The Ras-JNK pathway is involved in shear-induced gene expression

Molecular and Cellular Biology

Volumn 16, Issue 11, 1996, Pages 5947-5954

  Li, Yi Shuan ^a   Shyy, John Y J ^a   Li, Song ^a   Lee, Jongdae ^a   Su, Bing ^b,d   Karin, Michael ^b   Chien, Shu ^a,c  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b San Diego   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF TEXAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATE; LUCIFERASE; PHORBOL 13 ACETATE 12 MYRISTATE; PHOSPHOTRANSFERASE; PROTEIN P21;

ANIMAL CELL; ARTICLE; ATHEROSCLEROSIS; CATTLE; CONTROLLED STUDY; GENE; GENE EXPRESSION; NONHUMAN; PRIORITY JOURNAL; SHEAR STRESS; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIUM;

ANIMALIA; BOS TAURUS;

EID: 0029828586     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.16.11.5947     Document Type: Article

References (49)

1. Angel, P., and M. Karin. 1991. The role of Jun, Fos and the AP-1 complex in cell proliferation and transformation. Biochim. Biophys. Acta 1072:129-157.
2. Bogoyevitch, M. A., A. J. Ketterman, S. J. Fuller, C. J. Marshall, and P. H. Sugden. 1995. Ischemia and reperfusion activate Jun N-terminal protein kinase (JNKs) in the adult rat ventricular myocardium. Circulation 92:1-571.
3. Boguski, M. S., and F. McCormick. 1993. Proteins regulating Ras and its relatives. Nature (London) 366:643-654.
4. Chardin, P., J. H. Camonis, N. W. Gale, L. van Aelst, J. Schlessinger, M. H. Wigler, and D. Bar-Sagi. 1988. Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2. Science 260:1338-1343.
5. Cobb, M. H., T. G. Boulton, and D. J. Robbins. 1991. Extracellular signal-regulated kinases: ERKs in progress. Cell Regul. 2:965-978.
6. Coso, O. A., M. Chiariello, J.-C. Yu, H. Teramoto, P. Crespo, N. Xu, T. Mild, and J. S. Gutkind. 1995. The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway. Cell 81:1137-1146.
7. Davies, P. F. 1995. Flow-mediated endothelial mechanotransduction. Physiol. Rev. 75:519-560.
8. Davies, P. F., A. Robotewskyj, and M. L. Griem. 1994. Quantitative studies of endothelial cell adhesion. Directional remodeling of focal adhesion sites in response to flow forces. J. Clin. Invest. 93:2031-2038.
9. Deng, T., and M. Karin. 1994. c-Fos transcriptional activity stimulated by H-Ras-activated protein kinase distinct from JNK and ERK. Nature (London) 371:171-175.
10. Dérijard, B., M. Hibi, I.-H. Wu, T. Barrett, B. Su, T. Deng, M. Karin, and R. J. Davis. 1994. JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain. Cell 76:1025-1037.
11. ras in activation of extracellular signal-regulated kinase 2. Nature (London) 357:602-604.
12. Downward, J., J. D. Graves, P. H. Warne, S. Rayter, and D. A. Cantrell. 1990. Stimulation of p21ras upon T-cell activation. Nature (London) 346:719-723.
13. Egan, S. E., B. W. Giddings, M. W. Brooks, L. Buday, A. M. Sizeland, and R. A. Weinberg. 1993. Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation. Nature (London) 363:45-51.
14. Feig, L. A., and G. M. Cooper. 1988. Inhibition of NIH 3T3 cell proliferation by a mutant ras protein with preferential affinity for GDP. Mol. Cell. Biol. 8:3235-3243.
15. Frangos, J., S. G. Eskin, L. B. McIntire, and C. L. Ives. 1985. Flow effects on prostacyclin production by cultured human endothelial cells. Science 227: 1477-1479.
16. Frost, J. A., T. D. Geppert, M. H. Cobb, and J. R. Feramisco. 1994. A requirement for extracellular signal-regulated kinase (ERK) function in the activation of AP-1 by Ha-Ras, phorbol 12-myristate 13-acetate, and serum. Proc. Natl. Acad. Sci. USA 91:3844-3848.
17. Galcheva-Gargova, Z., B. Derijard, I.-H. Wu, and R. J. Davis. 1994. An osmosensing signal transduction pathway in mammalian cells. Science 265: 806-808.
18. Gille, H., A. Sharrocks, and P. Shaw. 1992. Phosphorylation of p62 TCF by MAP kinase stimulates ternary complex formation at c-Fos promoter. Nature (London) 358:414-417.
19. Hibi, M., A. Lin, T. Smeal, A. Minden, and M. Karin. 1993. Identification of an oncoprotein and UV responsive protein kinase that binds and potentiates the c-Jun activation domain. Genes Dev. 7:2135-2148.
20. Hill, C. S., and R. Trisman. 1995. Transcriptional regulation by extracellular signals: mechanisms and specificity. Cell 80:199-211.
21. Hsieh, H.-J., N.-Q. Li, and J. A. Frangos. 1992. Shear-induced platelet-derived growth factor gene expression in human endothelial cells is mediated by protein kinase C. J. Cell. Physiol. 150:552-558.
22. Hsieh, H.-J., N.-Q. Li, and J. A. Frangos. 1993. Pulsatile and steady flow induces c-fos expression in human endothelial cells. J. Cell. Physiol. 154: 143-151.
23. Kim, S.-M., S. Jalali, J. Y.-J. Shyy, and S. Chien. 1996. The TRE-mediated gene expression in response to shear stress involves SH2-containing molecules. FASEB J. 10:A24.
