Ligand-independent activation of vascular endothelial growth factor receptor 2 by fluid shear stress regulates activation of endothelial nitric oxide synthase

Circulation Research

Volumn 93, Issue 4, 2003, Pages 354-363

  Jin, Zheng Gen ^a   Ueba, Hiroto ^b   Tanimoto, Tatsuo ^b   Lungu, Andreea O ^b   Frame, Mary D ^b   Berk, Bradford C ^b  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^b NONE

Author keywords

Endothelial nitric oxide synthase; Mechanotransduction; Shear stress; Vascular endothelial growth factor receptor; Vasodilation

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; LIGAND; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN TYROSINE KINASE; VASCULOTROPIN RECEPTOR 2;

ANIMAL CELL; ARTERIOLE; ARTERY BLOOD FLOW; ARTERY TONE; ARTICLE; ATHEROGENESIS; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME INHIBITION; LAMINAR FLOW; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RECEPTOR UPREGULATION; SHEAR STRESS; VASODILATATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; ANTIBODIES, MONOCLONAL; BENZOQUINONES; BLOOD VESSELS; CELL LINE; CHEEK; CRICETINAE; ENDOTHELIUM, VASCULAR; ENZYME ACTIVATION; ENZYME INHIBITORS; GENISTEIN; INTEGRIN ALPHAVBETA3; LACTAMS, MACROCYCLIC; LIGANDS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; QUINONES; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; STRESS, MECHANICAL; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2; VASODILATION;

EID: 0042358676     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000089257.94002.96     Document Type: Article

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