Fluid flow inhibits endothelial adhesiveness: Nitric oxide and transcriptional regulation of VCAM-1

Circulation

Volumn 94, Issue 7, 1996, Pages 1682-1689

  Tsao, Philip S ^a   Buitrago, Ricardo ^a   Chan, Jason R ^a   Cooke, John P ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

adhesion molecules; atherosclerosis; blood flow; endothelium derived factors; free radicals

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; LOW DENSITY LIPOPROTEIN; NITRIC OXIDE; SUPEROXIDE; TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1;

ARTERY BLOOD FLOW; ARTERY ENDOTHELIUM; ARTICLE; ATHEROGENESIS; CELL ADHESION; CONTROLLED STUDY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SHEAR STRESS; TRANSCRIPTION REGULATION;

EID: 0029741925     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.94.7.1682     Document Type: Article

References (56)

1. Rokitansky C. The pathological anatomy of the organs of respiration and circulation. In: Day GE, trans. A Manual of Pathological Anatomy. London, UK: Sydenham Society; 1952; vol 4.
2. Virchow R; Glance F, trans. Cellular Pathology as Based Upon Physiological and Pathological Histology. London, UK: Churchill; 1860.
3. Montenegro MR, Eggen DA. Topography of atherosclerosis in the coronary arteries. Lab Invest. 1968;18:586-593.
4. Sinzinger H, Siberbauer K, Auerswald W. Quantitative investigation of sudanophilic lesions around the aortic ostia of human fetuses, newborns and children. Blood Vessels. 1980;17:44-52.
5. Cornhill JF, Barrett WA, Herderick EE, Mahley RW, Fry DF. Topographic study of sudanophilic lesions in cholesterol-fed minipigs by image analysis. Atherosclerosis. 1985;5:415-426.
6. Glagov S, Zarins C, Giddens DP, Ku DN. Hemodynamics and atherosclerosis: insights and perspectives gained from studies of human arteries. Arch Pathol Lab Med. 1988;112:1018-1031.
7. Asakura T, Karino T. Flow patterns and spatial distribution of atherosclerotic lesions in human coronary arteries. Circ Res. 1990;66: 1045-1066.
8. Walpola PL, Gottlieb AI, Langille BL. Monocyte adhesion and changes in endothelial cell number, morphology, and F-actin distribution elicited by low shear stress in vivo. Am J Pathol. 1993; 142:1392-1400.
9. Walpola PL, Gottlieb AI, Cybulsky MI, Langille BL. Expression of ICAM-1 and VCAM-1 and monocyte adherence in arteries exposed to altered shear stress. Anterioscler Thromb Vasc Biol. 1995;15:2-10.
10. Schwenke DE, Carew TE, Quantification in vivo of increased LDL content and rate of LDL degradation in normal rabbit aorta occurring at sites susceptible to early atherosclerotic lesions. Circ Res. 1988; 62:699-710.
11. Berliner JA, Navab M, Fogelman AM, Frank JS, Demer LL, Edwards PA, Watson AD, Lusis AJ. Atherosclerosis: basic mechanisms: oxidation, inflammation, and genetics. Circulation. 1995;91:2488-2496.
12. Cybulsky MI, Gimbrone MA Jr. Endothelial expression of a mononuclear leukocyte adhesion molecule during atherogenesis. Science. 1991;251:788-791.
13. Li H, Cybulsky MI, Gimbrone MA Jr, Libby P. An atherogenic diet rapidly induces VCAM-1, a cytokine-regulatable mononuclear leukocyte adhesion molecule, in rabbit aortic endothelium. Arterioscler Thromb. 1993;13:197-204.
14. Ohtsuka A, Ando J, Korenaga R, Kamiya A, Toyama-Sorimachi N, Miyasaka M. The effect of flow on the expression of vascular adhesion molecule-1 by cultured mouse endothelial cells. Biochem Biophys Res Commun. 1993;193:303-310.
15. Marui N, Offerman MK, Swerlick R, Kunsch C, Rosen CA, Ahmad M, Alexander RW, Medford RM. Vascular cell adhesion molecule1 (VCAM-1) gene transcription and expression are regulated through an antioxidant-sensitive mechanism in human vascular endothelial cells. J Clin Invest. 1993;92:1866-1874.
16. Pohl U, Holtz J, Busse R, Bassenge E. Crucial role of endothelium in the vasodilator response to increase flow in vivo. Hypertension. 1986;8:37-44.
