmeler, S.1    Hermann, C.2    Galle, J.3    Zeiher, A.M.4
  • 40
    • 0035827676 scopus 로고    scopus 로고
    • Phosphorylation of Thr(495) regulates Ca2+/calmodulin-dependent endothelial nitric oxide synthase activity
    • Fleming I, Fisslthaler B, Dimmeler S, Kemp BE, and Busse R. Phosphorylation of Thr(495) regulates Ca2+/calmodulin-dependent endothelial nitric oxide synthase activity. Circ Res 88: E68-75, 2001.
    • (2001) Circ Res , vol.88
    • Fleming, I.1    Fisslthaler, B.2    Dimmeler, S.3    Kemp, B.E.4    Busse, R.5
  • 42
    • 0030906843 scopus 로고    scopus 로고
    • Molecular cloning and expression of a bovine endothelial inward rectifier potassium channel
    • Forsyth SE, Hoger A, and Hoger JH. Molecular cloning and expression of a bovine endothelial inward rectifier potassium channel. FEBS Lett 409: 277-282, 1997.
    • (1997) FEBS Lett , vol.409 , pp. 277-282
    • Forsyth, S.E.1    Hoger, A.2    Hoger, J.H.3
  • 45
    • 0033569924 scopus 로고    scopus 로고
    • Identification of flow-dependent endothelial nitric-oxide synthase phosphorylation sites by mass spectrometry and regulation of phosphorylation and nitric oxide production by the phosphatidylinositol 3-kinase inhibitor LY294002
    • Gallis B, Corthals GL, Goodlett DR, Ueba H, Kim F, Presnell SR, Figeys D, Harrison DG, Berk BC, Aebersold R, and Corson MA. Identification of flow-dependent endothelial nitric-oxide synthase phosphorylation sites by mass spectrometry and regulation of phosphorylation and nitric oxide production by the phosphatidylinositol 3-kinase inhibitor LY294002. J Biol Chem 274: 30101-30108, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 30101-30108
    • Gallis, B.1    Corthals, G.L.2    Goodlett, D.R.3    Ueba, H.4    Kim, F.5    Presnell, S.R.6    Figeys, D.7    Harrison, D.G.8    Berk, B.C.9    Aebersold, R.10    Corson, M.A.11
  • 46
    • 0035686891 scopus 로고    scopus 로고
    • Mechanosensitive endothelial gene expression profiles: Scripts for the role of hemodynamics in atherogenesis?
    • Garcia-Cardena G, Comander JI, Blackman BR, Anderson KR, and Gimbrone MA. Mechanosensitive endothelial gene expression profiles: Scripts for the role of hemodynamics in atherogenesis? Ann NY Acad Sci 947: 1-6, 2001.
    • (2001) Ann NY Acad Sci , vol.947 , pp. 1-6
    • Garcia-Cardena, G.1    Comander, J.I.2    Blackman, B.R.3    Anderson, K.R.4    Gimbrone, M.A.5
  • 47
    • 33845972654 scopus 로고    scopus 로고
    • Flow-activated chloride channels in vascular endothelium. Shear stress sensitivity, desensitization dynamics, and physiological implications
    • Gautam M, Shen Y, Thirkill TL, Douglas GC, and Barakat AI. Flow-activated chloride channels in vascular endothelium. Shear stress sensitivity, desensitization dynamics, and physiological implications. J Biol Chem 281: 36492-36500, 2006.
    • (2006) J Biol Chem , vol.281 , pp. 36492-36500
    • Gautam, M.1    Shen, Y.2    Thirkill, T.L.3    Douglas, G.C.4    Barakat, A.I.5
  • 48
    • 0017718392 scopus 로고
    • Endothelial cell morphology in areas of in vivo Evans blue uptake in the aorta of young pigs. II. Ultrastructure of the intima in areas of differing permeability to proteins
    • Gerrity RG, Richardson M, Somer JB, Bell FP, and Schwartz CJ. Endothelial cell morphology in areas of in vivo Evans blue uptake in the aorta of young pigs. II. Ultrastructure of the intima in areas of differing permeability to proteins. Am J Pathol 89: 313-334, 1977.
    • (1977) Am J Pathol , vol.89 , pp. 313-334
    • Gerrity, R.G.1    Richardson, M.2    Somer, J.B.3    Bell, F.P.4    Schwartz, C.J.5
  • 49
    • 0017679049 scopus 로고
    • Structural correlates of arterial endothelial permeability in the Evans blue model
    • Gerrity RG and Schwartz CJ. Structural correlates of arterial endothelial permeability in the Evans blue model. Prog Biochem Pharmacol 13: 134-137, 1977.
    • (1977) Prog Biochem Pharmacol , vol.13 , pp. 134-137
    • Gerrity, R.G.1    Schwartz, C.J.2
  • 50
    • 0032738983 scopus 로고    scopus 로고
    • Evidence for peroxynitrite as a signaling molecule in flow-dependent activation of c-Jun NH(2)-terminal kinase
    • Go YM, Patel RP, Maland MC, Park H, Beckman JS, Darley-Usmar VM, and Jo H. Evidence for peroxynitrite as a signaling molecule in flow-dependent activation of c-Jun NH(2)-terminal kinase. Am J Physiol 277: H1647-H1653, 1999.
    • (1999) Am J Physiol , vol.277
    • Go, Y.M.1    Patel, R.P.2    Maland, M.C.3    Park, H.4    Beckman, J.S.5    Darley-Usmar, V.M.6    Jo, H.7
  • 51
    • 0032478310 scopus 로고    scopus 로고
    • Modulation of GTPase activity of G proteins by fluid shear stress and phospholipid composition
    • Gudi S, Nolan JP, and Frangos JA. Modulation of GTPase activity of G proteins by fluid shear stress and phospholipid composition. Proc Natl Acad Sci USA 95: 2515-2519, 1998.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 2515-2519
    • Gudi, S.1    Nolan, J.P.2    Frangos, J.A.3
  • 52
    • 0029822797 scopus 로고    scopus 로고
    • Fluid flow rapidly activates G proteins in human endothelial cells. Involvement of G proteins in mechanochemical signal transduction
    • Gudi SR, Clark CB, and Frangos JA. Fluid flow rapidly activates G proteins in human endothelial cells. Involvement of G proteins in mechanochemical signal transduction. Circ Res 79: 834-839, 1996.
