Function and regulation of prostaglandin synthase 2

Advances in Experimental Medicine and Biology

Volumn 469, Issue , 2000, Pages 3-8

  Herschman, H R ^a   Xie, W ^a   Reddy, S ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARACHIDONIC ACID; ENDOTOXIN; LEUKOTRIENE; LIPOPOLYSACCHARIDE; PHOSPHOLIPASE; PROSTACYCLIN; PROSTAGLANDIN; PROSTAGLANDIN SYNTHASE; PROSTANOID; THROMBOXANE;

ANIMAL CELL; BONE MARROW CELL; CONFERENCE PAPER; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENDOTHELIUM CELL; ENZYME ACTIVITY; GENE EXPRESSION; GENETIC CODE; IMMUNOMODULATION; INFLAMMATION; LYMPHOID CELL; NONHUMAN; PRIORITY JOURNAL; REACTION ANALYSIS; SIGNAL TRANSDUCTION;

ANIMALS; ARACHIDONIC ACID; CYCLOOXYGENASE 2; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; INFLAMMATION; ISOENZYMES; MAST CELLS; MEMBRANE PROTEINS; MODELS, BIOLOGICAL; PHOSPHOLIPASES A; PROSTAGLANDIN D2; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PROSTAGLANDINS; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 0034465978     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Conference Paper

References (27)

1. Primary response genes induced by growth factors and tumor promoters
2. The TIS genes, primary response genes induced by growth factors and tumor promoters
3. TIS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue
4. Structure of the Mitogen-Inducible TIS10 gene and demonstration that the TIS10 encoded protein is a functional prostaglandin G/H synthase
5. Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing
6. A serum-and glucocorticoid-regulated 4-kilobase mRNA encodes a cyclooxygenase-related protein
7. Identification of an immediate early gene, phs-B, whose protein product has prostaglandin synthase/cyclooxygenase activity
8. Human cyclooxygenase-2 cDNA
9. Molecular cloning of human prostaglandin endoperoxide synthase type II and demonstration of expression in response to cytokines
10. Cloning and characterization of a growth factor-inducible cyclooxygenase gene from rat intestinal epithelial cells
11. Inflammation, reproduction, cancer, and all that.... The regulation and role of the inducible prostaglandin synthase
12. Prostaglandin synthase 2
13. Towards a better aspirin
14. Dexamethasone inhibits mitogen iduction of the T1S10 prostaglandin synthase/cyclooxygenase gene
15. Ligand-induced prostaglandin synthesis requires expression of the TIS10/PGS-2 prostaglandin synthase gene in murine fibroblasts and macrophages
16. Different intracellular locations for prostaglandin endoperoxide H synthases-1 and -2
17. v-src induces prostaglandin synthase 2 gene expression by activation of the c-Jun N-terminal kinase and the c-Jun transcription factor
18. Transcriptional regulation of prostaglandin synthase 2 gene expression by platelet derived growth factor and serum
19. Transcriptional regulation of man prostaglandin-endoperoxide synthase-2 gene by lipopolysaccharide and phorbol ester in vascular endothelial cells. Involvement of both nuclear factor for interleukin-6 expression site and cAMP response element
20. Transcriptional roles of nuclear factor kappa B and nuclear factor-interleukin-6 in the tumor necrosis factor alpha-dependent induction of cyclooxygenase-2 in MC3T3-E1 cells
21. 2 production in mast cells
22. IgE-dependent activation of cytokine-primed mouse cultured mast cells induces a delayed phase of prostaglandin D2 generation via prostaglandin endoperoxide synthase-2
23. 2 in activated mast cells
24. A heparin-sensitive phospholipase A2 and prostaglandin endoperoxide synthase-2 are functionally linked in the delayed phase of prostaglandin D2 generation in mouse bone marrow-derived mast cells
25. 2 plays a role in arachidonic acid release and eicosanoid biosynthesis by mast cells
26. 2 that mediates prostaglandin production in mast cells
27. 2 and distal prostaglandin synthase 1