Activation of integrins in endothelial cells by fluid shear stress mediates Rho-dependent cytoskeletal alignment

EMBO Journal

Volumn 20, Issue 17, 2001, Pages 4639-4647

  Tzima, Eleni ^a   Del Pozo, Miguel Angel ^a   Shattil, Sanford J ^a   Chien, Shu ^b   Schwartz, Martin Alexander ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

Inside out signaling; Integrin affinity state; Integrins; Mechanotransduction

Indexed keywords

ALPHA5 INTEGRIN; BETA3 INTEGRIN; GUANOSINE TRIPHOSPHATASE; INTEGRIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; SCLEROPROTEIN; UNCLASSIFIED DRUG;

ADAPTATION; ANIMAL CELL; ARTICLE; ATHEROGENESIS; CYTOSKELETON; ENDOTHELIUM CELL; EXTRACELLULAR MATRIX; FLUID FLOW; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; SHEAR STRESS; SIGNAL TRANSDUCTION;

ANIMALS; AORTA; CATTLE; CELLS, CULTURED; CULTURE MEDIA, SERUM-FREE; CYTOSKELETON; ENDOTHELIUM, VASCULAR; EXTRACELLULAR MATRIX PROTEINS; FIBRONECTINS; GREEN FLUORESCENT PROTEINS; INTEGRINS; KINETICS; LUMINESCENT PROTEINS; PROTEIN CONFORMATION; RECEPTORS, VITRONECTIN; RECOMBINANT PROTEINS; RHO GTP-BINDING PROTEINS; STRESS, MECHANICAL; TIME FACTORS; TRANSFECTION;

ANIMALIA; BOVINAE;

EID: 0035801529     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/20.17.4639     Document Type: Article

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