    • (1996) Circ Res , vol.79 , pp. 834-839
    • Gudi, S.R.1    Clark, C.B.2    Frangos, J.A.3
  • 53
    • 0034255365 scopus 로고    scopus 로고
    • The NF-kappa B signal transduction pathway in aortic endothelial cells is primed for activation in regions predisposed to atherosclerotic lesion formation
    • Hajra L, Evans AI, Chen M, Hyduk SJ, Collins T, and Cybulsky MI. The NF-kappa B signal transduction pathway in aortic endothelial cells is primed for activation in regions predisposed to atherosclerotic lesion formation. Proc Natl Acad Sci USA 97: 9052-9057, 2000.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 9052-9057
    • Hajra, L.1    Evans, A.I.2    Chen, M.3    Hyduk, S.J.4    Collins, T.5    Cybulsky, M.I.6
  • 54
    • 17644363312 scopus 로고    scopus 로고
    • The shear stress of keeping arteries clear
    • Harrison DG. The shear stress of keeping arteries clear. Nat Med 11: 375-376, 2005.
    • (2005) Nat Med , vol.11 , pp. 375-376
    • Harrison, D.G.1
  • 56
    • 0035986925 scopus 로고    scopus 로고
    • The cytoskeleton under external fluid mechanical forces: Hemodynamic forces acting on the endothelium
    • Helmke BP and Davies PF. The cytoskeleton under external fluid mechanical forces: hemodynamic forces acting on the endothelium. Ann Biomed Eng 30: 284-296, 2002.
    • (2002) Ann Biomed Eng , vol.30 , pp. 284-296
    • Helmke, B.P.1    Davies, P.F.2
  • 57
    • 0031443009 scopus 로고    scopus 로고
    • Shear stress inhibits H2O2-induced apoptosis of human endothelial cells by modulation of the glutathione redox cycle and nitric oxide synthase
    • Hermann C, Zeiher AM, and Dimmeler S. Shear stress inhibits H2O2-induced apoptosis of human endothelial cells by modulation of the glutathione redox cycle and nitric oxide synthase. Arterioscler Thromb Vasc Biol 17: 3588-3592, 1997.
    • (1997) Arterioscler Thromb Vasc Biol , vol.17 , pp. 3588-3592
    • Hermann, C.1    Zeiher, A.M.2    Dimmeler, S.3
  • 58
    • 0034465978 scopus 로고    scopus 로고
    • Function and regulation of prostaglandin synthase 2
    • Herschman HR. Function and regulation of prostaglandin synthase 2. Adv Exp Med Biol 469: 3-8, 1999.
    • (1999) Adv Exp Med Biol , vol.469 , pp. 3-8
    • Herschman, H.R.1
  • 59
    • 0142102540 scopus 로고    scopus 로고
    • Shear stress increases the amount of S-nitrosylated molecules in endothelial cells: Important role for signal transduction
    • Hoffmann J, Dimmeler S, and Haendeler J. Shear stress increases the amount of S-nitrosylated molecules in endothelial cells: Important role for signal transduction. FEBS Lett 551: 153-158, 2003.
    • (2003) FEBS Lett , vol.551 , pp. 153-158
    • Hoffmann, J.1    Dimmeler, S.2    Haendeler, J.3
  • 61
    • 0037131208 scopus 로고    scopus 로고
    • Fluid shear stress attenuates hydrogen peroxide-induced c-Jun NH2-terminal kinase activation via a glutathione reductase-mediated mechanism
    • Hojo Y, Saito Y, Tanimoto T, Hoefen RJ, Baines CP, Yamamoto K, Haendeler J, Asmis R, and Berk BC. Fluid shear stress attenuates hydrogen peroxide-induced c-Jun NH2-terminal kinase activation via a glutathione reductase-mediated mechanism. Circ Res 91: 712-718, 2002.
    • (2002) Circ Res , vol.91 , pp. 712-718
    • Hojo, Y.1    Saito, Y.2    Tanimoto, T.3    Hoefen, R.J.4    Baines, C.P.5    Yamamoto, K.6    Haendeler, J.7    Asmis, R.8    Berk, B.C.9
  • 65
    • 0031740430 scopus 로고    scopus 로고
    • Genetic analysis of NOS isoforms using nNOS and eNOS knockout animals
    • Huang PL and Lo EH. Genetic analysis of NOS isoforms using nNOS and eNOS knockout animals. Prog Brain Res 118: 13-25, 1998.
    • (1998) Prog Brain Res , vol.118 , pp. 13-25
    • Huang, P.L.1    Lo, E.H.2
  • 66
    • 36148991420 scopus 로고    scopus 로고
    • Flow patterns in three-dimensional porcine epicardial coronary arterial tree
    • Huo Y, Wischgoll T, and Kassab GS. Flow patterns in three-dimensional porcine epicardial coronary arterial tree. Am J Physiol Heart Circ Physiol 293: H2959-2970, 2007.
    • (2007) Am J Physiol Heart Circ Physiol , vol.293
    • Huo, Y.1    Wischgoll, T.2    Kassab, G.S.3
  • 67
    • 0346750816 scopus 로고    scopus 로고
    • Pulsatile versus oscillatory shear stress regulates NADPH oxidase subunit expression: Implication for native LDL oxidation
    • Hwang J, Ing MH, Salazar A, Lassegue B, Griendling K, Navab M, Sevanian A, and Hsiai TK. Pulsatile versus oscillatory shear stress regulates NADPH oxidase subunit expression: Implication for native LDL oxidation. Circ Res 93: 1225-1232, 2003.