17. Cooke JP, Stamler JS, Andon N, Davies PR, Loscalzo J. Flow stimulates endothelial cells to release a nitrovasodilator that is potentiated by reduced thiol. Am J Physiol. 1990;(Heart Circ Physiol 28); H804-H812.
18. Cooke JP, Rossitch E, Andon N, Loscalzo J, Dzau VJ. Flow activates an endothelial potassium channel to release an endogenous nitrovasodilator. J Clin Invest. 1991;88:1663-1671.
19. Clancy RM, Leszczynska P, Piziak J, Abramson SB. Nitric oxide, an endothelial cell relaxation factor, inhibits neutrophil superoxide anion production via a direct action on NADPH oxidase. J Clin Invest. 1992;90:1116-1121.
20. Niu XF, Smith CW, Kubes P. Intracellular oxidative stress induced by nitric oxide synthesis inhibition increases endothelial cell adhesion to neutrophils. Circ Res. 1994;74:1133-1140.
21. Bussolari SR, Dewey CF Jr, Gimbrone MA Jr. Apparatus for subjecting living cells to fluid shear stress. Rev Sci Instrum. 1982; 53:1851-1854.
22. Ohno M, Gibbons GH, Dzau VJ, Cooke JP. Shear stress elevates endothelial cGMP: role of a potassium channel and G protein coupling. Circulation. 1993;88:193-197.
23. Tsao PS, Lewis NP, Alpert SA, Cooke JP. Fluid flow decreases endothelial adhesiveness for monocytes: role of nitric oxide. Circulation. 1995;92:3513-3519.
24. Pagano PJ, Tornheim K, Cohen RA. Superoxide anion production by rabbit thoracic aorta: effect of endothelium-derived nitric oxide. Am J Physiol. 1993;265:H707-H712.
25. Dignam JD, Lebovitz RM, Roeder RG. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 1983;11:1475-1489.
26. Weber C, Erl W, Pietsch A, Ströbel M, Ziegler-Heitbrock HW, Weber PC. Antioxidants inhibit monocyte adhesion by suppressing nuclear factor-κB mobilization and induction of vascular cell adhesion molecule-1 in endothelial cells stimulated to generate radicals. Arterioscler Thromb. 1994;14:1665-1673.
27. Ohara Y, Petersen TE, Harrison DG. Hypercholesterolemia increases endothelial superoxide anion production. J Clin Invest. 1993;91: 2546-2551.
28. Harris NR, Russell JM, Granger DN. Mediators of endotoxin-induced leukocyte adhesion in mesenteric postcapillary venules. Circ Shock. 1994;43:155-160.
29. Lehr HA, Backer M, Marklund SL, Hubner C, Arfors KE, Kohl-schutter A, Messmer K. Superoxide-dependent stimulation of leukocyte adhesion by oxidatively modified LDL in vivo. Anterioscler Thromb. 1992;12:824-829.
30. Heim KF, Thomas G, Ramwell PW. Effect of substituted arginine compounds on Superoxide production in the rabbit aorta. J Pharmacol Exp Ther. 1991;257:1130-1135.
31. Beckman JS, Crow JP. Pathological implications of nitric oxide, superoxide and peroxynitrite formation. Biochem Soc Trans. 1993; 21:330-334.
32. Hogg N, Kalyanaraman B, Joseph J, Struck A, Parthasarathy S. Inhibition of low-density lipoprotein oxidation by nitric oxide: potential role in atherogenesis. FEBS Lett. 1993;334:170-174.
33. Yates MT, Lambert LE, Whitten JP, McDonald I, Mano M, Ku G, Mao SJT. A protective role for nitric oxide in the oxidative modification of low density lipoproteins by mouse macrophages. FEBS Lett. 1992;309:135-138.
34. Henkel T, Machleidt T, Alkalay I, Kronke M, Ben-Neriah Y, Baeuerle PA. Rapid proteolysis of I kappa B-alpha is necessary for activation of transcription factor NF-kappa B. Nature. 1993;365: 182-185.
35. Devary Y, Rosette C, DiDonato JA, Karin M. NF-kappa B activation by ultraviolet light not dependent on a nuclear signal. Science. 1993;261:1442-1445.
36. Peng HB, Libby P, Liao JK. Induction and stabilization off kappa B alpha by nitric oxide mediates inhibition of NF-kappa B. J Biol Chem. 1995;270:14214-14219.
37. DeCaterina R, Libby P, Peng H-B, Thannickal VJ, Rajavashisth TB, Gimbrone MA Jr, Shin WS, Liao JK. Nitric oxide decreases cytokine-induced endothelial activation. J Clin Invest. 1995;96:60-68.
38. Zeiher AM, Fisslthaler B, Schray-Utz B, Busse R. Nitric oxide modulates the expression of monocyte chemoattractant protein 1 in cultured human endothelial cells. Circ Res. 1995;76:980-986.