24. Kolch, W., G. Heidecker, P. Lloyd, and U. R. Rapp. 1991. Raf-1 protein kinase is required for growth of induced NIH/3T3 cells. Nature (London) 349:426-428.
25. Kuchan, M. J., H. Jo, and J. A. Frangos. 1994. Role of G proteins in shear stress-mediated nitric oxide production by endothelial cells. Am. J. Physiol. 267:C753-C758.
26. Kyriakis, J. M., P. Banerjee, E. Nikolakaki, T. Dai, E. A. Rubie, M. F. Ahmad, J. Avruch, and J. R. Woodgett. 1994. The stress-activated protein kinase subfamily of c-Jun kinases. Nature (London) 369:156-160.
27. Lange-Carter, C. A., and G. L. Johnson. 1994. Ras-dependent growth factor regulation of MEK kinase in PC12 cells. Science 265:1458-1461.
28. Leevers, S. J., H. F. Paterson, and C. J. Marshall. 1994. Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane. Nature (London) 372:739-745.
29. Lin, A., A. Minden, H. Martinetto, F. X. Claret, C. Lange-Carter, F. Mercurio, G. L. Johnson, and M. Karin. 1995. Identification of a dual specificity kinase that activates the Jun kinases and p38-Mpk2. Science 268:286-290.
30. Marais, R., J. Wynne, and R. Treisman. 1993. The SRF accessory protein ELS-1 contains a growth factor regulated transcription domain. Cell 73:381-393.
31. Marshall, C. J. 1995. Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. Cell 80:179-185.
32. Minden, A., A. Lin, F.-X. Claret, A. Abo, and M. Karin. 1995. Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs. Cell 81:1147-1157.
33. Minden, A., A. Lin, M. McMahon, C. Lange-Carter, B. Derijard, R. J. Davis, G. L. Johnson, and M. Karin. 1994. Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK. Science 266:1719-1723.
34. Minden, A., A. Lin, T. Smeal, B. Dérijard, M. Cobb, R. Davis, and M. Karin. 1994. c-Jun N-terminal phosphorylation correlates with activation of the JNK subgroup but not the ERK subgroup of mitogen-activated protein kinases. Mol. Cell. Biol. 14:6683-6688.
35. Morooka, H., J. V. Bonyentre, C. Pombo, J. Kyriakis, and T. Force. 1995. Ischemia and reperfusion target ATF-2 and c-Jun to cAMP response elements and to an AP-1 site from the c-Jun promoter by activating an ATF-2 kinase. Circulation 92:I-371.
36. Robbins, D. J., E. Zhen, H. Owaki, C. A. Vanderbilt, D. Ebert, T. D. Geppert, and M. H. Cobb. 1993. Regulation and properties of extracellular signal-regulated protein kinases 1 and 2 in vitro. J. Biol. Chem. 268:5097-5106.
37. Rozengurt, E. 1992. Growth factors and cell proliferation. Curr. Opin. Cell Biol. 4:161-165.
38. Russell, M., C. A. Lange-Carter, and G. L. Johnson. 1995. Direct interaction between Ras and the kinase domain of mitogen-activate protein kinase kinase kinase (MEKK1). J. Biol. Chem. 270:11757-11760.
39. Sakaue, M., D. Bowtell, and M. Kasuga. 1995. A dominant-negative mutant of mSOS1 inhibits insulin-induced Ras activation and reveals Ras-dependent and -independent insulin signaling pathways. Mol. Cell. Biol. 15:379-388.
40. Shyy, Y.-J., H.-J. Hsieh, S. Usami, and S. Chien. 1994. Fluid shear stress induces a biphasic response of human monocyte chemotactic protein-1 gene expression in vascular endothelium. Proc. Natl. Acad. Sci. USA 91:4678-4682.
41. Shyy, Y.-J., M.-C. Lin, J. Han, Y. Lu, M. Petrime, and S. Chien. 1995. The cis-acting phorbol ester "12-O-tetradecanoylphorbol 13-acetate"-responsive element is involved in shear stress-induced monocyte chemotactic protein 1 gene expression. Proc. Natl. Acad. Sci. USA 92:8069-8073.
42. Sluss, H. K., T. Barrett. B. Dérijard, and R. J. Davis. 1994. Signal transduction by tumor necrosis factor mediated by JNK protein kinases. Mol. Cell. Biol. 14:8376-8384.
43. Stokoe, D., S. G. MacDonald, K. Cadwallader, M. Symons, and J. F. Hancock. 1994. Activation of Raf as a result of recruitment of the plasma membrane. Science 264:1463-1467.
44. 43a. Su, B. Unpublished results.
45. Su, B., E. Jacinto, M. Hibi, T. Kallunki, M. Karin, and Y. Ben-Neriah. 1994. JNK is involved in signal integration during costimulation of T lymphocytes. Cell 77:727-736.
46. Taverse, S., N. Gomez, H. Paterson, C. Marshall, and P. Cohen. 1992. Sustained activation of the mitogen-activated protein (MAP) kinase cascade may be required for differentiation of PC12 cells. Comparison of the effects of nerve growth factor and epidermal growth factor. Biochem. J. 288:351-355.
47. Thomas, S. M., M. DeMarco, G. D'Arcangelo, S. Halegoua, and J. S. Brugge. 1992. Ras is essential for nerve growth factor- and phorbol ester-induced tyrosine phosphorylation of MAP kinases. Cell 68:1031-1040.
48. Wang, N., J. P. Butler, and D. E. Ingber. 1993. Mechanotransduction across the cell surface and through the cytoskeleton. Science 260:1124-1127.
49. Yan, M., T. Dai, J. C. Deak, J. M. Kyriakis, L. I. Zon, J. R. Woodgett, and D. J. Templeton. 1994. Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1. Nature (London) 372:798-800.