    • (2003) Circ Res , vol.93 , pp. 1225-1232
    • Hwang, J.1    Ing, M.H.2    Salazar, A.3    Lassegue, B.4    Griendling, K.5    Navab, M.6    Sevanian, A.7    Hsiai, T.K.8
  • 69
    • 0042358676 scopus 로고    scopus 로고
    • Ligand independent activation of VEGF receptor 2 by fluid shear stress regulates activation of endothelial nitric oxide synthase
    • Jin ZG, Ueba H, Tanimoto T, Lungu AO, Frame MD, and Berk BC. Ligand independent activation of VEGF receptor 2 by fluid shear stress regulates activation of endothelial nitric oxide synthase. Circ Res 93: 354-363, 2003.
    • (2003) Circ Res , vol.93 , pp. 354-363
    • Jin, Z.G.1    Ueba, H.2    Tanimoto, T.3    Lungu, A.O.4    Frame, M.D.5    Berk, B.C.6
  • 70
    • 34047212750 scopus 로고    scopus 로고
    • Human T and natural killer cells possess a functional reninangiotensin system: Further mechanisms of angiotensin II-induced inflammation
    • Jurewicz M, McDermott DH, Sechler JM, Tinckam K, Takakura A, Carpenter CB, Milford E, and Abdi R. Human T and natural killer cells possess a functional reninangiotensin system: Further mechanisms of angiotensin II-induced inflammation. J Am Soc Nephrol 18: 1093-1102, 2007.
    • (2007) J Am Soc Nephrol , vol.18 , pp. 1093-1102
    • Jurewicz, M.1    McDermott, D.H.2    Sechler, J.M.3    Tinckam, K.4    Takakura, A.5    Carpenter, C.B.6    Milford, E.7    Abdi, R.8
  • 71
    • 0031584801 scopus 로고    scopus 로고
    • Lack of hemodynamic forces triggers apoptosis in vascular endothelial cells
    • Kaiser D, Freyberg MA, and Friedl P. Lack of hemodynamic forces triggers apoptosis in vascular endothelial cells. Biochem Biophys Res Commun 231: 586-590, 1997.
    • (1997) Biochem Biophys Res Commun , vol.231 , pp. 586-590
    • Kaiser, D.1    Freyberg, M.A.2    Friedl, P.3
  • 72
    • 0034599116 scopus 로고    scopus 로고
    • Lateral zone of cell-cell adhesion as the major fluid shear stress-related signal transduction site
    • Kano Y, Katoh K, and Fujiwara K. Lateral zone of cell-cell adhesion as the major fluid shear stress-related signal transduction site. Circ Res 86: 425-433, 2000.
    • (2000) Circ Res , vol.86 , pp. 425-433
    • Kano, Y.1    Katoh, K.2    Fujiwara, K.3
  • 73
    • 0034004826 scopus 로고    scopus 로고
    • Enhanced atherosclerosis and kidney dysfunction in eNOS(-/-)Apoe(-/-) mice are ameliorated by enalapril treatment
    • Knowles JW, Reddick RL, Jennette JC, Shesely EG, Smithies O, and Maeda N. Enhanced atherosclerosis and kidney dysfunction in eNOS(-/-)Apoe(-/-) mice are ameliorated by enalapril treatment. J Clin Invest 105: 451-458, 2000.
    • (2000) J Clin Invest , vol.105 , pp. 451-458
    • Knowles, J.W.1    Reddick, R.L.2    Jennette, J.C.3    Shesely, E.G.4    Smithies, O.5    Maeda, N.6
  • 74
    • 0033975855 scopus 로고    scopus 로고
    • Cutting edge: Heat shock protein (HSP) 60 activates the innate immune response: CD14 is an essential receptor for HSP60 activation of mononuclear cells
    • Kol A, Lichtman AH, Finberg RW, Libby P, and Kurt-Jones EA. Cutting edge: heat shock protein (HSP) 60 activates the innate immune response: CD14 is an essential receptor for HSP60 activation of mononuclear cells. J Immunol 164: 13-17, 2000.
    • (2000) J Immunol , vol.164 , pp. 13-17
    • Kol, A.1    Lichtman, A.H.2    Finberg, R.W.3    Libby, P.4    Kurt-Jones, E.A.5
  • 75
    • 0029950937 scopus 로고    scopus 로고
    • Acute reductions in blood flow and shear stress induce platelet-derived growth factor-A expression in baboon prosthetic grafts
    • Kraiss LW, Geary RL, Mattsson EJ, Vergel S, Au YP, and Clowes AW. Acute reductions in blood flow and shear stress induce platelet-derived growth factor-A expression in baboon prosthetic grafts. Circ Res 79: 45-53, 1996.
    • (1996) Circ Res , vol.79 , pp. 45-53
    • Kraiss, L.W.1    Geary, R.L.2    Mattsson, E.J.3    Vergel, S.4    Au, Y.P.5    Clowes, A.W.6
  • 76
    • 0021966255 scopus 로고
    • Pulsatile flow and atherosclerosis in the human carotid bifurcation. Positive correlation between plaque location and low oscillating shear stress
    • Ku DN, Giddens DP, Zarins CK, and Glagov S. Pulsatile flow and atherosclerosis in the human carotid bifurcation. Positive correlation between plaque location and low oscillating shear stress. Arteriosclerosis 5: 293-302, 1985.
    • (1985) Arteriosclerosis , vol.5 , pp. 293-302
    • Ku, D.N.1    Giddens, D.P.2    Zarins, C.K.3    Glagov, S.4
  • 77
    • 0028102136 scopus 로고
    • NO donors prevent integrin-induced leukocyte adhesion but not P-selectin-dependent rolling in postischemic venules
    • Kubes P, Kurose I, and Granger DN. NO donors prevent integrin-induced leukocyte adhesion but not P-selectin-dependent rolling in postischemic venules. Am J Physiol 267: H931-937, 1994.