39. Kurose I, Kubes P, Wolf R, Anderson DC, Paulson J, Miyasaka M, Granger DN. Inhibition of nitric oxide production: mechanisms of vascular albumin leakage. Circ Res. 1993;73:164-171.
40. Kuchan MJ, Frangos JA. Shear stress regulates endothelin-1 release I via protein kinase C and cGMP in cultured endothelial cells. Am J Physiol. 1993;264:H150-H156.
41. Resnick N, Collins T, Atkinson W, Bonthron DT, Dewey CF Jr, Gimbrone MA Jr. Platelet-derived growth factor B chain promoter contains a cis-acting fluid shear-stress-responsive element. Proc Natl Acad Sci USA. 1993;90:4591-4595.
42. Marsden PA, Heng HHQ, Scherer SW, Stewart RJ, Hall AY, Shi XM, Tsui L, Schappert KT. Structure and chromosomal localization of the human constitutive endothelial nitric oxide synthase. J Biol Chem. 1993;268:17478-17488.
43. Nishida K, Harrison DG, Navas JP, Fisher AA, Dockery SP, Uematsu M, Nerem RM, Alexander RW, Murphy TJ. Molecular cloning and characterization of the constitutive bovine aortic endothelial cell nitric oxide synthase. J Clin Invest. 1992;90:2090-2096.
44. Frangos JA, Eskin SG, Mcintire LV, Ives CL. Flow effects prosta-cyclin production of cultured human endothelial cells. Science. 1985; 227:1477-1479.
45. Bath PM, Hassall DG, Gladwin AM, Palmer RMJ, Martin JF. Nitric oxide and prostacyclin: divergence of inhibitory effects on monocyte chemotaxis and adhesion to endothelium in vitro. Anterioscler Thromb. 1991;11:254-260.
46. Kanai AJ, Strauss HC, Truskey GA, Crews AL, Grunfeld S, Malinski T. Shear stress induces ATP-independent transient nitric oxide re-lease from vascular endothelial cells, measured directly with a por-phyrinic microsensor. Circ Res. 1995;77:284-293.
47. Richard MJ, Davis LD, Jacobson NL. The domestic goat: a useful model to determine effects of diet and exercise on cholesterol accu-mulation in the body. Comp Biochem Physiol. 1990;95:275-280.
48. Haskell WL, Alderman EL, Fair JM, Maron DJ, Mackey SF, Superko HR, Williams PT, Johnstone IM, Champagne MA, Krauss RM, Far-quhar JW. Effects of intensive multiple risk factor reduction on cor-onary atherosclerosis and clinical cardiac events in men and women with coronary artery disease: the Stanford Coronary Risk Intervention Project (SCRIP). Circulation. 1994;89:975-990.
49. Sessa WC, Pritchard K, Seyedi N, Wang J, Hintze TH. Chronic exercise in dogs increases coronary vascular nitric oxide production and endothelial cell nitric oxide synthase gene expression. Circ Res. 1994;74:349-353.
50. McLenahan JM, William JK, Fish RD, Ganz P, Selwyn AP. Loss of flow-mediated endothelium-dependent dilation occurs early in the development of atherosclerosis. Circulation. 1991;84:1273-1278.
51. Cooke JP, Singer AH, Tsao PS, Zera P, Rowan RA, Billingham ME. Anti-atherogenic effects of L-arginine in the hypercholesterolemic rabbit. J Clin Invest. 1992;90:1168-1172.
52. Wang B, Singer A, Tsao P, Drexler H, Kosek J, Cooke JP. Dietary arginine prevents atherogenesis in the coronary artery of the hypercholesterolemic rabbit. J Am Coll Cardiol. 1994;23:452-458.
53. Tsao PS, McEvoy LM, Drexler H, Butcher EC, Cooke JP. Enhanced endothelial adhesiveness in hypercholesterolemia is attenuated by Larginine. Circulation, 1994;89:2176-2182.
54. Cayette AJ, Palacino JJ, Horten K, Cohen RA. Chronic inhibition of nitric oxide production accelerates neointima formation and impairs endothelial function in hypercholesterolemic rabbits. Arterioscler Thromb. 1994;14:753-759.
55. Naruse K, Shimizu K, Muramatsu M, Toki Y, Miyazaki Y, Okumura K, Hashimoto H, Ito T. Long-term inhibition of NO synthesis promotes atherosclerosis in the hypercholesterolemic rabbit thoracic aorta: PGH2 does not contribute to impaired endothelium-dependent relaxation. Arterioscler Thromb. 1994;14: 746-752.
56. Lefer AM, Ma XL. Decreased basal nitric oxide release in hypercholesterolemia increases neutrophil adherence to rabbit coronary artery endothelium. Arterioscler Thromb. 1993;13:771-776.