    • (1994) Am J Physiol , vol.267
    • Kubes, P.1    Kurose, I.2    Granger, D.N.3
  • 78
    • 0025731835 scopus 로고
    • Nitric oxide: An endogenous modulator of leukocyte adhesion
    • Kubes P, Suzuki M, and Granger DN. Nitric oxide: An endogenous modulator of leukocyte adhesion. Proc Natl Acad Sci USA 88: 4651-4655, 1991.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 4651-4655
    • Kubes, P.1    Suzuki, M.2    Granger, D.N.3
  • 79
    • 0028004981 scopus 로고
    • Role of G proteins in shear stress-mediated nitric oxide production by endothelial cells
    • Kuchan MJ, Jo H, and Frangos JA. Role of G proteins in shear stress-mediated nitric oxide production by endothelial cells. Am J Physiol 267: C753-758, 1994.
    • (1994) Am J Physiol , vol.267
    • Kuchan, M.J.1    Jo, H.2    Frangos, J.A.3
  • 80
    • 0035943042 scopus 로고    scopus 로고
    • Accelerated atherosclerosis, aortic aneurysm formation, and ischemic heart disease in apolipoprotein E/endothelial nitric oxide synthase double-knockout mice
    • Kuhlencordt PJ, Gyurko R, Han F, Scherrer-Crosbie M, Aretz TH, Hajjar R, Picard MH, and Huang PL. Accelerated atherosclerosis, aortic aneurysm formation, and ischemic heart disease in apolipoprotein E/endothelial nitric oxide synthase double-knockout mice. Circulation 104: 448-454, 2001.
    • (2001) Circulation , vol.104 , pp. 448-454
    • Kuhlencordt, P.J.1    Gyurko, R.2    Han, F.3    Scherrer-Crosbie, M.4    Aretz, T.H.5    Hajjar, R.6    Picard, M.H.7    Huang, P.L.8
  • 81
    • 0037402442 scopus 로고    scopus 로고
    • Cellular mechanics and gene expression in blood vessels
    • Lehoux S and Tedgui A. Cellular mechanics and gene expression in blood vessels. J Biomech 36: 631-643, 2003.
    • (2003) J Biomech , vol.36 , pp. 631-643
    • Lehoux, S.1    Tedgui, A.2
  • 83
    • 0029828586 scopus 로고    scopus 로고
    • The Ras-JNK pathway is involved in shear-induced gene expression
    • Li YS, Shyy JY, Li S, Lee J, Su B, Karin M, and Chien S. The Ras-JNK pathway is involved in shear-induced gene expression. Mol Cell Biol 16: 5947-5954, 1996.
    • (1996) Mol Cell Biol , vol.16 , pp. 5947-5954
    • Li, Y.S.1    Shyy, J.Y.2    Li, S.3    Lee, J.4    Su, B.5    Karin, M.6    Chien, S.7
  • 85
    • 0035064951 scopus 로고    scopus 로고
    • Laminar flow inhibits TNF-induced ASK1 activation by preventing dissociation of ASK1 from its inhibitor 14-3-3
    • Liu Y, Yin G, Surapisitchat J, Berk BC, and Min W. Laminar flow inhibits TNF-induced ASK1 activation by preventing dissociation of ASK1 from its inhibitor 14-3-3. J Clin Invest 107: 917-923, 2001.
    • (2001) J Clin Invest , vol.107 , pp. 917-923
    • Liu, Y.1    Yin, G.2    Surapisitchat, J.3    Berk, B.C.4    Min, W.5
  • 86
    • 0026699032 scopus 로고
    • Physiological fluid shear stress causes downregulation of endothelin-1 mRNA in bovine aortic endothelium
    • Malek A and Izumo S. Physiological fluid shear stress causes downregulation of endothelin-1 mRNA in bovine aortic endothelium. Am J Physiol 263: C389-C396, 1992.
    • (1992) Am J Physiol , vol.263
    • Malek, A.1    Izumo, S.2
  • 87
    • 0027163936 scopus 로고
    • Regulation of endothelin-1 gene by fluid shear stress is transcriptionally mediated and independent of protein kinase-C and cAMP
    • Malek AM, Greene AL, and Izumo S. Regulation of endothelin-1 gene by fluid shear stress is transcriptionally mediated and independent of protein kinase-C and cAMP. Proc Natl Acad Sci USA 90: 5999-6003, 1993.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 5999-6003
    • Malek, A.M.1    Greene, A.L.2    Izumo, S.3
  • 88
    • 0028314277 scopus 로고
    • Endothelial expression of thrombomodulin is reversibly regulated by fluid shear stress
    • Malek AM, Jackman R, Rosenberg RD, and Izumo S. Endothelial expression of thrombomodulin is reversibly regulated by fluid shear stress. Circ Res 74: 852-860, 1994.
    • (1994) Circ Res , vol.74 , pp. 852-860
    • Malek, A.M.1    Jackman, R.2    Rosenberg, R.D.3    Izumo, S.4
  • 91
    • 0036278746 scopus 로고    scopus 로고
    • Tissue factor activity is upregulated in human endothelial cells exposed to oscillatory shear stress
    • Mazzolai L, Silacci P, Bouzourene K, Daniel F, Brunner H, and Hayoz D. Tissue factor activity is upregulated in human endothelial cells exposed to oscillatory shear stress. Thromb Haemost 87: 1062-1068, 2002.
    • (2002) Thromb Haemost , vol.87 , pp. 1062-1068
    • Mazzolai, L.1    Silacci, P.2    Bouzourene, K.3    Daniel, F.4    Brunner, H.5    Hayoz, D.6
  • 93
    • 0030711558 scopus 로고    scopus 로고
    • Nitric oxide synthases: Which, where, how, and why?
    • Michel T and Feron O. Nitric oxide synthases: Which, where, how, and why? J Clin Invest 100: 2146-2151, 1997.
    • (1997) J Clin Invest , vol.100 , pp. 2146-2151
    • Michel, T.1    Feron, O.2
  • 94
    • 0035947574 scopus 로고    scopus 로고
    • Coordinated control of endothelial nitric-oxide synthase phosphorylation by protein kinase C and the cAMP-dependent protein kinase
    • Michell BJ, Chen Zp Z, Tiganis T, Stapleton D, Katsis F, Power DA, Sim AT, and Kemp BE. Coordinated control of endothelial nitric-oxide synthase phosphorylation by protein kinase C and the cAMP-dependent protein kinase. J Biol Chem 276: 17625-17628, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 17625-17628
    • Michell, B.J.1    Chen, Z.Z.2    Tiganis, T.3    Stapleton, D.4    Katsis, F.5    Power, D.A.6    Sim, A.T.7    Kemp, B.E.8
  • 95
    • 26244457996 scopus 로고    scopus 로고
    • The role of the multidrug resistance protein-1 in modulation of endothelial cell oxidative stress
    • Mueller CF, Widder JD, McNally JS, McCann L, Jones DP, and Harrison DG. The role of the multidrug resistance protein-1 in modulation of endothelial cell oxidative stress. Circ Res 97: 637-644, 2005.
    • (2005) Circ Res , vol.97 , pp. 637-644
    • Mueller, C.F.1    Widder, J.D.2    McNally, J.S.3    McCann, L.4    Jones, D.P.5    Harrison, D.G.6
  • 96
    • 0027931392 scopus 로고
    • Shear stress selectively upregulates intercellular adhesion molecule-1 expression in cultured human vascular endothelial cells
    • Nagel T, Resnick N, Atkinson WJ, Dewey CF Jr., Gimbrone MA Jr. Shear stress selectively upregulates intercellular adhesion molecule-1 expression in cultured human vascular endothelial cells. J Clin Invest 94: 885-891, 1994.
    • (1994) J Clin Invest , vol.94 , pp. 885-891
    • Nagel, T.1    Resnick, N.2    Atkinson, W.J.3    Dewey Jr., C.F.4    Gimbrone Jr, M.A.5
  • 97
    • 0032944423 scopus 로고    scopus 로고
    • Mechanical stress-induced Ca2+ entry and Cl-current incultured human aortic endothelial cells
    • Nakao M, Ono K, Fujisawa S, and Iijima T. Mechanical stress-induced Ca2+ entry and Cl-current incultured human aortic endothelial cells. Am J Physiol 276: C238-249, 1999.
    • (1999) Am J Physiol , vol.276
    • Nakao, M.1    Ono, K.2    Fujisawa, S.3    Iijima, T.4
  • 98
    • 0037799923 scopus 로고    scopus 로고
    • Activation of PKC-epsilon and ERK1/2 participates in shear-induced endothelial MCP-1 expression that is repressed by nitric oxide
    • Ni CW, Wang DL, Lien SC, Cheng JJ, Chao YJ, and Hsieh HJ. Activation of PKC-epsilon and ERK1/2 participates in shear-induced endothelial MCP-1 expression that is repressed by nitric oxide. J Cell Physiol 195: 428-434, 2003.
    • (2003) J Cell Physiol , vol.195 , pp. 428-434
    • Ni, C.W.1    Wang, D.L.2    Lien, S.C.3    Cheng, J.J.4    Chao, Y.J.5    Hsieh, H.J.6
  • 99
    • 0027267272 scopus 로고
    • Shear stress elevates endothelial cGMP. Role of a potassium channel and G protein coupling
    • Ohno M, Gibbons GH, Dzau VJ, and Cooke JP. Shear stress elevates endothelial cGMP. Role of a potassium channel and G protein coupling. Circulation 88: 193-197, 1993.
    • (1993) Circulation , vol.88 , pp. 193-197
    • Ohno, M.1    Gibbons, G.H.2    Dzau, V.J.3    Cooke, J.P.4
  • 103
    • 0037135988 scopus 로고    scopus 로고
    • Evidence for a role of platelet endothelial cell adhesion molecule-1 in endothelial cell mechanosignal transduction: Is it a mechanoresponsive molecule?
    • Osawa M, Masuda M, Kusano K, and Fujiwara K. Evidence for a role of platelet endothelial cell adhesion molecule-1 in endothelial cell mechanosignal transduction: Is it a mechanoresponsive molecule? J Cell Biol 158: 773-785, 2002.
    • (2002) J Cell Biol , vol.158 , pp. 773-785
    • Osawa, M.1    Masuda, M.2    Kusano, K.3    Fujiwara, K.4
  • 106
    • 33746787216 scopus 로고    scopus 로고
    • The interaction of thioredoxin with Txnip: Evidence for formation of a mixed disulfide by disulfide exchange
    • Patwari P, Higgins LJ, Chutkow WA, Yoshioka J, and Lee RT. The interaction of thioredoxin with Txnip: Evidence for formation of a mixed disulfide by disulfide exchange. J Biol Chem 28: 21884-21891, 2006.
    • (2006) J Biol Chem , vol.28 , pp. 21884-21891
    • Patwari, P.1    Higgins, L.J.2    Chutkow, W.A.3    Yoshioka, J.4    Lee, R.T.5
  • 107
    • 0037180747 scopus 로고    scopus 로고
    • Genomic analysis of immediate/early response to shear stress in human coronary artery endothelial cells
    • Peters DG, Zhang XC, Benos PV, Heidrich-O'Hare E, and Ferrell RE. Genomic analysis of immediate/early response to shear stress in human coronary artery endothelial cells. Physiol Genomics 12: 25-33, 2002.
    • (2002) Physiol Genomics , vol.12 , pp. 25-33
    • Peters, D.G.1    Zhang, X.C.2    Benos, P.V.3    Heidrich-O'Hare, E.4    Ferrell, R.E.5
  • 108
    • 66749087489 scopus 로고    scopus 로고
    • Big mitogen-activated protein kinase (BMK1)/ERK5 protects endothelial cells from apoptosis
    • Pi X, Yan C, and Berk BC. Big mitogen-activated protein kinase (BMK1)/ERK5 protects endothelial cells from apoptosis. Circ Res 11: 11, 2003.
    • (2003) Circ Res , vol.11 , pp. 11
    • Pi, X.1    Yan, C.2    Berk, B.C.3
  • 109
    • 0022516979 scopus 로고
    • Flow-induced release of endothelium-derived relaxing factor
    • Rubanyi GM, Romero JC, and Vanhoutte PM. Flow-induced release of endothelium-derived relaxing factor. Am J Physiol 19: H1145-H1149, 1986.
    • (1986) Am J Physiol , vol.19
    • Rubanyi, G.M.1    Romero, J.C.2    Vanhoutte, P.M.3
  • 110
    • 0032520153 scopus 로고    scopus 로고
    • Direct evidence for the importance of endothelium-derived nitric oxide in vascular remodeling
    • Rudic RD, Shesely EG, Maeda N, Smithies O, Segal SS, and Sessa WC. Direct evidence for the importance of endothelium-derived nitric oxide in vascular remodeling. J Clin Invest 101: 731-736, 1998.
    • (1998) J Clin Invest , vol.101 , pp. 731-736
    • Rudic, R.D.1    Shesely, E.G.2    Maeda, N.3    Smithies, O.4    Segal, S.S.5    Sessa, W.C.6
  • 112
    • 0034698351 scopus 로고    scopus 로고
    • New role of glycosaminoglycans on the plasma membrane proposed by their interaction with phosphatidylcholine
    • Satoh A, Toida T, Yoshida K, Kojima K, and Matsumoto I. New role of glycosaminoglycans on the plasma membrane proposed by their interaction with phosphatidylcholine. FEBS Lett 477: 249-252, 2000.
    • (2000) FEBS Lett , vol.477 , pp. 249-252
    • Satoh, A.1    Toida, T.2    Yoshida, K.3    Kojima, K.4    Matsumoto, I.5
  • 113
    • 0027071668 scopus 로고
    • Shear stress-induced calcium transients in endothelial cells from human umbilical cord veins
    • Schwarz G, Callewaert G, Droogmans G, and Nilius B. Shear stress-induced calcium transients in endothelial cells from human umbilical cord veins. J Physiol Lond 458: 527-538, 1992.
    • (1992) J Physiol Lond , vol.458 , pp. 527-538
    • Schwarz, G.1    Callewaert, G.2    Droogmans, G.3    Nilius, B.4
  • 114
    • 0026648687 scopus 로고
    • Shear stress induced membrane currents and calcium transients in human vascular endothelial cells
    • Schwarz G, Droogmans G, and Nilius B. Shear stress induced membrane currents and calcium transients in human vascular endothelial cells. Pflugers Arch 421: 394-396, 1992.
    • (1992) Pflugers Arch , vol.421 , pp. 394-396
    • Schwarz, G.1    Droogmans, G.2    Nilius, B.3
  • 116
    • 0025912717 scopus 로고
    • Fluid flow decreases preproendothelin mRNA levels and suppresses endothelin-1 peptide release in cultured human endothelial cells
    • Sharefkin JB, Diamond SL, Eskin SG, McIntire LV, and Dieffenbach CW. Fluid flow decreases preproendothelin mRNA levels and suppresses endothelin-1 peptide release in cultured human endothelial cells. J Vasc Surg 14: 1-9, 1991.
    • (1991) J Vasc Surg , vol.14 , pp. 1-9
    • Sharefkin, J.B.1    Diamond, S.L.2    Eskin, S.G.3    McIntire, L.V.4    Dieffenbach, C.W.5
  • 118
    • 0028362189 scopus 로고
    • Fluid shear stress induces a biphasic response of human monocyte chemotactic protein 1 gene expression in vascular endothelium
    • Shyy YJ, Hsieh HJ, Usami S, and Chien S. Fluid shear stress induces a biphasic response of human monocyte chemotactic protein 1 gene expression in vascular endothelium. Proc Natl Acad Sci USA 91: 4678-4682, 1994.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 4678-4682
    • Shyy, Y.J.1    Hsieh, H.J.2    Usami, S.3    Chien, S.4
  • 119
    • 6344283050 scopus 로고    scopus 로고
    • Bone morphogenic protein 4 produced in endothelial cells by oscillatory shear stress induces monocyte adhesion by stimulating reactive oxygen species production from a nox1-based NADPH oxidase
    • Sorescu GP, Song H, Tressel SL, Hwang J, Dikalov S, Smith DA, Boyd NL, Platt MO, Lassegue B, Griendling KK, and Jo H. Bone morphogenic protein 4 produced in endothelial cells by oscillatory shear stress induces monocyte adhesion by stimulating reactive oxygen species production from a nox1-based NADPH oxidase. Circ Res 95: 773-779, 2004.
    • (2004) Circ Res , vol.95 , pp. 773-779
    • Sorescu, G.P.1    Song, H.2    Tressel, S.L.3    Hwang, J.4    Dikalov, S.5    Smith, D.A.6    Boyd, N.L.7    Platt, M.O.8    Lassegue, B.9    Griendling, K.K.10    Jo, H.11
  • 120
    • 0035929149 scopus 로고    scopus 로고
    • Nitrosylation. the prototypic redox-based signaling mechanism
    • Stamler JS, Lamas S, and Fang FC. Nitrosylation. the prototypic redox-based signaling mechanism. Cell 106: 675-683, 2001.
    • (2001) Cell , vol.106 , pp. 675-683
    • Stamler, J.S.1    Lamas, S.2    Fang, F.C.3
  • 123
    • 44849124443 scopus 로고    scopus 로고
    • Blood flow patterns in the proximal human coronary arteries: Relationship to atherosclerotic plaque occurrence
    • Suo J, Oshinski JN, and Giddens DP. Blood flow patterns in the proximal human coronary arteries: relationship to atherosclerotic plaque occurrence. Mol Cell Biomech 5: 9-18, 2008.
    • (2008) Mol Cell Biomech , vol.5 , pp. 9-18
    • Suo, J.1    Oshinski, J.N.2    Giddens, D.P.3
  • 124
    • 0035933127 scopus 로고    scopus 로고
    • Fluid shear stress inhibits TNF-alpha activation of JNK but not ERK1/2 or p38 in human umbilical vein endothelial cells: Inhibitory crosstalk among MAPK family members
    • Surapisitchat J, Hoefen RJ, Pi X, Yoshizumi M, Yan C, and Berk BC. Fluid shear stress inhibits TNF-alpha activation of JNK but not ERK1/2 or p38 in human umbilical vein endothelial cells: Inhibitory crosstalk among MAPK family members. Proc Natl Acad Sci USA 98: 6476-6481, 2001.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 6476-6481
    • Surapisitchat, J.1    Hoefen, R.J.2    Pi, X.3    Yoshizumi, M.4    Yan, C.5    Berk, B.C.6
  • 127
    • 0029790770 scopus 로고    scopus 로고
    • Identification of vascular endothelial genes differentially responsive to fluid mechanical stimuli: Cyclooxygenase-2, manganese superoxide dismutase, and endothelial cell nitric oxide synthase are selectively up-regulated by steady laminar shear stress
    • Topper JN, Cai J, Falb D, and Gimbrone MA, Jr. Identification of vascular endothelial genes differentially responsive to fluid mechanical stimuli: cyclooxygenase-2, manganese superoxide dismutase, and endothelial cell nitric oxide synthase are selectively up-regulated by steady laminar shear stress. Proc Natl Acad Sci USA 93: 10417-10422, 1996.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 10417-10422
    • Topper, J.N.1    Cai, J.2    Falb, D.3    Gimbrone Jr., M.A.4
  • 128
    • 0031833126 scopus 로고    scopus 로고
    • Laminar shear stress: Mechanisms by which endothelial cells transduce an atheroprotective force
    • Traub O and Berk BC. Laminar shear stress: mechanisms by which endothelial cells transduce an atheroprotective force. Arterioscler Thromb Vasc Biol 18: 677-685, 1998.
    • (1998) Arterioscler Thromb Vasc Biol , vol.18 , pp. 677-685
    • Traub, O.1    Berk, B.C.2
  • 129
    • 0029741925 scopus 로고    scopus 로고
    • Fluid flow inhibits endothelial adhesiveness. Nitric oxide and transcriptional regulation of VCAM-1
    • Tsao PS, Buitrago R, Chan JR, and Cooke JP. Fluid flow inhibits endothelial adhesiveness. Nitric oxide and transcriptional regulation of VCAM-1. Circulation 94: 1682-1689, 1996.
    • (1996) Circulation , vol.94 , pp. 1682-1689
    • Tsao, P.S.1    Buitrago, R.2    Chan, J.R.3    Cooke, J.P.4
  • 130
    • 0035801529 scopus 로고    scopus 로고
    • Activation of integrins in endothelial cells by fluid shear stress mediates Rho-dependent cytoskeletal alignment
    • Tzima E, del Pozo MA, Shattil SJ, Chien S, and Schwartz MA. Activation of integrins in endothelial cells by fluid shear stress mediates Rho-dependent cytoskeletal alignment. EMBO J 20: 4639-4647, 2001.
    • (2001) EMBO J , vol.20 , pp. 4639-4647
    • Tzima, E.1    del Pozo, M.A.2    Shattil, S.J.3    Chien, S.4    Schwartz, M.A.5
  • 133
    • 0028912689 scopus 로고    scopus 로고
    • Walpola PL, Gotlieb AI, Cybulsky MI, and Langille BL. Expression of ICAM-1 and VCAM-1 and monocyte adherence in arteries exposed to altered shear stress [published erratum appears in Arterioscler Thromb Vasc Biol 1995: 15: 429]. Arterioscler Thromb Vasc Biol 15: 2-10, 1995.
    • Walpola PL, Gotlieb AI, Cybulsky MI, and Langille BL. Expression of ICAM-1 and VCAM-1 and monocyte adherence in arteries exposed to altered shear stress [published erratum appears in Arterioscler Thromb Vasc Biol 1995: 15: 429]. Arterioscler Thromb Vasc Biol 15: 2-10, 1995.
  • 134
    • 11144259754 scopus 로고    scopus 로고
    • Pulsatile flow increases the expression of eNOS, ET-1, and prostacyclin in a novel in vitro coculture model of the retinal vasculature
    • Walshe TE, Ferguson G, Connell P, O'Brien C, and Cahill PA. Pulsatile flow increases the expression of eNOS, ET-1, and prostacyclin in a novel in vitro coculture model of the retinal vasculature. Invest Ophthalmol Vis Sci 46: 375-382, 2005.
    • (2005) Invest Ophthalmol Vis Sci , vol.46 , pp. 375-382
    • Walshe, T.E.1    Ferguson, G.2    Connell, P.3    O'Brien, C.4    Cahill, P.A.5
  • 135
    • 0031589157 scopus 로고    scopus 로고
    • Does elevated nitric oxide production enhance the release of prostacyclin from shear stressed aortic endothelial cells?
    • Wang W and Diamond SL. Does elevated nitric oxide production enhance the release of prostacyclin from shear stressed aortic endothelial cells? Biochem Biophys Res Commun 233: 748-751, 1997.
    • (1997) Biochem Biophys Res Commun , vol.233 , pp. 748-751
    • Wang, W.1    Diamond, S.L.2
  • 136
    • 33845619005 scopus 로고    scopus 로고
    • Shear stress stabilizes NF-E2-related factor 2 and induces antioxidant genes in endothelial cells: Role of reactive oxygen/nitrogen species
    • Warabi E, Takabe W, Minami T, Inoue K, Itoh K, Yamamoto M, Ishii T, Kodama T, and Noguchi N. Shear stress stabilizes NF-E2-related factor 2 and induces antioxidant genes in endothelial cells: Role of reactive oxygen/nitrogen species. Free Radic Biol Med 42: 260-269, 2007.
    • (2007) Free Radic Biol Med , vol.42 , pp. 260-269
    • Warabi, E.1    Takabe, W.2    Minami, T.3    Inoue, K.4    Itoh, K.5    Yamamoto, M.6    Ishii, T.7    Kodama, T.8    Noguchi, N.9
  • 138
    • 36348979264 scopus 로고    scopus 로고
    • Relative reduction of endothelial nitric-oxide synthase expression and transcription in atherosclerosis-prone regions of the mouse aorta and in an in vitro model of disturbed flow
    • Won D, Zhu SN, Chen M, Teichert AM, Fish JE, Matouk CC, Bonert M, Ojha M, Marsden PA, and Cybulsky MI. Relative reduction of endothelial nitric-oxide synthase expression and transcription in atherosclerosis-prone regions of the mouse aorta and in an in vitro model of disturbed flow. Am J Pathol 171: 1691-1704, 2007.
    • (2007) Am J Pathol , vol.171 , pp. 1691-1704
    • Won, D.1    Zhu, S.N.2    Chen, M.3    Teichert, A.M.4    Fish, J.E.5    Matouk, C.C.6    Bonert, M.7    Ojha, M.8    Marsden, P.A.9    Cybulsky, M.I.10
  • 139
    • 0032949402 scopus 로고    scopus 로고
    • Flow regulation of ecNOS and Cu/Zn SOD mRNA expression in porcine coronary arterioles
    • Woodman CR, Muller JM, Rush JW, Laughlin MH, and Price EM. Flow regulation of ecNOS and Cu/Zn SOD mRNA expression in porcine coronary arterioles. Am J Physiol 276: H1058-1063, 1999.
    • (1999) Am J Physiol , vol.276
    • Woodman, C.R.1    Muller, J.M.2    Rush, J.W.3    Laughlin, M.H.4    Price, E.M.5
  • 140
    • 0344875019 scopus 로고    scopus 로고
    • Thioredoxin: A key regulator of cardiovascular homeostasis
    • Yamawaki H, Haendeler J, and Berk BC. Thioredoxin: A key regulator of cardiovascular homeostasis. Circ Res 93: 1029-1033, 2003.
    • (2003) Circ Res , vol.93 , pp. 1029-1033
    • Yamawaki, H.1    Haendeler, J.2    Berk, B.C.3
  • 141
    • 0141506872 scopus 로고    scopus 로고
    • Chronic physiological shear stress inhibits tumor necrosis factor-induced proinflammatory responses in rabbit aorta perfused ex vivo
    • Yamawaki H, Lehoux S, and Berk BC. Chronic physiological shear stress inhibits tumor necrosis factor-induced proinflammatory responses in rabbit aorta perfused ex vivo. Circulation 108: 1619-1625, 2003.
    • (2003) Circulation , vol.108 , pp. 1619-1625
    • Yamawaki, H.1    Lehoux, S.2    Berk, B.C.3
  • 142
    • 14644401702 scopus 로고    scopus 로고
    • Fluid shear stress inhibits vascular inflammation by decreasing thioredoxin-interacting protein in endothelial cells
    • Yamawaki H, Pan S, Lee RT, and Berk BC. Fluid shear stress inhibits vascular inflammation by decreasing thioredoxin-interacting protein in endothelial cells. J Clin Invest 115: 733-738, 2005.
    • (2005) J Clin Invest , vol.115 , pp. 733-738
    • Yamawaki, H.1    Pan, S.2    Lee, R.T.3    Berk, B.C.4
  • 143
    • 34547899189 scopus 로고    scopus 로고
    • Glycocalyx modulates the motility and proliferative response of vascular endothelium to fluid shear stress
    • Yao Y, Rabodzey A, and Dewey CF, Jr. Glycocalyx modulates the motility and proliferative response of vascular endothelium to fluid shear stress. Am J Physiol Heart Circ Physiol 293: H1023-1030, 2007.
    • (2007) Am J Physiol Heart Circ Physiol , vol.293
    • Yao, Y.1    Rabodzey, A.2    Dewey Jr., C.F.3
  • 144
    • 50149114693 scopus 로고    scopus 로고
    • Regulation of G protein-coupled receptor activities by the platelet-endothelial cell adhesion molecule, PECAM-1
    • Yeh JC, Otte LA, and Frangos JA. Regulation of G protein-coupled receptor activities by the platelet-endothelial cell adhesion molecule, PECAM-1. Biochemistry 47: 9029-9039, 2008.
    • (2008) Biochemistry , vol.47 , pp. 9029-9039
    • Yeh, J.C.1    Otte, L.A.2    Frangos, J.A.3
  • 145
    • 9144223075 scopus 로고    scopus 로고
    • Ebselen inhibits tumor necrosis factor-alpha-induced c-Jun N-terminal kinase activation and adhesion molecule expression in endothelial cells
    • Yoshizumi M, Fujita Y, Izawa Y, Suzaki Y, Kyaw M, Ali N, Tsuchiya K, Kagami S, Yano S, Sone S, and Tamaki T. Ebselen inhibits tumor necrosis factor-alpha-induced c-Jun N-terminal kinase activation and adhesion molecule expression in endothelial cells. Exp Cell Res 292: 1-10, 2004.
    • (2004) Exp Cell Res , vol.292 , pp. 1-10
    • Yoshizumi, M.1    Fujita, Y.2    Izawa, Y.3    Suzaki, Y.4    Kyaw, M.5    Ali, N.6    Tsuchiya, K.7    Kagami, S.8    Yano, S.9    Sone, S.10    Tamaki, T.11
  • 146
    • 54449102397 scopus 로고    scopus 로고
    • Increased endothelial mitogen-activated protein kinase phosphatase-1 expression suppresses proinflammatory activation at sites that are resistant to atherosclerosis
    • Zakkar M, Chaudhury H, Sandvik G, Enesa K, Luong le A, Cuhlmann S, Mason JC, Krams R, Clark AR, Haskard DO, and Evans PC. Increased endothelial mitogen-activated protein kinase phosphatase-1 expression suppresses proinflammatory activation at sites that are resistant to atherosclerosis. Circ Res 103: 726-732, 2008.
    • (2008) Circ Res , vol.103 , pp. 726-732
    • Zakkar, M.1    Chaudhury, H.2    Sandvik, G.3    Enesa, K.4    Luong le, A.5    Cuhlmann, S.6    Mason, J.C.7    Krams, R.8    Clark, A.R.9    Haskard, D.O.10    Evans, P.C.11


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.